Charlson syndrome index predicted survival in pancreatic cancer patients received immunotherapy by Nan Zhang, Nan Zhang, Shiyun Chen, Yue Shi, Zhikuan Wang, Ru Jia, Guanghai Dai, Guanghai Dai

“…The statistical analysis focused on examining the correlation between CCI score and survival outcome.ResultsThe high CCI group exhibited significantly lower overall survival (OS) and progression-free survival (PFS) compared to the low CCI group (p<0.05). …”
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Chasing the Beginning of Reionization in the JWST Era by Christopher Cain, Garett Lopez, Anson D’Aloisio, Julian B. Muñoz, Rolf A. Jansen, Rogier A. Windhorst, Nakul Gangolli

“…We study how these models compare to recent measurements of the Ly α forest opacity, mean free path, intergalactic medium thermal history, visibility of z  > 8 Ly α emitters, and the patchy kSZ signal from the cosmic microwave background (CMB). …”
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Human development III: Bridging Brain-Mind and Body-Mind. Introduction to “Deep” (Fractal, Poly-Ray) Cosmology by Søren Ventegodt, Tyge Dahl Hermansen, Erik Rald, Trine Flensborg-Madsen, Maj Lyck Nielsen, Birgitte Clausen, Joav Merrick

“…Only by merging brain-mind and body-mind will we be whole and free and truly ourselves. We need to develop our mental understanding, deepen our cosmology, and develop our sexuality and body-mind in order to make them meet and merge. …”
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Highly printable, strong, and ductile ordered intermetallic alloy by Yinghao Zhou, Weicheng Xiao, Dawei Wang, Xu Tang, Zheling Shen, Weipeng Li, Jun Zhang, Shijun Zhao, Junhua Luan, Zibing An, Rongpei Shi, Ming Yan, Xiaodong. Han, C. T. Liu, Yilu Zhao, Tao Yang

“…The developed CCIMA exhibits good printability, enabling a crack-free microstructure with a low porosity of 0.005%. …”
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The Impact of Surgery Delay on Early-Stage Ovarian Cancer by Dimitrios Zouzoulas, Dimitrios Tsolakidis, Iliana Sofianou, Tilemachos Karalis, Michalis Aristotelidis, Panagiotis Tzitzis, Evangelia Deligeoroglou, Maria Topalidou, Eleni Timotheadou, Grigoris Grimbizis

“…Furthermore, no differences were presented in the post-operative complications rate, hospital stay, ICU admittance, or in disease-free (<i>p</i> = 0.48) and overall survival rates (<i>p</i> = 0.703). (4) Conclusions: Suspicious adnexal masses should undergo careful differential diagnosis to avoid delays in the “wait and see” period when the final diagnosis is positive for malignancy. …”
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Longitudinal assessment of thyroid function in dogs with hypoadrenocorticism: Clinical outcomes and prevalence of autoantibodies by Nadja S. Sieber‐Ruckstuhl, Barbara Riond, Federico Fracassi, Claudia Kuemmerle‐Fraune, Solène Meunier, Regina Hofmann‐Lehmann, Claudia E. Reusch, Claudia Mueller, Natalie Hofer‐Inteeworn, Felicitas S. Boretti

“…Methods Measurement of canine thyroid stimulating hormone (cTSH), total thyroxine (T4), free thyroxine, and autoantibodies against thyroglobulin, T4, and total triiodothyronine. …”
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Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis by Xiaojun Yang, Yihong Zeng, Qinquan Tan, Zhihua Huang, Jun Jia, Guanming Jiang

“…The meta-analysis assessed overall survival (OS) and progression-free survival (PFS) of the PD-1/PD-L1 inhibitors axis and its relationship with pathological type, drug modality, and the treatment line number in patients with BM from lung cancer. …”
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The potential of gardening and other plant‐related interventions to reduce symptoms of depression: A systematic review of non‐randomized controlled trials and uncontrolled studies... by Claudio D. Rosa, Talisson S. Chaves, Silvia Collado, Lincoln R. Larson, KangJae Jerry Lee, Christiana C. Profice

“…More research is needed to understand how specific participant and intervention characteristics can influence the success of horticultural interventions on depressive symptoms. Read the free Plain Language Summary for this article on the Journal blog.…”
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The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer by Yu Chen, Facai Cui, Xiaoyu Wu, Weifeng Zhao, Qingxin Xia

“…Furthermore, the overall survival (OS) and disease-free survival (DFS) of CC patients in the high DLEU1 expression group were markedly lower than those in the low DLEU1 expression group (both p < .01). …”
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Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection by Amanda R. Loehr, Dennis M. Timmerman, Michelle Liu, Ad J. M. Gillis, Melia Matthews, Jordana C. Bloom, Peter K. Nicholls, David C. Page, Andrew D. Miller, Leendert H. J. Looijenga, Robert S. Weiss

“…Here, we report that miRNAs in the mouse miR-290-295 cluster, homologs of the human miR-371-373 cluster, were detectable in serum from mice with malignant TGCTs but not from tumor-free control mice or mice with benign teratomas. miR-291-293 were expressed and secreted specifically by pluripotent EC cells, and expression was lost following differentiation induced by the drug thioridazine. …”
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Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis by Yinan Yao, Ming Yue, Jie Wang, Hongbo Chen, Mei Liu, Feng Zang, Jun Li, Yun Zhang, Peng Huang, Rongbin Yu

“…It is urgent for patients with hepatitis C virus (HCV) infection to find a safe, effective, and interferon-free regimen to optimize therapy. A comprehensive analysis was performed to evaluate the efficacy and safety of the grazoprevir combined with elbasvir, with or without ribavirin (RBV), in 777 treatment-naive and treatment-experienced patients with HCV genotype 1 infection from 3 randomized controlled trials (RCTs). …”
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SARS-CoV2 pneumonia patients admitted to the ICU: Analysis according to clinical and biological parameters and the extent of lung parenchymal lesions on chest CT scan, a monocentri... by Abed Al Hadi Krisht, Kévin Grapin, Romain Chauvot de Beauchene, Benjamin Bonnet, Lucie Cassagnes, Bertrand Evrard, Mireille Adda, Bertrand Souweine, Claire Dupuis

“…The extent of lung parenchymal lesions was associated with a decrease in the PaO2/FiO2 ratio(p<0.01), fewer ventilatory-free days (p = 0.03), and a higher death rate at day 60(p = 0.01). …”
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Evaluation of the Single-component Thermal Dust Emission Model in Cosmic Microwave Background Experiments by Hao Liu, Jia-Rui Li, Yi-Fu Cai

“…Upon the former, previous works usually depend on a more complicated model to improve the single-component dust emission; however, our method is free from any additional model, and is sensitive enough to directly discover a substantial discrepancy between the Planck High Frequency Instrument data (100–857 GHz) and associated single-component dust emission estimations. …”
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Is <i>Punica granatum</i> Efficient Against Sepsis? A Comparative Study of Amifostine Versus Pomegranate by Kazim Sahin, Sena Sahin Aktura, Ilkay Bahceci, Tolga Mercantepe, Levent Tumkaya, Atilla Topcu, Filiz Mercantepe, Omer Faruk Duran, Huseyin Avni Uydu, Zihni Acar Yazici

“…<i>Punica granatum</i> (pomegranate) is rich in polyphenols and demonstrates strong antioxidant activity, while amifostine acts as a free radical scavenger. This study aimed to investigate the antioxidant and anti-inflammatory effects of <i>P. granatum</i> peel extract (PGPE) and amifostine in sepsis-related ALI. …”
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Time to Reach Full Enteral Feeding and Its Predictors among Very Low Birth Weight Neonates Admitted in the Neonatal Intensive Care Unit: A Follow-Up Cohort Study by Belay Alemayehu Getahun, Sileshi Mulatu, Hailemariam Mekonnen Workie

“…Very low birth weight neonates delivered from pregnancy-induced hypertension-free mothers (AHR: 2.1; 95% CI: 1.12, 3.94), gestational age of ≥33 weeks (AHR: 5,; 95% CI: 2.29, 11.13), kangaroo mother care initiated (AHR: 1.4; 95% CI: 1.01, 2.00), avoiding prefeed residual aspiration (AHR: 1.42; 95% CI: 1.002–2.03), and early enteral feeding (AHR: 1.5; 95% CI: 1.03, 2.35) were significant predictors of full enteral feeding. …”
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LncRNA SNHG17 Contributes to Proliferation, Migration, and Poor Prognosis of Hepatocellular Carcinoma by Yue Luo, Junhao Lin, Jiakang Zhang, Zhenghui Song, Dayong Zheng, Fengsheng Chen, Xuefen Zhuang, Aimin Li, Xinhui Liu

“…Moreover, HCC patients with higher SNHG17 expression had a relatively poor overall survival and disease-free survival, and ERH and PDK4 also played a marked role in the prognosis of HCC. …”
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A New Strain of Preponderant Amphitriploid Carassius Clone Juvenile With Integrated Genomes Partly From White Crucian Carp (C. auratus cuvieri) Requires Low Dietary Protein by Xing Wang, Dong Han, Junyan Jin, Xiaoming Zhu, Haokun Liu, Zhimin Zhang, Yunxia Yang, Shouqi Xie

“…Low dietary protein could obtain high muscle fatty acid, free amino acid, and lipid accumulation, including whole body and muscle crude lipid, plasma total triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c). …”
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The Oil-Bearing Strata of Permian Deposits of the Ashal’cha Oil Field Depending on the Content, Composition, and Thermal Effects of Organic Matter Oxidation in the Rocks by Galina P. Kayukova, Anastasiya N. Mikhailova, Igor P. Kosachev, Dmitry A. Emelyanov, Mikhail A. Varfolomeev, Boris V. Uspensky, Alexey V. Vakhin

“…It is shown that the rocks are very heterogeneous in their mineral composition and in the content of both free hydrocarbons by extraction with organic solvents and insoluble OM closely associated with the rock. …”
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A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2– Metastatic Breast Cancer by Elizabeth J. Anderson, Lea E. Mollon, Joni L. Dean, Terri L. Warholak, Ayal Aizer, Emma A. Platt, Derek H. Tang, Lisa E. Davis

“…Recent evidence suggests combination therapy with the PI3K inhibitor (PI3Ki) alpelisib and endocrine therapy (ET) improves response rates and progression-free survival (PFS) in PIK3CA-mutant, hormone receptor positive (HR+) BC versus ET alone; thus, better understanding the clinical and epidemiologic elements of these mutations is warranted. …”
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Bubble connectivity in experimentally-sheared crystal-bearing silicic melts by Daffos, Camille, Martel, Caroline, Arbaret, Laurent, Champallier, Rémi

“…The samples were deformed in torsion at a temperature of 650 °C (crystal-free) or 750 °C (crystal-bearing), confining pressure of 50 MPa, constant moderate shear rate of $2 \times 10^{-4}~\mathrm{s}^{-1}$, and low strains ($\gamma < 2$). …”
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