A Child as a Donor for Hematopoietic Stem Cell Transplantation: Bioethical Justification—A Case Study on Sickle Cell Disease by Andrea Z. Pereira, Ricardo Hellman, Nelson Hamerschlak, Andrea Kondo, Polianna Mara Rodrigues de Souza, Wilson Leite Pedreira, Luiz Fernando Alves Lima Mantovani, Eduardo Juan Troster, Henrique Grunspun, Marco Aurélio Scarpinella Bueno

“…HSCT with cells from the bone marrow of a HLA-identical sibling used in SCD has a low mortality risk, high cure rate, and high event-free survival rate after a median follow-up of 5-6 years. …”
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Soluble RAGE Plasma Levels in Patients with Coronary Artery Disease and Peripheral Artery Disease by Colomba Falcone, Sara Bozzini, Luigina Guasti, Angela D’Angelo, Anna Clizia Capettini, Edoardo Maria Paganini, Rossana Falcone, Roberto Moia, Carmine Gazzaruso, Gabriele Pelissero

“…Clinical and laboratory parameters including the ankle brachial index (ABI) and sRAGE (enzyme-linked immunosorbent assay kit) were investigated in 544 patients with angiographically documented CAD and 328 control subjects. 213/554 CAD patients (39%) showed an ABI <0.9 associated with typical symptoms (group CAD + PAD), whereas 331 patients were free from PAD. The concentration of plasma sRAGE was significantly lower (P<0.0001) in CAD population, with and without PAD, than in control subjects. …”
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Exogenous plasmid capture to characterize tetracycline-resistance plasmids in sprouts obtained from retail in Germany by Maria Stein, Erik Brinks, Diana Habermann, Gyu-Sung Cho, Charles M. A. P. Franz

“…To capture plasmids, a plasmid-free Escherichia (E.) coli CV601 strain, containing a green fluorescent protein gene for selection, was used as the recipient strain in exogenous plasmid capture experiments. …”
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Assessment of Nutritional Status, Digestion and Absorption, and Quality of Life in Patients with Locally Advanced Pancreatic Cancer by J. E. Witvliet-van Nierop, C. M. Lochtenberg-Potjes, N. J. Wierdsma, H. J. Scheffer, G. Kazemier, K. Ottens-Oussoren, M. R. Meijerink, M. A. E. de van der Schueren

“…Sixteen patients with LAPC were prospectively assessed for weight loss (WL), body mass index (BMI), fat-free mass index (FFMI), handgrip strength (HGS), dietary macronutrient intake, serum vitamin levels, resting and total energy expenditure (REE and TEE, indirect calorimetry), intestinal absorption capacity and fecal losses (bomb calorimetry), exocrine pancreatic function (fecal elastase-1 (FE1)), and gastrointestinal quality of life (GIQLI). …”
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Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity by Alisha Karki Chhetry, Subhila Dhakal, Lalita Chaudhary, Khimdhoj Karki, Ram Bahadur Khadka, Gautam Prasad Chaudhary, Tonking Bastola, Amrit Poudel, Pramod Aryal, Jitendra Pandey

“…The in vitro 2,2′-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity showed that the methanol extract of root barks displayed the most potent antioxidant activity (IC50 : 6.1 µg/ml). …”
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Surface roughness and material removal of Si3N4 cylindrical rollers using double-side grinding with diamond film pads by Fenfen Zhou, Yongkang Jin, Qi Shao, Weifeng Yao, Hongyun Wang

“…Remarkably, this research achieved defect-free surfaces of ceramic cylindrical rollers with a minimum average roughness of 6 nm and a deviation of 2 nm. …”
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YAP1 as a Novel Negative Biomarker of Immune Checkpoint Inhibitors for EGFR-Mutant Non-Small-Cell Lung Cancer by Ling-Chen Li, Xie-Wan Chen, Ling Fang, Chun-Li Jian, Yong-Xin Yu, Xing-Yun Liao, Jian-Guo Sun

“…More importantly, it was verified that YAP1_High subpopulation had a significantly shorter progression-free survival (PFS) and overall survival (OS) after ICIs treatment in EGFR-mutant NSCLC patients in the clinical trial. …”
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Development and validation of a new reverse-phase high-performance liquid chromatography (RP-HPLC) method for the quantifications of tolperisone loaded in liposomes by Rawan N. AlKaraki, Rula R. Haddadin, Shahed K. Tarawneh, Marwa A.M. Alimari, Rehan M. Alkasasbeh, Tebat Al-ferdous E. Shamaileh, Mustafa S. Almohtaseb, Malek G. Hajaya

“…The validated RP-HPLC method was used to demonstrate the suitability of liposomes as a carrier for TOL by evaluating its entrapment efficiency (14.76 %), along with achieving a slower drug in-vitro cumulative percentage release in the targeted media (compared to free TOL solution) from the liposomes.…”
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The development of a kinetic biotic ligand model to predict acute toxicity of Gadolinium for Daphnia magna by Marion Revel, Qiao-Guo Tan, Andrew Hursthouse, Susanne Heise

“…Its acute toxicity depends on its free ion concentrations (Gd3 +), which is directly related to chemical speciation. …”
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InP/Si₃N₄ Hybrid Integrated Lasers for RF Local Oscillator Signal Generation in Satellite Payloads by Jessica César-Cuello, Alberto Zarzuelo, Robinson C. Guzmán, Charoula Mitsolidou, Ilka Visscher, Roelof B. Timens, Paulus W. L. Van Dijk, Chris G. H. Roeloffzen, Luis González, José Manuel Delgado Mendinueta, Guillermo Carpintero

“…The device provides an extensive wavelength tuning range across the entire C-band and exhibits exceptionally narrow optical linewidths, below 40 kHz in free-running mode. This results in ultra-wideband tunable RF signals with narrow electrical linewidths below 100 kHz. …”
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Distribution and clinicopathological characteristics of G-CSF expression in tumor cells and stromal cells in upper tract urothelial carcinoma by Go Kobayashi, Yohei Sekino, Hikaru Nakahara, Kohei Kobatake, Keisuke Goto, Tetsutaro Hayashi, Kazuhiro Sentani, Nobuyuki Hinata

“…Public data showed that G-CSF expression was also associated with decreased progression-free survival and disease-specific survival. A prognostic model was constructed by incorporating the presence or absence of G-CSF expression along with clinicopathologic factors, which allowed for a more accurate prediction of poor prognosis. …”
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Chemical Composition and Biological Activities of the Essential Oils of Chrysophyllum albidum G. Don (African Star Apple) by Daniel Nartey, Joseph Nana Gyesi, Lawrence Sheringham Borquaye

“…The IC50 values obtained from the hydrogen peroxide scavenging, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging, and inhibition of lipid peroxidation assays were 301.8 ± 0.7 and 669.2 ± 2.1 μg/mL, 1048.0 ± 0.3 and 1454.0 ± 0.3 μg/mL, and 460.1 ± 2.7 and 457.4 ± 0.3 μg/mL for both leaf and fruit essential oils, respectively. …”
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The effect of β-carotene supplementation above requirement on the production and reproduction performance of female sheep and goats - A mini review by Osman Ahmed, Abubeker Hassen, Khoboso Lehloenya

“…In animals, β-carotene functions mainly as pro-vitamin A and as a scavenger of free radicals, especially against singlet-state oxygen. …”
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Role of Ultrasonography in Monitoring Chemotherapeutic Effects on Primary Thyroid Lymphoma: A Single-Center Retrospective Study by Shirong Liu, Ying Fu, Ligang Cui, Shumin Wang, Shi Tan

“…The sonographic features were examined pre- and post-treatment using ultrasound (US) to monitor the treatment response at the first to second, third to fourth, and end cycles of chemotherapy and follow-up, and progression-free survival (PFS) and overall survival (OS) were analyzed. …”
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Genomic insights and comparative analysis of Colletotrichum species associated with anthracnose fruit rot and crown rot of strawberry in North Carolina by Tika B. Adhikari, Norman Muzhinji, Ashley N. Philbrick, Frank J. Louws, Frank J. Louws

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A Case Report of Bowel Perforation in a Gravid COVID-19 Patient by A. T. Guiritan, J. G. Cataluña

“…Upon opening the peritoneum, free air was evacuated. Approximately 1.4 liters of fecaloid peritoneal fluid was suctioned and adhesive band was noted at the pelvic area. …”
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General principles of combating corruption in the countries of the Visegrad Four: the experience of the Czech Republic by V. S. Makarenko, O. S. Bakumov

“…The priority areas of combating corruption, determined by the government of the Czech Republic and enshrined in the Anti-corruption agenda, have been considered, including: creation of an independent, efficient, professional, integrated and corruption-resistant state administration; transparency and efficiency of the decision-making process and the legislative process; regulation of the system of free access to information, etc. There are two groups of main state and non-state organizations in the Czech Republic whose activities are aimed at preventing and combating corruption: 1) those engaged in analytical and investigative activities; 2) those that carry out preventive, educational and coordination activities. …”
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JAUNOSIOS KARTOS KATALIKŲ INTELEKTUALŲ PAŽIŪROS Į KAPITALIZMĄ IR SOCIALIZMĄ TARPUKARIO LIETUVOJE by Valdas Pruskus

“…However, acquisition and selling of shares shall not be an obligation, but only a free and voluntary self-determination. On the other hand, an individual must feel a real support of the state as well, and it's task of paramount importance shall be a formation of the conditions for everybody and each member of the society to pursue their objects, taking into account the highest value - a human and his dignity, which cannot be sacrificed to the seeming omnipotence of the faceless machine building. …”
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Tale of two zones: investigating the clinical outcomes and research gaps in peripheral and transition zone prostate cancer through a systematic review and meta-analysis by Pedro Oliveira, Robert G Bristow, Ananya Choudhury, Ashwin Sachdeva, Noel Clarke, Hitesh Mistry, Amin Ali, Thiraviyam Elumalai, BhanuPrasad Venkatesulu, Lauren Hekman, Esther Baena

“…Primary endpoints were biochemical relapse-free survival (bRFS) and distant metastases rate; secondary endpoints included clinical and pathological features.Results Ten retrospective cohort studies were identified, six reported HRs for bRFS between PZ and TZ tumours. …”
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Isoproterenol mechanisms in inducing myocardial fibrosis and its application as an experimental model for the evaluation of therapeutic potential of phytochemicals and pharmaceutic... by Lujain Bader Eddin, Mohamed Fizur Nagoor Meeran, Niraj Kumar Jha, Samer N. Goyal, Shreesh Ojha

“…The induced oxidative stress with subsequent perturbations in cellular signaling cascades through triggering the release of free radicals is considered the initiating mechanism of myocardial fibrosis. …”
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