An unexpected role of CLASP1 in radiation response and S-phase regulation of head and neck cancer cells. by Reinout H de Roest, Marijke Buijze, Myrthe Veth, Klaas de Lint, Govind Pai, Martin A Rooimans, Rob M F Wolthuis, Arjen Brink, Jos B Poell, Ruud H Brakenhoff

“…Clonogenic assay confirmed the radiosensitizing effect of CLASP1 knockout. Functional analysis showed that CLASP1 knockout has major impact during S-phase, and resulted in mitotic cells with broken chromosomes and cell death. …”
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FUNCTIONAL AND PRAGMATIC SPACE OF POLITICAL INTERNET COMMUNICATION by Elena Dobrynina

“…With the reference to functional analysis of the phenomenon under consideration within the framework of communicative-pragmatic approach, the author concludes a special form of borderline character, existential kind, personality-oriented type of communication under conditions of universal rules of political discourse construction. …”
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Privacy-preserving multi-dimensional multi-function data aggregation scheme in smart grid by WANG Yuanyuan, HAN Yiliang, WU Liqiang, LI Yu, YAO Wujun, WU Xuguang, ZHU Shuaishuai

“…However, achieving functional analysis of such data, especially its multi-dimensionalization and multi-functional operation, without compromising user privacy has been identified as an urgent problem. …”
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Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. by Alan P Reed, Giovanna Bucci, Firdaus Abd-Wahab, Stephen J Tucker

“…This missense variant is located at the extracellular surface of the M2 transmembrane helix and by using a combination of structural modelling and further functional analysis we also show that this highly-conserved threonine residue is critical for the correct function of other K2P channels. …”
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Common Practices and Methodologies in Scientific Functional Characterization of Surface Topography by Abbass Walid, Matthias Eifler

“…Based on the results, untapped potential in functional analysis can be revealed and the use of, e.g., function-oriented parameters or a direct measurement of the angular distribution can be recommended for a wider range of applications.…”
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Existence, Uniqueness, and Mittag–Leffler–Ulam Stability Results for Cauchy Problem Involving ψ-Caputo Derivative in Banach and Fréchet Spaces by Choukri Derbazi, Zidane Baitiche, Mouffak Benchohra, G. N’Guérékata

“…The techniques used are a variety of tools for functional analysis. More specifically, we apply Weissinger’s fixed point theorem and Banach contraction principle with respect to the Chebyshev and Bielecki norms to obtain the uniqueness of solution on bounded and unbounded domains in a Banach space. …”
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Characterization and genomic analysis of Lactiplantibacillus plantarum LP8 as a probiotic candidate for medical applicationsNCBI by Nirusna Jehma, Nattarika Chaichana, Jirasa Boonsan, Kamonnut Singkhamanan, Monwadee Wonglapsuwan, Rattanaruji Pomwised, Sarunyou Chusri, Komwit Surachat

“…This study presents the whole genome sequencing (WGS) and functional analysis of Lactiplantibacillus plantarum LP8, a promising probiotic strain, is presented in this research. …”
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Functional reconstitution of plant plasma membrane H+-ATPase into giant unilamellar vesicles by Huriye D. Uzun, Ekaterina Malysenko, Bo H. Justesen, Thomas Günther Pomorski

“…Addressing these factors is essential for the successful formation and functional analysis of AHA2 and other P-type ATPases in experimental settings.…”
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Technological innovation system in agribusiness: motors and evolution by Telmo Lena Garcez, Marcelo Fernandes Pacheco Dias

“…The study's results identified two functionalities: analysis of the chain as a whole and coordination of the actors involved in the system. …”
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SLC10A3 regulates ferroptosis of glioblastoma through the STAT3/GPX4 pathway by Qian Sun, Haoran Lu, Fan’en Yuan, Qingyu Zhao, Yuxin Wei, Ronggui Wang, Qianxue Chen, Baohui Liu

“…In this research, bioinformatics revealed that SLC10A3 is upregulated in GBM and correlates with poor patient prognosis. Functional analysis showed that SLC10A3 regulates GBM growth and progression through ferroptosis and that silencing SLC10A3 enhances sensitivity to the ferroptosis inducer Erastin. …”
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Coupled Resonance Fiber-Optic SPR Sensor Based on TRIZ by Cuilan Zhu, Haodi Zhai, Yonghao Wang, Xiangru Suo, Tianyu Zhu, Shuowei Jin

“…To identify the key challenges faced by current SPR sensors, methods such as functional analysis, causal analysis, and the Nine-Window method are employed. …”
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Deep mutational scanning identifies Cas1 and Cas2 variants that enhance type II-A CRISPR-Cas spacer acquisition by Raphael Hofmann, Calvin Herman, Charlie Y. Mo, Jacob Mathai, Luciano A. Marraffini

“…While the structure of the integrase complex has been described, a detailed functional analysis of the spacer acquisition machinery is lacking. …”
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Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3 by Dewu Ding, Meineng Wang, Meili Wu, Chengzhi Gan, Pu Wu

“…Generally, the use of these electron acceptors is mainly achieved through electron transfer proteins and their interactions which will dynamically change across different environmental conditions in cells. Therefore, functional analysis of condition-specific molecular networks can reveal biological information on electron transfer processes. …”
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Gene duplication and clustering underlie the conservation and diversification of benzylisoquinoline alkaloid biosynthesis in plants by Changheng Shan, Xuan Zhou, Jiaojiao Zhu, Aatif Rashid, Jianhua Wang, Ning An, Changjian Zhang, Wenjuan Ji, Baosong Cai, Ke Wu, Sheng Wang, Zhenhua Liu

“…This study characterizes key enzymes in Houttuynia cordata—including 6-OMT, NMT, CYP80B, and 4’OMT—that form BIA backbones and uncovers a CYP80G-mediated phenol coupling reaction in isoboldine biosynthesis. Functional analysis reveals conservation of BIA backbone formation genes between Magnoliids and Ranunculales, with evidence of gene duplication and neofunctionalization in H. cordata. …”
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PCR-mediated repeated chromosome splitting in Saccharomyces cerevisiae by Minetaka Sugiyama, Shigehito Ikushima, Toshimasa Nakazawa, Yoshinobu Kaneko, Satoshi Harashima

“…Chromosome engineering is playing an increasingly important role in the functional analysis of genomes. A simple and efficient technology for manipulating large chromosomal segments is key to advancing these analyses. …”
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A COMPUTATIONAL MODEL FOR A DIFFERENTIAL EQUATION WITH EMPIRICAL FUNCTIONS BASED ON THE INTEGRAL EQUATIONS FREDHOLM OF THE FIRST KIND by Igor Eduardovich Naats, Victoria Igorevna Naats, Roman Andreevich Ryskalenko

“…To obtain the approximate solution of this problem requires construction of appropriate regularization algorithms based on the methods of the theory of functional analysis and ill-posed problems. In the present work is the construction of the approximate solution of odes with specified boundary conditions, are the so-called singular integrals. …”
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METHOD FOR SOLVING ILL-POSED PROBLEMS FOR DIFFERENTIAL EQUATIONS WITH APPROXIMATELY GIVEN FUNCTIONS BASED ON THE REPRESENTATION OF THE SOLUTION OF INTEGRAL EQUATIONS by Igor' Eduardovich Naats, Victoria Igorevna Naats, Roman Andreyevich Ryskalenko

“…To obtain the approximate solution of this problem requires construction of appropriate regularization algorithms based on the methods of the theory of functional analysis and ill-posed problems. In the present work is the construction of the approximate solution of odes with specified boundary conditions, are the so-called singular integrals. …”
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Russian firewall screening tools for secured systems by A. M. Sadykov, R. R. Yamaletdinov, D. I. Sabirova

“…Systematization, description and analysis are used as research methods. In this work functional analysis will be carried out in relation to the following solutions: «Universal security gateway «UserGate», security complex «Continent 4», hardware and software complex «ViPNet xFirewall 5», «Firewall with Ideco UTM intrusion detection system». …”
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Research progress of NAC transcription factors in woody plants by Huan Zhang, Huan Zhang, Jia Zhao, Jia Zhao, Tongxing Zhang, Tongxing Zhang, Guiying Wang, Zhixiao Han, Yuemei Meng, Jingran Bi, Yachao Ren, Yachao Ren, Minsheng Yang, Minsheng Yang

“…Most of the research is still at the stages of gene cloning, structural identification, and functional analysis; the specific downstream target genes and their molecular mechanisms remain unclear. …”
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Dynamic Analysis of a Standby System with Retrial Strategies and Multiple Working Vacations by Changjiang Lai, Ehmet Kasim, Ahmadjan Muhammadhaji

“…We investigated its well−posedness and asymptotic behavior using the theory of the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>C</mi><mn>0</mn></msub><mo>−</mo></mrow></semantics></math></inline-formula>semigroup in the functional analysis. First, the corresponding model was transformed into an abstract Cauchy problem in Banach space by introducing the state space, the main operator, and its domain of definition. …”
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