Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits by Yiying Hu, Alexander Hruscha, Chenchen Pan, Martina Schifferer, Michael K. Schmidt, Brigitte Nuscher, Martin Giera, Sarantos Kostidis, Özge Burhan, Frauke van Bebber, Dieter Edbauer, Thomas Arzberger, Christian Haass, Bettina Schmid

“…RNA sequencing was used to identify mis-regulated pathways with validation by molecular analysis. Results CytoTDP fish have early larval phenotypes resembling clinical features of ALS such as progressive motor defects, neurodegeneration and muscle atrophy. …”
Get full text

Bladder-sparing therapy in a case report of huge muscle-invasive bladder IMT treated with 1470 nm diode laser en bloc resection followed by laparoscopic partial cystectomy by Junhao Chu, Huisheng Yuan, Zhihui Zhang, Jiajun Kan, Shishuai Duan, Zilong Wang, Zilong Wang, Zilong Wang, Muwen Wang

“…Pathological examination following 1470 nm laser resection confirmed the diagnosis of an IMT with malignant potential, showing anaplastic lymphoma kinase (ALK) positivity, a Ki-67 index of 20% in hotspot regions, and ALK gene rearrangement detected by fluorescence in situ hybridization (FISH). Pathology after the secondary laparoscopic partial cystectomy showed tumor invasion into the superficial muscle layer, with negative margins at the resection site. …”
Get full text

Woody Species Structure and Regeneration Status in Kafta Sheraro National Park Dry Forest, Tigray Region, Ethiopia by Fitsum Temesgen, Bikila Warkineh

“…., Hippotragus equinus, Anthropoides virgo, Ourebia ourebi, Crocuta crocuta, Tragelaphus strepsiceros, Phacochoerus africanus, and unidentified crocodile and fish species. In the park, the vegetation ecology has not been studied up to date which is necessary for conservation. …”
Get full text

Salinity stress-induced impacts on biomass production, bioactive compounds, antioxidant activities and oxidative stress in watermeal (Wolffia globosa) by Nitesh Kumar Yadav, Arun Bhai Patel, Himanshu Priyadarshi, Sampa Baidya

Get full text

Shotgun metagenomics reveals the interplay between microbiome diversity and environmental gradients in the first marine protected area in the northern Arabian Gulf by Saja A. Fakhraldeen, Rakhesh Madhusoodhanan, Nazima Habibi, Sakinah Al-Haddad, Surendraraj Alagarsamy, Sabeena F. K. Habeebullah, Walid M. Al-Zakri, Fathima Thuslim, Loreta Fernandes, Faiza Al-Yamani, Turki Al-Said

“…IntroductionThe northwest Arabian Gulf encounters significant anthropogenic pressures, including nutrient enrichment from coastal development and effluent discharge.MethodsThis study presents the first shotgun metagenomics-based characterization of microbial communities in Kuwaiti waters of the northwest Arabian Gulf, focusing on Kuwait’s first Marine Protected Area (MPA) in Sulaibikhat Bay, a vital nursery ground for commercially important fish.ResultsAnalysis revealed significantly higher microbial diversity within the MPA compared to adjacent waters, with Rhodobacteraceae (27.8%) and Flavobacteriaceae (15.3%) being dominant. …”
Get full text

Development and Characterization of Anti-Nitr9 Antibodies by Radhika N. Shah, Ivan Rodriguez-Nunez, Donna D. Eason, Robert N. Haire, Julien Y. Bertrand, Valērie Wittamer, David Traver, Shila K. Nordone, Gary W. Litman, Jeffrey A. Yoder

“…The novel immune-type receptors (NITRs), which have been described in numerous bony fish species, are encoded by multigene families of inhibitory and activating receptors and are predicted to be functional orthologs to the mammalian natural killer cell receptors (NKRs). …”
Get full text

Renal Failure Associated with APECED and Terminal 4q Deletion: Evidence of Autoimmune Nephropathy by Mohammed Al-Owain, Namik Kaya, Hamad Al-Zaidan, Ibrahim Bin Hussain, Hadeel Al-Manea, Hindi Al-Hindi, Shelley Kennedy, M. Anwar Iqbal, Hamad Al-Mojalli, Albandary Al-Bakheet, Anne Puel, Jean-Laurent Casanova, Saleh Al-Muhsen

“…Chromosome analysis of the patient revealed 46,XY,del(4)(q33). FISH using a 4p/4q subtelomere DNA probe assay confirmed the deletion of qter subtelomere on chromosome 4. …”
Get full text

Integrated metabolomics and proteomics analysis to provide insights into muscle atrophy of turbot Scophthalmus maximus by dietary Clostridium autoethanogenum protein by Shihui Pan, Nan Bai, Zezheng Qi, Chuwen Chen, Daisong Ma, Zhenlin Liang, Min Gu

“…However, how CAP regulating these pathways was still unclear and there was no information on the comprehensive analysis for the mechanisms of CAP on fish muscle. In the present study, the integration of metabolomic and proteomic was applied on the muscle of turbot (initial weight of 150 ± 3 g) fed with fishmeal-based diet or diet with 60 % of fishmeal protein replaced by CAP for 70 days. …”
Get full text

Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization by Hang Xian, Huan Guo, Yuan-Ying Liu, Sui-Bin Ma, Rui Zhao, Jian-Lei Zhang, Hang Zhang, Rou-Gang Xie, Xu-Cheng Guo, Jie Ren, Sheng-Xi Wu, Ceng Luo, Rui Cong

“…Decreased expression of KCC2 in dorsal root ganglion (DRG) was detected through Western blot and FISH technology after BPA. Overexpression of KCC2 in DRG could reverse the hyperexcitability of DRG neurons and alleviate the pain of BPA mice synchronously. …”
Get full text

Appropriate dietary phosphorus levels promote growth performance, mineral retention, and hepatic lipid metabolism in juvenile American eels (Anguilla rostrata) by Yichuang Xu, Shuo Wang, Xinyu Hu, Pan Wang, Xiaozhao Han, Jinyue Yang, Ying Liang, Shaowei Zhai

“…Phosphorus (Pi) is an essential mineral for fish and exerts critical roles in growth, metabolism, and skeletal development. …”
Get full text

The effect of different feed on the spawning performance of mud crab Scylla serrata broodstock by Bethsy J. Pattiasina, Endang Jamal, Agapery Y. Pattinasarany

“…Treatments were consisted of: 1. PI (fresh meat fish of Decapterus sp. with dose of 5%), 2. PSC (fresh meat mixture of Decapterus sp. 1.8%, 3% of squid, and shrimp 1.2%), 3. …”
Get full text

Standardization of breeding and rearing of the endangered Indian catfish Clarias magur (Hamilton, 1822) for juvenile production by Kamal Sarma, Bavithra R., Jaspreet Singh, S.K. Ahirwal, Ujjwal Kumar, Tarkeshwar Kumar, Maneesh Kumar Dubey

“…The walking catfish, Clarias magur, is one of India's most popular food fish because of its nutritional quality and taste. …”
Get full text

Isotope analysis of birds’ eye lens provides early-life information by Emi A. Hasegawa, Jun Matsubayashi, Ichiro Tayasu, Tatsuhiko Goto, Haruka Inoue, Axel G. Rossberg, Chikage Yoshimizu, Masaru Hasegawa, Takumi Akasaka

“…This analysis has mostly been confined to fish for practical reasons and remains to be resolved for application to other animals. …”
Get full text

Association between dietary patterns and chronic kidney disease in elderly patients with type 2 diabetes: a community-based cross-sectional study by Ling Cao, Peng Yu, Lei Zhang, Qiuming Yao, Fang Zhou, Xiaoying Li, Xiaomu Li

“…A balanced dietary pattern, featured with high intake of fruits, dairy products, eggs, snacks, crab and shellfish, and fish and shrimp, was associated with lower CKD prevalence. …”
Get full text

Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals by Kate Britton, Orsolya Czére, Eléa Gutierrez, Linda M. Reynard, Eamon Laird, Gary Duncan, Baukje de Roos

“…For the remaining participants, no statistically-significant correlations were determined between mean hair 25(OH)D3 levels and self-reported data, including age, sex, BMI, vitamin D supplementation, frequency of oily fish consumption, and hours spent outside. For a subset of our cohort (n = 4) isotope analysis highlighted potential relationships between elevated δ 18O values (which can indicate season of hair growth) and 25(OH)D3 concentrations in some individuals, which may reflect seasonally-increased UVB exposure. …”
Get full text

Tannins for food preservation and human health: A review of current knowledge by Yesim Ozogul, Yilmaz Ucar, Eskindir Endalew Tadesse, Nikheel Rathod, Piotr Kulawik, Monica Trif, Tuba Esatbeyoglu, Fatih Ozogul

Get full text

Effect of Different Protein and Protein-Energy Ratio in Diet on Growth of Common Carp (Cyprinus carpio) Fingerling by M. Setiawati, R. Sutajaya, M. Agus Suprayudi

“…This can be achieved by using a diet containing suitable protein and protein-energy ratio for the need of fish cultured.  Diet containing different protein levels (28% and 31%) and protein-energy ratios (8 and 10), and a commercial feed as a control were compared to determine protein content and protein-energy ratio suitable for common carp fingerlings.  …”
Get full text

Quality improvement of rubber seed meal diet for Nile tilapia with amino acid supplemetation by Didi Humaedi Yusuf, Muhammad Agus Suprayudi, Dedi Jusadi

“…Tilapia with an initial body weight of 6.29±0.12 g were reared for 40 days and the fish were fed three times daily at satiation level (8.00 am, 12.00 pm and 16.00 pm). …”
Get full text

Neuroprotective Potential of <i>Origanum majorana</i> L. Essential Oil Against Scopolamine-Induced Memory Deficits and Oxidative Stress in a Zebrafish Model by Ion Brinza, Razvan Stefan Boiangiu, Iasmina Honceriu, Ahmed M. Abd-Alkhalek, Samir M. Osman, Omayma A. Eldahshan, Elena Todirascu-Ciornea, Gabriela Dumitru, Lucian Hritcu

“…In this research, we focused on the effects of <i>O. majorana</i> essential oil (OmEO, at concentrations of 25, 150, and 300 μL/L), evaluating chemical structure as well as its impact on cognitive performance and oxidative stress, in both naive zebrafish (<i>Danio rerio</i>), as well as in a scopolamine-induced amnesic model (SCOP, 100 μM). The fish behavior was analyzed in a novel tank-diving test (NTT), a Y-maze test, and a novel object recognition (NOR) test. …”
Get full text

Evaluation of X-Inactivation Status and Cytogenetic Stability of Human Dermal Fibroblasts after Long-Term Culture by Zhi-Gang Xue, Zhan-Ping Shi, Juan Dong, Ting-Ting Liao, Yan-Peng Wang, Xue-Ping Sun, Zheng-Jie Yan, Xiao-Qiao Qian, Yu-Gui Cui, Juan Chen, Jia-Yin Liu, Guoping Fan

“…Consistently, DNA fluorescent in situ hybridization (FISH) identified 3-4 copies of X chromosomes in one nucleus in this subset of cells with two inactive Xs. …”
Get full text