Harnessing silica nanoparticles grafted with ascorbic acid to alleviate oxidative stress and impaired brain activity in rats by Essia Hamdi, Slah Hidouri, Ana-Belén Muniz-Gonzalez, Marwa Kechnebbou, Salem Amara

“…The in-vitro, antioxidant assays revealed that SiO2-NPs@AA exhibited significant radical scavenging activity (DPPH and hydroxyl radicals) and high iron-chelating ability with enhanced stability compared to free ascorbic acid. Moreover, the in-vivo study demonstrated that SiO2-NPs@AA mitigated H2O2-induced effects in key enzymes, including superoxide dismutase, catalase, glutathione (GSH), and restore acetylcholinesterase (AChE) levels. …”
Get full text

Submental liposuction for the management of lymphedema following head and neck cancer treatment: a randomized controlled trial by Uthman Alamoudi, Benjamin Taylor, Colin MacKay, Matthew H. Rigby, Robert Hart, Jonathan R. B. Trites, S. Mark Taylor

“…Methods All head and neck cancer patients at an oncology center in tertiary hospital setting who complained to their attending surgeon or radiation oncologist regarding cervical lymphedema secondary to head and neck cancer treatment, and had been disease-free for a minimum of one year, with no previous facial plastic surgical procedures were eligible for inclusion into the study. …”
Get full text

Thyroid Function in Chronically Transfused Children with Beta Thalassemia Major: A Cross-Sectional Hospital Based Study by Suraj Haridas Upadya, M. S. Rukmini, Sowmya Sundararajan, B. Shantharam Baliga, Nutan Kamath

“…Thyroid dysfunction mainly occurs by gland infiltration, chronic tissue hypoxia, free radical injury, and organ siderosis. Objectives. …”
Get full text

Association between the use of mobile touchscreen devices and the quality of parent-child interaction in preschoolers by Krisztina Liszkai-Peres, Zsófia Budai, Zsófia Budai, Adrienn Kocsis, Zsolt Jurányi, Ákos Pogány, György Kampis, Ádám Miklósi, Veronika Konok

“…In this study, we applied a parental questionnaire and a behavioral observational method in a laboratory setting (free and structured play sessions) to examine the association between preschool MTSD use and the quantity and quality of parent–child relationships. …”
Get full text

Enhanced multiscale human brain imaging by semi-supervised digital staining and serial sectioning optical coherence tomography by Shiyi Cheng, Shuaibin Chang, Yunzhe Li, Anna Novoseltseva, Sunni Lin, Yicun Wu, Jiahui Zhu, Ann C. McKee, Douglas L. Rosene, Hui Wang, Irving J. Bigio, David A. Boas, Lei Tian

“…Traditional histology reveals micro- and meso-scale brain features but suffers from staining variability, tissue damage, and distortion, which impedes accurate 3D reconstructions. The emerging label-free serial sectioning optical coherence tomography (S-OCT) technique offers uniform 3D imaging capability across samples but has poor histological interpretability despite its sensitivity to cortical features. …”
Get full text

Un plomb inscrit de Saint-Couat-d’Aude (Aude) : des pérégrins sur le territoire de Narbonne by Julien Aliquot, Michel Feugère

“…Thus, they likely refer to indigenous incolae of peregrine status, i.e. free men originating from the Narbonne colony territory. …”
Get full text

In Vitro Characterization of Fluted Pumpkin Leaf Protein Hydrolysates and Ultrafiltration of Peptide Fractions: Antioxidant and Enzyme-Inhibitory Properties by Akinsola Albert Famuwagun, Adeola Monisola Alashi, Saka Olasunkanmi Gbadamosi, Kehinde Adekunbi Taiwo, Joseph Durodoluwa Oyedele, Odunayo Clement Adebooye, Rotimi Emmanuel Aluko

“…Among the fractions, the <1 and 1-3 kDa were the most effective free radical scavengers and metal chelators in addition to their strong inhibitory activities against α-amylase, α-glucosidase, and ACE. …”
Get full text

Diet Supplementation Influences Ghrelin System Expression in the Skin Appendages of the Sheep by Margherita Maranesi, Cecilia Dall’Aglio, Sara Moscatelli, Elisa Palmioli, Paola Coliolo, Daniele Marini, Gabriella Guelfi, Paola Scocco, Francesca Mercati

“…Three-year-old female sheep were free to graze from June to the pasture maximum flowering (MxF group) and from this period to maximum dryness addicted (Exp group) or not (MxD group) with 600 gr/die/head of barley and corn. …”
Get full text

Cost-Utility Analysis of Add-on Cannabidiol vs Usual Care Alone for the Treatment of Seizures in Patients With Treatment-Resistant Lennox-Gastaut Syndrome or Dravet Syndrome in the... by Jamshaed Siddiqui, Sally Bowditch

“…**Methods:** A cohort-based Markov model from a Dutch societal perspective, based on seizure frequency and seizure-free days, was developed for patients receiving CBD plus usual care (antiseizure medications, including clobazam) or usual care alone. …”
Get full text

NEGATION, INCLUDING, GRADUAL OBLIVION: STATE STRATEGIES ON SOVIET HERITAGE IN GEORGIA, ARMENIA AND AZERBAIJAN by A. A. Tokarev

“…Despite competitive elections and free media, the Armenian leadership seeks to establish a political system with a single dominant party and formally maintain electoral competition. …”
Get full text

Fish Tank Granuloma Presenting as a Nasal Cavity Mass by Motoki Sekine, Fumiyuki Goto, Kosuke Saito, Shoji Kaneda, Hikaru Yamamoto, Tomoaki Murakami, Takahide Hamano, Kenji Okami

“…Mycobacterium marinum is a free-living nontuberculous mycobacterium that is widely distributed in freshwater and seawater around the world. …”
Get full text

Development of RT-PCR Assays for Simple Detection and Identification of Sabin Virus Contaminants in the Novel Oral Poliovirus Vaccines by Olga Singh, Hasmik Manukyan, Erman Tritama, Shwu-Maan Lee, Jerry P. Weir, Majid Laassri

“…Additionally, an analysis of 12 trivalent nOPV formulation lots using both methods confirmed that the nOPV lots were free from Sabin virus contamination. Conclusions: The results demonstrated that the RT-PCR assays are sensitive and specific. …”
Get full text

Comparison of citrate dialysate in pre- and post-dilution online hemodiafiltration: effect on clot formation and adequacy of dialysis in hemodialysis patients by Pasu Nakornchai, Arisara Jitraree, Monpinya Charttong Homjan, Thanachit Laykhram, Thananda Trakarnvanich

“…Adequacy of dialysis, laboratory parameters, and quality of life were measured as secondary objectives.Results The mean clotting scores in the pre-dilution mode were significantly lower than those in the post-dilution mode and in all phases except the heparin-free phase (p < 0.001 in the baseline phase, p = 0.001 in phase 1, and p = 0.023 in phase 2). …”
Get full text

Bilosomal Co-Encapsulated Tamoxifen and Propranolol for Potentiated Anti-Breast Cancer Efficacy: In Vitro and In Vivo Investigation by Toka T. Elebyary, Amal A. Sultan, Sally E. Abu-Risha, Gamal M. El Maghraby, Manna Amin

“…<b>Methods</b>: Bilosomes comprising Span60, cholesterol, and increasing concentrations of bile salts were prepared together with bile salts containing free standard niosomes. The vesicular size and morphology were characterized. …”
Get full text

Revealing the critical state and identifying individualized dynamic network biomarker for type 2 diabetes through advanced analysis methods on individual basis by Peiyu Li, Shaowen Jing, Guo Tian, Jing Jiang

“…The three methods are data-driven and model-free on an individual basis. sJSD method is more sensitive to the critical state, while NIG and TNFE methods are more robust and effective. …”
Get full text

Organoleptic, physical, and chemical tests of artificial feed for milk fish substituted by earthworm meal (Lumbricus sp.) by Siti Aslamyah, Muh. Yusri Karim

“…The quality of feed is chemically with moisture content ranging from 8,4–9,1%, 16,7–19,46% ash, 31,07–32,37%, protein, 6,67–7,58% fat, crude fiber 7,45–7,87%, NFE (nitrogen free extracts) 35,35–35,48%. Results show that different levels of substitution of fish meal with earthworms meal (Lumbricus sp.) produces the same feed quality and contains nutrients in a range requirement milkfish. …”
Get full text

Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis by Muhammad Osama, Muhammad Haris Khan, Safeena Khan, Amna Hussain, Ammara Tahir, Mehran Ullah, Abdullah Afridi, Ubaid Ullah, Wajeeh Ur Rehman

“…The primary outcomes were progression-free survival (PFS) and minimal residual disease (MRD) status. …”
Get full text

Physiological and Biochemical Responses of Ulva prolifera and Ulva linza to Cadmium Stress by He-ping Jiang, Bing-bing Gao, Wen-hui Li, Ming Zhu, Chun-fang Zheng, Qing-song Zheng, Chang-hai Wang

“…A range of parameters (concentrations of cadmium, Ca2+, N, P, K+, Cl−, free amino acids (FAAs), proline, organic acids and soluble protein, Fv/Fm, Yield, OAA, and K+/Na+) could be used to evaluate cadmium resistance in Ulva by correlation analysis. …”
Get full text

Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC–MS/MS peptidome analysis by Vasin Thanasukarn, Piya Prajumwongs, Nattha Muangritdech, Watcharin Loilome, Nisana Namwat, Poramate Klanrit, Arporn Wangwiwatsin, Sawanya Charoenlappanit, Janthima Jaresitthikunchai, Sittiruk Roytrakul, Attapol Titapun

“…Serum samples of 81 CCA patients were analyzed using MALDI-TOF MS and LC–MS/MS, with statistical analysis correlating peptide profiles with clinical outcomes like disease-free survival (DFS) and overall survival (OS). A 365-day DFS cut-off effectively distinguished early from late recurrence, with early recurrence linked to poorer survival outcomes. …”
Get full text

Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties by Mingming Du, Dean Kavanagh, Zhibing Zhang, Neena Kalia

“…This study tested whether this could be achieved using label-free microfluidic devices. Methods. 2 straight (A-B) and 3 spiral (C-E) devices were fabricated with different dimensions. …”
Get full text