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121
Development and In-Vitro Evaluation of pH Responsive Polymeric Nano Hydrogel Carrier System for Gastro-Protective Delivery of Naproxen Sodium
Published 2019-01-01“…Polyethylene glycol-g-poly (methacrylic acid) nanogels was developed through free radical polymerization technique. Formulation was characterized for swelling behaviour, entrapment efficiency, Fourier transform infrared (FTIR) spectroscopy, Differential scanning calorimetry (DSC), and Thermal Gravimetric Analysis (TGA), Powder X-ray diffraction (PXRD), Zeta size distribution, and Zeta potential measurements, and in-vitro drug release. pH dependent swelling was observed with maximum drug release at higher pH. …”
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122
Acute Toxicity and Antioxidant and Antibacterial Activities of Kyllinga polyphylla Willd. ex Kunth, Cyperaceae Family
Published 2024-01-01“…All parts of KP had the free radical scavenging capacity of DPPH, in which the root methanol extract had the best antioxidant capacity (EC50 = 9.54 ± 0.37 μg/mL). …”
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123
Exposure of cerebellar granule cells to nanosilver: Oxidative stress parameters and the protective effect of exogenous glutathione
Published 2024-10-01“…The results indicate that exposure of CGCs to AgNPs decreases cell viability and mitochondrial potential and increases intracellular calcium concentration and free radical production. The level of intracellular GSH significantly decreases in cells after short-term exposure, but overexpression of SOD1 is observed. …”
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124
Phytochemical Screening, Polyphenols Content, Antioxidant Power, and Antibacterial Activity of Herniaria hirsuta from Morocco
Published 2018-01-01“…Extracts were screened for their possible antioxidant activities by three tests: DPPH free radical-scavenging, reducing power, and molybdenum systems. …”
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125
Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don
Published 2022-01-01“…Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. …”
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126
A Photochromic Copolymer Hydrogel Contact Lens: From Synthesis to Application
Published 2016-01-01“…A photochromic poly(2-hydroxyl-ethyl methacrylate-N-vinylpyrrolidone-spironaphthoxazine) hydrogel (p(HEMA-NVP-SPO)) has been designed and synthesized by free radical polymerization in this work. The chemical and structural information of hydrogels was investigated by IR spectra, equilibrium water content (EWC), and SEM. …”
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127
Advances in Research on the Interaction of Food-derived Polysaccharide and Polyphenol
Published 2025-02-01“…This paper describes the means of characterizing food-derived polysaccharide and polyphenol interactions, including Fourier transform infrared (FT-IR) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy, and interaction mechanisms such as enzyme-catalyzed reactions and free radical-induced reactions was also summarized. In addition, this paper focuses on the effects of concentration, pH, temperature and ionic strength on the interaction between polysaccharides and polyphenols, and further generalizes the alteration of physicochemical properties such as solubility and crystallinity, as well as bioactivities such as antioxidant and antimicrobial activities of polysaccharides and polyphenols under the interaction. …”
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128
Enhanced antioxidant performance of phlorotannin compounds from brown seaweed Sargassum tenerrimum via nanoliposomal encapsulation
Published 2025-03-01“…Additionally, total antioxidant activity, free radical scavenging, and iron reduction improved significantly (p < 0.05) due to the large surface area and high antioxidant load capacity of NLs. …”
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129
Untargeted metabolomics of Aloe volatiles: Implications in pathway enrichments for improved bioactivities
Published 2025-02-01“…The leaves of five highly utilized Aloe sp. were subjected to untargeted gas chromatography-mass spectrometry analysis followed by testing of free-radical scavenging effects against components of the Fenton and Haber-Weiss reaction. …”
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130
Advancements in electron paramagnetic resonance (EPR) spectroscopy: A comprehensive tool for pharmaceutical research
Published 2024-12-01“…We detail how EPR spectroscopy can be employed to assess free radical scavenging properties in pharmaceutical compounds, elucidate drug mechanisms of action, and explore pharmacokinetics. …”
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131
Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies?
Published 2015-01-01“…The mechanisms responsible for these effects of lutein and zeaxanthin include prevention of phototoxic damage by absorption of blue light, reduction of oxidative stress through antioxidant activity and free radical scavenging, and their anti-inflammatory and antiangiogenic properties. …”
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132
Involvement of Coenzyme Q10 in Various Neurodegenerative and Psychiatric Diseases
Published 2023-01-01“…Second, this molecule has an antioxidant and free-radical scavenger nature. Since then, several investigations have indicated that the drug may benefit patients with cardiovascular, neuromuscular, and neurodegenerative illnesses. …”
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133
Chemical Composition, Total Phenolic Content, and Antioxidant Activity of the Essential Oils Extracted from the Needle of Ten Pinus Taxa
Published 2022-01-01“…Furthermore, we determined the total phenolic content (TPC) of the EOs, with the values from 26.50 to 60.01 mg eq GAE/mL EO. DPPH free radical scavenging activity (DPPH), ferric reducing antioxidant power (FRAP), and ABTS radical cation scavenging activity (ABTS) were used to evaluate the antioxidant capacity of the EOs, and the obtained values were ranged from 499.15 to 1,272.75 mmol eq Trolox/mL EO, 1,255.67 to 3,857.93 mmol eq Trolox/mL EO, and 370.81 to 1,677.19 mmol eq Trolox/mL EO, respectively. …”
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134
Anticholinesterase Toxicity and Oxidative Stress
Published 2006-01-01“…However, the mechanism(s) involved in brain/muscle damage appear to be linked with alteration in antioxidant and the scavenging system leading to free radical-mediated injury. OPs and CMs cause excessive formation of F2-isoprostanes and F4-neuroprostanes, in vivo biomarkers of lipid peroxidation and generation of reactive oxygen species (ROS), and of citrulline, a marker of NO/NOS and reactive nitrogen species (RNS) generation. …”
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135
In Vitro Antioxidant Capacity and Neuronal Cell Toxicity of Roots of Ostericum koreanum Maximowicz
Published 2011-01-01“…These results suggest that O. koreanum shows good antioxidant activities in vitro by inhibiting free radicals. These findings provide a rationale for the in vivo testing. …”
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136
Microwave-Assisted Synthesis of Cross-Linked Co-poly(itaconic anhydride-methyl methacrylate): The Effects of the Molar Ratio and Cross-Linking Agent on the Thermal Stability
Published 2020-01-01“…In the present work, a new series of cross-linked copolymers based on itaconic anhydride and methyl methacrylate were prepared employing free radical copolymerization in the presence of azobisisobutyronitrile as an initiator and 2-butanone as a solvent under microwave irradiation. …”
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137
New Insights into Aspirin’s Anticancer Activity: The Predominant Role of Its Iron-Chelating Antioxidant Metabolites
Published 2024-12-01“…The mechanisms of cancer risk reduction in LTLDA users is likely due to the ACM’s targeting of iron involved in free radical damage, iron-containing toxins, iron proteins, and associated metabolic pathways such as ferroptosis. …”
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138
INTENSITY OF NITRIC OXIDE SYNTHESIS IN THE BLOOD OF RATS UNDER THE INFLUENCE OF SODIUM FLUORIDE
Published 2020-12-01“…It is known that when the rate of free radical reactions in the body increases, NO can react with a superoxide anion radical to form peroxynitrite, a highly reactive compound with destructive properties against proteins and lipids. …”
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139
Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Bin...
Published 2018-01-01“…The in vitro antioxidant activity of all the compounds was determined by DPPH free radical-scavenging assay. Intercalative mode of DNA-binding properties of the oxidovanadium(IV) complexes with calf-thymus DNA (CT-DNA) was investigated using UV, fluorescence spectra, and viscosity measurements.…”
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140
Study on Properties of Branched Hydrophobically Modified Polyacrylamide for Polymer Flooding
Published 2013-01-01“…A new branched hydrophobically modified polyacrylamide (BHMPAM) was synthesized by the free radical copolymerization of functionalized branched macromolecular skeleton monomer, acrylamide (AM), acrylic acid (AA), and hydrophobic monomer hexadecyl-allyl-dimethyl ammonium chloride (C16DMAAC). …”
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