MLinvitroTox reloaded for high-throughput hazard-based prioritization of high-resolution mass spectrometry data by Katarzyna Arturi, Eliza J. Harris, Lilian Gasser, Beate I. Escher, Georg Braun, Robin Bosshard, Juliane Hollender

“…MLinvitroTox is a machine learning (ML) framework comprising 490 independent XGBoost classifiers trained on molecular fingerprints from chemical structures and target-specific endpoints from the ToxCast/Tox21 invitroDBv4.1 database. …”
Get full text

Genetically and chemically intraspecific variations of Ficus hirta provide novel insights into its protection and utilization by Jianling Chen, Qianqian Liu, Huihong Wang, Zhi Chao, Enwei Tian

“…In this study, we conducted an evaluation of the chloroplast DNA (cpDNA) genetic diversity and population structure of F. hirta in southern China, and further evaluated its medicinal quality based on HPLC fingerprinting and the content determination of the active components. …”
Get full text

Comparative analysis of feeding strategies and post mortem aging time on the oxidative status and color of the longissimus thoracis et lumborum muscle in Braford steers by María Sofía Castaño Ledesma, Gustavo Adolfo Palma, Gustavo Adolfo Palma, Claudio Darío Borsarelli, Claudio Darío Borsarelli, María Sumampa Coria, María Sumampa Coria

“…The content of heme pigment was determined by a spectrophotometric assay, while the fluorescence fingerprint of beef was evaluated by fluorescence spectroscopy excitation-emission matrices (FEEM). …”
Get full text

Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…In this study, we utilized a combinatorial functionomics approach, the Quadratic Phenotypic Optimization Platform (QPOP), to rationally design drug pairings that exploit the molecular fingerprint and vulnerability of established in vitro isogenic radioresistant (RR)-HNC models. …”
Get full text

Analysis of geothermal impact on metabolite compounds of heat-tolerant plant species using clustering and similarity cliff by N.B. Maulydia, K. Khairan, T.E. Tallei, F. Mohd Fauzi, R. Idroes

“…Clustering analysis and similarity cliff were assessed by employing the simplified molecular input line-entry system and fragment-based fingerprint.FINDINGS: Fifteen different plant species from diverse families—Apocynaceae, Asteraceae, Euphorbiaceae, Fabaceae, Lamiaceae, Moraceae, Pteridaceae, Rhamnaceae, and Verbenaceae were found in this study. …”
Get full text

Molecular characterization of ST15 carbapenem-resistant Klebsiella pneumoniae isolated in a single patient by Yongjin Hu, Rong Tang, Shanshan Jin, Jiahao Guan, Xiaoxiao Meng, Zengpeijie Dan, Ruilan Wang, Hong-Yu Ou, Jian Lu

“…The differences in DNA fingerprint bands among the nine KP isolates were ≤3, which can be classified as the same PFGE type. …”
Get full text

Identification of Southeast Asian Anopheles mosquito species with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a cross-correlation approach by Victor Chaumeau, Sunisa Sawasdichai, Thu Zar Ma Ma Moe Min, Thithiwarada Kularbkeeree, Naw Jaruwan, Naw Gloria, Naw Yu Lee, Muesuwa Trackoolchengkaew, Monticha Phanaphadungtham, Patcharamai Rongthong, Aritsara Inta, Wanitda Watthanaworawit, François Nosten

“…The absence of public repositories sharing mass spectra and open-source data analysis pipelines for fingerprint matching to mosquito species limits the widespread use of this technology. …”
Get full text

CLN6‐related continuum phenotype caused by aberrant splicing by Federica Invernizzi, Barbara Castellotti, Chiara Reale, Celeste Panteghini, Isabel Colangelo, Roberta Solazzi, Francesca Ragona, Lucio Giordano, Jessica Galli, Davide Rossi Sebastiano, Gianluca Marucci, Valeria Cuccarini, Giuseppe Didato, Cinzia Gellera, Barbara Garavaglia, Tiziana Granata, Laura Canafoglia

“…A skin biopsy revealed a mixed storage of curvilinear and fingerprint profiles. A brain MRI showed severe cortical atrophy. …”
Get full text

Cell culture expansion media choice affects secretory, protective and immuno-modulatory features of adipose mesenchymal stromal cell-derived secretomes for orthopaedic applications by Enrico Ragni, Andrea Papait, Michela Maria Taiana, Paola De Luca, Giulio Grieco, Elsa Vertua, Pietro Romele, Cecilia Colombo, Antonietta Rosa Silini, Ornella Parolini, Laura de Girolamo

“…Results: Within a conserved molecular signature, a divergent fingerprint emerged for ASCs' secretomes collected after expansion in standard FBS/hPL or next-generation S/X formulations. …”
Get full text

Targeting eEF1A reprograms translation and uncovers broad-spectrum antivirals against cap or m6A protein synthesis routes by Elisa Molina Molina, Joan Josep Bech-Serra, Eloi Franco-Trepat, Ignasi Jarne, Daniel Perez-Zsolt, Roger Badia, Eva Riveira-Muñoz, Edurne Garcia-Vidal, Lluís Revilla, Sandra Franco, Ferran Tarrés-Freixas, Núria Roca, Gerardo Ceada, Karl Kochanowski, Dàlia Raïch-Regué, Itziar Erkizia, Rytis Boreika, Antoni E. Bordoy, Laia Soler, Sonia Guil, Jorge Carrillo, Julià Blanco, Miguel Ángel Martínez, Roger Paredes, Alejandro Losada, Pablo Aviles, Carmen Cuevas, Júlia Vergara-Alert, Joaquim Segalés, Bonaventura Clotet, Ester Ballana, Carolina de la Torre, Nuria Izquierdo-Useros

“…By deciphering the molecular fingerprint of cells treated with therapies targeting translation we identify a rational approach to select broad-spectrum antivirals with potential to counteract future pandemic viruses.…”
Get full text

Spectrum-Effect Relationships of Flavonoids in Glycyrrhiza uralensis Fisch. by Tingting Li, Shiyao Hua, Jiahua Ma, Lin Dong, Fang Xu, Xueyan Fu

“…There were 15 common peaks in the fingerprints by similarity evaluations of the chromatographic fingerprints. …”
Get full text

Deciphering Design of Aggregation‐Induced Emission Materials by Data Interpretation by Junyi Gong, Ziwei Deng, Huilin Xie, Zijie Qiu, Zheng Zhao, Ben Zhong Tang

“…A new set of chemical fingerprints specifically tailored to the photophysics of AIE systems is developed. …”
Get full text

Molecular Cytogenetic Characterization of a Non-Robertsonian Dicentric Chromosome 14;19 Identified in a Girl with Short Stature and Amenorrhea by Usha R. Dutta, Vijaya Kumar Pidugu, Ashwin Dalal

Get full text

Classification of Complete Proteomes of Different Organisms and Protein Sets Based on Their Protein Distributions in Terms of Some Key Attributes of Proteins by Hao-Bo Guo, Yue Ma, Gerald A. Tuskan, Xiaohan Yang, Hong Guo

“…The two-dimensional maps (designated as fingerprints here) from the protein distribution densities in the LD space defined by ln(L) and ID are then constructed. …”
Get full text

New Bounds on 2-Frameproof Codes of Length 4 by Penying Rochanakul

“…Frameproof codes were first introduced by Boneh and Shaw in 1998 in the context of digital fingerprinting to protect copyrighted materials. These digital fingerprints are generally denoted as codewords in Qn, where Q is an alphabet of size q and n is a positive integer. …”
Get full text

Le site de la médiathèque Entre Dore et Allier à Lezoux (Puy-de-Dôme) : des traces papillaires antiques en contexte d’atelier de potiers by Aurore Lambert, André Desmarais, Cyril Driard

“…We studied the best preserved fingerprints on the site, on objects intended for ceramic kiln loading, and defined a recording and survey protocol. …”
Get full text

Rainy and Dry Seasons Are Relevant Factors Affecting Chemical and Antioxidant Properties of Meliponini Honey by Flavia C. Lavinas, Brendo A. Gomes, Marcos V. T. Silva, Raissa Lima, Suzana G. Leitão, Mirian R. L. Moura, Rosineide C. Simas, Renata F. Barbosa, Fabricio O. Silva, Carla S. Carneiro, Igor A. Rodrigues

“…The mineral content was assessed via TXRF spectroscopy, and chemical fingerprinting was conducted using mass spectrometry. …”
Get full text

Multidimensional Optimization of Signal Space Distance Parameters in WLAN Positioning by Milenko Brković, Mirjana Simić

“…Among the localization algorithms, nearest neighbor fingerprinting algorithms based on Received Signal Strength (RSS) parameter have been extensively studied as an inexpensive solution for delivering indoor Location Based Services (LBS). …”
Get full text

Screening hepatoprotective effective components of Lonicerae japonica Flos based on the spectrum-effect relationship and its mechanism exploring by Song Wang, Lin Yang, Ajiao Hou, Songtao Liu, Liu Yang, Haixue Kuang, Hai Jiang

“…Fingerprints of ten batches of LF were established by UPLC-PDA. …”
Get full text

Volatile Profile Characterization of Winter Jujube from Different Regions via HS-SPME-GC/MS and GC-IMS by Yening Qiao, Jinfeng Bi, Qinqin Chen, Xinye Wu, Min Gou, Haonan Hou, Xinwen Jin, Giorgia Purcaro

“…A combined untargeted and targeted approach was established for fingerprinting volatile organic compounds in winter jujubes from eight regions of China. …”
Get full text