Factors Controlling the Hydraulic Fracture Trajectory in Unconventional Reservoirs by Peng Zheng, Erhu Liu, Desheng Zhou, Xinwei Du, Zhongjun Ma

“…Hydraulic fracture deflection angle was relatively larger when considering the viscosity of the fracturing fluid. When stress difference is too small or the injection pressure is too big, the deflection angle of fracture is easy to fluctuate during initial propagation. …”
Get full text

Experimental Research on Heating Transfer Improvement of Materials that Change Phase in Tunnels in Cold Regions by Xu Zhang, Dianwei Qi, Wanjiang Wang, Jiaqi Zhang, Hongchao Yan, Xiancheng Li

“…Experiments were performed out in order to determine the effects of heating rate, hot fluid flow rate, and the use of a spiral metal ring on the heat storage and release process of a thermal storage device. …”
Get full text

Near-Field Aeroacoustics of Spanwise Forcing on a Transonic Wing: A DNS Study by Niccolò Berizzi, Davide Gatti, Giulio Soldati, Sergio Pirozzoli, Maurizio Quadrio

Get full text

Effect of V-Shaped Groove Microstructure on Blood Flow Resistance in Bionic Artificial Blood Vessels by Zhou Li, Yunqing Gu, Lingzhi Yu, Zhuofan Yin, Wenting Wang, Denghao Wu, Jiegang Mou, Shuihua Zheng

Get full text

Social and Cultural Integration: A Discourse Analysis of Islamic Themes in the Basis Magazine, 1998–2000 by Rhoma Dwi Aria Yuliantri

“…The Islamic discourse in Basis demonstrated a fluid nature, suggesting coexistence and close interaction among adherents of various value systems and worldviews.…”
Get full text

A 16-Year-Old Male with Thoracic Compression following Posterior Spinal Instrumentation and Fusion for Marfan-Associated Syndromic Scoliosis by Mason Uvodich, Ross Barman, Adam Reitz, Matthew Sexton

“…The patient had a complicated perioperative course requiring significant fluid resuscitation and vasoactive medications to support blood pressure. …”
Get full text

Formation Mechanism of Preferential Flow Paths and Seepage Characteristics of a Novel Growable Pile for Heap Leaching of Rare Earth by Wei Ju, Jianhua Yang, Zemin Wang, Chi Yao, Xiaobo Zhang

“…The preferential flow paths are mainly distributed in the lower part of the pile near the liquid injection end. This causes the fluid in the lower part of the pile to seep faster significantly than that in the upper part. …”
Get full text

3D bioprinting lobule-like hepatorganoids with induced vascularization for orthotopic implantation by Jianing Yan, Zhichao Ye, Yiwei Lu, Yuyang Yuan, Xiaofeng Wang, Tingting Yan, Jun Yin, Yifan Wang

Get full text

The first experience with brolucizumab for neovascular age-related macular degeneration by A.N. Kulikov, D.S. Maltsev, A.Yu. Malafeeva, S.M. Perminova, V.R. Zhalimova, A.S. Vasiliev, A.A. Kazak

“…BCVA, central macular thickness (CMT), macular volume (MV), sub/intraretinal fluid, and adverse events were evaluated.</i> </p> <p> <i><b>Results</b>: in group 1, a significant increase in BCVA from 34.9±6.6 letters to 44.1±4.2 letters (p=0.02) was reported. …”
Get full text

Neostigmine Attenuates Proinflammatory Cytokine Expression in Preoptic Area but Not Choroid Plexus during Lipopolysaccharide-Induced Systemic Inflammation by Andrzej P. Herman, Dorota Tomaszewska-Zaremba, Marta Kowalewska, Aleksandra Szczepkowska, Małgorzata Oleszkiewicz, Agata Krawczyńska, Maciej Wójcik, Hanna Antushevich, Janina Skipor

“…The study was designed to examine whether the administration of neostigmine (0.5 mg/animal), a peripheral inhibitor of acetylcholinesterase (AChE), during an immune/inflammatory challenge provoked by intravenous injection of bacterial endotoxin—lipopolysaccharide (LPS; 400 ng/kg)—attenuates the synthesis of proinflammatory cytokines in the ovine preoptic area (POA), the hypothalamic structure playing an essential role in the control of the reproduction process, and in the choroid plexus (CP), a multifunctional organ sited at the interface between the blood and cerebrospinal fluid in the ewe. Neostigmine suppressed (p<0.05) LPS-stimulated synthesis of cytokines such as interleukin- (IL-) 1β, IL-6, and tumor necrosis factor (TNF) α in the POA, and this effect was similar to that induced by the treatment with systemic AChE inhibitor—donepezil (2.5 mg/animal). …”
Get full text

Design and application of a novel device for recovering and storing gastric juices (一种新型胃液回收及存储装置的设计与应用) by WANG Weiwei (王伟伟), ZHANG Meng (张萌), SUN Xiumei (孙秀梅)

“…This paper introduces the design and use method of a utility model gastric fluid recovery and storage device, which can effectively reduce the occurrence of secondary pollution, reduce the work burden of medical staff and improve work efficiency. …”
Get full text

Acute Renal Replacement Therapy in Children with Diarrhea-Associated Hemolytic Uremic Syndrome: A Single Center 16 Years of Experience by Silviu Grisaru, Melissa A. Morgunov, Susan M. Samuel, Julian P. Midgley, Andrew W. Wade, James B. Tee, Lorraine A. Hamiwka

“…The most common recorded complications in our cohort were peritoneal fluid leaks 13 (22%), peritonitis 11 (20%), and catheter malfunction 5 (9%). …”
Get full text

Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case re... by Xuelian Jin, Xushu Zhong, Qinyu Liu, Xinchuan Chen

“…She received five courses of 100 mg every 4 weeks with monitoring by magnetic resonance imaging (MRI) and viral load in the cerebrospinal fluid, showing clinical improvement, resolution of neurological symptoms, and reduced viral load. …”
Get full text

Ischemic colitis presenting as a colonic mass: a case report and diagnostic challenges by Lin Xu, Yuqi Wu, Yuqi Wu, Shangjin Li, Shangjin Li, Xinbo Chen, Dong Zhang, Boqian Chen, Shaoju Guo

“…Initially diagnosed with IC, the patient’s symptoms gradually improved with conservative treatment, which included antibiotics, fluid resuscitation, and bowel rest. Follow-up endoscopy showed significant lesion improvement, and no recurrence was detected during subsequent follow-ups. …”
Get full text

An Investigation of the Basic Physics of Irrigation in Urology and the Role of Automated Pump Irrigation in Cystoscopy by Dwayne Chang, Rustom P. Manecksha, Konstantinos Syrrakos, Nathan Lawrentschuk

“…To investigate the effects of height, external pressure, and bladder fullness on the flow rate in continuous, non-continuous cystoscopy and the automated irrigation fluid pumping system (AIFPS). Materials. Each experiment had two 2-litre 0.9% saline bags connected to a continuous, non-continuous cystoscope or AIFPS via irrigation tubing. …”
Get full text

Developing non-invasive molecular markers for early risk assessment of Alzheimer's disease by Tapas K. Sur, Tanmoy Mondal, Zarish Noreen, Jheannelle Johnson, Gail Nunlee-Bland, Christopher A. Loffredo, Brent E. Korba, Vijay Chandra, Siddhartha S. Jana, Bernard Kwabi-Addo, Sumit Sarkar, Somiranjan Ghosh

“…Current improvements have unveiled the disease's pathophysiology and clinical diagnostic tests, targeting the neurological changes (neurodegeneration, amyloid precursor protein metabolism and tangle pathology) with precise PET/MRI imaging and xMAP/SIMOA (Multiplex simultaneous detection/single molecule array) to identify and quantify β-amyloids (Aβ40, Aβ42), total tau (T-tau) and phosphorylated tau (P-tau) proteins in the brain and cerebrospinal fluid (CSF) of patients. However, their utility for diagnosis in routine clinical practice is still challenging because of cost, accessibility, standardization, procedural limitation, and regulatory approval. …”
Get full text

β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…Our comprehensive analysis of the molecular landscape surrounding the trauma in TBI mice has revealed a significant alteration in the abundance of β2 integrin (ITGB2), predominantly expressed by neutrophils and closely associated with immune responses. Using the fluid percussion injury (FPI) mouse model, we investigated the therapeutic efficacy of Rovelizumab, an agent that blocks ITGB2. …”
Get full text

Implications of entropy generation in bioconvective flow on Maxwell nanofluid past a Riga plate with Cattaneo--Christov model by K. Loganathan, Prasun Choudhary, S. Eswaramoorthi, K. Senthilvadivu, N. Thamaraikannan, Reema Jain

“…This study explores the effects of heat and mass transfer in the flow of Maxwell nanofluid over a heated Riga plate. The fluid contains nanoparticles and gyrostatic microorganisms. …”
Get full text

VOF Modeling and Analysis of the Segmented Flow in Y-Shaped Microchannels for Microreactor Systems by Xian Wang, Hiroyuki Hirano, Gongnan Xie, Ding Xu

“…The segment length was studied. The volume of fluid (VOF) method was used to track the liquid-liquid interface and the piecewise-liner interface construction (PLIC) technique was adopted to get a sharp interface. …”
Get full text

Flow Characteristics and Experimental Verification of T-Groove Dry Gas Seal Under Different Flow States by Lanxia Zhang, Xuexing Ding, Shipeng Wang, Shuai Zhang

“…In addition, the inertia effect improved, which slowed down the leakage and affected the change law of stiffness and the rigid leakage ratio. When the fluid speed and gas pressure were low, the inertia effect could be ignored. …”
Get full text