Prognostic stratification of patients with AJCC 2018 pN1 disease in stage III oral squamous cell carcinoma by Ming-Hsien Tsai, Hui-Ching Chuang, Yu-Tsai Lin, Tai-Lin Huang, Fu-Min Fang, Hui Lu, Chih-Yen Chien

“…The patients with pT1N1 disease showed better 5-year overall survival (OS), disease specific survival (DSS), and disease free survival (DFS) than those with pT2-3N1 disease (pT1N1 vs pT2-3N1, OS: 96.4% vs 72.2%, p = 0.004; DSS: 96.4% vs 77.3%, p = 0.021; DFS: 84.6% vs 62.3%, p = 0.023). …”
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Intracellular iron accumulation throughout the progression of sepsis influences the phenotype and function of activated macrophages in renal tissue damage by Mira Hanna, Ahmed M. A. Akabawy, Mohamed Mansour Khalifa, Mohamed Mansour Khalifa, Marawan Abd Elbaset, Reda Abdelnasser Imam, Hanan Seddiek

“…Finally, early introduced therapy to target free iron during sepsis is a proposed novel solution for protecting the renal tissue from acute injury due to macrophage activation that may end up with chronic kidney injury, if not mortality.…”
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Research of temperature deformations of selflubricating tapered bearings of low-consumption rotor units by N. A. Raykovskiy, V. L. Yusha, A. V. Tretyakov, V. A. Zakharov, K. I. Kuznetsov

“…The use of self-lubricating bearing units of conical shape implemented according to the «rotaprint» lubrication scheme is promising in oil-free small-sized turbine units to provide a given resource. …”
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Real-World Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Medical Record Review in France by Huamao Mark Lin, Keith L. Davis, James A. Kaye, Katarina Luptakova, Saurabh P. Nagar, Mohamad Mohty

“…From first relapse, patients were assessed on second-/third-line treatments, progression-free survival (PFS), overall survival (OS), and healthcare utilization. …”
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OVERCOMING THE ANTINOMIES OF HUMAN EXISTENCE: ONTOLOGY OF TRICKSTER by T. V. Danylova

“…The true nature of a trickster opposes any restrictions: it is open to everything. A trickster is free to move from one pole to another, he constructs reality and plays with it metaphorically overcoming the antinomy of life and death.…”
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Role of B7‐H3 in predicting response to neoadjuvant chemotherapy in muscle‐invasive bladder cancer by Ekamjit S. Deol, Reza Nabavizadeh, Roxane R. Lavoie, Mihai G. Dumbrava, Edlira Horjeti, Prabin Thapa, John C. Cheville, Igor Frank, Fabrice Lucien

“…Cox regression showed no significant differences in recurrence‐free or cancer‐specific survival between the high and low B7‐H3 expression groups (p > 0.05). …”
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Anatomical and Functional MRI Changes after One Year of Auditory Rehabilitation with Hearing Aids by M. R. Pereira-Jorge, K. C. Andrade, F. X. Palhano-Fontes, P. R. B. Diniz, M. Sturzbecher, A. C. Santos, D. B. Araujo

“…One year after rehabilitation with HA, significant audiometric improvement was observed, especially in free-field Speech Reception Threshold (SRT) test and functional gain, a measure of HA efficiency. …”
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The molecular prognostic scoring system for normal karyotype myelodysplastic syndromes by Wei Wang, Yudi Zhang, Wenli Yang, Xiaozhen Liu, Lingxu Jiang, Wei Lang, Yingwan Luo, Xinping Zhou, Lu Wang, Li Ye, Ying Xu, Liya Ma, Hongyan Tong

“…The NK-PSS-M can reliably predict OS and leukemia-free survival (LFS). The performance of NK-PSS-M was comparable to that of the Molecular International Prognostic Scoring System (IPSS-M), and it significantly outperformed the Revised International Prognostic Scoring System for MDS (IPSS-R). …”
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Immune checkpoint inhibitors in cancer patients with autoimmune disease: Safety and efficacy by Jiayuan Le, Yuming Sun, Guangtong Deng, Yating Dian, Yanli Xie, Furong Zeng

“…However, no statistically significant differences were observed in the incidence of grade ≥3 irAEs, objective response rate (ORR), disease control rate (DCR), overall survival (OS), and progression-free survival (PFS) between the two groups. During ICIs treatment, irAEs are common among cancer patients with autoimmune diseases, but severe irAEs is relatively low. …”
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Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upr... by Hongde Li, Pengfei Rong, Xiaoqian Ma, Wei Nie, Yan Chen, Juan Zhang, Qiong Dong, Min Yang, Wei Wang

“…Together, these findings reveal the mechanisms underlying the therapeutic effects of UC-MSCs on renal fibrosis in DN and provide the evidence for DN cell-free therapy based on UC-MSCs in the future.…”
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Aberrant Expression of MicroRNA-15a and MicroRNA-16 Synergistically Associates with Tumor Progression and Prognosis in Patients with Colorectal Cancer by Guangfa Xiao, Huihuan Tang, Wei Wei, Jian Li, Liandong Ji, Jie Ge

“…Moreover, the survival analysis identified miR-15a expression, miR-16 expression, and miR-15a/miR-16 combination as independent predictors of both unfavorable overall survival and disease-free survival. Interestingly, the prognostic value of miR-15a/miR-16 combination was more significant than miR-15a or miR-16 expression alone. …”
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Prevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal by Jitendra Gautam, Rajendra Prasad Parajuli, Kishor Pandey

“…The multivariate logistic regression analysis revealed increased odds of IPIs among participants involved in agriculture [aOR: 5.37, 95% CI: (2.31 to 12.47)], those who kept free-ranging pigs and poultry [aOR: 5.22, 95% CI: (1.87 to 14.53)], those who did not use soap before eating [aOR: 9.96, 95% CI: (2.11 to 46.99)], and those who consumed raw or undercooked meat [aOR: 2.76, 95% CI: (1.08 to 7.05)] compared with others. …”
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Tunable Single-Longitudinal-Mode Thulium–Holmium Co-Doped Fiber Laser with an Ultra-Narrow Linewidth by Utilizing a Triple-Ring Passive Sub-Ring Resonator by Pengfei Wang, Fengping Yan, Qi Qin, Dandan Yang, Ting Feng, Peng Liu, Ting Li, Chenhao Yu, Xiangdong Wang, Hao Guo, Yuezhi Cai, Wenjie Ji, Youchao Jiang

“…Tunable SLM wavelength output from THDFLs with kHz linewidths can be achieved by designing the FCTR filter with an effective free-spectral range and a 3 dB bandwidth at the main resonant peak. …”
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Diagnosis and treatment of thyroblastoma: a case report and review of literature by Xiting Chen, Xiting Chen, Lijuan Xiong, Lijuan Xiong, Hongling Liu, Haoqiang Wang, Donghai Cheng, Wei Wang, Wenyuan He, Bo Xie, Juan Zhou

“…The patient’s progression-free survival (PFS) reached 15 months following the administration of BEP chemotherapy in conjunction with local radiotherapy. …”
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Myocardium Assessment by Relaxation along Fictitious Field, Extracellular Volume, Feature Tracking, and Myocardial Strain in Hypertensive Patients with Left Ventricular Hypertrophy by Seyed Amir Mirmojarabian, Eveliina Lammentausta, Esa Liukkonen, Lauri Ahvenjärvi, Juhani Junttila, Miika T. Nieminen, Timo Liimatainen

“…Up to now, only little attention has been paid to interactions between macromolecules and free water in hypertrophied myocardium. Purpose. …”
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NAPTUNE: nucleic acids and protein biomarkers testing via ultra-sensitive nucleases escalation by Tao Hu, Xinxin Ke, Yingying Yu, Hongmei Feng, Senfeng Zhang, Yinuo Cui, Boyang Zhang, Min He, Yinbing Tang, Lei Liu, Yu Lin, Quanquan Ji, Chuanxia Chen, Chunlong Xu, Chunyi Hu

“…Abstract In an era where swift and precise diagnostic capabilities are paramount, we introduce NAPTUNE (Nucleic acids and Protein Biomarkers Testing via Ultra-sensitive Nucleases Escalation), an innovative platform for the amplification-free detection of nucleic acids and protein biomarkers in less than 45 minutes. …”
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Using a clinical decision support system to reduce excess driving pressure: the ALARM trial by Ursula Burger-Klepp, Mathias Maleczek, Robin Ristl, Bettina Kroyer, Marcus Raudner, Claus G. Krenn, Roman Ullrich

“…However, there was no significant difference between groups in mechanical power, the number of ventilator-free days, or the percentage of patients showing progression to ARDS. …”
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Prediction of successful weaning from renal replacement therapy in critically ill patients based on machine learning by Qiqiang Liang, Xin Xu, Shuo Ding, Jin Wu, Man Huang

“…We evaluated RRT weaning success based on patients being free of RRT in the subsequent week and their overall survival. …”
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Gαs Protein Expression Is an Independent Predictor of Recurrence in Prostate Cancer by Lijuan Wang, Guihua Jin, Chenchen He, Xijing Guo, Xia Zhou, Meng Li, Xia Ying, Le Wang, Huili Wu, Qing Zhu

“…In multivariable Cox regression analysis, high Gαs expression and Gleason scores were independent predictors of both PSA progression-free and overall survival. Conclusions. Gαs down-expression is associated with adverse pathologic features and clinical PSA biochemical recurrence of prostate cancer. …”
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Multicomponent intervention for schoolchildren with asthma: Pilot cluster randomized controlled trial by Marina Reznik, MD, MS, Florinda Islamovic, MD, Jill S. Halterman, MD, MPH, Cheng-Shiun Leu, PhD, Jiaqing Zhang, PhD, Philip O. Ozuah, MD, PhD

“…Objective: We assessed preliminary effectiveness of a pilot multicomponent asthma intervention that includes classroom-based PA, asthma education to increase knowledge and reduce stigma, and care coordination to facilitate guideline-based care, on PA and symptom-free days (SFD) in urban, historically marginalized children with asthma. …”
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