Core Prescribing Indicators and the Most Commonly Prescribed Medicines in a Tertiary Health Care Setting in a Developing Country by Priyadarshani Galappatthy, Priyanga Ranasinghe, Chiranthi K. Liyanage, Maheshi Wijayabandara, Dinuka S. Warapitiya, Dilini Jayasekara, Raveendra L. Jayakody

“…The five most commonly prescribed medicines were paracetamol (31.0%), omeprazole (20.6%), folic acid (18.3%), atorvastatin (16.2%), and salbutamol (15.3%). …”
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Determinants of Neural Tube Defects among Newborns in Amhara Region, Ethiopia: A Case-Control Study by Abay Woday Tadesse, Ayesheshim Muluneh Kassa, Setognal Birara Aychiluhm

“…However, being supplemented with folic acid or multivitamins before or during pregnancy (AOR=0.37: 95% CI 0.21, 0.65), never having taken any substance during pregnancy (AOR=0.42: 95% CI 0.21, 0.88), and being free from medical illnesses during pregnancy (AOR=0.27: 95% CI 0.11, 0.69) were the protective factors of NTDs. …”
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A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 Mice by Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan

“…A dietary approach (Fortasyn) including docosahexaenoic acid, eicosapentaenoic acid, uridine, choline, phospholipids, folic acid, vitamins B12, B6, C, and E, and selenium has been proposed for dietary management of AD. …”
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Hypovitaminosis D3, Leukopenia, and Human Serotonin Transporter Polymorphism in Anorexia Nervosa and Bulimia Nervosa by Anna Tasegian, Francesco Curcio, Laura Dalla Ragione, Francesca Rossetti, Samuela Cataldi, Michela Codini, Francesco Saverio Ambesi-Impiombato, Tommaso Beccari, Elisabetta Albi

“…We choose 18 patients with a normal blood test profile such as thyroid hormones, hepatic and renal parameters, triglycerides, proteins, vitamin B12, and folic acid. Among these emerged the case of a woman with long-term anorexia nervosa and the case of a woman with long-term bulimia nervosa both complicated by anxiety and depression, severe hypovitaminosis D3, decrease of vitamin D receptor, leukopenia, and 5-hydroxytryptamine transporter linked polymorphic region short allele. …”
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Iron supplementation post-blood donation in Vietnam: Impact on hemoglobin, red cell indices, and iron reserves by Viet Pham Tuan, Son Dao Anh, Phong Hoang Van, Tuan Anh Bui Sy

“…They received a daily iron supplement comprising 100 mg of elemental iron, 0.75 mg of folic acid, and 5 mg of zinc sulfate for a minimum of 8 weeks. …”
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Quality Assessment of Some Essential Children’s Medicines Sold in Licensed Outlets in Ashanti Region, Ghana by Grace Frimpong, Kwabena Ofori-Kwakye, Noble Kuntworbe, Kwame Ohene Buabeng, Yaa Asantewaa Osei, Mariam El Boakye-Gyasi, Ofosua Adi-Dako

“…All the ciprofloxacin, cotrimoxazole, flucloxacillin, artemether-lumefantrine, multivitamin, and folic acid samples failed the content of API test and are substandard. …”
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UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway by Lijie Yang, Penghui Si, Tuoheti Kuerban, Linfa Guo, Shanzhi Zhan, Yisha Zuhaer, Yingtong Zuo, Peixiang Lu, Xiaojie Bai, Tongzu Liu

“…By establishing a TGF-β1-stimulated HK2 cell model and animal models of renal fibrosis induced by UUO and folic acid, we confirmed that UHRF1 was highly expressed in both in vitro and in vivo models of renal fibrosis. …”
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Evaluating the association of depressive symptoms on serum folate and erythrocyte folate levels based on the 2017–2020 NHANES database by Yunhong Yang, Huaqian Qi, Jiahao Zhang, Jie Jia, Yunsong Yang, Hong Zhao

“…Therefore, attention should be paid to the dietary habits and nutritional status of patients with depression or depressive symptoms when they are undergoing long-term antidepressant treatment. Folic acid supplementation is recommended for patients with moderate or severe depression or for depressed patients who have developed unhealthy eating habits.…”
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Effect of Parental Migration Background on Childhood Nutrition, Physical Activity, and Body Mass Index by Mohsen Besharat Pour, Anna Bergström, Matteo Bottai, Inger Kull, Magnus Wickman, Niclas Håkansson, Alicja Wolk, Tahereh Moradi

“…They had higher intake of dietary fibre, vitamins C, B6, and E, folic acid, and polyunsaturated fatty acids (omega-3 and omega-6) reflecting higher consumption of foods of plant origin, but lower intake of vitamins A and D, calcium, and iron reflecting lower consumption of dairy products. …”
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Enhancing the growth and essential oil components of Lavandula latifolia using Malva parviflora extract and humic acid as biostimulants in a field experiment by Mervat El-Hefny, Mahmoud Khattab Hussien

“…The most prevalent vitamins found in ME were vitamin B12, vitamin C, and folic acid. Besides, several phenolic compounds were found in ME, such as catechol, cinnamic acid and syringic acid, while flavonoid chemicals, such as luteolin and quercetin. …”
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Modification of Platelet Count on the Association between Homocysteine and Blood Pressure: A Moderation Analysis in Chinese Hypertensive Patients by Jianan Zhang, Jing Li, Shi Chen, Linglin Gao, Xiaoluan Yan, Mingzhi Zhang, Jia Yu, Fenchun Wang, Hao Peng

“…Platelet count has been found to modify the effect of folic acid on vascular health. However, whether platelet count could modify the contribution of homocysteine to blood pressure (BP) remains unclear. …”
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Multivitamin Supplementation and Fertility Outcome: A Retrospective Single-Center Cohort Study and the Clinical and Medicolegal Value of Nutritional Counseling by Giuseppe Gullo, Simona Zaami, Adriana Vita Streva, Sofia Burgio, Valentina Billone, Yulia Kotlik, Elena Chitoran, Silvia Ganduscio, Giovanni Baglio, Antonio Perino, Gaspare Cucinella

“…The study group underwent pre-treatment with a daily nutraceutical based on resveratrol, whereas the control group received 400 mcg/day of folic acid. Primary endpoints to be evaluated were the number of mature follicles developed (>16 mm), total oocytes and Metaphase II (MII) oocytes retrieved, fertilization rate, number of embryos/blastocysts obtained, and semen quality. …”
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Recurrent syncope after hysteroscopy finally diagnosed as cerebral venous sinus thrombosis: a case report by Yongqing Zhang, MD, Hongxing Ye, MD, Danqing Chen, MD, PhD, Guohui Yan, MD, Zhanfu Li, MD, Qianhui Xie, MD, Guodong Shan, MD, Zhaoxia Liang, MD, PhD

“…Treatment with anticoagulants, folic acid, and vitamin B6 led to a favorable outcome. …”
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Folate Intake and Markers of Folate Status in Women of Reproductive Age, Pregnant and Lactating Women: A Meta-Analysis by Cristiana Berti, Katalin Fekete, Carla Dullemeijer, Monica Trovato, Olga W. Souverein, Adriënne Cavelaars, Rosalie Dhonukshe-Rutten, Maddalena Massari, Tamás Decsi, Pieter van't Veer, Irene Cetin

“…To assess the dose-response relationship between total folate intake (folic acid plus dietary folate) and markers of folate status (plasma/serum folate, red blood cell folate, and plasma homocysteine); to evaluate potential differences between women in childbearing age, pregnant and lactating women. …”
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Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials by Sumera Aziz Ali, Jeanine Genkinger, Ka Kahe, Linda Valeri, Nayab Khowaja, Nancy F. Krebs, Louise Kuhn

“…Preconception nutrition supplements (iron and folic acid, multiple micronutrients, and a lipid-based nutrient supplement) overall increased maternal hemoglobin by 0.30 g/dL ((0.03, 0.57); I 2 = 79%; n=9). …”
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Сlinical case of funicular myelosis in combination with a concomitant genetic predisposition to folate cycle disorder by O.D. Shulga, E.A. Popko, A.S. Chabanova, O.G. Kotsiuba, Q. Hussain

“…And when detecting hyperhomocysteinemia, it is advisable to take into account other factors that can cause an increase in the level of homocysteine, in addition to a deficiency of vitamins B6, B12 and folic acid.…”
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Genetic-epigenetic aspects of infertility in women with long-COVID-19 by O.G. Boichuk, I.S. Golovchak, T.V. Kolomiichenko

“…The genetic and epigenetic conditioning of the success of ART programs in infertility associated with long-term COVID-19 has been revealed, which opens up new diagnostic and therapeutic opportunities for identifying factors predisposing to unsuccessful ART treatment and increasing the effectiveness of such treatment by correcting disorders of folic acid metabolism, hyperhomocysteinemia and the estrogens receptor apparatus. …”
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Gene Therapy for Inflammatory Cascade in Intrauterine Injury with Engineered Extracellular Vesicles Hybrid Snail Mucus‐enhanced Adhesive Hydrogels by Xiaotong Peng, Tao Wang, Bo Dai, Yiping Zhu, Mei Ji, Pusheng Yang, Jiaxin Zhang, Wenwen Liu, Yaxin Miao, Yonghang Liu, Shuo Wang, Jing Sun

“…First, inspired by the high bio‐adhesion capacity of SM, SM and gelatin methacrylate (GelMA) solution are mixed to construct GelMA/SM (GS) hydrogel. Then, folic acid‐modified extracellular vesicles (FA‐EVs) are synthesized for targeting the delivery of STAT1‐siRNA. …”
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