Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal by Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani

“…We identified five cases of KDT failure in female GLUT1DS patients, aged 10 days to 13 years at diagnosis. …”
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Sexual Dimorphism for the Association between Vitamin D and Insulin Resistance in Chinese People by Bing Han, Qin Li, Ningjian Wang, Yi Chen, Chunfang Zhu, Yingchao Chen, Fangzhen Xia, Zhen Cang, Meng Lu, Ying Meng, Chi Chen, Yingli Lu

“…Increasing 25(OH)D levels were associated with reduced trend of homeostasis model assessment of insulin resistance (HOMA-IR) in both males and females. Pearson’s correlation indicated 25(OH)D level was inversely associated with the HOMA-IR for male subjects (r=−0.055, P=0.028) but not for female subjects (r=−0.005, P=0.798). …”
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The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis by Jingmin Song, Heqing Wang, Xiaolian Gao, Fen Yang, Xinhong Zhu, Guiyuan Qiao, Ting Gan, Junxiu Tao

“…Meta-regression analysis identified the hepcidin measurement method (p < 0.01), male-to-female ratio (p < 0.01), and study quality (p < 0.01) as significant moderators of the observed heterogeneity. …”
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Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile. by Javiera Leniz, Sam Hernández-Jaña, Mauricio Soto, Eduardo Arenas, Paula Margozzini, Francisco Suarez, Daniel Capurro, María Paulina Rojas, Claudia Bambs

“…The mean age was 44.30 (sd 17.31), 55.6% were female, 15.9% had a type of healthcare insurance for people from the lowest category of income, 11.6% and 9.4% had a record of hypertension or diabetes mellitus diagnosis. …”
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Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas by James D. Phillips, Tyler Merrill, J. Reed Gardner, R. Thomas Collins, Jenika Sanchez, Adam B. Johnson, Brian K. Eble, Larry D. Hartzell, Jay M. Kincannon, Gresham T. Richter

“…A total of 333 patients (75% female) received propranolol therapy. ECG information was available for 317 (95%). …”
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Intelligent measurement of adolescent idiopathic scoliosis x-ray coronal imaging parameters based on VB-Net neural network: a retrospective analysis of 2092 cases by Jinlong Liu, Haoran Zhang, Pei Dong, Danyang Su, Zhen Bai, Yuanbo Ma, Qiuju Miao, Shenyu Yang, Shuaikun Wang, Xiaopeng Yang

“…Results The differences in CA, CBD, CV, RSH, TI tilt, PT, LLD and SS were statistically significant between male and female genders (p < 0.05); Differences in CA, CBD, T1 Tilt, PT, SS, AVT and TS were statistically significant in patients with AIS of different severity (p < 0.001), and T1 Tilt, AVT, TS were risk factors; Differences in CA, CBD, CV, RSH, T1 Tilt, PT, LLD, SS, AVT and TS were statistically significant (p < 0.05) in patients with AIS of different curve types, and TS was a risk factor; Analyzing the correlation between parameters revealed a highly linear correlation between CV and RSH (r = 0.826, p < 0.001), and a significant linear correlation between CBD and TS, and PT and SS (r = 0.561, p < 0.001; r = 0.637, p < 0.001). …”
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Predictors of Cardiovascular Autonomic Neuropathy Onset and Progression in a Cohort of Type 1 Diabetic Patients by M. Matta, A. Pavy-Le Traon, S. Perez-Lloret, C. Laporte, I. Berdugo, N. Nasr, H. Hanaire, J. M. Senard

“…Methods. 175 type 1 diabetic patients (mean age: 50 ± 11 years; female/male: 76/99) with positive bedside screening for CAN were included and underwent 2 standardized autonomic testings using 4 standardized tests (deep breathing, Valsalva maneuver, 30/15 ratio, and changes in blood pressure during standing), separated by 3 ± 1 years. …”
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An Unusually Short Latent Period of Therapy-Related Myeloid Neoplasm Harboring a Rare MLL-EP300 Rearrangement: Case Report and Literature Review by Reina Takeda, Kazuaki Yokoyama, Seiichiro Kobayashi, Toyotaka Kawamata, Sousuke Nakamura, Tomofusa Fukuyama, Mika Ito, Nozomi Yusa, Eigo Shimizu, Nobuhiro Ohno, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Kaoru Uchimaru, Arinobu Tojo

“…Here, we report a 62-year-old female who developed t-MN only three months after the completion of conventional chemotherapy and anti-CCR4 antibody for ATL acute type. …”
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PENINGKATAN KEMAMPUAN GENERIK FISIKA DAN PEMAHAMAN KONSEP DALAM PEMBELAJARAN GUIDED DISCOVERY MELALUI EKSPERIMEN PADA ALAT-ALAT OPTIK by Partogi Nainggolan, Nyoman Rohadi, Eko Risdianto

“…Subjects in this study were all students of class XI MIA 2 that consists of 32 people consisting of 14 male students and 18 female students. Generic physics ability of learners in the first cycle obtained the matter absorption of 73.13% and mastery learning of 53.13% (not completed), cycle II obtained for matter absorption of 74.22% and mastery learning by 75% (not completed) , and cycle III with the matter absorption of 80% and 100% (completed). …”
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Balanced crystalloid versus saline for resuscitation in pediatric septic shock: a systematic review and meta-analysis by Barkhá Vijendra, Ana Beatriz Bertol, Mylena Maria Guedes de Almeida, Pedro Henrique Aquino Gil de Freitas, Áurea Maria Salomão Simão, Bianca Lisa de Faria

“…The mean age was 5.98 ± 3.08 years, with 43.82% female patients. Follow-up ranged from 3 to 90 days. …”
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Disability and Migration Routes: An Explorative Analysis Among Refugees Hosted in Italy by Marco Tofani, Marco Tofani, Maurizio Marceca, Maurizio Marceca, Donatella Valente, Donatella Valente, Giovanni Galeoto, Giovanni Galeoto, Mohamed Ali Ben Zina, Imène Soumaya Salhi, Khadija Elmadmad, Khadija Elmadmad, Hind Tak Tak, Justine Gosling, Satish Mishra, Valentina Gazzaniga, Marco Cilione, Silvia Iorio

“…Data on migration routes were collected and the relationship with functioning limitations was explored.Results483 refugees (58.18% males - 41.82% female) were interviewed. 23.8% were found to have a disability, with a higher risk for those who travelled along the central Mediterranean route OR (95% CI) 2.08 (1.33–3.24). …”
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A deep learning approach for automatic 3D segmentation of hip cartilage and labrum from direct hip MR arthrography by Malin Kristin Meier, Ramon Andreas Helfenstein, Adam Boschung, Andreas Nanavati, Adrian Ruckli, Till D. Lerch, Nicolas Gerber, Bernd Jung, Onur Afacan, Moritz Tannast, Klaus A. Siebenrock, Simon D Steppacher, Florian Schmaranzer

“…Inter-rater agreement of manual segmentation served as benchmark for automatic segmentation performance. 100 patients were included (mean age 30 ± 10 years, 64% female patients). Mean DSC for cartilage was 0.92 ± 0.02 (95% confidence interval [CI] 0.92–0.93) and 0.83 ± 0.04 (0.81–0.85) for labrum and comparable (p = 0.232 and 0.297, respectively) to inter-rater agreement of manual segmentation: DSC cartilage 0.93 ± 0.04 (0.92–0.95); DSC labrum 0.82 ± 0.05 (0.80–0.85). …”
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Impact of Edible Insect Polysaccharides on Mouse Gut Microbiota: A Study on White-Spotted Flower Chafer Larva (<i>Protaetia brevitarsis seulensis</i>) and Silkworm Pupa (<i>Bombyx... by Joon-Ha Lee, Hyojung Son, Sathiyamoorthy Subramaniyam, Hyun-Jung Lim, Sohyun Park, Ra-Yeong Choi, In-Woo Kim, Minchul Seo, Hae-Yong Kweon, Yongsoon Kim, Seong-Wan Kim, Jong-Soon Choi, Younhee Shin

“…We investigated the effects of two commonly consumed insects, <i>Protaetia brevitarsis seulensis</i> larva and <i>Bombyx mori</i> pupa, on beneficial gut microbiota growth, using whole 16s metagenome sequencing to assess diet-associated changes. Seven-week-old female C57BL/6J mice were administered the edible insects, along with fracto-oligosaccharide (FOS) as a positive control and sham (phosphate buffer saline (PBS)) as a negative control, to assess the relative abundance of insect-diet-associated gut microbes. …”
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Expanded screening for Fabry disease in patients with chronic kidney disease not on dialysis: a multicenter Italian experience by Yuri Battaglia, Federica Baciga, Meilad Shakkour, Savio Russo, Giulia Carnicella, Michela Erlati, Gemma Sartori, Giulia Tronconi, Renzo Mignani, Federico Pieruzzi, Paolo Colomba, Laura Scichilone, Michele Andreucci, Concetto Sessa, Giovanni Duro

“…Genetic testing was also performed in all females and males with low α-Gal A activity. Inclusion criteria were: (1) females ≥18 years old; (2) males aged between 18 and 70 years; (3) NDD-CKD stages 1–5. …”
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Questionnaire to Survey Cosmetic Outcomes in Laparoscopic Surgery for Colorectal Cancer by Masaaki Miyo, MD, PhD, Ichiro Takemasa, MD, PhD, Koichi Okuya, MD, PhD, Tatsuya Ito, MD, PhD, Emi Akizuki, MD, PhD, Tadashi Ogawa, MD, PhD, Ai Noda, MD, Masayuki Ishii, MD, PhD, Ryo Miura, MD, Momoko Ichihara, MD, Maho Toyota, MD, Akina Kimura, MD, Mitsugu Sekimoto, MD, PhD

“…Participants who were female, younger, and in the nonmedical group placed great importance on cosmetic outcomes. …”
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Ductal Carcinoma In Situ (DCIS) Diagnosed by MRI-Guided Biopsy among BRCA1/BRCA2 Mutation Carriers by Renata Faermann, Eitan Friedman, Orit Kaidar-Person, Jonathan Weidenfeld, Malka Brodsky, Anat Shalmon, Osnat Halshtok Neiman, Michael Gotlieb, Yael Yagil, David Samoocha, Dana Madorsky Feldman, Miri Sklair-Levy

“…Materials and Methods. All female BRCA1/BRCA2 PSV-carriers followed at the Meirav High-risk clinic from 2015 to 2020 were eligible if they underwent semiannual breast imaging (MRI/mammography) and MRI-guided biopsy-proven pure DCIS. …”
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Safety and Feasibility of Transanal Endoscopic Surgery for Diffuse Cavernous Hemangioma of the Rectum by Ziwei Zeng, Xianrui Wu, Junji Chen, Shuangling Luo, Yujie Hou, Liang Kang

“…Four patients (57.1%) were male, with a mean age at surgery of 34.5±7.7 years, and three patients (42.9%) were female, with a mean age at surgery of 29.9±3.8 years. …”
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The value of blood lactate and lactate clearance rate in evaluating the prognosis of athletes with heat illness of varying degrees after high-intensity exercise by Li Yu, Xuehui Dong, Huanhuan Li, Lili Mi

“…The study population consisted of two groups of high level athletes: the favourable Prognosis Group (< 7 days, 22 cases), comprising 21 males and 1 female with a mean age of 21.8 ± 2.7 years, and the bad Prognosis Group (≥ 7 days, 14cases), consisting of 14 males with a mean age of 22.6 ± 3.2 years. …”
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Impact of Timing the Combination of Radiotherapy and PD-1 Inhibitors on Outcomes in Patients with Hepatocellular Carcinoma by Zhong L, Peng W, Sun J, Luo Y, Sheng H, Wu Y, Zhou T, Zhou C, Cao C

“…Additionally, we created an experimental tumor model using 6-week-old female mice to validate our findings.Results: In the concurrent group, the median overall survival was indefinite; however, it was 13 months in the sequential group (95% confidence interval [CI] 6.7– 19.3 months, P=0.010). …”
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Associations between hypovitaminosis D, adiposity indices and insulin resistance in adolescents: mediation analyses from NHANES 2011–2018 by Yaping Deng, Yingting Luo, Yilei Shen, Yong Zhao, Wei Cao, Jie Cao, Lijuan Xu, Lin Kong

“…Notably, subgroup analysis indicated a pronounced hypovitaminosis D -adiposity association in female adolescents, which was not observed in males. …”
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