CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension by Lea Strohm, Henning Ubbens, Dominika Mihalikova, Alexander Czarnowski, Paul Stamm, Michael Molitor, Stefanie Finger, Matthias Oelze, Dorothee Atzler, Philip Wenzel, Philipp Lurz, Thomas Münzel, Christian Weber, Esther Lutgens, Andreas Daiber, Steffen Daub

“…Cardiovascular disease is the leading cause of disease burden and death worldwide and is fueled by vascular inflammation. CD40L–CD40–TRAF signaling is involved in the progression of atherosclerosis and drives the development of coronary heart disease (CHD). …”
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Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives by Dagmawi Woldesenbet, Yalewayker Tegegne, Abdulhakim Mussema, Elias Tamene, Kemal Mohamed, Wagaw Abebe, Melese Mekuria, Kasahun Bogale, Habtamu Geremew, Mufta Muzemil Shifa, Mulugeta Aemero Tegegne

“…However, recent data suggests a concerning resurgence in malaria cases, potentially fueled by emerging drug and insecticide resistance. …”
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Concentrated Solar Power and Photovoltaic Systems: A New Approach to Boost Sustainable Energy for All (Se4all) in Rwanda by Noel Hagumimana, Jishi Zheng, Godwin Norense Osarumwense Asemota, Jean De Dieu Niyonteze, Walter Nsengiyumva, Aphrodis Nduwamungu, Samuel Bimenyimana

“…Heavy usage of conventional power has led to the depletion of fossil fuels. At the same time, it has highlighted its unfriendly relationship with the environment because of carbon dioxide (CO2) emission, which is a major cause of global warming. …”
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De la neuroplasticidad a las propuestas aplicadas: estimulación temprana y su implementación en Costa Rica / From Neuroplasticity to Applied Proposals: Early Stimulation and Its Im... by Johanna Sibaja-Molina, Tracy Sánchez-Pacheco, Mijail Rojas-Carvajal, Jaime Fornaguera-Trías

“…English The discussion about environmental influence on ontogeny has fueled the question about how much context manipulation can regulate individuals’ characteristics. …”
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Bibliometric analysis and review of food waste management via sustainable approaches by U. Danya, M. Kamaraj, P. Suresh Babu, J. Aravind

“…The environmental benefits of these biorefineries are also discussed in depth, encompassing the reduction of greenhouse gas emissions, decreased reliance on fossil fuels, and the mitigation of environmental pollution. …”
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PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD) by Stefania Angelicola, Francesca Giunchi, Francesca Ruzzi, Mariateresa Frascino, Mary Pitzalis, Laura Scalambra, Maria Sofia Semprini, Olga Maria Pittino, Chiara Cappello, Irene Siracusa, Ilaria Candida Chillico, Martina Di Noia, Cristian Turato, Silvia De Siervi, Francesco Lescai, Teresa Ciavattini, Giulia Lopatriello, Luca Bertoli, Hugo De Jonge, Luisa Iamele, Annalisa Altimari, Elisa Gruppioni, Andrea Ardizzoni, Marzia Rossato, Francesco Gelsomino, Pier-Luigi Lollini, Arianna Palladini

“…Conclusions Our findings identified plasticity as a relevant hallmark of ICI-mediated HPD by demonstrating that ICIs can modulate the IFN-γ and PD-L1 pathways, driving tumor cell plasticity and fueling HPD development.…”
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Assessment of Air Pollution and Lagged Meteorological Effects in an Urban Residential Area of Kenitra City, Morocco by Mustapha Zghaid, Abdelfettah Benchrif, Mounia Tahri, Amine Arfaoui, Malika Elouardi, Mohamed Derdaki, Ali Quyou, Moulay Laarbi Ouahidi

“…In contrast, O₃ concentrations were highest during summer afternoons due to photochemical reactions fueled by strong UV radiation, while winter levels were the lowest due to reduced sunlight. …”
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Sex, Knowledge, and Attitude of Stroke Survivors Attending Bebe Herbal Center on Risk Factors before and after Stroke by Polycarp U. Nwoha, Florence O. Okoro, Emmanuel C. Nwoha, Fidelia N. Chukwu, Chidinma O. Nwoha, Nkeiru C. Ogoko, Peace N. Nwoha, Chika A. Idaguko, Augustine U. Obi, Ezenna M. Agwu, Iyanu O. Ayoola, Sunday O. Osonwa, Ifeoma H. Okpara

“…These survivors suffered mainly from hypertension, triggered by psychosocial problems and diabetes mellitus; their stroke seemed fueled by unrecognized hypertension, unrecognized diabetes mellitus, ignorance of hyperlipidemia, and wide-scale belief in witchcraft as risk factor. …”
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Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…Abstract Background The increase in opioid use disorder among young, nonurban people has fueled sharp rises in hepatitis C virus (HCV) infections. …”
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The Impact of International Tourism on Environmental Quality (Case Study: D8 Countries) by Roohollah Babaki, Behnam Elyaspour, Narges Sanjari Konarsandal

“…Therefore, it is suggested that, first, policymakers of international tourism destinations should adopt strategies that help these destinations reduce the use of fossil fuels and attract more tourism investments. Secondly, to improve environmental quality or reduce environmental degradation, instead of environmentally destructive diesel-powered transportation, tourist transportation with environmentally friendly vehicles such as electric vehicles and bicycle tourism should be selected and promoted in tourist destinations. …”
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An Areal Assessment of Subseafloor Carbon Cycling in Cold Seeps and Hydrate-Bearing Areas in the Northern South China Sea by Yanping Zhang, Min Luo, Yu Hu, Hongbin Wang, Duofu Chen

“…., cold hydrocarbon seeps) fuels the chemosynthetic biota-inhabited surface sediments and represents the major pathway to transfer carbon from sediments to the water column. …”
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CYP3A5 promotes glioblastoma stemness and chemoresistance through fine-tuning NAD+/NADH ratio by Wentao Hu, Xiaoteng Cui, Hongyu Liu, Ze Li, Xu Chen, Qixue Wang, Guolu Zhang, Er Wen, Jinxin Lan, Junyi Chen, Jialin Liu, Chunsheng Kang, Ling Chen

“…Conclusion Together, this study suggests that GSCs activate STAT3 to upregulate CYP3A5 to fine-tune NAD⁺/NADH for the enhancement of mitochondrial functions and DNA damage repair, thereby fueling tumor stemness and conferring TMZ resistance, respectively. …”
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Navigating Ethical Dilemmas Of Generative AI In Medical Writing by Qurrat Ulain Hamdan, Waleed Umar, Mahnoor Hasan

“…While this feature serves to improve the performance of these tools according to user input and requirements, it also fuels the debate about privacy breaches and cybersecurity issues that could arise if malicious forces override these tools.6 Although ChatGPT has allowed users to turn off their chat history and prevent the bot from storing their data as of April 2023, the extent to which AI-driven tools uphold the pledge of privacy and confidentiality of user data is not quite transparent. …”
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The Role of Iranians in Istanbul in Publishing and Distributing Modernist and Constitutionalist Texts by Mohammad Hossein Sadeghi, Hassan Hazrati

“…Furthermore, the study examines how Iranian authors in Istanbul influenced the development of constitutionalism in both Iran and the Ottoman Empire through their publishing endeavors.Research FindingsThis research highlights Istanbul's pivotal role in the publication and distribution of Persian texts, fueled by a new wave of Iranian immigrants arriving from the second half of the 19th/13th century. …”
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