Impact of cariprazine on body weight and blood pressure among adults with bipolar I disorder, schizophrenia, or major depressive disorder in a real-world setting by Christoph U. Correll, Andrew J. Cutler, François Laliberté, Guillaume Germain, Sean D. MacKnight, Julien Boudreau, Sally W. Wade, Nadia Nabulsi, Huy-Binh Nguyen, Mousam Parikh

“…The mean patient age was 43.4 years, 75.2% were female, and the mean (SD) on-treatment period was 219 (185) days. …”
Get full text

Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally... by Li Zhang, Jiong Wu, Guangyu Liu, Shuang Hao, Jianjing Hou, Changming Zhou, Yifeng Hou, Keda Yu, Zhen Hu, Genhong Di, Zhi Min Shao, Xiaoli Yu

“…Further evaluation in a randomised trial comparing preoperative radiotherapy versus conventional PMRT in breast reconstruction is required to assess both oncological and patient-reported outcomes (PROs).Methods and analysis The CAPPELLA trial is a prospective, multicentre, open-label, randomised controlled trial across nine centres comparing PROs and safety outcomes between preoperative and postoperative radiotherapy in patients with locally advanced breast cancer requiring immediate DIEP flap reconstruction. Female patients aged >18 years with breast cancer who are treated with neoadjuvant systemic treatment, require both mastectomy and radiotherapy and are suitable for DIEP flap reconstruction will be included. …”
Get full text

Examining teen club attendance and viral load suppression among adolescents under differentiated HIV care in Malawi: a sub-optimal scenario by Rachel Chamanga, Tessa Musukwa, Louiser Kalitera, Felix Gent, Harrid Nkhoma, Kwashie Kudiabor, Alice Maida, Dumbani Kayira, Verita Buie, Godfrey Woelk, Thulani Maphosa

“…Results Our analysis included 1,162 ALHIV with a median age of 15 years (IQR 13–17). The majority were female (n = 614, 53%) and attended one or two teen club visits (n = 665, 57%). …”
Get full text

Genetic Predisposition and Salt Sensitivity in a Chinese Han Population: The EpiSS Study by Kuo Liu, Bo Xi, Zheng Liu, Han Qi, Bin Liu, Jie Zhang, Han Cao, Yuxiang Yan, Min Zhao, Yan He, Ling Zhang

“…The mean age of the participants was 57.1 years, and most of them were female (77.4%). The prevalence of SS was 28.7%. Both the continuous PRS and PRS tertiles were significantly associated with the risk of SS and a BP increase of more than 5 mmHg during acute salt loading but were not associated with a BP decrease of more than 10 mmHg during the diuresis shrinkage process. …”
Get full text

Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study by Miyuki Tsuruoka, Mai Kim Huynh, Michiko Toizumi, Thanh Tien Hoang, Trieu Bao Nguyen, Anh The Dao, Luong Dinh Nguyen, Huy Xuan Le, Chung Thanh Le, Anh Quang Dang, Hung Thai Do, Lay Myint Yoshida

“…The proportions of participants who had at least one long COVID symptom within the 7 days of each follow-up at 6 and 16 months were 72.0% (134/186) and 63.5% (47/74), respectively. We also found that females and adults reported symptoms more often in the follow-up surveys, 78.9% (90/114) [females] vs 61.1% (44/72) [males] at 6 months, P = 0.008; 68.7% (46/67) [ $$\ge$$ ≥ 20 years] vs 14.3% (1/7) $$[<$$ [ < 20 years] at 16 months, P = 0.004. …”
Get full text

Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review by Annika Smith, Aidin Karahasan, Deborah Yi, Sanjay Yapabandara, James Elhindi, Pablo Fernandez-Penas, Clara Chow, Sarah Zaman

“…Of the 39 participants, 31 (79.5%) were male, 8 (20.5%) were female; 26 (67%) were biologic experienced (BE) and 13 (33%) were biologic naïve (BN). …”
Get full text

Examining the association between public health unit spending and adolescent substance use by Urvi Rai, Karen A. Patte, Brendan T. Smith, Ambikaipakan Senthilselvan, Elaine Hyshka, Scott T. Leatherdale, Roman Pabayo

“…Results: Approximately 50 % of the study sample was female and the majority identified as being White. …”
Get full text

Unmet Supportive Care Needs of Lung Cancer Survival Patients at Different Cancer Stages and Treatment Phases by Lee PY, Chen YA, Tsai TH, Chen CY, Shieh SH

“…Associations with sex, age, cancer stage, and treatment phase were investigated.Results: Compared with male patients, female patients exhibited fewer unmet health information needs (aOR=0.40; p=0.021). …”
Get full text

Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse by Qiaoling Wang, Fengli Chi, Yingdong Liu, Qiurong Chang, Siyu Chen, Pengcheng Kong, Wanli Yang, Wenqiang Liu, Xiaoming Teng, Yan Zhao, Yi Guo

“…Differential metabolites in follicular fluid were analyzed via untargeted metabolomics. Female mice were exposed to polyethylene (PE) to validate human findings. …”
Get full text

The Effect of Prejudice and Discrimination Education Given to University Students on Gender Perception and Attitude by Neslihan Nur Pehlivan

“…According to the students' descriptive characteristics, it was found that the mean age of the participants in the study was 21.6±3.3, and that 73.7% of them were female. According to the study, most students' mothers (56.9%) and fathers (38.9%) had completed elementary school. …”
Get full text

Hubungan Kejadian Internet Addiction dengan Prestasi Belajar pada Mahasiswa FK Unand by Rizky Erizka, Nadjmir Nadjmir, Elly Usman

“…Based on the analyzed result, it confirm that the internet addiction cause problems in academic</em><em> achievement</em><em>. 1.1% samples suffer the severe internet addiction, intermediate 34.4% and mild 37.7%. By gender, more females suffer the internet addiction than males</em><em> because there </em><em>were</em><em> more female than male</em><em>. …”
Get full text

Digital Twin Technology in Resolving Polycystic Ovary Syndrome and Improving Metabolic Health: A Comprehensive Case Study by Paramesh Shamanna, MD, Anuj Maheshwari, MD, Ashok Keshavamurthy, MD, Sanjay Bhat, DM, Abhijit Kulkarni, DM, Shivakumar R, MD, Kumar K, MD, Mukulesh Gupta, MD, Mohamed Thajudeen, MD, Ranjita Kulkarni, MD, Shashikiran Patil, MD, Shashank Joshi, DM

“…Case Report: A 38-year-old female with typical PCOS features presented with hypertension, obesity, and elevated fasting and postprandial insulin levels. …”
Get full text

Autoantibodies in type 1 diabetes: Prevalence and clinical profiles by Raja Hazime, Saad Lamjadli, Morad Guennouni, Mounir Belkrachni, Fatima-Ezzohra Eddehbi, Ider Oujamaa, Lahcen Elmoumou, Aicha Bourrahouate, Imane Ait Sab, Hicham Baizri, Nawal El Ansari, Brahim Admou

“…A multicenter cross-sectional study was carried out on 276 patient-first with T1D, including 167 pediatric (60.5 %) and 109 adult (39.5 %) cases, of which 144 were female and 132 were male (sex ratio= 0.91),with an average age of 14.1 ± 8.0 years. …”
Get full text

Role of Vitamin D Status and Alterations in Gut Microbiota Metabolism in Fibromyalgia-Associated Chronic Inflammatory Pain by Caterina Saija, Maria Paola Bertuccio, Alberto Scoglio, Vincenzo Macaione, Francesco Cacciola, Giuseppe Micalizzi, Daniela Caccamo, Carolina Muscoli, Monica Currò

“…<b>Methods</b>: Blood samples were collected from sixty-eight female FM patients (49.9 ± 12.35 years). Pain intensity was assessed by FIQ-R. …”
Get full text

Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring by Fengxu Wang, Jin Wang, Na Luo, Yonghua Luo, Zhengnan Gao, Ye Cui, Mengna Jiang, Zhaoping Shen, Jing Xiao, Peng Xue, Xiaoke Wang, Shali Yu, Qiyun Wu, Xinyuan Zhao

“…In contrast with the control group, prenatal PS-NPs exposure obviously decreased brain tissue weight and the organ coefficient (brain weight/body weight) in adult male mice, but it only led to changes in the low-dose group of female mice. Histological examination of the adult offspring brains revealed alterations following exposure to PS-NPs during gestation. …”
Get full text

Home high-flow therapy during recovery from severe chronic obstructive pulmonary disease (COPD) exacerbation: a mixed-methods feasibility randomised control trial by Nicholas Hart, Louise Rose, Abdel Douiri, Georgios Kaltsakas, Eui-Sik Suh, Patrick B Murphy, Anne Rossel, Rebecca F D'Cruz

“…Trial progression criteria were: ≥40% of eligible patients randomised, ≤20% attrition, ≥70% complete data, and no device-related serious adverse events (SAE).Results 18 of 45 eligible patients were randomised (age 69±5 years, 44% female, body mass index 23±5 kg/m2, forced expiratory volume in 1 second 32±12%). …”
Get full text

Real-World Experience with CDK4/6 Inhibitors in the First-Line Palliative Setting for HR+/HER2− Advanced Breast Cancer by Ram Patel, John Mathews, Caroline Hamm, Swati Kulkarni, Rasna Gupta, Tarquin Opperman, John Dean Chiong, Abdullah Nasser

“…The cohort was predominantly female (98.7%) and postmenopausal (77.3%), with 52.0% having de novo stage IV disease. …”
Get full text

Rumen-Degradable Starch Improves Rumen Fermentation, Function, and Growth Performance by Altering Bacteria and Its Metabolome in Sheep Fed Alfalfa Hay or Silage by Wenliang Guo, Meila Na, Shuwei Liu, Kenan Li, Haidong Du, Jing Zhang, Renhua Na

“…Nevertheless, increasing dietary energy can enhance ruminal microbial protein synthesis. Thirty-two Suffolk female sheep were used in this study, with a 2 × 2 factorial arrangement of treatment. …”
Get full text

Federally qualified health center patients’ experiences with remote patient monitoring as part of telehealth services for self-measured blood pressure monitoring by Natalia I. Heredia, Maria E. Fernandez, Ella R. Garza, Jabria Pittman, Fernanda Velasco-Huerta, Tracy L. Judd, Jocelyn Hunyadi, Elvis Longanga Diese, Deevakar Rogith, William B. Perkison, Susan H. Fenton

“…Results The sample (n = 47) was 64% female, 89% Hispanic/Latino, and 75% uninsured. Participants used RPM for SMBP an average of 46 days and 72 times within the first 120 days (~ 4 months). …”
Get full text

Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population by M. A. Charles-Davies, A. A. Fasanmade, J. A. Olaniyi, O. E. Oyewole, M. O. Owolabi, J. R. Adebusuyi, O. Hassan, M. T. Ajobo, M. O. Ebesunun, K. Adigun, K. S. Akinlade, U. A. Fabian, O. O. Popoola, S. K. Rahamon, W. Okunbolade, M. A. Ogunlakin, O. G. Arinola, E. O Agbedana

“…HTN was associated with MS and female gender (P<0.05). Metabolic alterations and significant HTN were observed. …”
Get full text