Galectin-1-Dependent Mitochondria Apoptosis Plays an Essential Role in the Potential Protein Targets of DBDCT-Induced Hepatotoxicity as Revealed by Quantitative Proteomic Analyses by Jiayu Song, Yuan Ren, Lihua Liu, Yixin Wang, Chuandao Shi, Xiaoqing Ji, Yunlan Li, Qingshan Li

“…In this study, proteomic analysis revealed that 146 proteins (98 upregulated and 48 downregulated) were differentially identified by label-free LC-MS/MS after DBDCT treatment. Meanwhile, network analysis of these differential proteins suggested that protein Galectin-1 (Gal-1) could regulate the apoptosis process (15 related proteins), which played an essential role in the potential targets of DBDCT-induced hepatotoxicity. …”
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Development of an algorithm impacting COPD care through personalized nutrition and IoT-based monitoring by Prachi Sharma, Mihir Gharia, Devina Aswal, Vishva Trivedi, Bhavnita Soni, Prerna Soni, Devesh Joshi, Dhvni Lalan, Vrushali Athavale, Irfan Shaikh, Koshy Jacob

“…Methods The study involved a sample of 10 COPD patients, evaluating key parameters such as Forced Expiratory Volume in 1 s (FEV1), Forced Vital Capacity, Weight, Body Mass Index (BMI), Fat-Free Mass Index, and Distance Covered during the 6-Minute Walk Test (6MWT) before and after the algorithm’s implementation in the MyTatva app. …”
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Listeria monocytogenes use multiple mechanisms to disseminate from the intestinal lamina propria to the mesenteric lymph nodes by Joshua S. Nowacki, Grant S. Jones, Sarah E. F. D'Orazio

“…Whole-mount fluorescent microscopy of lymphatic vessels following ligated loop infection revealed both free-floating L. monocytogenes and cell-associated bacteria within lymphatic vessels. …”
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The value of increasing sequencing depth for noninvasive prenatal screening for whole chromosomal aneuploidy by Dongmei Wang, Fangfang Guo, Yaping Hou, Haishan Peng, Tingting Hu, Jiexia Yang

“…This study recruited a cohort of 59,800 singleton pregnancies from Guangdong Women and Children Hospital between January 2015 and December 2020, including 48,018 cases of NIPT and 11,782 cases of expanded NIPT. Cell-free DNA from plasma samples was sequenced at a sequencing depth of 0.15X for NIPT and 0.4X for expanded NIPT. …”
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Ultrasound Guidance for Renal Tract Access and Dilation Reduces Radiation Exposure during Percutaneous Nephrolithotomy by Thomas Chi, Selma Masic, Jianxing Li, Manint Usawachintachit

“…All patients were rendered stone-free and no additional secondary procedures were required. …”
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Development of Homogeneous Carboxylation of Phenolates via Kolbe–Schmitt Reaction by Dmitry A. Merzliakov, Michael S. Alexeev, Maxim A. Topchiy, Dmitry G. Yakhvarov, Nikolai Yu. Kuznetsov, Anton L. Maximov, Irina P. Beletskaya

“…The use of ¹³C NMR spectroscopy enabled the observation of a “carbonate complex” in the solution for the first time, with the carbonate carbon displaying a chemical shift value of 142 ppm, an unusual finding for stable carbonates, and located between the signals of free dissolved CO₂ and carboxylate derivatives.…”
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Immobilization of Alkaline Collagenase from Bacillus subtilis onto Sulfonated Polystyrene Nanospheres for Hydrolysis of Tilapia Collagen by Ling Zhang, Xiaocui Yang, Kaijun Xiao, Yuyi Lu, Chunhai Li, Zijin Zhang

“…Under this condition, the immobilization ratio of collagenase was 73.48%, the specific activity was 274.05 U/μg, and the specific activity of the immobilized enzyme was about 53.74% that of the free enzyme. The average particle size of SPS nanospheres was 155.1 nm. …”
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Near complete genome assembly of Yadong trout (Salmo trutta) by Chen Li, Shenglei Han, Shuo Li, Kaiqiang Liu, Yuyan Liu, Hong-yan Wang, Qian Wang, Changlin Liu, Changwei Shao

“…In this assembly, a total of 12 chromosomes were assembled to a gap-free level, with 8 of them reaching the telomere-to-telomere level. …”
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DISTAL TIBIAL RECONSTRUCTION WITH INTRAMEDULLARY NAIL COMBINED WITH T-PLATE FOLLOWING EN-BLOC-EXCISION OF GIANT CELL TUMOR OF DISTAL TIBIA: CASE-REPORT by Mujaddid Idulhaq, Fajar Baskoro Gardjito, Ibnu Yudistiro

“…Discussion: The main treatment of giant cell tumor of the bone is surgical removal to achieve tumor-free by eradication of the tumor, with various surgical techniques for reconstructing the cavity left. …”
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Formation of the "Self-Made-Man" Idea in the Context of the Christian Middle Ages by V. Y. Antonova, O. M. Korkh

“…In the Middle Ages, this intention became essentially universal, as it became a right, even an obligation of every Christian to be free, at least from the worldly, in determining and realizing his own destiny. …”
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Design of polymorphic heterogeneous shell in relaxor antiferroelectrics for ultrahigh capacitive energy storage by Huifen Yu, Tengfei Hu, Haoyu Wang, He Qi, Jie Wu, Ruonan Zhang, Weisan Fang, Xiaoming Shi, Zhengqian Fu, Liang Chen, Jun Chen

“…Leveraging the core-shell effect and polarization heterogeneity, an ultrahigh recoverable energy density of 12.7 J cm-3 and an impressive efficiency of 87.2% are achieved in lead-free relaxor antiferroelectrics, making a performance breakthrough in core-shell dielectrics. …”
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Explication of Pharmacological Proficiency of Phytoconstituents from Adansonia digitata Bark: An In Vitro and In Silico Approaches by Sangavi P., Gowtham Kumar S., Nachammai KT., Chandrabose Selvaraj, Langeswaran K.

“…The results of different assays, such as α-diphenyl-β-picrylhydrazyl (DPPH), superoxide, nitric oxide scavenging assays, and total antioxidant by thiobarbituric acid method (TBA) and ferric thiocyanate (FTC) method, demonstrated a substantial scavenging of free radicals and an effective antioxidant efficacy. …”
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Factors Affecting the Dividend Policy of Companies: A Meta-analysis Approach by Yalda Hassani, Bagher Asgarnezhad Nouri, Ghasem zarei, Allahyar Beigi Firoozi

“…However, the positive effect of free cash flow factors, profitability ratios, quality of financial reporting, effective tax rate, capital structure, institutional investors, information asymmetry, ability of managers, and concentration of ownership in dividend policy was confirmed.…”
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Modelling the Impact of Hygiene and Treatment on the Dynamics of Childhood Diarrhea in Nairobi County, Kenya by Veronicah Nyokabi Njenga, Cyrus Gitonga Ngari, Winifred Mutuku Nduku, Livingstone Serwadda Luboobi

“…In the analysis of the model, it was shown that the disease-free equilibrium of the model was locally and globally asymptotically stable if the effective reproduction number was less than unity, while the endemic equilibrium point was locally and globally asymptotically stable if the effective reproduction number was greater than unity. …”
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Socioeconomic inequalities in health behaviors in children and adolescents: evidence from an Australian cohort by Nirmal Gautam, Mohammad Mafizur Rahman, Rasheda Khanam

“…Children and adolescents with high SES were less likely to spend their free time on screens (RII = 0.86, 95% CI = 0.81–0.91) and more inclined toward outdoor activities (RII = 1.75, 95% CI = 1.53–1.98). …”
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Development and experimental validation of a machine learning model for the prediction of new antimalarials by Mukul Kore, Dimple Acharya, Lakshya Sharma, Shruthi Sridhar Vembar, Sandeep Sundriyal

“…The open-access and code-free KNIME platform was used to develop a workflow to train the model on 80% of data (N ~ 12k). …”
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Targeted co-delivery nanosystem based on methotrexate, curcumin, and PAMAM dendrimer for improvement of the therapeutic efficacy in cervical cancer by Ayuob Aghanejad, Shiva Kheiriabad, Maryam Ghaffari, Simin Namvar Aghdash, Neda Ghafouri, Jafar Ezzati Nazhad Dolatabadi, Hashem Andishmand, Michael R. Hamblin

“…The cell study results revealed that Cur-PAMAM-MTX NC exhibited significantly higher cytotoxicity than free MTX, Cur, and other formulations tested in vitro. …”
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Activity of gemmogenesis in regenerated plants of hazelnut cv. ‘Akademyk Yablokov’ and antibiotic therapy for elimination of bacterial contamination <i>in vitro</i> by T. A. Krasinskaya

“…Neither single nor twofold exposure to cefotaxime sodium salt at a concentration of 90 mg/L caused elimination of bacterial infection, but gemmogenesis and regenerated plant growth retained their activity during subsequent cultivation on antibiotic-free media. The best development parameters were observed on a modified Murashige–Skoog medium with 6 mg/L 6-BA, 0.01 mg/L IBA, and 0.1 mg/L GA3 (average number of shoots: 2.2; number of microcuttings: 2.3), and a modified DKW medium with 6 mg/L 6-BA, 0.01 mg/L IBA, and 0.1 mg/L GA3 (average number of shoots: 2.05; microcuttings: 2.9). …”
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Dégradation des écosystèmes steppiques et stratégie de développement durable. Mise au point méthodologique appliquée à la Wilaya de Nâama (Algérie) by Tarik B. Bouchetata, Arslan A. Bouchetata

“…At last, the analysis of strategies based on the objectif’s forking allow to free three complementary programs having for specific objectives: the restoring of balance liverstock/course, the suppression of illicitly plough and the rational management of the steppes ecosystem.…”
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Andrographolide-encapsulated nanoliposomes with gum Arabic surface modification inhibits cervical cancer growth: In vitro and in silico approaches by Rahmalillah Khairiah, Dwi Hudiyanti, Parsaoran Siahaan, Fadzilah Adibah Abdul Majid, Enny Fachriyah, Nor Hafizah Zakaria

“…The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenylte-trazolium bromide (MTT) experiment revealed that encapsulated AND inhibited HeLa cervical cancer cells more in comparison to free AND. Strong contact was shown by the docking score and binding energy of AND binding to the HPV 18B E6 receptor, which were determined by molecular docking and dynamic simulations to be −6.72 kcal/mol and − 90.002 kJ/mol, respectively. …”
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