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  1. 9141

    Long-term maintenance of patient-specific characteristics in tumoroids from six cancer indications by Colin D. Paul, Chris Yankaskas, Pradip Shahi Thakuri, Brittany Balhouse, Shyanne Salen, Amber Bullock, Sylvia Beam, Anthony Chatman, Sybelle Djikeng, Xiaoyu Jenny Yang, Garrett Wong, Isha Dey, Spencer Holmes, Abigail Dockey, Lindsay Bailey-Steinitz, Lina Zheng, Weizhong Li, Vivek Chandra, Jakhan Nguyen, Jason Sharp, Erik Willems, Mark Kennedy, Matthew R. Dallas, David Kuninger

    Published 2025-01-01
    “…Here, we characterize the establishment and/or expansion of colorectal, lung, head and neck, breast, pancreas, and endometrial tumoroids using the standardized, serum-free Gibco OncoPro Tumoroid Culture Medium. Newly derived tumoroid lines (n = 20) were analyzed by targeted genomic profiling and RNA sequencing and were representative of tumor tissue samples. …”
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  2. 9142

    Determination of egg and milk allergen in food products by liquid chromatography-tandem mass spectrometry based on signature peptides and isotope-labeled internal standard by Sufang Fan, Junmei Ma, Zhuo Liu, Yawei Ning, Meicong Cao, Qiang Li, Yan Zhang

    Published 2023-05-01
    “…Linear range was in the range of 0.5–5000.0 nmol/L for egg and milk allergen in bread, cake, cookie, rice crust and wheat flour samples with free from egg and milk, the limits of detection of milk allergens and egg allergen were in the range between 0.94 mg/100 g and 56.71 mg/100 g, limits of quantification of milk allergens and egg allergen were in the range between 2.36 mg/100 g and 141.78 mg/100 g. …”
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  3. 9143

    Association between body composition indices and vascular health: a systematic review and meta-analysis by Mohammad Nikoohemmat, Amirhossein Ramezani Ahmadi, Ali Valizadeh, Seyed Mohammadmisagh Moteshakereh, Reza Yari-Boroujeni, Zahra Seifi, Majid Valizadeh, Behnaz Abiri

    Published 2025-01-01
    “…Pooled analyses revealed a positive association between fat-free mass (FFM) and carotid intima–media thickness (IMT) (effect size [ES]: 1.79, 95% CI 1.68–1.91), highlighting a relationship with arterial structure. …”
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  4. 9144

    Temperature Is a Key Factor Affecting Total Phosphorus and Total Nitrogen Concentrations in Northeastern Lakes Based on Sentinel-2 Images and Machine Learning Methods by Haoming Qin, Chong Fang, Ge Liu, Kaishan Song, Zhuoshi Li, Sijia Li, Hui Tao, Zhaojiang Yan

    Published 2025-01-01
    “…The RF algorithm was applied to all cloud-free Sentinel-2 satellite images of these typical lakes in northeastern China during the non-glacial period from 2017 to 2023, generating spatiotemporal distribution maps of TP and TN concentrations. …”
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  5. 9145

    A qualitative study of community perceptions and practices relating to blood donation in Cameroon by Solange Dabou, Wilfred Ngwa, Ngo Valery Ngo, Constantine T Asahngwa, Ghyslaine Bruna Djeunang Dongho, Regina Sinsai, Evrard Kepgang, Odette D Kibu, Ronald Mbua Gobina, Denis Alemka Foretia

    Published 2025-02-01
    “…Some people do not want to donate blood due to: (1) fear of needles, donor-site pain or possible ritualistic use of donated blood, (2) certain religious beliefs, such as those held by Jehovah’s Witnesses, (3) local and cultural beliefs, (4) the perception that blood donation is a commercial activity for many health personnel and (5) lack of transparency from health personnel. The practice of free and voluntary donation, as well as donations specifically to family and friends, was common. …”
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  6. 9146

    Potentialities and critical issues of liquid biopsy in clinical practice: An umbrella review by Nicola Veronese, Claudio Luchini, Stefano Ciriminna, Katia Spinelli, Santo Fruscione, Paola Mattiolo, Miriam Belluzzo, Veronica Messina, Lee Smith, Mario Barbagallo, Walter Mazzucco

    Published 2025-02-01
    “…We found that 75/211 had an excellent accuracy (AUC >0.90), with one comparison with an AUC equal to 1, i.e., Cell-Free Human Papillomavirus DNA (cfHPV-DNA) for HPV-positive oropharyngeal squamous cell carcinoma. …”
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  7. 9147

    SuessR: Regional corrections for the effects of anthropogenic CO2 on δ13C data from marine organisms by Casey T. Clark, Mattias R. Cape, Mark D. Shapley, Franz J. Mueter, Bruce P. Finney, Nicole Misarti

    Published 2021-08-01
    “…The Suess effect can be corrected for mathematically; however, a variety of disparate techniques are currently used, often resulting in corrections that differ substantially. SuessR is a free, user‐friendly tool that allows researchers to calculate and apply regional Suess corrections to δ13C data from marine systems using a unified approach. …”
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  8. 9148

    Large Language Model Approach for Zero-Shot Information Extraction and Clustering of Japanese Radiology Reports: Algorithm Development and Validation by Yosuke Yamagishi, Yuta Nakamura, Shouhei Hanaoka, Osamu Abe

    Published 2025-01-01
    “…Natural language processing plays a crucial role in structuring free-form radiology reports, facilitating the interpretation of textual content, and enhancing data utility through clustering techniques. …”
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  9. 9149

    Brewed for Performance: Caffeine’s Impact on Nutrition, Endurance and Strength in Sports by Michał Janiszewski, Marcin Komorowski, Rafał Kaczorowski, Jaromir Hunia, Jonasz Jurek, Alicja Kapciak, Julia Górny, Aleksandra Pelczarska, Tomasz Forenc

    Published 2025-01-01
    “…Our comprehensive review of literature indicates that caffeine typically ingested one hour before exercise in doses around 3-6 mg/kg raises metabolic rate, increases free fatty acids mobilization, extends time to exhaustion in running and cycling, improves maximal voluntary contraction and enhances high-speed muscular activity with low-load movements. …”
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  10. 9150

    Comparison of Different Invasive Devices for the Treatment of Urinary Incontinence after Radical Prostatectomy by Stefano Salciccia, Pietro Viscuso, Giulio Bevilacqua, Antonio Tufano, Paolo Casale, Ettore De Berardinis, Giovanni Battista Di Pierro, Susanna Cattarino, Alessandro Gentilucci, Francesca Lourdes Lia, Di Giulio Ivan, Davide Rosati, Francesco Del Giudice, Alessandro Sciarra, Gianna Mariotti

    Published 2022-01-01
    “…We compared the available treatment arms using standardized mean difference (SMD) and event rate (ER) for questionnaire results, number of pads/day, and percentage of pad-free patients. Evidence synthesis. 36 clinical trials were selected. …”
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  11. 9151
  12. 9152

    Socio-economic assessment of dog population management systems: a scoping review by Rabina Ghimire, Parimala Mohanty, Elly Hiby, Andrew Larkins, Andrew Larkins, Salome Dürr, Sonja Hartnack

    Published 2025-01-01
    “…IntroductionDog Population Management (DPM) systems primarily aim to reduce the free-roaming dog population, improve the health and welfare of humans and dogs, and foster their peaceful coexistence. …”
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  13. 9153

    Serum level of soluble interleukin‐2 receptor is positively correlated with metabolic tumor volume on 18F‐FDG PET/CT in newly diagnosed patients with diffuse large B‐cell lymphoma... by Hajime Senjo, Minoru Kanaya, Koh Izumiyama, Koichiro Minauchi, Kenji Hirata, Akio Mori, Makoto Saito, Masanori Tanaka, Hiroaki Iijima, Eriko Tsukamoto, Kazuo Itoh, Shuichi Ota, Masanobu Morioka, Daigo Hashimoto, Takanori Teshima, North Japan Hematology Study Group (NJHSG)

    Published 2019-03-01
    “…Each of TMTV ≥150 cm3 and sIL‐2R ≥1300 U/mL was significantly associated with worse 5‐year overall survival and event‐free survival. Importantly, each of sIL‐2R <1300 U/mL or TMTV <150 cm3 identified patients with favorable prognosis among NCCN‐IPI high‐intermediate and high‐risk group. …”
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  14. 9154

    Food groups, macronutrient intake and objective measures of total carotenoids and fatty acids in 16-to-24-year-olds following different plant-based diets compared to an omnivorous... by Synne Groufh-Jacobsen, Christel Larsson, Isabelle Mulkerrins, Dagfinn Aune, Anine Christine Medin

    Published 2025-01-01
    “…All groups exceeded recommendations for added and free sugar. Furthermore, all groups consumed <25g/d of dietary fibre, except vegans and pescatarians. …”
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  15. 9155

    Factors Responsible For School Dropout At Different Levels of Education in Selected Academic Institutions in Kisoro Municipality Southern Division Kisoro District. by Kamahoro, Phionah

    Published 2024
    “…The researcher recommends that; Governments should plan some special policies to improve female education like introducing special stipends for female students and also making education free for them. Although some countries have already taken some steps in this regard, it is important to expand it further for other countries. …”
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    Thesis
  16. 9156
  17. 9157

    CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

    Published 2025-01-01
    “…In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. …”
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  18. 9158

    A preliminary study on the prognostic significance of cysteine-rich EGF ligand domain 2 protein (CRELD2) in patients with triple negative breast cancer by Mehmet Zahid Kocak, Murat Araz, Siddika Findik, Aykut Demirkiran, Mustafa Korkmaz, Melek Karakurt Eryilmaz, Mehmet Artac

    Published 2025-01-01
    “…In the survival analysis of the non-metastatic patient group, five-year overall survival (OS) rate was 91.7% in the CRELD2-positive patient group and 91% in the negative group (P = 0.91). Median progression free survival (PFS) was 9.4 (95% confidence interval [CI]: 6.4–12.4) months in the CRELD2-positive group and 11.9 (95% CI: 8.2–18.6) months in the CRELD2-negative group (P = 0.04). …”
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  19. 9159

    Quality of life, pain, depression, fatigue and sleep in patients with remission or mild fibromyalgia: a comparison with remission or low disease activity rheumatoid arthritis and h... by Yidan Wang, Pengxiao Liu, Zihao Li, Shiya Wu, Meijuan Long, Yang Li, Juan Jiao, Zheng Xie

    Published 2025-01-01
    “…Objective To compare the severity of clinical symptoms and quality of life (QOL) in patients with remission or mild fibromyalgia (RFM) and remission or low disease activity in rheumatoid arthritis (RRA) patients and healthy controls (HCs) to investigate whether fibromyalgia in a stable stage can be disease-free. Methods This cross-sectional study evaluated a total of 266 RFM and 252 RRA patients and 50 HCs using Revised Fibromyalgia Impact Questionnaire (FIQR), Widespread Pain Index (WPI), Pain Visual Analogue Scale (VAS), Numerical Rating Scale, Multidimensional Fatigue Inventory (MFI-20), Pittsburgh Sleep Quality Index (PSQI), and Beck Depression Inventory (BDI), and Short Form-36 Health Status Questionnaire (SF-36). …”
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  20. 9160

    Bank collapse-landslide failure mechanism of typical reverse rock bank slope in Three Gorges Reservoir area by Yang LI, Hailin ZHAO, Bolin HUANG, Honglin LI, Kaikai XU

    Published 2025-01-01
    “…It provides important free-face conditions for the upper deformation body, which is the disaster acceleration inducement of reverse rock slope landslide failure. …”
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