Is hypercalcaemia immediately life-threatening? A prospective study by David Trewick, Mathilde Le Borgne, Julie Regnault, Camille Guimard

“…The primary outcome was the number of life-threatening cardiac arrhythmias (ventricular tachycardia, ventricular fibrillation, sinus arrest and second- or third-degree atrioventricular blocks) or neurological complications defined by a Glasgow Coma Scale score <9 during the stay in the ED. …”
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Differences in risk factor profiles for peripheral artery disease compared to coronary, cerebral and carotid artery by Stefan Acosta, Yufeng Du, Yan Borné, Anders Gottsäter

“…The diagnosis of incident PAD, coronary artery disease (CoAD), atherothrombotic ischemic stroke (IS) free from atrial fibrillation or flutter, and carotid artery disease (CaAD) was validated. …”
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Comparison of the safety and efficacy between minimally invasive cardiac surgery and median sternotomy in a low-risk mixed Asian population in Singapore by Zhi Xian Ong, Duoduo Wu, Haidong Luo, Guohao Chang, Faizus Sazzad, Jai Ajitchandra Sule, Peggy Hu, Theo Kofidis

“…On multivariate analysis, patients who underwent MICS had lower rates of atrial fibrillation (P = 0.021), reoperation (P = 0.028) and prolonged ventilation (P < 0.001). …”
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Gut microbiota and atrial cardiomyopathy by Tingting Sun, Beibei Song, Bo Li

“…Atrial cardiomyopathy is a multifaceted heart disease characterized by structural and functional abnormalities of the atria and is closely associated with atrial fibrillation and its complications. Its etiology involves a number of factors, including genetic, infectious, immunologic, and metabolic factors. …”
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Alteration of Thyroid-Related Hormones within Normal Ranges and Early Functional Outcomes in Patients with Acute Ischemic Stroke by Xiao-yan Xu, Wen-yu Li, Xing-yue Hu

“…On univariate analysis, poor functional outcome was associated with presence of atrial fibrillation as the index event. Furthermore, score of National Institutes of Health Stroke Scale (NIHSS), total T4, free T4, and C-reactive protein at admission were significantly higher in patients with poor functional outcome, whereas free T3 and total T3 were significantly lower. …”
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Diagnostic and prognostic significance of premature ventricular complexes in community and hospital-based participants: A scoping review. by Sukardi Suba, Kirsten E Fleischmann, Hildy Schell-Chaple, Priya Prasad, Gregory M Marcus, Xiao Hu, Michele M Pelter

“…Community-based longitudinal studies, which make up most of the literature, show that PVCs are associated with structural and coronary heart disease, lethal arrhythmias, atrial fibrillation, stroke, all-cause and cardiac mortality. …”
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HEMA-free versus HEMA-containing adhesive systems: a systematic review by Esraa Abdelkhalek, Hamdi H. Hamama, Salah H. Mahmoud

“…Although the addition of HEMA to dental adhesives improves dentin wettability and resin diffusion into demineralized collagen fibrils, HEMA’s high hydrophilicity can lead to hydrolytic degradation of the adhesive interface. …”
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Predictors of 7-day symptomatic hemorrhagic transformation in patients with acute ischemic stroke and proposal of a novel screening tool: A retrospective cohort study by Mehmet Muzaffer Islam, Cemrenur Uygun, Melike Delipoyraz, Merve Osoydan Satici, Servan Kurt, Enis Ademoglu, Serkan Emre Eroglu

“…Mechanical thrombectomy, atrial fibrillation, and diabetes mellitus were the independent predictors (P < 0.001, P = 0.003, P = 0.006, respectively). …”
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Risk Factors Associated with Cerebrovascular Diseases in Patients at the Tulcán Sur Health Center by María Verónica Aveiga Hidalgo, Dennis Mateo Lomas Males, Jordán Alexis Ruano Paspuel, Kevin Joel Salazar Estrada

“…The sociodemographic variables were analyzed: age and sex; clinical: presence or absence of high blood pressure, smoking, alcoholism, diabetes mellitus, dyslipidemia, atrial fibrillation and sedentary lifestyle. The normality of the data distribution was analyzed using the Kolmogorov-Smirnov test. …”
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Gut–brain axis and neuropsychiatric health: recent advances by Ceymi Doenyas, Gerard Clarke, Renáta Cserjési

“…The use of in vivo animal models has demonstrated that preformed α-synuclein fibrils (PFFs) can travel from the gut to the brain in a dosage-dependent manner, thereby supporting the “gut-first” theory in the context of PD, a theory that is explored in this Collection using in vitro approaches. …”
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Prediction of ischemic stroke in patients with H-type hypertension based on biomarker by Ke Chen, Jianxun He, Lan Fu, Xiaohua Song, Ning Cao, Hui Yuan

“…The final model included 8 predictors: age, antihypertensive therapy, biomarkers (serum magnesium, serum potassium, proteinuria and hypersensitive C-reactive protein), and comorbidities (atrial fibrillation and hyperlipidemia). The optimal model, named A2BC ischemic stroke model, showed good discrimination and calibration ability for ischemic stroke with AUC of 0.91 and 0.87 in the internal and external validation cohorts. …”
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The Formation of a Multifilament System Driven by Photospheric Converging Motions in a Bipolar Sunspot by Haitang Li, Jinhan Guo, Xin Cheng, Chang Zhou, Xiaoli Yan, Jun Chen, Yang Guo, Jacob Oloketuyi, Mingde Ding, Yu Liu

“…Before the filament appeared visible, the chromospheric fibrils gradually gathered together, evolving from a diffuse distribution into threadlike structures that were nearly parallel to the polarity inversion lines. …”
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Demineralized Freeze-Dried Bovine Cortical Bone: Its Potential for Guided Bone Regeneration Membrane by David B. Kamadjaja, Achmad Harijadi, Pratiwi Soesilawati, Eny Wahyuni, Nurul Maulidah, Akhsanal Fauzi, Fika Rah Ayu, Roberto Simanjuntak, R. Soesanto, Djodi Asmara, Andra Rizqiawan, Peter Agus, Coen Pramono

“…However, cross-linking of collagen fibrils was associated with poorer tissue integration and delayed vascular invasion. …”
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The study of the functionality of cardiomyocytes obtained from induced pluripotent stem cells for the modeling of cardiac arrhythmias based on long QT syndrome by M. M. Slotvitsky, V. A. Tsvelaya, S. R. Frolova, E. V. Dement’eva, K. I. Agladze

“…After an electrophysiological study on individual cardiac cells from patients with the LQT syndrome, it became apparent that the search for a mechanism for the transition of the normal heart rhythm to chaotic and fibrillation cannot be limited to recording ion currents in single cells. …”
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Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction by Elizabeth J. Wright, Nigel W. Hodson, Michael J. Sherratt, Moustapha Kassem, Andrew L. Lewis, Christine Wallrapp, Nadim Malik, Cathy M. Holt

“…After four weeks, infarcted areas were imaged using atomic force microscopy, demonstrating significant alterations between groups in the structure of collagen fibrils and resulting scar. Conclusions. These data demonstrate that MSCs ± GLP-1 exhibit modulatory effects on healing post-MI, affecting both apoptosis and collagen scar formation. …”
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A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide by Angelo Santoro, Antonio Ricci, Manuela Rodriquez, Michela Buonocore, Anna Maria D’Ursi

“…Investigating amyloid–β (Aβ) peptides in solution is essential during the initial stages of developing lead compounds that can influence Aβ fibrillation while the peptide is still in a soluble state. …”
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Rationale and design of a prospective, observational, multicentre study on the safety and efficacy of apixaban for the prevention of thromboembolism in adults with congenital heart... by Despoina Ntiloudi, Sotiria Apostolopoulou, Alexandra Frogoudaki, Haralambos Karvounis, George Giannakoulas, Anastasios Kartas, Ioannis Doundoulakis, Athanasios Koutsakis, Diamantis Kosmidis, Georgios Rampidis, Afrodite Tzifa, Dimosthenis Avramidis, Olga Ntzoyvara, Sotiria Liori, Tereza Mousiama, Sophia Anastasia Mouratoglou

“…Introduction The risk for stroke in adults with congenital heart disease (ACHD) is increased, especially in the setting of commonly ensuing atrial arrhythmias (AA), namely atrial fibrillation, atrial flutter or intra-atrial re-entrant tachycardia. …”
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J Point and ST Elevation Resembling Brugada: A Marker of Mortality in Methanol Toxicity by Mohammad Hossein Nikoo, Alireza Estedal, Kiana Khatami, Maryam Pakfetrat, Alireza Arjangzadeh, Shahrokh Sadeghi Boogar, Sina Danesh, Seyed Taghi Heydari

“…This clinical entity, among asymptomatic individuals with no family history of sudden cardiac death, would be reported in some severely ill patients before ventricular fibrillation. This study investigated the relationship between the electrocardiograms with demographic and laboratory data and also analyzed their association with mortality rate among patients with methanol poisoning. …”
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A Bioclinical Pattern for the Early Diagnosis of Cardioembolic Stroke by Bruno Zecca, Clara Mandelli, Alberto Maino, Chiara Casiraghi, Giovanbattista Bolla, Dario Consonni, Paola Santalucia, Giuseppe Torgano

“…At multiple logistic regression NT-proBNP>200 pg/mL, G/A ratio>0.70, and NIHSS score were independent predictors of cardioembolic stroke with high accuracy of the model, either including (AUC, 0.91) or excluding (AUC, 0.84) atrial fibrillation. Conclusions. A prediction model that includes NT-proBNP, G/A ratio, and NIHSS score can be useful for the early etiologic diagnosis of ischemic stroke.…”
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Left Atrial Appendage Occlusion in High Bleeding Risk Patients by Pierluigi Merella, Giovanni Lorenzoni, Alessandro P. Delitala, Filomena Sechi, Federica Decandia, Graziana Viola, Paola Berne, Gianluca Deiana, Patrizio Mazzone, Gavino Casu

“…The aim of this study was to investigate the outcomes of left atrial appendage occlusion (LAAO) in high bleeding risk patients suffering atrial fibrillation (AF) and to analyze the different antithrombotic therapies following the intervention. …”
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