Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer’s Disease by Cai Y, Huang G, Ren M, Chai Y, Fu Y, Yan T, Zhu L

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Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX-4 signaling pathway by Zitian Gao, Gaorui Wang, Yujie Chen, Wuke Yuan, Jun Cai, Aiping Feng, Jie Fang, Qi Xu, Xiaojun Wu

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MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production by Xinrui Yang, Jing Liu, Yaru Yin, Luxun Yang, Mingquan Gao, Zifei Wu, Binghui Lu, Shenglin Luo, Weidong Wang, Rong Li

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Microglial Nrf2-mediated lipid and iron metabolism reprogramming promotes remyelination during white matter ischemia by Hang Zhang, Sheng Yang, Yi-Lin Lu, Luo-Qi Zhou, Ming-Hao Dong, Yun-Hui Chu, Xiao-Wei Pang, Lian Chen, Lu-Lu Xu, Lu-Yang Zhang, Li-Fang Zhu, Ting Xu, Wei Wang, Ke Shang, Dai-Shi Tian, Chuan Qin

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Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1 by Baocheng Xie, Peishan Wu, Hongyu Liu, XiangDi Yang, Linxuan Huang

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Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu... by Qiao Tang, Jiatao Xie, Yifei Wang, Chong Dong, Chong Dong, Qian Sun

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Molecular insights into the interplay between type 2 diabetes mellitus and osteoporosis: implications for endocrine health by Liyun Jiang, Xia Song, Li Yan, Yali Liu, Xiumei Qiao, Wen Zhang

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Exploring Amanita muscaria (L.) Lam.: Cytotoxic, proapoptotic and antiferroptotic effect of acetone extract on JAR choriocarcinoma cell line by Milojević Sara D., Nikodijević Danijela D., Milutinović Milena G., Kosanić Marijana M., Petrović Nevena N., Jovanović-Krivokuća Milica G., Nacka-Aleksić Mirjana M.

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Investigating the Pulmonary Host Response of <i>Acinetobacter baumannii</i> Infection-Associated Pneumonia by Metagenomic Next-Generation Sequencing by Mu-Jung Chou, Chih-Hung Cheng, Hui-Ching Wang, Ming-Ju Tsai, Chau-Chyun Sheu, Wei-An Chang

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Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis by Qinzhen Lu, He Ling, Yonghui Lao, Junjie Liu, Wei Su, Zhao Huang

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Inhibiting de novo lipogenesis identifies a therapeutic vulnerability in therapy-resistant colorectal cancer by Eeshrita Jog, Ashwin Kumar Jainarayanan, Alessandro La Ferlita, Arnab Chakraborty, Afiya Dalwai, Showket Yahya, Anusha Shivashankar, Bhagya Shree Choudhary, Aakash Chandramouli, Mufaddal Kazi, Darshan Jain, Nileema Khapare, Akshaya B, Bushra K. Khan, Poonam Gera, Prachi Patil, Rahul Thorat, Nandini Verma, Lalit Sehgal, Avanish Saklani, Siddhesh S. Kamat, Sorab N. Dalal, Nazia Chaudhary

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Resistance to death pathway induction as a potential targeted therapy in CRISPR/Cas-9 knock-out colorectal cancer cell lines by Malgorzata Adamiec-Organisciok, Magdalena Wegrzyn, Lukasz Cienciala, Ngoni Magate, Magdalena Skonieczna, Joanna Nackiewicz

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Iron depletion in “metabolic fatty liver syndromes”: a strong biological rationale with disappointing liver outcomes by Amedeo Lonardo

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Bone marrow mesenchymal stem cell-originated exosomes suppress activation of hepatic stellate cells through the miR-144-3p/SLC7A11 axis by Yanqin Hao, Rong Wang, Qing Zhou, Jiaolong Ren

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GPX modulation promotes regenerative axonal fusion and functional recovery after injury through PSR-1 condensation by Su-Hyuk Ko, Kyung-Ah Cho, Xin Li, Qitao Ran, Zhijie Liu, Lizhen Chen

“…Ferroptosis-induced lipid peroxidation enhances injury-triggered phosphatidylserine exposure (PS) to promote axonal fusion through PS receptor (PSR-1) and EFF-1 fusogen. …”
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REVIEW by Claudia-Ştefania Bala

“…Iron, ferroptosis and association with tumoral evolution and potential therapeutic impact Decision making in Merkel cell carcinoma – surgical oncologist point of view Cardiac toxicity of checkpoint inhibitors (CPI) used in cancer immunotherapy Immune-mediated complications of monoclonal antibodies used in onco-hematology …”
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Exploring Liraglutide’s mechanism in reducing renal fibrosis: the Fsp1-CoQ10-NAD(P)H pathway by Qi Chen, Ji-Xian Song, Zhi Zhang, Ji-Ren An, Yu-Jing Gou, Miao Tan, Yashuo Zhao

“…Furthermore, LIRA inhibited ferroptosis by adjusting the Fsp1-CoQ10-NAD(P)H pathway in vivo and in vitro. …”
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Multiomics identify the gene expression signature of the spinal cord during aging process by Lintao Xu, Jingyu Wang, Jinjie Zhong, Weiwei Lin, Gerong Shen, Ning He, Xingjia Mao, Chunyan Fu, Zhaobo Huang, Fengdong Zhao, Xin Ye, Yongjian Zhu, Mingzhi Zheng, Hui Li, Lin-lin Wang, Kai Zhong, Lijun Zhu, Ying-ying Chen

“…Flow cytometry reveals increased accumulation of free Fe2+ and ROS in senescent mixed glial cells; however, CCK-8 assays reveal that these cells are resistant to ferroptosis. SiRNA and lentivirus experiments indicate that the overexpression of Fth1 in normal mixed glial cells reduces their sensitivity to ferroptosis, whereas Fth1 knockdown increases their sensitivity to ferroptosis. …”
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Exploring molecular disparities of H-type vasculature endothelial cells in osteonecrosis of the femoral head through single-cell analysis by Wei Shi, Dong Li, Qian Xu, Kai Zhang, Xinyu Liang, Hui Li, Zhijun Li, Huafeng Zhang

“…The hypoxia index was higher, with ferroptosis increased in stage 3 A and parthanatos in stages 3 A and 4. …”
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Roles and Mechanisms of Regulated Necrosis in Corneal Diseases: Progress and Perspectives by Wanying Lin, Minting Chen, Yacouba Cissé, Xiaofeng Chen, Lang Bai

“…Various forms of regulated necrosis, particularly pyroptosis, necroptosis, and ferroptosis, have been implicated in the pathogenesis of corneal disease. …”
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