CHANGE IN TESTOSTERONE LEVELS IN ENDOSCOPIC OPERATIONS ON THE PROSTATE GLAND by E. A. Efremov, S. Yu. Shekhovtsov, D. S. Merinov, A. O. Butov, Yu. V. Kastrikin, T. I. Garaev

“…In addition to standard general clinical examinations, all patients had a blood test for total testosterone, luteinizing hormone, sex hormone binding globulin. The level of free testosterone was calculated from the nomogram of Vermeulen, also testing was carried out using questionnaires AMS and IIEF-5.Results. …”
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Distinct lipidomic profiles but similar improvements in aerobic capacity following sprint interval training versus moderate-intensity continuous training in male adolescents by Wantang Su, Jianming Liu, Jianming Liu, Aozhe Wang, Haifeng Zhang, Yaqi Sun, Zhiyi Yan, Michael Svensson, Ji-Guo Yu, Li Zhao

“…In SIT, all 5 lipids, which were free fatty acid (FFA), decreased.ConclusionAlthough both MICT and SIT induced similar and significant improvements in VO2peak, serum lipid adaptations to the training differed. …”
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Inhibitory effect of coriander (Coriandrum sativum L.) extract marinades on the formation of polycyclic aromatic hydrocarbons in roasted duck wings by Yajie Yu, Yiqun Cheng, Chong Wang, Suhong Huang, Yang Lei, Ming Huang, Xibin Zhang

“…The electron spin resonance study indicated a significantly positive correlation between PAH8 and free radical level, suggesting the participation of radicals in PAHs formation. …”
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Uncovering molecular mechanisms of soybean response to 12C6+ heavy ion irradiation through integrated transcriptomic and metabolomic profiling by Honglei Ren, Bixian Zhang, Chunlei Zhang, Xiulin Liu, Xueyang Wang, Fengyi Zhang, Kezhen Zhao, Rongqiang Yuan, Ahmed M. Abdelghany, Sobhi F. Lamlom

“…A total of 1500 rounds of disease-free soybean seeds underwent irradiation with 270 MeV/u 12C6+ ion beams, administered at doses of 0, 120, and 150 Gy. …”
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The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection by Qingqing Chen, Haohao Wu, Xinwei Guo, Ke Gu, Wenjie Wang, Xiaochen Chen, Shengjun Ji, Hui Yang, Jiahao Zhu

“…The relationships between overall survival (OS), disease-free survival (DFS), and ∆SII were analyzed with both univariate Kaplan-Meier and multivariate Cox regression methods. …”
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CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models by Maia Cabrera, Romina Armando, Ian Czarnowski, Patricio Chinestrad, Ramiro Blanco, Alejandra Zinni, Daniel Gómez, Diego L. Mengual Gómez, Pablo Lorenzano Menna

“…ADMET studies further highlighted their strong potential as lead PKM2 inhibitors for GBM treatment.Molecular dynamics (MD) simulations and post-MD analyses, including Dynamic Cross-Correlation Maps (DCCM), Probability Density Function (PDF), and Free Energy Landscape (FEL), confirmed the stability of the protein-ligand interactions and highlighted critical residues at the dimer-dimer interface. …”
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Effects of Fermented Soybean Meal Substituting Plant Protein and Fish Meal on Growth, Flesh Quality, and Intestinal Microbiota of Largemouth Bass (Micropterus salmoides) by Beibei Guo, Lingling Huang, Xiaoqin Li, Yunfeng Chen, Tianyu Huang, Lizhou Ma, Xiangjun Leng

“…Compared with the FSM-0 group, the flesh hardness, shear force, total collagen, hot soluble collagen, and total free amino acid contents of FSM-20 group were significantly increased, and FSM-10-SM group also presented higher flesh hardness and shear force. …”
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Injectable supramolecular hydrogel co-loading abemaciclib/NLG919 for neoadjuvant immunotherapy of triple-negative breast cancer by Binyu Zhu, Ying Cai, Lingli Zhou, Lei Zhao, Jiameng Chen, Xiaoting Shan, Xujie Sun, Qian You, Xiang Gong, Wen Zhang, Helen He Zhu, Pengcheng Zhang, Yaping Li

“…This hydrogel provides a potential platform for neoadjuvant immunotherapy of triple-negative breast cancer with reduced toxicity compared with free abemaciclib.…”
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Augmentation index as a predictor of right ventricular dysfunction in coronary artery disease: a cross-sectional study by Arash Rahimi, Babak Geraiely, Hamed Vahidi, Mohammadreza Eftekhari, Ramyar Rahimi Darehbagh, Somayeh Mohammadi, Golrokh Ghaffari, Meysam Khoshavi

“…Results Patients with high AIx (> 80%, n = 53) had significantly worse RV systolic function compared to those with normal AIx (≤ 80%, n = 68), as evidenced by lower tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), RV free wall longitudinal strain (RVLS), and RV systolic velocity (RV S’) (all P < 0.05). …”
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Prognostic Value of Inflammatory and Nutritional Indicators in Non-Metastatic Soft Tissue Sarcomas by Yan Y, Zhang Y, Chen Y, Zhong G, Huang W, Zhang Y

“…Further analysis showed that SIRI and AGR have a high C-index, LR_χ 2, and − 2 log-likelihood, lower AIC and BIC, indicating a better model fit for overall survival (OS) and disease-free survival (DFS). The combination index of the SIRI+AGR+Enneking stage achieved the best accuracy (C-index: 0.751 for DFS; C-index: 0.755 for OS). …”
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Systematic Review and Network Meta-Analysis on Treating Hormone Receptor-Positive Metastatic Breast Cancer After CDK4/6 Inhibitors by Neha Pathak, Abhenil Mittal, Sudhir Kumar, Chitrakshi Nagpal, Eitan Amir, Partha Haldar, Bharath B. Gangadharaiah, Akash Kumar, Ashutosh Mishra, Atul Batra

“…We calculated the hazard ratio (HR) for progression-free survival (PFS) and overall survival (OS) using generic inverse variance and odds ratios (ORs) using the Mantel–Haenszel method for adverse events (AEs) with Review-Manager version-5.4. …”
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Thyroid Hormone Activation Regulates the Crosstalk between Breast Cancer and Mesenchymal Stem Cells by Annarita Nappi, Vittoria D’Esposito, Caterina Miro, Alessia Parascandolo, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Sepehr Torabinejad, Federica Restolfer, Maddalena Raia, Melania Murolo, Emery Di Cicco, Pietro Formisano, Monica Dentice

“…Furthermore, a surgery-free intraductal delivery model, i.e., the Mouse-INtraDuctal (MIND) injection method, was used as a tool for in vivo characterization of breast tumor formation and progression. …”
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Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013–2015) by Won Kyoung Cho, Hyo-Kyoung Nam, Jae Hyun Kim, Young-Jun Rhie, Sochung Chung, Kee-Hyoung Lee, Byung-Kyu Suh

“…Among 2679 subjects aged 10–19 years who participated in the Korea National Health and Nutrition Examination Survey VI (2013–2015), 1067 adolescents (M=559, F=508) with available data on free T4 (FT4) and thyroid-stimulating hormone (TSH) were included. …”
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Clinical analysis of molecular typing of 146 cases of endometrial carcinoma by Bo Zhang, Bo Zhang, Dan Zhou, Shuo Zhang, Jinbowen Yan, Qingwei Meng, Qiubo Lv

“…There were significant differences observed among the four TCGA types and pathological types, pathological grades, FIGO stage, lymph node metastasis, and LVSI. The progression-free survival (PFS) rates of patients with POLE hypermutation, MSI-H type, CNL type, and CNH type were 100%, 100%, 93.62%, and 73.3%, respectively. …”
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Whey Protein Hydrogels and Emulsion Gels with Anthocyanins and/or Goji Oil: Formation, Characterization and In Vitro Digestion Behavior by Abdullah S. Seddiek, Kaiwen Chen, Fanlin Zhou, Muhindo Mwizerwa Esther, Abdelaziz Elbarbary, Hazem Golshany, Angelo Uriho, Li Liang

“…Moreover, anthocyanin release, antioxidant activity, and the fatty acid composition profile were also analyzed during in vitro digestion. Soluble and free anthocyanins in the digested medium were reduced with the goji oil content but increased with the blueberry extract content. …”
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Rethinking Language by Gastor Mapunda, Tracey Costley, Hannah Gibson, Nancy Kula, Colin Reilly

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Aqueous foams in microgravity, measuring bubble sizes by Pasquet, Marina, Galvani, Nicolo, Pitois, Olivier, Cohen-Addad, Sylvie, Höhler, Reinhard, Chieco, Anthony T., Dillavou, Sam, Hanlan, Jesse M., Durian, Douglas J., Rio, Emmanuelle, Salonen, Anniina, Langevin, Dominique

“…DTS only allows the determination of an average bubble radius which is proportional to the photon transport mean free path $\ell ^*$. The relation between the measured diffuse transmitted light intensity and $\ell ^*$ previously derived for slab-shaped samples of infinite lateral extent does not apply to the cuboid geometry of the cells used in the microgravity experiment. …”
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Mouse ZGRF1 helicase facilitates DNA repair and maintains efficient fertility by Ernest Wee Kiat Lim, Smaragda Kompocholi, André Brannvoll, K. Stine V. Bagge, Jennifer R. Gruhn, Javier Martin-Gonzalez, Eliene Albers, Ian D. Hickson, Andrés López-Contreras, Michael Lisby

“…In the absence of ZGRF1, the rates of tumorigenesis and tumour-free survival in Eμ-Myc and Trp53 knockout mice remained largely unaffected. …”
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Optical Coherence Tomography Angiography to Distinguish Changes of Choroidal Neovascularization after Anti-VEGF Therapy: Monthly Loading Dose versus Pro Re Nata Regimen by Alexandra Miere, Hassiba Oubraham, Francesca Amoroso, Pauline Butori, Polina Astroz, Oudy Semoun, Elsa Bruyere, Alexandre Pedinielli, Manar Addou-Regnard, Camille Jung, Salomon Y. Cohen, Eric H. Souied

“…CNV size was measured using a free image analysis software (ImageJ, open-source imaging processing software, 2.0.0). …”
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Nutritional Innovation Using Green Seaweed (Ulva sp.) and Garlic Powder Extracts for White‐Leg Shrimp (Litopenaeus vannamei) Challenged by Vibrio harveyi by Nashwa Abdel‐Razek, Riad H. Khalil, Abeer A. M. Afifi, Afrah F. Alkhuriji, Dina M. Metwally

“…A commercial shrimp diet (36.1% protein) was enriched with 0.5, 1.0 and 2.0 g UE/kg diet and 2, 4 and 6 g GPE/kg diet, whereas the control group was free of any supplement. Health juveniles of L. vannamei (average weight 2–3 g) were distributed in 21 fiberglass reinforced plastic (FRP) tanks (500‐L capacity) at a stocking density of 300 animals/tank to represent each treatment in triplicate. …”
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