A New Risk Score Based on Lipid Indicators for Patients with Advanced Hepatocellular Carcinoma by Wei X, Guo Z, Zhang T, Liang J

“…Using the COX proportional risk model analysis method, we then created a risk score and examined them using Kaplan-Meier, time-dependent receiver operating characteristics (ROC) curve, and nomogram analysis.Results: In predicting overall survival (OS), free fatty acid/high-density lipoprotein cholesterol (FFHL), tumor size, and BCLC stage were independent prognostic variables. …”
Get full text

An In Vitro Pilot Study Comparing the Novel HemoClear Gravity-Driven Microfiltration Cell Salvage System with the Conventional Centrifugal XTRA™ Autotransfusion Device by Anneloes Hoetink, Sabine F. Scherphof, Frederik J. Mooi, Paul Westers, Jack van Dijk, Sjef J. van de Leur, Arno P. Nierich

“…The centrifugal device reduced solutes more significantly by up to 99%. Free hemoglobin load was reduced to 12.9% and 15.5% by the XTRA™ and HemoClear, respectively. …”
Get full text

Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Erdafitinib vs Enfortumab Vedotin in Patients with Locally Advanced Metastatic Urothelial Carcinoma by Suzy Van Sanden, Ayman Youssef, Simona Baculea, Keith Stubbs, Spyros Triantos, Zijiao Yuan, Caitlin Daly

“…**Conclusion:** The MAIC indicates comparable efficacy of erdafitinib vs EV for overall survival and progression-free survival, with erdafitinib showing a higher probability of achieving deep responses. …”
Get full text

Early childhood caries and their association with serum iron, serum ferritin, serum albumin, and Vitamin D by Vasundhara Megha, Jeevendra Nath Shukla, Rajat Kumar Singh, Chitrita Gupta Mukherjee, Siddharth Anand, Aparna Singh

“…The mean value of Vitamin D was 17.44 (±7.59) ng/ml in ECC children and 35.9 (±9.56) in caries-free children who were significantly low in comparison with the non-ECC subjects (P < 0.0001). …”
Get full text

Bioactivity of Walnut: Investigating the Triterpenoid Saponin Extracts of Juglans regia Kernels for Antioxidant, Anti-diabetic, and Antimicrobial Properties by Youssef Elouafy, Salma Mortada, Adil El Yadini, Mohamed Hnini, Youssra Aalilou, Hicham Harhar, Asaad Khalid, Ashraf N. Abdalla, Abdelhakim Bouyahya, My El Abbes Faouzi, Mohamed Tabyaoui

“…Antioxidant activity was assessed against two free radicals: DPPH and ABTS. Oleanolic acid was used as a standard to quantify triterpenoid saponins, measured by the vanillin method, whereas Acarbose and Tetracycline were used as positive controls to evaluate the α-glucosidase inhibitory and antimicrobial activities, respectively, of walnut kernel extracts. …”
Get full text

Rationale and design of the multicenter, national, randomized, open labeled phase III trial: allogeneic stem cell transplantation as a potential curative treatment for patients wit... by Annemarie Glöckner, Stefan Schönland, Hermann Einsele, Nicolaus Kröger

“…Patients with multiple myeloma who relapse after initial high-dose chemotherapy with autologous stem cells have a median progression free survival up to 2–3 years, depending on risk factors such as previous remission duration. …”
Get full text

Impact of gender on the prognosis of carotid body tumor after surgical resection by Huanrui Hu, Yuwei Xiang, Bin Huang, Ding Yuan, Yi Yang, Jichun Zhao

“…Conclusions Compared to females, males with CBT resection were found to have more SDHB mutations and worse relapse-free survival rates, which may lead to the deterioration of prognosis. …”
Get full text

Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA by Tobias Solli Iveland, Lars Hagen, Mirta Mittelstedt Leal de Sousa, Nina Beate Liabakk, Per Arne Aas, Animesh Sharma, Bodil Kavli, Geir Slupphaug

“…HDAC inhibition apparently exacerbates cytotoxicity of these agents by inhibiting error-free repair of misincorporated ribonucleotides in DNA. …”
Get full text

Post-operative Rehabilitation for Scapular Muscle Reattachment: A Case Report by Wendy Burke, W Ben Kibler, Tim L Uhl

“… # Outcomes The American Shoulder and Elbow Surgeons (ASES) Standardized Assessment Form and pain-free range of motion was used pre- and postoperatively. …”
Get full text

Study of vascular endothelial dysfunction in children with beta-thalassemia major before and after quercetin therapy by Fatma Al Zahraa Sherai, Maaly Mabrouk, Ibrahim Badraia, Adel Hagag, Eman Elaskary

“…It occurs due to erythroid expansion along with ineffective erythropoiesis. The free hemoglobin oxidation generates reactive oxygen species (ROS), free heme, and iron, thus inducing membrane oxidative damage as well as vascular endothelial dysfunction. …”
Get full text

NEW ROLE FOR THE TEACHER: PREVENT STUDENTS FROM COMPLETELY ABANDONING THEMSELVES TO AI AND RELINQUISHING CONTROL OVER THEIR LEARNING. Illustration for foreign languages for specifi... by Felicia CONSTANTIN

“…The teacher will introduce free chatbots (ChatGPT or similar) in a controlled way in the didactic course proposed for economics students learning business French. …”
Get full text

MINERALOGY AND ORE FORMATION CONDITIONS OF THE NAILY GOLD DEPOSIT (SOUTH URALS) by A.D. Smirnitskaya, E.A. Rozhkova, E.V. Belogub, K.A. Novoselov, M.V. Zabotina, M.A. Rassomakhin

“…Silver is also incorporated in acanthite and Hg-Ag-Sb-As, Pb-Bi-Ag and Cu-Ag-Pb-Bi sulfosalts. The Ag content of free native gold is 10–16 wt. % increasing to 20–24 wt. % in native gold in pyrite and in assemblage with hessite. …”
Get full text

Early Maternal Deprivation Enhances Voluntary Alcohol Intake Induced by Exposure to Stressful Events Later in Life by Sara Peñasco, Virginia Mela, Jose Antonio López-Moreno, María-Paz Viveros, Eva M. Marco

“…During adolescence, when animals had free access to alcohol, MD animals showed lower body weight gain but a higher growth rate than control animals. …”
Get full text

Mass resection as a candidate treatment for uterine PEComas of uncertain malignant potential: a case report and literature review by Haijuan Shi, Yan Yin, Shoujun Liang, Chuanzhong Liu, Yibao Huang, Bingfeng Lu, Liying Zhang

“…Except for the patients who were lost to follow-up, 11 patients were free of any recurrence or metastasis at their last follow-up. …”
Get full text

Damage Identification in Large-Scale Structures Using Time Series Analysis and Improved Sparse Regularization by Huihui Chen, Xiaojing Yuan

“…Furthermore, regarding the numerical example, the damage identification results show that the max identification errors of the proposed method are 6% among the three cases under noise-free and noise-polluted data, while the max identification errors for MFO and the regularization method are 15% and 10%, respectively. …”
Get full text

Potential of Co(II) and Cd(II) chelates of N′-(3-fluorobenzoyl)benzo[d]thiazole-2-carbohydrazide: Structural aspects, binding interactions, biological and molecular docking studies... by K. Srilaxmi, B. Sireesha

“…The light switching properties of the complexes, the hydrolytic and oxidative cleavage of CT-DNA by gel electropheresis were evaluated. The DPPḢ free radical scavenging method was used to assess antioxidant properties. …”
Get full text

Phenolics from grapefruit peels inhibit HMG-CoA reductase and angiotensin-I converting enzyme and show antioxidative properties in endothelial EA.Hy 926 cells by Ayokunle O. Ademosun, Ganiyu Oboh, Sabina Passamonti, Federica Tramer, Lovro Ziberna, Aline Augusti Boligon, Margareth Linde Athayde

“…There was no significant (P > 0.05) difference in the HMG-CoA reductase inhibitory ability of the two extracts, while the bound phenolic extracts had a stronger ACE inhibitory ability than the soluble free phenolics. The extracts also showed intracellular antioxidant activity in human endothelial (EA.Hy 926) cells. …”
Get full text

Understanding perception of the radiology community concerning virtual reality (VR) and augmented reality (AR) technology in radiology education by Suneet Paulson, Dwight Figueiredo, Sushant Matre

“…This review talks about the key applications of VR and AR to provide students with real-world training where students gain hands-on experience in a risk-free and controlled environment. Virtual radiography simulation can be used to practice and enhance patient positioning skills without getting exposed to any X-ray radiation. …”
Get full text

A conceptual mechanistic model of amino acid fluxes in the small intestine, taking the example of pig by C.J.J. Garçon, N. Le Floc’h, Y. Mercier, J. van Milgen

“…., dietary or endogenous), and form (i.e., as protein or as a free AA). The pools were connected by fluxes, representing the main fates of AA, such as saturable transport of luminal AA or homeostasis of free or protein-bound AA in intestinal tissue. …”
Get full text

One-stage versus two-stage video-assisted thoracic surgery for synchronous bilateral pulmonary nodules: protocol for a single center, non-randomized clinical trial (OTVATS-1) by Yu Han, Weixun Zhang, Peihang Xu, Zhoujunyi Tian, Yang Hao, Jin Zhang, Tai Ren, Chaoyang Liang

“…Secondary outcomes include 5-year disease free survival, 3-year overall survival, 3-year disease free survival, overall complications rate, 30-day mortality, pain score after surgery, surgical time, blood loss in the operation, duration of chest tube, length of stay, and quality of life score after surgery. …”
Get full text