Associations between subjective and objective measures of stress and load: an insight from 45-week prospective study in 189 elite athletes by Kristina Drole, Mojca Doupona, Kathrin Steffen, Kathrin Steffen, Aleš Jerin, Aleš Jerin, Armin Paravlic, Armin Paravlic

“…Blood samples were collected five times during the 2022/23 season to measure cortisol and the free testosterone to cortisol ratio (FTCR). We derived a “load” variable as the sum of training, competition, academic and work hours and calculated acute, chronic, and acute-to-chronic ratio variables for both load and stress. …”
Get full text

Examining the impact of probiotic Lactiplantibacillus pentosus 6MMI on inhibiting biofilm formation, adhesion, and virulence gene expression in Listeria monocytogenes ATCC 19115 by Behrooz Alizadeh Behbahani, Mostafa Rahmati-Joneidabad, Morteza Taki

“…The strain exhibited the highest resistance to nalidixic acid, with an inhibition zone measuring 15.20 mm, while it was least resistant to chloramphenicol, which had an inhibition zone of 27.30 mm. Treatment with cell-free supernatant (CFS) from Lpb. pentosus significantly reduced biofilm formation by 91.25 % and 24.50 % and diminished mature biofilm formation by 83.82 % and 21.80 % on L. monocytogenes. …”
Get full text

Analysis of influence of piston motion law on characteristics of working process of single-stage carbon dioxide compressor unit by I. P. Aistov, S. S. Busarov, I. S. Busarov, A. A. Kapelyukhovskaya, A. A. Galkova

“…The results presented in the work shows that the implementation of the carbon dioxide compression process in an oil-free low-speed stage of a reciprocating compressor with intensive external cooling can increase the refrigeration coefficient and improve the weight and size characteristics of the heat exchange and compressor equipment of vapor compression refrigeration machines. …”
Get full text

Stability of Ternary Drug–Drug–Drug Coamorphous Systems Obtained Through Mechanochemistry by Ilenia D’Abbrunzo, Elisabetta Venier, Francesca Selmin, Irena Škorić, Enrico Bernardo, Giuseppe Procida, Beatrice Perissutti

“…<b>Conclusions:</b> This study highlights the feasibility of coamorphous systems composed of multiple APIs using a simple, solvent-free grinding approach. The findings underscore the importance of molecular interactions in determining stability and recrystallization behavior, offering insights for designing robust coamorphous formulations.…”
Get full text

Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review by Ke Chen, Boyang Jiang, Boyang Jiang, Huiping Yan, Huiping Yan, Liu Yang, Liu Yang, Zheling Chen, Zheling Chen

“…In clinical use, bevacizumab has improved the overall survival (OS) and progression-free survival (PFS) of malignant solid tumors, and the safe use of bevacizumab has gradually become the mainstream direction of clinical, nursing and pharmaceutical research. …”
Get full text

MEMBATIK SEBAGAI MEDIA DALAM MENURUNKAN PERILAKU AGRESIF ANAK by Nunuk Nur Shokiyah

“…When carrying out the stages of batik, the child is able to express his desires, because the child is left free to express in accordance with the desired, this trains the child to grow his confidence, the child is also able to learn to manage the heart, be patient, painstaking, study and be responsible for the tasks given.     …”
Get full text

CTLA-4 and PD-1 Ligand Gene Expression in Epithelial Thyroid Cancers by Chiara Tuccilli, Enke Baldini, Salvatore Sorrenti, Antonio Catania, Alessandro Antonelli, Poupak Fallahi, Francesco Tartaglia, Susi Barollo, Caterina Mian, Andrea Palmieri, Giovanni Carbotta, Stefano Arcieri, Daniele Pironi, Massimo Vergine, Massimo Monti, Salvatore Ulisse

“…In addition, the increased expression of CD80 associated with longer disease-free survival in PTC. Higher expression of PD-L1 associated with the classical histological variant and with the presence of BRAFV600E mutation in PTC. …”
Get full text

Neoadjuvant chemoimmunotherapy for locally advanced squamous cell carcinoma of the head and neck: Systematic review and meta-analysis by Xiayi Zhu, Jie Qiu, Ya Zhang, Chunni Lin, Xiaohui Wang, Xiwei Shi, Siya Yang, Qiaoyan Wu, Li Cong

“…No significant differences were found in overall survival (OS) (hazard ratio: 0.85, 95 % CI: 0.77–0.93) and progression-free survival (PFS) (hazard ratio: 0.72, 95 % CI: 0.61–0.86). …”
Get full text

Therapy of genomic unstable solid tumours (WHO grade 3/4）in clinical stage III/IV using individualised neoantigen tumour peptides-INP trial (individualised neoantigen tumour peptid... by Ling Wang, Xia Chen, Juan Zhao, Jiaxi Tang, Wanyan Tang, Bin Liao, Weiqi Nian

“…Secondary endpoints are progression-free survival, objective response rate, objective duration of remission, 1-year survival rate and overall survival.Ethics and dissemination This study has received approval from the Ethics Committee of Chongqing University Cancer Hospital on 21 November 2019 (207/2019). …”
Get full text

Precision Higgs Constraints in U(1) Extensions of the Standard Model with a Light <i>Z</i>′-Boson by Zoltán Péli, Zoltán Trócsányi

“…Anomaly-free <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>U</mi><mo>(</mo><mn>1</mn><mo>)</mo></mrow></semantics></math></inline-formula> extensions of the standard model (SM) predict a new neutral gauge boson <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>Z</mi><mo>′</mo></msup></semantics></math></inline-formula>. …”
Get full text

Messaging with appeal to intrinsic or relational values shows potential to shift demand for wildlife as pets by Harry Marshall, Nigel J. Collar, Alexander C. Lees, Andrew Moss, Pramana Yuda, Stuart J. Marsden

“…Effective messaging should focus on the negative impacts of over‐exploitation on Indonesia's wildlife and/or national heritage, and on the positive aspects of sustainable captive‐bred alternatives, and be transmitted via multiple media, including local and faith leaders (choice varying geographically), to maximise outreach to the diverse bird‐keeping community. Read the free Plain Language Summary for this article on the Journal blog.…”
Get full text

Inkjet printing of metal oxide coatings for enhanced photovoltaic soiling environmental applications by E. Fares, B. Aissa, R.J. Isaifan

“…Compared with nanoparticle samples, a homogeneous crack and a defect-free layer were observed with dense nanoparticles in all mixed inks (except for aluminum oxide ink). …”
Get full text

Innovation through Wearable Sensors to Collect Real-Life Data among Pediatric Patients with Cardiometabolic Risk Factors by Kestens Yan, Barnett Tracie, Mathieu Marie-Ève, Henderson Mélanie, Bigras Jean-Luc, Thierry Benoit, Maxime St-Onge, Lambert Marie

“…Mobility, physical activity, and heart rate were measured in free-living environments during seven days. Algorithms processed data to generate spatio-behavioural indicators that fed a web-based interactive mapping application for personalised counseling. …”
Get full text

Effect of acupuncture on primary hypothyroidism and irregular menstruation in infertile women: a randomised controlled study by Eman Sedky Abdullah, Abeer Mohamed ElDeeb, Eman Ahmed Sultan, Hassan Omar Ghareib, Salwa Mostafa EL-Badry

“…BMI, waist, waist-to-stature ratio (WSR), free thyroxine (FT4), thyroid-stimulating hormone (TSH), luteinising hormone (LH), follicle-stimulating hormone (FSH), LH/FSH ratio, menstrual cycle period, and a health-related quality-of-life questionnaire (PCOSQ) were evaluated for all patients. …”
Get full text

Outcomes of Surgical Treatment of Multiple Primary Colorectal and Prostate Cancer by I. S. Ignatov, V. V. Balaban, E. A. Bezrukov, A. V. Nikishina, M. He, P. V. Tsarkov

“…No significant differences were found when comparing overall and recurrence-free survival in groups with metachronous and synchronous variants of multiple primary cancer.Conclusions. …”
Get full text

Physical, Textural, Rheological, and Sensory Characteristics of Amaranth-Based Wheat Flour Bread by Sahreen Nasir, Farhana Mehraj Allai, Murtaza Gani, Shaiq Ganaie, Khalid Gul, Aabida Jabeen, Darakshan Majeed

“…AF supplementation increased the moisture (31.06 to 33.24%), ash (0.92 to 1.51%), protein (12.17 to 13.11%), fat (2.16 to 2.77%), and crude fibre content (1.11 to 1.72%) of the bread while the nitrogen-free extract and alkali water retention capacity decreased from 52.58 to 47.65% and 136.00 to 112.02%, respectively. …”
Get full text

Exploring the antimicrobial and antioxidative potential of Leucas aspera (Willd.) link: Phytochemical screening, molecular docking, and HR-LC/MS profiling against SARS-CoV-2 protei... by Thavasiaanatham Seenivasan Shalini, Ragothaman Prathiviraj, Poomalai Senthilraja

“…Methods: The L. aspera methanolic leaf extract displayed a phenolic content of 100 µg/ml, consisting of 3.02 mg of gallic acid dry weight equivalents and a flavonoid content of 100 µg/ml with 3.35 mg quercetin equivalents per dry weight. The extract's free radical scavenging capabilities were at 150 µg/ml in DPPH, showing an 87 % effectiveness compared to the standard ascorbic acid 49 % inhibition capacity. …”
Get full text

Exploring the efficacy of fluorouracil and platinum based chemotherapy in advanced hepatocellular carcinoma to bridge the treatment gap in resource limited settings by Se Jun Park, Kabsoo Shin, In-Ho Kim, MyungAh Lee, Tae Ho Hong, Hyunho Kim

“…The Kaplan-Meier method determined median progression-free survival (PFS) and overall survival (OS). From April 2009 to October 2023, 48 patients with advanced HCC were included in the study. …”
Get full text

Exploring Systemic Autoimmunity in Thyroid Disease Subjects by Thushani Siriwardhane, Karthik Krishna, Vinodh Ranganathan, Vasanth Jayaraman, Tianhao Wang, Kang Bei, John J. Rajasekaran, Hari Krishnamurthy

“…We evaluated thyroid hormones, thyroid-stimulating hormone (TSH), free thyroxine (FT4), thyroid autoantibodies, anti-thyroperoxidase (anti-TPO), and anti-thyroglobulin (Tg) to comprehend the association with systemic autoimmune autoantibodies, anti-nuclear antibodies (ANA), and autoantibodies to extractable nuclear antigens (ENA) in subjects with thyroid-related symptoms. …”
Get full text

Ultrahigh piezoelectric performances of (K,Na)NbO3 based ceramics enabled by structural flexibility and grain orientation by Li-Feng Zhu, Dong Liu, Xiaoming Shi, Shiqing Deng, Jiecheng Liu, Li-Yu Wei, Zi-Qi Yang, Qi Wang, Bo-Ping Zhang, Houbing Huang, Shujun Zhang, Jing-Feng Li

“…Abstract (K,Na)NbO3-based ceramics are deemed among the most promising lead-free piezoelectric materials, though their overall piezoelectric performance still lags behind the mainstream lead-containing counterparts. …”
Get full text