Development of Cephradine-Loaded Gelatin/Polyvinyl Alcohol Electrospun Nanofibers for Effective Diabetic Wound Healing: In-Vitro and In-Vivo Assessments by Anam Razzaq, Zaheer Ullah Khan, Aasim Saeed, Kiramat Ali Shah, Naveed Ullah Khan, Bouzid Menaa, Haroon Iqbal, Farid Menaa

“…FTIR analyses confirmed the drug loading into BNFs. Compared to free Ceph, LNFs were significantly more thermostable and exhibited sustained/controlled Ceph release. …”
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Photoreceptor metabolic window unveils eye–body interactions by Shaopeng Yang, Zhuoyao Xin, Weijing Cheng, Pingting Zhong, Riqian Liu, Ziyu Zhu, Lisa Zhuoting Zhu, Xianwen Shang, Shida Chen, Wenyong Huang, Lei Zhang, Wei Wang

“…Here we show the ability of risk-free, in vivo photoreceptor assessment as a window into systemic health and identify shared metabolic underpinnings of photoreceptor degeneration and multisystem health outcomes. …”
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Unveiling <i>DENND2D</i> as a Novel Prognostic Biomarker for Prostate Cancer Recurrence: From Gene to Prognosis by Chi-Fen Chang, Lih-Chyang Chen, Yei-Tsung Chen, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Te-Ling Lu, Shu-Pin Huang, Bo-Ying Bao

“…<b>Results:</b> Multivariate Cox regression analyses identified <i>DENND2D</i> rs610261 G>A as significantly associated with improved BCR-free survival in both cohorts (adjusted hazard ratio = 0.39, 95% confidence interval = 0.23–0.66, <i>p</i> = 0.001). …”
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Immunogenicity in humans of a transdermal multipeptide melanoma vaccine administered with or without a TLR7 agonist by Craig L Slingluff, Gina R Petroni, Walter C Olson, Kimberly A Chianese-bullock, Donna Deacon, Mark Smolkin, William W Grosh, Max O Meneveau, Kevin T Lynch, Elise P Salerno, Elizabeth Woodson, James W Patterson

“…Ten-year overall survival was 67% and disease-free survival was 44%.Conclusions These data provide proof of principle for immunogenicity in humans of transdermal immunization using peptides in DMSO. …”
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Effect of Proteinuria Before Lenvatinib Administration on Treatment Response After Atezolizumab Bevacizumab Combination Therapy by Hironori Ochi, Masayuki Kurosaki, Takaaki Tanaka, Nobuharu Tamaki, Kaoru Tsuchiya, Yutaka Yasui, Hiroyuki Marusawa, Toshifumi Tada, Shinichiro Nakamura, Takehiro Akahane, Eisuke Okamoto, Haruhiko Kobashi, Hirotaka Arai, Michiko Nonogi, Namiki Izumi

“…The median survival time and progression free survival after administration of lenvatinib was 14.8 (95% confidence interval [CI], 11.3–18.4) and 5.5 (95% CI, 3.6–7.5) months, respectively. …”
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Identification of promising SARS-CoV-2 main protease inhibitor through molecular docking, dynamics simulation, and ADMET analysis by Ganesh Sharma, Neeraj Kumar, Chandra Shekhar Sharma, Taha Alqahtani, Yewulsew Kebede Tiruneh, Sharifa Sultana, Gabriel Vinícius Rolim Silva, Gabriela de Lima Menezes, Magdi E. A. Zaki, Jonas Ivan Nobre Oliveira

“…Molecular dynamics simulations over 300 ns confirmed the stability of the Mpro/4896 − 4038 complex of protein-ligand. Free energy landscape mapping and MM/PBSA calculations further substantiated the favorable binding and stability of the complex. …”
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Efficacy and safety of first-line nivolumab plus ipilimumab treatment in elderly patients (aged ≥ 75 years) with non-small cell lung cancer by Satoshi Endo, Hisao Imai, Atsuto Mouri, Kasumi Tsukamoto, Kenji Masaki, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Junichi Nakagawa, Kyoichi Kaira, Kunihiko Kobayashi, Hiroshi Kagamu

“…Results The overall response rate was 42.1%, the disease control rate was 73.6%, the median progression-free survival (PFS) was 7.1 months, and the median overall survival (OS) was 14.1 months. …”
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How can Blood Flow Restriction Exercise be Utilised for the Management of Persistent Pain Following Complex Injuries in Military Personnel? A Narrative Review by Luke Gray, Peter Ladlow, Russell J Coppack, Robyn P Cassidy, Lynn Kelly, Sarah Lewis, Nick Caplan, Robert Barker-Davies, Alexander N Bennett, Luke Hughes

“…Conclusion Future research needs to examine the differences in pain modulation between persistent pain and pain-free populations with BFR application, supporting the investigation of mechanisms for BFR-induced hypoalgesia, the dose-response relationship between BFR-exercise and pain modulation, and the efficacy and effectiveness of BFR application in complex musculoskeletal and persistent pain populations.…”
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Rabies vaccinations at the rural–urban divide: successes and barriers to dog rabies vaccination programs from a rural and urban campaign in Zambia by Ricky Chazya, Chilufya Aneta Susan Mulenga, Andrew D. Gibson, Frederic Lohr, Cassandra Boutelle, Sarah Bonaparte, Oline Sinywibulula, Gareth Thomas, Patricia Bwalya, George Dautu, Linous Munsimbwe, Geoffrey Muuka, Luke Gamble, Ryan M. Wallace, Michelle A. Waltenburg

“…Prioritizing vaccinations in higher-density free-roaming dog populations could maximize effectiveness in resource-limited settings. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

“…Conclusion Our results provided the first evidence that hUCMSC-migrasomes possess anti-inflammatory properties in OVA-induced allergic mice, which may provide a novel “MSC-cell free” therapeutic agent for the management of asthma.…”
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Effect of Different Concentration Methods on Quality Characteristics of Lycium chinense Juice by Jinghui LU, Jing WEN, Huining LAI, Sizhe LÜ, Yujuan XU, Yuanshan YU, Lina CHENG, Jian PENG

“…The total phenols and total flavonoids of Lycium chinense juice concentrated by VC were higher 8.76%~21.40% and 5.41%~13.77% than other groups, respectively. The DPPH free radical scavenging capacity and ferric ion reducing capacity of Lycium chinense juice concentrated by VC owed higher 6.98%~29.77% and 5.97%~26.76% when compared with the other groups, beside lower carotenoids degradation. …”
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Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort studyResearch in context by Safoora Gharibzadeh, Ash Routen, Cameron Razieh, Francesco Zaccardi, Claire Lawson, Clare Gillies, Simon Heller, Melanie Davies, Helen Atkins, Stephen C. Bain, Nazir L. Lone, Krisnah Poinasamy, Tunde Peto, Elizabeth Robertson, Bob Young, Desmond Johnston, Jennifer Quint, Jonathan Valabhji, Khalida Ismail, Michael Marks, Alex Horsley, Annemarie Docherty, Ewen Harrison, James Chalmers, Ling-Pei Ho, Betty Raman, Chris Brightling, Omer Elneima, Rachel Evans, Neil Greening, Victoria C. Harris, Linzy Houchen-Wolloff, Marco Sereno, Aarti Shikotra, Amisha Singapuri, Louise Wain, Claudia Langenberg, John Dennis, John Petrie, Naveed Sattar, Olivia Leavy, Mattew Richardson, Ruth M. Saunders, Anne McArdle, Hamish McASuley, Tom Yates, Kamlesh Khunti, C.E. Brightling, R.A. Evans, L.V. Wain, J.D. Chalmers, V.C. Harris, L.P. Ho, A. Horsley, M. Marks, K. Poinasamy, B. Raman, A. Shikotra, A. Singapuri, C.E. Brightling, R.A. Evans, L.V. Wain, R. Dowling, C. Edwardson, O. Elneima, S. Finney, N.J. Greening, B. Hargadon, V.C. Harris, L. Houchen--Wolloff, O.C. Leavy, H.J.C. McAuley, C. Overton, T. Plekhanova, R.M. Saunders, M. Sereno, A. Singapuri, A. Shikotra, C. Taylor, S. Terry, C. Tong, B. Zhao, D. Lomas, E. Sapey, C. Berry, C.E. Bolton, N. Brunskill, E.R. Chilvers, R. Djukanovic, Y. Ellis, D. Forton, N. French, J. George, N.A. Hanley, N. Hart, L. McGarvey, N. Maskell, H. McShane, M. Parkes, D. Peckham, P. Pfeffer, A. Sayer, A. Sheikh, A.A.R. Thompson, N. Williams, C.E. Brightling, W. Greenhalf, M.G. Semple, M. Ashworth, H.E. Hardwick, L. Lavelle-Langham, W. Reynolds, M. Sereno, R.M. Saunders, A. Singapuri, V. Shaw, A. Shikotra, B. Venson, L.V. Wain, A.B. Docherty, E.M. Harrison, A. Sheikh, J.K. Baillie, C.E. Brightling, L. Daines, R. Free, R.A. Evans, S. Kerr, O.C. Leavy, N.I. Lone, D. Lozano-Rojas, H.J.C. McAuley, K. Ntotsis, R. Pius, J. Quint, M. Richardson, M. Sereno, M. Thorpe, L.V. Wain, M. Halling-Brown, F. Gleeson, J. Jacob, S. Neubauer, B. Raman, S. Siddiqui, J.M. Wild, S. Aslani, G. Baxter, M. Beggs, C. Bloomfield, M.P. Cassar, A. Chiribiri, E. Cox, D.J. Cuthbertson, M. Halling-Brown, V.M. Ferreira, L. Finnigan, S. Francis, P. Jezzard, G.J. Kemp, H. Lamlum, E. Lukaschuk, C. Manisty, G.P. McCann, C. McCracken, K. McGlynn, R. Menke, C.A. Miller, A.J. Moss, T.E. Nichols, C. Nikolaidou, C. O'Brien, G. Ogbole, B. Rangelov, D.P. O'Regan, A. Pakzad, S. Piechnik, S. Plein, I. Propescu, A.A. Samat, L. Saunders, Z.B. Sanders, R. Steeds, T. Treibel, E.M. Tunnicliffe, M. Webster, J. Willoughby, J. Weir McCall, C. Xie, M. Xu, L.V. Wain, J.K. Baillie, H. Baxendale, C.E. Brightling, M. Brown, J.D. Chalmers, R.A. Evans, B. Gooptu, W. Greenhalf, H.E. Hardwick, R.G. Jenkins, D. Jones, I. Koychev, C. Langenberg, A. Lawrie, P.L. Molyneaux, A. Shikotra, J. Pearl, M. Ralser, N. Sattar, R.M. Saunders, J.T. Scott, T. Shaw, D. Thomas, D. Wilkinson, L.G. Heaney, A. De Soyza, D. Adeloye, C.E. Brightling, J.S. Brown, J. Busby, J.D. Chalmers, C. Echevarria, L. Daines, O. Elneima, R.A. Evans, J. Hurst, P. Novotny, C. Nicolaou, P. Pfeffer, K. Poinasamy, J. Quint, I. Rudan, E. Sapey, M. Shankar-Hari, A. Sheikh, S. Siddiqui, S. Walker, B. Zheng, J.R. Geddes, M. Hotopf, K. Abel, R. Ahmed, L. Allan, C. Armour, D. Baguley, D. Baldwin, C. Ballard, K. Bhui, G. Breen, K. Breeze, M. Broome, T. Brugha, E. Bullmore, D. Burn, F. Callard, J. Cavanagh, T. Chalder, D. Clark, A. David, B. Deakin, H. Dobson, B. Elliott, J. Evans, R.A. Evans, R. Francis, E. Guthrie, P. Harrison, M. Henderson, A. Hosseini, N. Huneke, M. Husain, T. Jackson, I. Jones, T. Kabir, P. Kitterick, A. Korszun, I. Koychev, J. Kwan, A. Lingford-Hughes, P. Mansoori, H. McAllister-Williams, K. McIvor, B. Michael, L. Milligan, R. Morriss, E. Mukaetova-Ladinska, K. Munro, A. Nevado-Holgado, T. Nicholson, C. Nicolaou, S. Paddick, C. Pariante, J. Pimm, K. Saunders, M. Sharpe, G. Simons, J.P. Taylor, R. Upthegrove, S. Wessely, G.P. McCann, S. Amoils, C. Antoniades, A. Banerjee, A. Bularga, C. Berry, P. Chowienczyk, J.P. Greenwood, A.D. Hughes, K. Khunti, C. Lawson, N.L. Mills, A.J. Moss, S. Neubauer, B. Raman, A.N. Sattar, C.L. Sudlow, M. Toshner, P.J.M. Openshaw, D. Altmann, J.K. Baillie, R. Batterham, H. Baxendale, N. Bishop, C.E. Brightling, P.C. Calder, C.M. Efstathiou, R.A. Evans, J.L. Heeney, T. Hussell, P. Klenerman, F. Liew, J.M. Lord, P. Moss, S.L. Rowland-Jones, W. Schwaeble, M.G. Semple, R.S. Thwaites, L. Turtle, L.V. Wain, S. Walmsley, D. Wraith, M.J. Rowland, A. Rostron, J.K. Baillie, B. Connolly, A.B. Docherty, N.I. Lone, D.F. McAuley, D. Parekh, A. Rostron, J. Simpson, C. Summers, R.G. Jenkins, J. Porter, R.J. Allen, R. Aul, J.K. Baillie, S. Barratt, P. Beirne, J. Blaikley, R.C. Chambers, N. Chaudhuri, C. Coleman, E. Denneny, L. Fabbri, P.M. George, M. Gibbons, F. Gleeson, B. Gooptu, B. Guillen Guio, I. Hall, N.A. Hanley, L.P. Ho, E. Hufton, J. Jacob, I. Jarrold, G. Jenkins, S. Johnson, M.G. Jones, S. Jones, F. Khan, P. Mehta, J. Mitchell, P.L. Molyneaux, J.E. Pearl, K. Piper Hanley, K. Poinasamy, J. Quint, D. Parekh, P. Rivera-Ortega, L.C. Saunders, M.G. Semple, J. Simpson, D. Smith, M. Spears, L.G. Spencer, S. Stanel, I. Stewart, A.A.R. Thompson, D. Thickett, R. Thwaites, L.V. Wain, S. Walker, S. Walsh, J.M. Wild, D.G. Wootton, L. Wright, S. Heller, M.J. Davies, H. Atkins, S. Bain, J. Dennis, K. Ismail, D. Johnston, P. Kar, K. Khunti, C. Langenberg, P. McArdle, A. McGovern, T. Peto, J. Petrie, E. Robertson, N. Sattar, K. Shah, J. Valabhji, B. Young, L.S. Howard, Mark Toshner, C. Berry, P. Chowienczyk, A. Lawrie, O.C. Leavy, J. Mitchell, J. Newman, L. Price, J. Quint, A. Reddy, J. Rossdale, N. Sattar, C. Sudlow, A.A.R. Thompson, J.M. Wild, M. Wilkins, S.J. Singh, W.D.-C. Man, J.M. Lord, N.J. Greening, T. Chalder, J.T. Scott, N. Armstrong, E. Baldry, M. Baldwin, N. Basu, M. Beadsworth, L. Bishop, C.E. Bolton, A. Briggs, M. Buch, G. Carson, J. Cavanagh, H. Chinoy, C. Dawson, E. Daynes, S. Defres, R.A. Evans, L. Gardiner, P. Greenhaff, S. Greenwood, M. Harvie, L. HOuchen-Wolloff, M. Husain, S. MacDonald, A. McArdle, H.J.C. McAuley, A. McMahon, M. McNarry, G. Mills, C. Nolan, K. O'Donnell, D. Parekh, Pimm, J. Sargent, L. Sigfrid, M. Steiner, D. Stensel, A.L. Tan, I. Vogiatzis, J. Whitney, D. Wilkinson, D. Wilson, M. Witham, D.G. Wootton, T. Yates, D. Thomas, N. Brunskill, S. Francis, S. Greenwood, C. Laing, K. Bramham, P. Chowdhury, A. Frankel, L. Lightstone, S. McAdoo, K. McCafferty, M. Ostermann, N. Selby, C. Sharpe, M. Willicombe, L. Houchen-Wolloff, J. Bunker, R. Gill, C. Hastie, R. Nathu, N. Rogers, N. Smith, A. Shaw, L. Armstrong, B. Hairsine, H. Henson, C. Kurasz, L. Shenton, S. Fairbairn, A. Dell, N. Hawkings, J. Haworth, M. Hoare, A. Lucey, V. Lewis, G. Mallison, H. Nassa, C. Pennington, A. Price, C. Price, A. Storrie, G. Willis, S. Young, P. Pfeffer, K. Chong-James, C. David, W.Y. James, C. Manisty, A. Martineau, O. Zongo, A. Sanderson, L.G. Heaney, C. Armour, V. Brown, T. Craig, S. Drain, B. King, N. Magee, D. McAulay, E. Major, L. McGarvey, J. McGinness, R. Stone, A. Haggar, A. Bolger, F. Davies, J. Lewis, A. Lloyd, R. Manley, E. McIvor, D. Menzies, K. Roberts, W. Saxon, D. Southern, C. Subbe, V. Whitehead, H. El-Taweel, J. Dawson, L. Robinson, D. Saralaya, L. Brear, K. Regan, K. Storton, J. Fuld, A. Bermperi, I. Cruz, K. Dempsey, A. Elmer, H. Jones, S. Jose, S. Marciniak, M. Parkes, C. Ribeiro, J. Taylor, M. Toshner, L. Watson, J. Weir McCall, J. Worsley, R. Sabit, L. Broad, A. Buttress, T. Evans, M. Haynes, L. Jones, L. Knibbs, A. McQueen, C. Oliver, K. Paradowski, J. Williams, E. Harris, C. Sampson, C. Lynch, E. Davies, C. Evenden, A. Hancock, K. Hancock, M. Rees, L. Roche, N. Stroud, T. Thomas-Woods, M. Babores, J. Bradley-Potts, M. Holland, N. Keenan, S. Shashaa, H. Wassall, E. Beranova, H. Weston, T. Cosier, L. Austin, J. Deery, T. Hazelton, C. Price, H. Ramos, R. Solly, S. Turney, L. Pearce, W. McCormick, S. Pugmire, W. Stoker, A. Wilson, N. Hart, L.A. Aguilar Jimenez, G. Arbane, S. Betts, K. Bisnauthsing, A. Dewar, P. Chowdhury, A. Chiribiri, A. Dewar, G. Kaltsakas, H. Kerslake, M.M. Magtoto, P. Marino, L.M. Martinez, C. O'Brien, M. Ostermann, J. Rossdale, T.S. Solano, E. Wynn, N. Williams, W. Storrar, M. Alvarez Corral, A. Arias, E. Bevan, D. Griffin, J. Martin, J. Owen, S. Payne, A. Prabhu, A. Reed, C. Wrey Brown, C. Lawson, T. Burdett, J. Featherstone, A. Layton, C. Mills, L. Stephenson, N. Easom, P. Atkin, K. Brindle, M.G. Crooks, K. Drury, R. Flockton, L. Holdsworth, A. Richards, D.L. Sykes, S. Thackray-Nocera, C. Wright, K.E. Lewis, A. Mohamed, G. Ross, S. Coetzee, K. Davies, R. Hughes, R. Loosley, L. O'Brien, Z. Omar, H. McGuinness, E. Perkins, J. Phipps, A. Taylor, H. Tench, R. Wolf-Roberts, L.S. Howard, O. Kon, D.C. Thomas, S. Anifowose, L. Burden, E. Calvelo, B. Card, C. Carr, E.R. Chilvers, D. Copeland, P. Cullinan, P. Daly, C.M. Efstathiou, L. Evison, T. Fayzan, H. Gordon, S. Haq, R.G. Jenkins, C. King, F. Liew, K. March, M. Mariveles, L. McLeavey, N. Mohamed, S. Moriera, U. Munawar, J. Nunag, U. Nwanguma, L. Orriss-Dib, D.P. O'Regan, A. Ross, M. Roy, E. Russell, K. Samuel, J. Schronce, N. Simpson, L. Tarusan, C. Wood, N. Yasmin, R. Reddy, A.-M. Guerdette, M. Hewitt, K. Warwick, S. White, A.M. Shah, C.J. Jolley, O. Adeyemi, R. Adrego, H. Assefa-Kebede, J. Breeze, M. Brown, S. Byrne, T. Chalder, A. Chiribiri, P. Dulawan, N. Hart, A. Hayday, A. Hoare, A. Knighton, M. Malim, C. O'Brien, S. Patale, I. Peralta, N. Powell, A. Ramos, K. Shevket, F. Speranza, A. Te, P. Beirne, A. Ashworth, J. Clarke, C. Coupland, M. Dalton, E. Wade, C. Favager, J. Greenwood, J. Glossop, L. Hall, T. Hardy, A. Humphries, J. Murira, D. Peckham, S. Plein, J. Rangeley, G. Saalmink, A.L. Tan, B. Whittam, N. Window, J. Woods, G. Coakley, D.G. Wootton, L. Turtle, L. Allerton, M. Beadsworth, A. Berridge, J. Brown, S. Cooper, A. Cross, D.J. Cuthbertson, S. Defres, S.L. Dobson, J. Earley, N. French, W. Greenhalf, H.E. Hardwick, K. Hainey, J. Hawkes, V. Highett, S. Kaprowska, G.J. Kemp, A.L. Key, S. Koprowska, L. Lavelle-Langham, N. Lewis-Burke, G. Madzamba, F. Malein, S. Marsh, C. Mears, L. Melling, M.J. Noonan, L. Poll, J. Pratt, E. Richardson, A. Rowe, M.G. Semple, V. Shaw, K.A. Tripp, B. Vinson, L.O. Wajero, S.A. Williams-Howard, J. Wyles, S.N. Diwanji, P. Papineni, S. Gurram, S. Quaid, G.F. Tiongson, E. Watson, B. Al-Sheklly, A. Horsley, C. Avram, P. Barran, J. Blaikely, M. Buch, N. Choudhury, D. Faluyi, T. Felton, T. Gorsuch, N.A. Hanley, T. Hussell, Z. Kausar, C.A. Miller, N. Odell, R. Osbourne, K. Piper Hanley, K. Radhakrishnan, S. Stockdale, D. Trivedi, A. De Soyza, C. Echevarria, A. Ayoub, J. Brown, G. Burns, G. Davies, H. Fisher, C. Francis, A. Greenhalgh, P. Hogarth, J. Hughes, K. Jiwa, G. Jones, G. MacGowan, D. Price, A. Sayer, J. Simpson, H. Tedd, S. Thomas, S. West, M. Witham, S. Wright, A. Young, M.J. McMahon, P. Neill, D. Anderson, H. Bayes, C. Berry, D. Grieve, I.B. McInnes, N. Basu, A. Brown, A. Dougherty, K. Fallon, L. Gilmour, K. Mangion, A. Morrow, K. Scott, R. Sykes, R. Touyz, E.K. Sage, F. Barrett, A. Donaldson, M. Patel, D. Bell, A. Brown, M. Brown, R. Hamil, K. Leitch, L. Macliver, J. Quigley, A. Smith, B. Welsh, G. Choudhury, J.K. Baillie, S. Clohisey, A. Deans, A.B. Docherty, J. Furniss, E.M. Harrison, S. Kelly, N.I. Lone, D.E. Newby, A. Sheikh, J.D. Chalmers, D. Connell, A. Elliott, C. Deas, J. George, S. Mohammed, J. Rowland, A.R. Solstice, D. Sutherland, C.J. Tee, N. Maskell, D. Arnold, S. Barrett, H. Adamali, A. Dipper, S. Dunn, A. Morley, L. Morrison, L. Stadon, S. Waterson, H. Welch, B. Jayaraman, T. Light, C.E. Bolton, P. Almeida, J. Bonnington, M. Chrystal, E. Cox, C. Dupont, S. Francis, P. Greenhaff, A. Gupta, L. Howard, W. Jang, S. Linford, L. Matthews, R. Needham, A. Nikolaidis, S. Prosper, K. Shaw, A.K. Thomas, L.P. Ho, N.M. Rahman, M. Ainsworth, A. Alamoudi, M. Beggs, A. Bates, A. Bloss, A. Burns, P. Carter, M. Cassar, K.M. Channon, J. Chen, F. Conneh, T. Dong, R.I. Evans, E. Fraser, X. Fu, J.R. Geddes, F. Gleeson, P. Harrison, M. Havinden-Williams, P. Jezzard, N. Kanellakis, I. Koychev, P. Kurupati, X. Li, E. Lukaschuk, K. McGlynn, H. McShane, C. Megson, K. Motohashi, S. Neubauer, D. Nicoll, G. Ogg, E. Pacpaco, M. Pavlides, Y. Peng, N. Petousi, J. Propescu, N. Rahman, B. Raman, M.J. Rowland, K. Saunders, M. Sharpe, N. Talbot, E. Tunnicliffe, W.D.-C. Man, B. Patel, R.E. Barker, D. Cristiano, N. Dormand, M. Gummadi, S. Kon, K. Liyanage, C.M. Nolan, S. Patel, O. Polgar, P. Shah, S.J. Singh, J.A. Walsh, J. Hurst, H. Jarvis, S. Mandal, S. Ahmad, S. Brill, L. Lim, D. Matila, O. Olaosebikan, C. Singh, M. Toshner, H. Baxendale, L. Garner, C. Johnson, J. Mackie, A. Michael, J. Pack, K. Paques, H. Parfrey, J. Parmar, N. Diar Bakerly, P. Dark, D. Evans, E. Hardy, A. Harvey, D. Holgate, S. Knight, N. Mairs, N. Majeed, L. McMorrow, J. Oxton, J. Pendlebury, C. Summersgill, R. Ugwuoke, S. Whittaker, W. Matimba-Mupaya, S. Strong-Sheldrake, S.L. Rowland-Jones, A.A.R. Thompson, J. Bagshaw, M. Begum, K. Birchall, R. Butcher, H. Carborn, F. Chan, K. Chapman, Y. Cheng, L. Chetham, C. Clark, Z. Coburn, J. Cole, M. Dixon, A. Fairman, J. Finnigan, L. Finnigan, H. Foot, D. Foote, A. Ford, R. Gregory, K. Harrington, L. Haslam, L. Hesselden, J. Hockridge, A. Holbourn, B. Holroyd-Hind, L. Holt, A. Howell, E. Hurditch, F. Ilyas, C. Jarman, A. Lawrie, E. Lee, J.-H. Lee, R. Lenagh, A. Lye, I. Macharia, M. Marshall, A. Mbuyisa, J. McNeill, S. Megson, J. Meiring, L. Milner, S. Misra, H. Newell, T. Newman, C. Norman, L. Nwafor, D. Pattenadk, M. Plowright, J. Porter, P. Ravencroft, C. Roddis, J. Rodger, P. Saunders, J. Sidebottom, J. Smith, L. Smith, N. Steele, G. Stephens, R. Stimpson, B. Thamu, N. Tinker, K. Turner, H. Turton, P. Wade, S. Walker, J. Watson, J.M. Wild, I. Wilson, A. Zawia, R. Aul, M. Ali, A. Dunleavy, D. Forton, N. Msimanga, M. Mencias, T. Samakomva, S. Siddique, J. Teixeira, V. Tavoukjian, J. Hutchinson, L. Allsop, K. Bennett, P. Buckley, M. Flynn, M. Gill, C. Goodwin, M. Greatorex, H. Gregory, C. Heeley, L. Holloway, M. Holmes, J. Kirk, W. Lovegrove, T.A. Sewell, S. Shelton, D. Sissons, K. Slack, S. Smith, D. Sowter, S. Turner, V. Whitworth, I. Wynter, L. Warburton, S. Painter, J. Tomlinson, C. Vickers, T. Wainwright, D. Redwood, J. Tilley, S. Palmer, G.A. Davies, L. Connor, A. Cook, T. Rees, F. Thaivalappil, C. Thomas, A. Butt, M. Coulding, H. Jones, S. Kilroy, J. McCormick, J. McIntosh, H. Savill, V. Turner, J. Vere, E. Fraile, J. Ugoji, S.S. Kon, H. Lota, G. Landers, M. Nasseri, S. Portukhay, A. Hormis, A. Daniels, J. Ingham, L. Zeidan, M. Chablani, L. Osborne, M. Marks, J.S. Brown, N. Ahwireng, B. Bang, D. Basire, R.C. Chambers, A. Checkley, R. Evans, M. Heightman, T. Hillman, J. Hurst, J. Jacob, S. Janes, R. Jastrub, M. 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Greening, K. Hadley, P. Haldar, B. Hargadon, V.C. Harris, L. Houchen-Wolloff, W. Ibrahim, L. Ingram, K. Khunti, A. Lea, D. Lee, D. Lozano-Rojas, G.P. McCann, H.J.C. McAuley, P. McCourt, T. Mcnally, G. Mills, A. Moss, W. Monteiro, K. Ntotsis, M. Pareek, S. Parker, A. Rowland, A. Prickett, I.N. Qureshi, R. Russell, N. Samani, M. Sereno, M. Sharma, A. Shikotra, S. Siddiqui, A. Singapuri, S.J. Singh, J. Skeemer, M. Soares, E. Stringer, T. Thornton, M. Tobin, E. Turner, L.V. Wain, T.J.C. Ward, F. Woodhead, J. Wormleighton, T. Yates, A. Yousuf, M.G. Jones, C. Childs, R. Djukanovic, S. Fletcher, M. Harvey, E. Marouzet, B. Marshall, R. Samuel, T. Sass, T. Wallis, H. Wheeler, R. Dharmagunawardena, E. Bright, P. Crisp, M. Stern, A. Wight, L. Bailey, A. Reddington, A. Ashish, J. Cooper, E. Robinson, A. Broadley, K. Howard, L. Barman, C. Brookes, K. Elliott, L. Griffiths, Z. Guy, D. Ionita, H. Redfearn, C. Sarginson, A. Turnbull, Y. Ellis, M. Marks, A. Briggs, K. Holmes, K. Poinasamy, S. Walker, M. Halling-Brown, G. Breen, M. Hotopf, K. Lewis, N. Williams

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Current applications and challenges in large language models for patient care: a systematic review by Felix Busch, Lena Hoffmann, Christopher Rueger, Elon HC van Dijk, Rawen Kader, Esteban Ortiz-Prado, Marcus R. Makowski, Luca Saba, Martin Hadamitzky, Jakob Nikolas Kather, Daniel Truhn, Renato Cuocolo, Lisa C. Adams, Keno K. Bressem

“…A data-driven convergent synthesis approach was applied for thematic syntheses of LLM applications and limitations using free line-by-line coding in Dedoose. Results We show that most studies investigate Generative Pre-trained Transformers (GPT)-3.5 (53.2%, n = 66 of 124 different LLMs examined) and GPT-4 (26.6%, n = 33/124) in answering medical questions, followed by patient information generation, including medical text summarization or translation, and clinical documentation. …”
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BeatProfiler: Multimodal In Vitro Analysis of Cardiac Function Enables Machine Learning Classification of Diseases and Drugs by Youngbin Kim, Kunlun Wang, Roberta I. Lock, Trevor R. Nash, Sharon Fleischer, Bryan Z. Wang, Barry M. Fine, Gordana Vunjak-Novakovic

“…We also show that our TCN-BiLSTM model was able to classify drug-free control and 4 cardiac drugs with different mechanisms of action at 96&#x0025; accuracy. …”
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Impact of Ecobiol plus ® feed additive on growth performance, physiological response, oxidative status and immunological status of Nile tilapia (Oreochromis niloticus) fingerlings... by Amira A. Omar, Doaa H. Assar, Mustafa Shukry, Aya Abo El-Ezz, Foad A. Farrag, Wesam E. Abd El-Aziz, Eman M. Moustafa

“…These results suggest that Ecobiol plus® can be a natural, antibiotic-free additive to strengthen growth and disease resistance in Nile tilapia. …”
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Parameter Study on Ultraviolet Rayleigh–Brillouin Doppler Lidar with Dual-Pass Dual Fabry–Perot Interferometer for Accurately Measuring Near-Surface to Lower Stratospheric Wind Fie... by Fahua Shen, Zhifeng Shu, Jihui Dong, Guohua Jin, Liangliang Yang, Zhou Hui, Hua Xu

“…Combining the wind speed measurement error and measurement bias on both sides, the parameters of the dual-pass dual-FPI are optimized. The free spectral range (FSR) of the dual-pass dual-FPI is selected as 12 GHz, the bandwidth as 1.8 GHz, and the peak-to-peak spacing as 6 GHz. …”
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Evaluating reproduction traits in a crossbreeding program between indigenous and exotic sheep in semi-arid lands by E. Oyieng, J.M.K. Ojango, M. Gauly, R. Mrode, R. Dooso, A.M. Okeyo, C. Kalinda, S. König

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Seasonal Mathematical Model of Salmonellosis Transmission and the Role of Contaminated Environments and Food Products by Mohammed H. Alharbi, Fawaz K. Alalhareth, Mahmoud A. Ibrahim

“…When <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi mathvariant="script">R</mi><mn>0</mn></msub></semantics></math></inline-formula> is less than 1, the disease-free equilibrium is stable, resulting in the extinction of the disease. …”
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The association between the interval from biopsy to radical prostatectomy and biochemical recurrence in patients with intermediate- and high-risk prostate cancer by Carolin Siech, Mike Wenzel, Georgina Knoblich, Cristina Cano Garcia, Clara Humke, Felix Preisser, Miriam Traumann, Luis A. Kluth, Felix K. H. Chun, Philipp Mandel, Philipp Mandel

“…In survival analyses, three-year BCR-free survival rates were 82 vs. 88% in intermediate-risk (p=0.5) and 76 vs. 75% in high-risk patients (p=1). …”
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Exploring the expression of DLL3 in gastroenteropancreatic neuroendocrine neoplasms and its potential diagnostic value by L. Yin, R. Wang, X. Ma, K. Jiang, Y. Hu, X. Zhao, L. Zhang, Z. Wang, T. Long, M. Lu, J. Li, Y. Sun

“…It was not correlated with progression-free survival (PFS) or overall survival(OS), regardless of cutoff value (1%, 50%, 75%). …”
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