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  1. 5661

    Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

    Published 2025-01-01
    “…Elevated cerebrospinal fluid (CSF) levels of CHI3L1 have been linked to disease severity and cognitive decline, particularly in AD and MS, highlighting its potential for clinical diagnostics. …”
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  2. 5662

    白三烯受休拈抗剂孟鲁斯特对小鼠气道炎症的抑制作用 by 李雯

    Published 2005-01-01
    “…【方法}致敏的BALB/c小鼠待续吸入10叭L雾化卯白蛋白(OVA)30 111in,OVA吸入前2d开始连续3cl 或5J尾静脉给予MK或生理盐水(saline),OVA吸入后24h及72h取材,瑞氏染色观察支气管肺泡泄洗液 (bronchoalveolar lavage fluid, BALF)中炎症细胞的渗出情汜ELISA方法检测血清、BALF和肺组织中有关细胞因子水平;HE、刚果红染色观察肺组织炎症细胞的渗出;免疫组化染色观察血管内皮细胞黏附分子-l(VCAM-1)和 嗜酸性粒细胞趋化因子(eot,ixin)的表达,原位杂交研究IL-5mRNA的变化,[绪果】给予MK5 d减少BALF嗜 酸性粒细胞渗出达90%以上,嗜酸性粒细胞减少随MK剂量(10、25、62.5mg/kg)的增加呈显效关系。…”
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  3. 5663

    Serum Inflammatory Cytokines and Growth Factors in Patients with Sjögren’s Syndrome and Diabetes Mellitus by Yalçın Karaküçük, Sema Yilmaz, Ali Unlu, Banu Bozkurt, Şule Nur Acar Duyan

    Published 2023-08-01
    “…Therefore, autologous serum seems to be a good option to replace deficient tear fluid in these subjects.…”
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  4. 5664
  5. 5665

    Anti-Inflammatory Effect Fraction of Bletilla striata and Its Protective Effect on LPS-Induced Acute Lung Injury by Chunchun Zhang, Dandan Ning, Jieli Pan, Cheng Chen, Chengxian Gao, Zhishan Ding, Fusheng Jiang, Meiya Li

    Published 2021-01-01
    “…Pretreatment with the EFBS (20 mg/kg and 60 mg/kg) for five days prior to the administration of LPS resulted in decreases in wet-to-dry lung weight ratio, neutrophil number, MPO activity, total protein concentration, NO level, and MDA level, as well as IL-1β, IL-6, MCP-1, and TNF-α concentrations in the bronchoalveolar lavage fluid. Western blot analysis demonstrated the increased expressions of iNOS, COX-2, and NF-κB p65 in the LPS treatment group, all of which were ameliorated by EFBS pretreatment. …”
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  6. 5666

    Efficacy and safety of faricimab for neovascular age-related macular degeneration: a systematic review and network meta-analysis by Francisco Rodríguez, Daniel Samacá-Samacá, Claudia Hernández-Castillo, Laura Prieto-Pinto, Carolina Sardi, Hugo Ocampo, Joshua Kock, Fabián Hernández

    Published 2024-05-01
    “…Results also showed that more patients treated with faricimab were free from post-treatment retinal fluid compared with aflibercept every 8 weeks, and both ranibizumab and bevacizumab, in the fixed and pro re nata (PRN) assessed schedules. …”
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  7. 5667

    Anti-VEGF agents for the treatment of diabetic macular edema by S.G. Sergushev, E.N. Khomyakova

    Published 2019-11-01
    “…This paper also describes in detail post-hoc analyses of VIVID/VISTA studies on the efficacy of aflibercept in patients with or without subretinal fluid at baseline, patients with uncontrollable diabetes, and previously treated patients. …”
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  8. 5668

    Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study by Md. Jubayer Hossain, Manisha Das, Muhibullah Shahjahan, Md. Wahidul Islam, Syeda Tasneem Towhid

    Published 2025-01-01
    “…Severe cases involve critical plasma leakage, leading to DSS with fluid accumulation, respiratory distress, and potential multiorgan involvement. …”
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  9. 5669
  10. 5670

    Parametric analysis on the transient two-phase wellbore model applied to the Yangyi high-temperature geothermal field by Chaofan Chen, Hongwei Zhou, Thomas Nagel, Theo Renaud, Dmitri Naumov, Olaf Kolditz, Haibing Shao

    Published 2025-01-01
    “…The flash point location in the wellbore moves upwards for 112 m along with the decrease in fluid enthalpy by 200 kJ/kg. In the wellbore shut-in process, the wellhead pressure decreases with decreasing velocity, while the location of the flash point does not change much. …”
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  11. 5671

    Luteolin Regulates the Differentiation of Regulatory T Cells and Activates IL-10-Dependent Macrophage Polarization against Acute Lung Injury by Ke Xie, Yu-sen Chai, Shi-hui Lin, Fang Xu, Chuan-jiang Wang

    Published 2021-01-01
    “…The levels of Treg-related cytokines in serum and bronchoalveolar lavage fluid (BALF) of mice were detected. The protein levels of NF-κB p65 in lung tissues were measured. …”
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  12. 5672

    Gemelos digitales pulmonares by Ana Fernández-Tena, Carlos Arnedo, Guillaume Houzeaux, Beatriz Eguzkitza

    Published 2024-10-01
    “…DTs integrate clinical data, high-resolution images, and mathematical models to simulate respiratory mechanics, gas diffusion, and fluid dynamics in real time. This technology improves diagnosis, treatment planning, and disease progression monitoring. …”
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  13. 5673

    Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p by Wei Peng, Yun Yang, Jiaquan Chen, Zeyao Xu, Yuanlei Lou, Qi Li, Ning Zhao, Kejian Qian, Fen Liu

    Published 2023-01-01
    “…The efficacy of iMSC-sEV was assessed by histology, immunohistochemistry, and pro-inflammatory cytokines of bronchoalveolar lavage fluid. We also evaluated the in vitro effects of iMSC-sEV on the activation of the inflammatory response in alveolar macrophages (AMs). …”
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  14. 5674

    Colonic cytokines for severe ulcerative colitis by Ye. A. Konovich, K. Ye. Shirokikh, I. L. Khalif, M. V. Shapina

    Published 2016-08-01
    “…Cytokine concentration was evaluated in supernatant fluid after centrifugal separation of 10 mg biopsy specimen homogenate by the protein analyzer «Bio-Plex» («Bio-Rad», USA). …”
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  15. 5675

    Analysis of risk factors for acute cerebral infarction in patients with intracranial tuberculosis by Xiao-Shan Huang, Xiao-Wei Qiu, An-Long Wang, Fei He, Yi-Jing Wang

    Published 2025-01-01
    “…Clinical data, cerebrospinal fluid (CSF) examinations, and imaging features (such as hydrocephalus, cerebral arteritis, and meningeal thickening) were compared between the two groups. …”
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  16. 5676

    Enhance Oil Recovery in Fracture-Cave Carbonate Reservoirs Using Zwitterion-Anionic Composite Surfactant System by Wei Peng, Qing You, Xiaoqiang Liu, Bojie Zhou, Xingxing Ding, Yuechun Du, Liangfei Xiao

    Published 2025-01-01
    “…High-pressure injection flooding technology is an innovative method that utilizes injection pressure higher than the formation rupture pressure to alter reservoir permeability, specifically in low-permeability oil fields. Because of the high fluid flow rate, the contact time with the interface is decreased, enabling the ability for surfactants to reach the deep reservoir. …”
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  17. 5677

    Using diagnostic data from veterinary diagnostic laboratories to unravel macroepidemiological aspects of porcine circoviruses 2 and 3 in the United States from 2002-2023. by Guilherme Cezar, Edison Magalhães, Kinath Rupasinghe, Srijita Chandra, Gustavo Silva, Marcelo Almeida, Bret Crim, Eric Burrough, Phillip Gauger, Christopher Siepker, Marta Mainenti, Michael Zeller, Eduardo Fano, Pablo Piñeyro, Rodger Main, Mary Thurn, Paulo Lages, Cesar Corzo, Albert Rovira, Hemant Naikare, Rob McGaughey, Franco Matias-Ferreyra, Jamie Retallick, Jordan Gebhardt, Jon Greseth, Darren Kersey, Travis Clement, Angela Pillatzki, Jane Christopher-Hennings, Melanie Prarat, Ashley Johnson, Dennis Summers, Craig Bowen, Joseph Boyle, Kenitra Hendrix, Andreia G Arruda, Daniel Linhares, Giovani Trevisan

    Published 2024-01-01
    “…Findings indicated a decrease in the percentage of PCV2-positive submissions after introducing a commercial PCV2 vaccine in 2006 and a resurgence in positivity after 2018, particularly in breeding herds, associated with an increased number of submissions using processing fluid samples. After its first report in the U.S. in 2016, PCV3 detection had an upward trend in the percentage of positive cases, peaking in spring 2023. …”
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  18. 5678

    Comparison of Crushed-Zone Skin Factor for Cased and Perforated Wells Calculated with and without including a Tip-Crushed Zone Effect by Ekhwaiter Abobaker, Abadelhalim Elsanoose, Faisal Khan, Mohammad Azizur Rahman, Amer Aborig, Stephen Butt

    Published 2021-01-01
    “…The experimental test was carried out using a geotechnical radial flow set-up to measure the differential pressure in the perforation tunnel with a crushed zone. Computational fluid dynamics (CFD) software was used for simulating pressure gradient in a cylindrical perforation tunnel. …”
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  19. 5679

    A descriptive analysis of a medical humanitarian aid initiative for quality perinatal management in war-torn Ukraine by Iryna Mogilevkina, Dmytro Dobryanskyy, Rhona MacDonald, Diane Watson, David Southall

    Published 2025-02-01
    “…In the staff plus mother group, more often lateral tilt, intravenous fluid, spontaneous vaginal and vacuum assisted delivery and less often caesarean sections were undertaken even when fetal distress alone was an indication for operative delivery at term pregnancy. …”
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  20. 5680