Strong Bonding of Lattice N Activates Metal Ni to Achieve Efficient Water Splitting by Niandan Zhao, Wei Luo, Sijun Li, Hua Wang, Yini Mao, Yimin Jiang, Wenbin Wang, Ming Li, Wei Su, Rongxing He

“…Abstract Developing efficient and robust free‐standing electrocatalysts for overall water splitting is a promising but challenging task. …”
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Influencing factors and quantitative prediction of gas content of deep marine shale in Luzhou block by Xinyang He, Kun Zhang, Shu Jiang, Zhenxue Jiang, Xueying Wang, Wei Jiang, Jing Li, Yijia Wu, Zhi Gao, Tian Tang, Cheng Yang, Xuejiao Yuan, Fengli Han, Zeyun Wang, Laiting Ye

“…Conclusions below have been reached: the content of adsorbed gas is mainly affected by Ro, TOC content, porosity, water saturation, clay mineral content, formation temperature and pressure; the content of free gas is mainly controlled by porosity, water saturation, formation temperature and pressure; according to the prediction models, the adsorbed gas content, free gas content and total gas content of each well were quantitatively calculated, and the study area was divided into Class I (with a total gas content ≥ 11 m3/t), Class II (with a total gas content between 9 m3/t and 11 m3/t), and Class III (with a total gas content < 9 m3/t) gas-bearing areas.…”
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The contribution of different polyphenol compositions from chokeberry produced in China to cellular antioxidant and antiproliferative activities by Ningxuan Gao, Xu Si, Wenzhong Han, Ersheng Gong, Chi Shu, Jinlong Tian, Yuehua Wang, Jiyue Zhang, Binxu Li, Bin Li

“…The antiproliferative activity mainly depended on the proportion of free polyphenols and proanthocyanidins in total polyphenols. …”
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Immunology and Oxidative Stress in Multiple Sclerosis: Clinical and Basic Approach by Genaro G. Ortiz, Fermín P. Pacheco-Moisés, Oscar K. Bitzer-Quintero, Ana C. Ramírez-Anguiano, Luis J. Flores-Alvarado, Viridiana Ramírez-Ramírez, Miguel A. Macias-Islas, Erandis D. Torres-Sánchez

“…The inflammatory environment in demyelinating lesions leads to the generation of oxygen- and nitrogen-free radicals as well as proinflammatory cytokines which contribute to the development and progression of the disease. …”
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Interdependence of coagulation with immunotherapy and BRAF/MEK inhibitor therapy: results from a prospective study by Malte Beckmann, Julian Schlüter, Michael Erdmann, Rafaela Kramer, Sarah Cunningham, Holger Hackstein, Robert Zimmermann, Lucie Heinzerling

“…In addition, the influence of coagulation parameters on progression-free, recurrence-free and overall survival was investigated. …”
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The prognostic value of systemic inflammation response index in digestive system carcinomas: a systematic review and meta-analysis by Zuo-hu Niu, Li Lin, Hong-ye Peng, Xin-zhuo Zheng, Mi-yuan Wang, Feng-xia Sun, Chun-jun Xu

“…The primary outcome of interest was the overall survival (OS), while secondary outcomes included progression-free survival (PFS), disease-free survival (DFS), time to progression (TTP), and disease specific survival (DSS). …”
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Prognosis of nodal micrometastasis in resectable pN0 non-small cell lung cancer by Sophon Siwachat, Sophon Siwachat, Sophon Siwachat, Apichat Tantraworasin, Apichat Tantraworasin, Apichat Tantraworasin, Nirush Lertprasertsuke, Somcharoen Saeteng, Somcharoen Saeteng

“…Overall survival is the primary endpoint, with disease-free survival as the secondary endpoint.ResultsOut of 225 patients, 98 had pathological N0 (pN0) status and 127 had pathological N positive (pN+) status. …”
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Search for and functional annotation of multi-domain PLA2 family proteins in flatworms by M. E. Bocharnikova, I. I. Turnaev, D. A. Afonnikov

“…The paper provides a search for and a comparative analysis of PLA2 sequences encoded in the genomes of flatworms. 44 species represented by two free-living and 42 parasitic organisms were studied. …”
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Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry by Aline Menezes, Yara Martins, Fábio Nogueira, Denise De Abreu Pereira, Katia Carneiro

“…To better investigate the GBM secretome upon in vitro treatment with histone deacetylase inhibitor (iHDAC), we employed a high-throughput label-free methodology of protein identification and quantification based on mass spectrometry followed by in silico studies. …”
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Effects of Source on the Nitrogen Uptake, Allocation Patterns, and Performance of Strawberry (<i>Fragaria × ananassa</i> Duch.): A ¹⁵N-Tracer Study by Sirajo Salisu Jibia, Kanokwan Panjama, Chaiartid Inkham, Takashi Sato, Norikuni Ohtake, Soraya Ruamrungsri

“…Five treatments were applied: T1 (5.0 mM ¹⁵NO₃⁻), T2 (2.5 mM ¹⁵NO₃⁻ + 2.5 mM NH₄⁺), T3 (5.0 mM ¹⁵NH₄⁺), T4 (2.5 mM ¹⁵NH₄⁺ + 2.5 mM NO₃⁻), and T5 (N-free, control) in a completely randomized design. …”
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Black mulberry (Morus nigra L.) prevents deleterious effects of excess glucose in obese C. elegans decreasing lipofuscin accumulation and ROS production by Sonia Núñez, Adrián Millán-Laleona, Javier Cano-Lou, Andrea Corella, Cristina Moliner, Guillermo Cásedas, Filippo Maggi, Víctor López, Carlota Gómez-Rincón

“…The capacity of the extract to inhibit advance glycation end products and free radicals as well as pancreatic lipase and α-amylase was also evaluated in vitro. …”
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Fluorescence Lifetime Imaging of NAD(P)H in Patients’ Lymphocytes: Evaluation of Efficacy of Immunotherapy by Diana V. Yuzhakova, Daria A. Sachkova, Anna V. Izosimova, Konstantin S. Yashin, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev, Artem M. Mozherov, Vladislav I. Shcheslavskiy, Marina V. Shirmanova

“…Results: The results demonstrate that the responsive models displayed a significant increase in the free NAD(P)H fraction α₁ after treatment, associated with a shift towards glycolysis due to lymphocyte activation. …”
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<i>Musa paradisiaca</i> L. Inflorescence Abrogates Neutrophil Activation by Downregulating TLR4/NF-KB Signaling Pathway in LPS-Induced Acute Lung Injury Model by Francisco Allysson Assis Ferreira Gadelha, Raquel Fragoso Pereira Cavalcanti, Cosmo Isaias Duvirgens Vieira, Joao Batista De Oliveira, Louíse Mangueira De Lima, Adriano Francisco Alves, Matheus Marley Bezerra Pessoa, Leônia Maria Batista, Naiara Naiana Dejani, Marcia Regina Piuvezam

“…<b>Conclusions</b>: Therefore, HEM’s anti-inflammatory and immunomodulatory activities in ALI mice are by deactivating neutrophils by decreasing CD18 receptor, free DNA release, and MPO activity and inducing IL-10 production. …”
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Spatial distribution and influencing factors of secondhand smoke exposure in Chinese healthcare facilities: a cross-sectional survey by Ying LIU, Xinying ZENG, Lin XIAO, Shiwei LIU

“…Sex ratio, the proportions of individuals aged 0 – 14 years and 15 – 64 years, illiteracy rate, tobacco consumer price index, and the proportion of cities with smoke-free legislation are the main influencing factors of SHS exposure in healthcare facilities in China.…”
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Validation of a Real Time PCR for Classical Swine Fever Diagnosis by Natanael Lamas Dias, Antônio Augusto Fonseca Júnior, Anapolino Macedo Oliveira, Érica Bravo Sales, Bruna Rios Coelho Alves, Fernanda Alves Dorella, Marcelo Fernandes Camargos

“…Furthermore, RNA from CSF virus was not detected in samples of swine originated from the Brazilian CSF-free zone. Hence, it is concluded that RT-qPCR can be used as a complementary diagnostic for CSF.…”
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Screening for schistosomiasis in a non-endemic setting: Accuracy of a rapid antibody test using finger prick blood by Margherita Ortalli, Bianca Granozzi, Michele Bacchiega, Concettina Di Lillo, Greta Roncarati, Silvia Stefania Longoni, Cristina Mazzi, Elisa Vanino, Zeno Bisoffi, Stefania Varani

“…Serological screening is recommended but so far, no accurate point-of-care (POC) and lab-free test is available.We carried out a prospective evaluation of the accuracy of a new immunochromatographic test (Black- ICT, IgG-IgM) using finger prick blood for screening of schistosomiasis at the University Hospital of Bologna. …”
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Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe... by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

“…The primary endpoint of the study is the 1-year progression-free survival (PFS) rate, measured as the percentage of patients who are free of tumour progression or death for 1 year after receiving the first dose of study drug. …”
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Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice by Yan Yang, Wenting Zhang, Xiaohui Wu, Jing Wu, Chengjun Sun, Feihong Luo, Zhou Pei

“…Compared to that of cells in the FAA-free control group, LO2 cells with in situ overexpression of GDF5 developed lipid droplets after FFA treatment; the levels of triglycerides, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were significantly increased in both the GDF5 lentivirus and control lentivirus groups compared with those of the FAA-free group. …”
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Nose-to-Brain Delivery of Chitosan-Grafted Leciplexes for Promoting the Bioavailability and Antidepressant Efficacy of Mirtazapine: In Vitro Assessment and Animal Studies by Amani M. El Sisi, Essam M. Eissa, Ahmed H. E. Hassan, Marina A. Bekhet, Fatma I. Abo El-Ela, Eun Joo Roh, Rasha M. Kharshoum, Adel A. Ali

“…Intranasal delivery of the tailored CS-MRZ-LPX revealed notably superior pharmacokinetic attributes inside the brain and circulation compared to the orally administered MRZ suspension and the intranasal free drug suspension (<i>p</i> < 0.05); the relative bioavailability was 370.9% and 385.6% for plasma and brain, respectively. …”
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Safety of vancomycin-loaded cement spacers for treating gram-positive periprosthetic joint infections in two-stage resection arthroplasty among patients with renal insufficiency by Yu-Chih Lin, Chih-Hsiang Chang, Chih-Chien Hu, Yung-Chieh Liang, Pang-Hsin Hsieh, Sheng-Hsun Lee, Sheng-Hsuan Lin

“…Additionally, renal insufficiency did not adversely affect the infection-free interval, aseptic revision rates, or bacterial diversity. …”
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