Low-dose radiation ameliorates PM2.5-induced lung injury through non-canonical TLR1/TLR2-like receptor pathways modulated by Akkermansia muciniphila by Li Wang, Zhipeng Li, Huan He, Lijing Qin, Weiqiang Xu, Hongyuan Tian, Rongrong Liu, Xinru Lian, Wen Li, Yali Qi, Zhicheng Wang

“…Additionally, after PM2.5 exposure, M1 polarization of macrophages in alveolar lavage fluid and Th1 polarization in spleen increased, pro-inflammatory cytokines (IL-1, IL-6 and TNF-α) increased and anti-inflammatory cytokines (IL-4, IL-10 and TGF-β) decreased in lung and serum. …”
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Artificial intelligence-driven fuzzy logic approach for optimal well selection in gas lift design: A brown field case study by Nnaemeka Princewill Ohia, Chadi Paul, Emmanuel Asolo, Taiwo Adetomiwa Adewa, Chidimma Favour Chukwu, Paschal Ateb Ubi, Daniel Hogan Itam, Daniel Ugochukwu Nnaji

“…Given the need for a more flexible and accurate well selection process, the Mamdani type-2 fuzzy logic model was employed in this study to address the high levels of imprecision associated with key production parameters, including Gas-Oil Ratio (GOR), Barrel of Oil Produced per Day (BOPD), Basic Sediment and Water (BS&W), Barrel of Fluid Produced per Day (BFPD), Gas Produced (MCFPD), Total Gas-Liquid Ratio (TGLR), Tubing Pressure (TBG PR), and Manifold Pressure (MNFLD PR). …”
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Nano-delivery platform with strong protection and efficient delivery: preparation of self-assembled RNA pesticide with dual RNAi targets against Apolygus lucorum by Heng Qiao, Qinhong Jiang, Jing Zhao, Liubin Xiao, Keyan Zhu-Salzman, Dejin Xu, Guangchun Xu, Jie Shen, Aiguo Gu, Dejun Hao, Shuo Yan, Yongan Tan

“…The SPc could protect the dsRNA from the degradation by midgut fluid or RNase A, thus significantly increasing the stability of dsRNA under various environmental conditions. …”
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Prolidase activity in women with polycystic ovarian syndrome undergoing assisted conception by Kadriye Erdoğan, Emine Utlu Özen, İnci Kahyaoğlu, Salim Neselioglu, Özcan Erel, Serra Akar, Özhan Özdemir, Cihangir Mutlu Ercan, Yaprak Engin Üstün

“…This study aimed to examine prolidase activity in the serum and follicular fluid (FF) of women undergoing in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) treatment, comparing those with PCOS to those with normal ovarian function.Methods This prospective study enrolled 50 participants, of whom 44 were included. …”
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The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury by Xiao Zhao, Han Han, Yinting Song, Mei Du, Mengyu Liao, Xue Dong, Xiaohong Wang, Ferenc Kuhn, Annette Hoskin, Heping Xu, Hua Yan

“…Ranibizumab or Conbercept was injected into the vitreous at 0.5 hours, 3 days, or 7 days. Vitreous fluid was collected, and levels of growth factors and cytokines were measured by enzyme-linked immunosorbent assay (ELISA). …”
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Adverse outcome pathway-based assessment of pulmonary toxicity from the in vivo mixture of biocides dinotefuran and cetylpyridinium chloride by Yoon Cho, Mi-Kyung Song, Dong Im Kim, Min-Seok Kim, Kyuhong Lee

“…Various parameters, including clinical and histopathological indicators, changes in body weight and organ weight, inflammatory cell distribution, and inflammatory cytokine expression in the bronchoalveolar lavage fluid (BALF), were analyzed. Additionally, key indicators such as TLR4, NF-κB, TNF-α were investigated to validate the mechanistic aspects of putative AOPs associated with pulmonary fibrosis. …”
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Monitoring M-Protein, Therapeutic Antibodies, and Polyclonal Antibodies in a Multiparametric Mass Spectrometry Assay Provides Insight into Therapy Response Kinetics in Patients wit... by Charissa Wijnands, Peter G. A. Karel, Jolein Gloerich, Gad Armony, Anastasia Tzasta, Corrie M. de Kat Angelino, Luciano Di Stefano, Vincent Bonifay, Theo M. Luider, Martijn M. VanDuijn, Sandra J. Croockewit, Elizabeth A. de Kort, Daan A. R. Castelijn, Claudia A. M. Stege, Hans J. C. T. Wessels, Alain J. van Gool, Niels W. C. J. van de Donk, Joannes F. M. Jacobs

“…<b>Methods:</b> Sera collected between 2013 and 2024 from four patients and cerebrospinal fluid (CSF) from one patient who received various t-Abs were analyzed with MS-MRD. …”
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Natural pigments: innovative extraction technologies and their potential application in health and food industries by Ayu Masyita, Gemala Hardinasinta, Ayun Dwi Astuti, Firdayani Firdayani, Dian Mayasari, Aki Hori, Ira Nur Ainun Nisha, Firzan Nainu, Takayuki Kuraishi

“…Special emphasis is placed on emerging technologies for natural pigment extraction (thermal technologies, non-thermal technologies, and supercritical fluid extraction), their pharmacological effects, and their potential application in intelligent food packaging and as food colorants. …”
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A novel virulent core genome multilocus sequence type CT 11424 of Listeria monocytogenes isolate causing stillbirth in Bangladesh by Muntasir Alam, Md Saiful Islam, M. Ishrat Jahan, Arpita Shyama Deb, Afruna Rahman, Zahidul Islam, Atique Iqbal Chowdhury, Kazi Munisul Islam, Mohammad Zahid Hossain, Dilruba Ahmed, Shams El Arifeen, Emily S. Gurley, Mustafizur Rahman

“…The Lm-BD-CHAMPS-01 isolate was recovered from the blood and cerebrospinal fluid (CSF) of a male stillborn. Maternal history, clinical, and demographic data were collected by the CHAMPS surveillance platform. …”
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Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease by Giorgos Bamias, Michalis Gizis, Ioanna Delladetsima, Eyfrosyni Laoudi, Spyros I. Siakavellas, Ioannis Koutsounas, Garyfallia Kaltsa, John Vlachogiannakos, Irene Vafiadis-Zouboulis, George L. Daikos, George V. Papatheodoridis, Spiros D. Ladas

“…In addition, DcR3 protein was detected in large quantities in the ascitic fluid of cirrhotics. In patients with CVH, sDcR3 significantly correlated to fibrosis severity, as estimated by Ishak score (P=0.019) or by liver stiffness measured with elastography (Spearman r=0.698, P<0.001). …”
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Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D by Yang Qin, Li Liu, Yanwen Zhang, Xiaowei Chen, Jiani Zhang, Sunwang Ling, Jianguang Wang, Xinyu Yang

“…Autoantibodies against citrullinated IGF2BP1 are further detected in serum and synovial fluid samples from RA patients, which are positively correlated with erythrocyte sedimentation rate (ESR) and disease activity score 28 (DAS28). …”
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Ensiling and thermic treatment effects on ruminal carbohydrate fermentation and post-ruminal crude protein concentration in partial-crop peas and faba beans by M. Bachmann, P. Okon, F. Pilger, C. Kuhnitzsch, S.D. Martens, O. Steinhöfel, A. Zeyner

“…This study was conducted to examine effects of ensiling, toasting or ensiling plus toasting in partial-crop field peas and faba beans harvested each with 375 g dry matter/kg (Biologische Bundesanstalt, Bundessortenamt und Chemische Industrie (BBCH) scale 79 and 81, respectively) on gas production and post-ruminal crude protein (PRCP) concentration by in vitro incubation in ruminal fluid batch-cultures. The silages made from partial-crop field peas and faba beans (Rostock Model Silages) had a pH of 4.3 and 4.6, respectively, and were not typically lactic acid dominated. …”
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M. A. Fedorova, M. W. Tofique, A. Löf, C. Millward, Z. Günther. Testing and calculation of impact fatigue strength of Flap-X and SS 716 flapper valve steel grades / trans from Engl... by M. A. Fedorova

“…During the operation of reciprocating compressors, the flapper valve opens and closes under fluid pressure and flow. As it closes, it strikes against the valve seat, generating stresses and noise. …”
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Microvascular decompression: a contemporary update by Inibehe Ime Okon, Sidharth Sunil Menon, Mahmoud Osama, Maidan Aiman, Luis F. Fabrini Paleare, Don Lucero-Prisno Eliseo, Muhammad Danish Shafqat, Chizowa Okwuchukwu Ezeaku, Márcio Yuri Ferreira, Youssef Razouqi, Marianna Kapsetaki, Jovy Dia Remolino Saniel, Naneta M. Panit, Asad Gul Rao, Umer Iqbal, Daniel David Otobo, Ibraheem M. Alkhawaldeh, Felipe Salvagni Pereira, Imad Akbar, Omar Kasimieh, Bipin Chaurasia

“…Despite these advancements, complications such as hearing loss (1–2%) and cerebrospinal fluid leakage (2–4%) persist, highlighting the need for continuous refinement of techniques. …”
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Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution by Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F. Joos, Guy G. Brusselle, Tania Maes

“…We previously demonstrated that concurrent exposure to house dust mite (HDM) and DEP in mice increases both eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) and also results in higher levels of neutrophil-recruiting chemokines and neutrophil extracellular trap (NET) formation compared to sole HDM, sole DEP or saline exposure. …”
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Effects of in-ovo injection of Yu ping feng polysaccharides on growth performance, intestinal development, and immunity in broiler chickens by Li-Gang Xue, Tian-Kui Guo, Juan Wang, Yu-Quan Shan, Li Guo, Dong-Xing Zhang, Zhong Wei, Dan Wang

“…Furthermore, the YPF group exhibited a statistically significant increase in intestinal IgA+ cell count and flushing fluid SIgA level throughout various time periods compared with those in the other three groups. …”
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Clinical effect analysis of posterior longitudinal ligament resection during anterior cervical discectomy and fusion in the treatment of cervical spondylotic myelopathy by NIU Hai‐ying, MENG Xiang‐yu, ZUO Shan‐shan, SUN Xiao‐li, LI Yan, LIU Hong‐lei

“…There were 30 patients (78.95%) experienced transient symptoms, including dysphagia, pharyngeal pain and drinking cough, 15 patients (39.47%) reported symptoms of hoarseness, 3 patients (7.89%) experienced a transient decrease in muscle strength in the left upper limb, and one patient (2.63%) had cerebrospinal fluid leakage. Notably, no patients exhibited incomplete healing of the incision or infection. …”
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Different Activity of the Biological Axis VEGF-Flt-1 (fms-Like Tyrosine Kinase 1) and CXC Chemokines between Pulmonary Sarcoidosis and Idiopathic Pulmonary Fibrosis: A Bronchoalveo... by Katerina M. Antoniou, Giannoula Soufla, Athanasia Proklou, George Margaritopoulos, Christiana Choulaki, Rena Lymbouridou, Katerina D. Samara, Demetrios A. Spandidos, Nikolaos M. Siafakas

“…We estimated the levels of vascular endothelial growth factor (VEGF) and its high-affinity receptor, Flt-1 (fms-like tyrosine kinase 1), in bronchoalveolar lavage fluid (BALF) of patients with IPF and pulmonary sarcoidosis. …”
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Efficacy and Safety of HAPC in Barrett's Esophagus – A Multicenter Italian Prospective Study by Davide Massimi, Roberta Maselli, Silvia Pecere, Cristiano Spada, Gianluca Andrisani, Francesco Maria Di Matteo, Antonella La Terra, Franco Coppola, Antonio Capogreco, Roberto De Sire, Ludovico Alfarone, Maddalena Menini, Marco Spadaccini, Cesare Hassan, Alessandro Repici

“…Hybrid argon plasma coagulation (H-APC) is a novel technique for the ablation of neoplastic Barrett Esophagus (BE), consisting in submucosal fluid injection and subsequent APC of visible BE. …”
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Quality of Life Philosophy III. Towards a New Biology: Understanding the Biological Connection between Quality of Life, Disease, and Healing by Soren Ventegodt, Niels Jørgen Andersen, Joav Merrick

“…If a cell is seen as a liquid crystal in which the cell’s molecules constantly connect in firm mutual relationships only to dissolve again and become fluid and free, whenever the cell needs it, the backbone of the cell seems to be the information that organizes the cell. …”
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