Metabolomic approach to investigate <i>Dactylis glomerata</i> L. from the VIR collection by N. Yu. Malysheva, T. V. Shelenga, A. E. Solovyeva, T. B. Nagiev, N. V. Kovaleva, L. L. Malyshev

“…Wild-growing accession k-44020 from Norway surpassed other wild-growing accessions in the content of free amino acids, sugars and phosphates at the heading stage. …”
Get full text

Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis by Adriana Bezerra-Souza, Jéssica A. Jesus, Márcia D. Laurenti, Aikaterini Lalatsa, Dolores R. Serrano, Luiz Felipe D. Passero

“…Animals topically treated with butenafine (free or nanoformulated) showed small dermal lesions and low tissue parasitism. …”
Get full text

Flat-band based high-temperature ferromagnetic semiconducting state in the graphitic C4N3 monolayer by Chaoyu He, Yujie Liao, Tao Ouyang, Huimin Zhang, Hongjun Xiang, Jianxin Zhong

“…Interestingly, such a corrugated Pca21 C4N3 monolayer is found to be both piezoelectric and ferroelectric, which makes it an unusual metal-free two-dimensional multiferroic.…”
Get full text

Outpatient Versus Inpatient Total Joint Arthroplasty: Do Medically and Socially Complex Patients Require More Resources but Achieve Similar Outcomes? by Justin Leal, BS, Christine J. Wu, MD, Niall H. Cochrane, MD, Thorsten M. Seyler, MD, PhD, William A. Jiranek, MD, Samuel S. Wellman, MD, Michael P. Bolognesi, MD, Sean P. Ryan, MD

“…Results: Patients in the inpatient total knee arthroplasty group had a higher proportion of patients requiring an emergency department visit (11.4% vs 4.5%; P = .008) and admission (6.7% vs 2.7%; P = .025) within the first 90 days after surgery than the outpatient group; however, 2-year revision-free (97.9% vs 97.9%; P = .75) survival was similar between groups. …”
Get full text

Preparation and In Vitro Evaluation of Alginate Microparticles Containing Amphotericin B for the Treatment of Candida Infections by Merlis P. Alvarez-Berrios, Lisa M. Aponte-Reyes, Lourdes Diaz-Figueroa, Juan Vivero-Escoto, Alexis Johnston, David Sanchez-Rodriguez

“…Although they have the ability to reduce the main side effects of free AmB, their high cost, necessity of repeated intravenous injections for successful treatment, and incidence of pulmonary toxicity have limited their use. …”
Get full text

Novel Poly-Arginine Peptide R18D Reduces α-Synuclein Aggregation and Uptake of α-Synuclein Seeds in Cortical Neurons by Emma C. Robinson, Anastazja M. Gorecki, Samuel R. Pesce, Vaishali Bagda, Ryan S. Anderton, Bruno P. Meloni

“…Thereafter, this study examined the therapeutic potential of the neuroprotective CARP, R18D (18-mer of D-arginine), to prevent the aforementioned PD pathogenic processes through a cell-free thioflavin-T (ThT) assay and in cortical neurons. …”
Get full text

Effects of V on the dual-phase heterostructure FeCrNiVx medium-entropy alloys by Peng Sang, Ningning Liang, Lei Gu, Liangyu Chen, Yuan Lei, Zan Zhang, Yongsheng Li

“…The results supply a strategy of designing of Co-free dual-phase MEA with outstanding cost/performance advantage.…”
Get full text

Optimization of the Fermentation Process for Pine-needle Sweet-potato Glutinous Rice Wine and Analysis of Its Antioxidant Activity by Jie YOU, Rusheng XIE, Weibin WU

“…In terms of antioxidant capacity, the scavenging rates of the DPPH and ABTS+ free radicals of the pine-needle sweet-potato glutinous rice wine were as high as 87.2% and 90.3%, respectively, which were significantly higher than those of traditional sweet-potato glutinous rice wine (P<0.05). …”
Get full text

Unraveling the transcriptomic effects of leucine supplementation on muscle growth and performance in basketball athletes. by Sinan Wang, Weishuai Guo, Rui Dong

“…Baseline exercise performance-assessed through a 282-foot sprint, free throws, three-point field goals, and self-rated practice assessments-was measured prior to leucine supplementation. …”
Get full text

Effect of proteolytic starter culture isolated from Chinese Dong fermented pork (Nanx Wudl) on microbiological, biochemical and organoleptic attributes in dry fermented sausages by Xi Chen, Ruifang Mi, Biao Qi, Suyue Xiong, Jiapeng Li, Chao Qu, Xiaoling Qiao, Wenhua Chen, Shouwei Wang

“…The addition of LS starter accelerated acidification and proteolysis during ripening, improving the contents of total free amino acids and several essential free amino acids (Phe, Ile and Leu). …”
Get full text

Time-Dependent Prognostic Impact of Circulating Tumor Cells Detection in Non-Metastatic Breast Cancer: 70-Month Analysis of the REMAGUS02 Study by François-Clément Bidard, Lisa Belin, Suzette Delaloge, Florence Lerebours, Charlotte Ngo, Fabien Reyal, Séverine Alran, Sylvie Giacchetti, Michel Marty, Ronald Lebofsky, Jean-Yves Pierga

“…No prognostic impact is seen in patients who are still relapse-free at this moment.…”
Get full text

Survival outcomes of marijuana users in p16 positive oropharynx cancer patients by Han Zhang, Michael Xie, Marc Levin, Stuart D. Archibald, B. Stanley Jackson, J. E. M. Young, Michael K. Gupta

“…There was no statistically significant difference between marijuana and non-marijuana user groups in 5-year (p = 0.400) overall survival, disease-specific (p = 0.993), disease-free (p = 0.404), and metastasis-free survival (p = 0.384). …”
Get full text

Dual Biologic or Small Molecule Therapy in Pediatric Inflammatory Bowel Disease: A Single Center Experience by Cheng Guo, Jin Zhou, Guoli Wang, Jie Wu

“…PIBD patients who received dual biologic treatment or a combination of biologic and small molecule therapy were included in this study. Steroid-free clinical remission and adverse events were recorded. …”
Get full text

The Neurodevelopmental Dynamics of Multilingual Experience During Childhood: A Longitudinal Behavioral, Structural, and Functional MRI Study by Pasquale Anthony Della Rosa, Gerda Videsott, Virginia Maria Borsa, Eleonora Catricalà, Nicolò Pecco, Federica Alemanno, Matteo Canini, Andrea Falini, Rita Franceschini, Jubin Abutalebi

Get full text

Structure-Based Virtual Screening, Docking, ADMET, Molecular Dynamics, and MM-PBSA Calculations for the Discovery of Potential Natural SARS-CoV-2 Helicase Inhibitors from the Tradi... by Ahmed M. Metwaly, Alaa Elwan, Abdul-Aziz M. M. El-Attar, Sara T. Al-Rashood, Ibrahim H. Eissa

“…Finally, MM-PBSA studies showed that 533 bonded favorably to SARS-CoV-2 helicase with a free energy value of −83 kJ/mol. Further, the free energy decomposition study determined the essential amino acid residues that contributed favorably to the binding process. …”
Get full text

Ultra‐Broad Emission Copper Halide Scintillator‐Based X‐Ray Imager by Haocheng Lv, Wenyi Shao, Haifeng Chen, Guoyang Zhu, Yao Wang, Zhenzhong Zhang, Hongwei Liang

“…Abstract Lead‐free metal‐halide scintillators are gaining considerable attention as more eco‐friendly and superior alternatives to their lead‐based counterparts. …”
Get full text

Real-World Clinical Outcomes and Treatment Patterns Among Black and Non-Black Patients With Prostate Cancer Initiated on Apalutamide in a Urology Setting by Benjamin H. Lowentritt, Carmine Rossi, Erik Muser, Frederic Kinkead, Bronwyn Moore, Patrick Lefebvre, Dominic Pilon, Shawn Du

“…Clinical outcomes described up to 24 months after apalutamide initiation using Kaplan-Meier analyses included progression to castration resistance, castration resistance-free survival (CRFS), and metastasis-free survival (MFS). …”
Get full text

Hypercalcemia and co-occurring TBX1 mutation in Glycogen Storage Disease Type Ib: case report by Zakaria Kasmi, Imane Ain El Hayat, Zahra Aadam, Abderrahmane Errami, Ibtihal Benhsaien, Jalila EL Bakkouri, Dalal Ben Sabbahia, Meryem Atrassi, Ahmed Aziz Bousfiha, Fatima Ailal

“…Initial management included a lactose-free and galactose-free diet, multivitamin supplementation, and granulocyte colony-stimulating factor (G-CSF) therapy to address neutropenia. …”
Get full text

High-Coercivity Ferrimagnet Co₂FeO₂BO₃: XMCD Insights into Charge-Ordering and Cation Distribution by Mikhail S. Platunov

“…The multi-sublattice ferrimagnet Co₂FeO₂BO₃, a prominent example of lanthanide-free magnets, was the subject of element-selective studies using X-ray magnetic circular dichroism (XMCD) observations at the <i>L</i>- and <i>K</i>- X-ray absorption edges. …”
Get full text

Nutritional Status and Cardiovascular Health in Female Adolescent Elite-Level Artistic Gymnasts and Swimmers: A Cross-Sectional Study of 31 Athletes by Boštjan Jakše, Barbara Jakše, Nataša Fidler Mis, Borut Jug, Dorica Šajber, Uroš Godnov, Ivan Čuk

“…Gymnasts had higher body mass index (21.5 vs. 20.1 kg/m2, p=0.043) and lower fat free mass (42.4 vs. 46.6 kg, p=0.024) than swimmers and comparable body fat percentage (22.5 vs. 22.8%). …”
Get full text