Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome by Jan Soukop, Ludmila Kazdová, Martina Hüttl, Hana Malínská, Irena Marková, Olena Oliyarnyk, Denisa Miklánková, Soňa Gurská, Zuzana Rácová, Martin Poruba, Rostislav Večeřa

“…<b>Results:</b> Fenofibrate treatment (100 mg/kg BW/day for four weeks) significantly decreased serum levels of triglyceride, (−77%) and free fatty acids (−29%), the hepatic accumulation of triglycerides, and the expression of genes encoding transcription factors involved in lipid metabolism (Srebf2, Nr1h4. …”
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Gut Dysbiosis and Abnormal Bile Acid Metabolism in Colitis-Associated Cancer by Li Liu, Min Yang, Wenxiao Dong, Tianyu Liu, Xueli Song, Yu Gu, Sinan Wang, Yi Liu, Zaripa Abla, Xiaoming Qiao, Wentian Liu, Kui Jiang, Bangmao Wang, Jie Zhang, Hailong Cao

“…The abundance of pathogens was increased, while the short-chain fatty acids producing bacteria were reduced. Interestingly, Clostridium XlV and Lactobacillus, which might be involved in the bile acid deconjugation, transformation, and desulfation, were significantly decreased. …”
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Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6 by Byung Kil Park, Eun-Ah Lee, Hee-Youn Kim, Jun Choul Lee, Koon Soon Kim, Won Hoon Jeong, Ki Young Kim, Bon Jeong Ku, Sang Dal Rhee

“…The fasting plasma concentrations of glucose, triglyceride, cholesterols, free fatty acids, and HOMA-IR were measured and the glucose tolerance and insulin resistance tests were performed in the 25-week-old Mig-6f/f and the Mig-6d/d mice. …”
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New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis by Sameh A. Abdelnour, Walaa M. Essawi, Nasser Ghanem, Ibrahim T. El-Ratel, Abdel-Wahab A. Abdel-Warith, Elsayed M. Younis, Ahmed N. F. Neamat-Allah, Shimaa A. Amer, Simon J. Davies, Ali Ali El-Raghi

“…Meanwhile, beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), and somatic cell counts in milk (SCC) were significantly reduced by ASG supplementation. …”
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<i>Syntrichia laevipila</i> Brid., a Bryophyta from Northwest Argentina as a Source of Antioxidants and Antimicrobials by Luis Ignacio Jiménez, Florencia Maria Correa Uriburu, José Javier Martínez Chamás, Guillermo Martin Suárez, Iris Catiana Zampini, Mario J. Simirgiotis, María Inés Isla

“…UHPLC/ESI/MS/MS analysis identified 32 peaks, including phenolic compounds (phenolic acids, lignans, chalcones, and flavonoids) and non-hydrophilic compounds (terpenoids, fatty acids, and brassinosteroids). Maslinic and oleanolic acids, two triterpenoids present in S. …”
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Butyrate Enhances Desensitization Induced by Oral Immunotherapy in Cow’s Milk Allergic Mice by Marlotte M. Vonk, Bart R. J. Blokhuis, Mara A. P. Diks, Laura Wagenaar, Joost J. Smit, Raymond H. H. Pieters, Johan Garssen, Léon M. J. Knippels, Betty C. A. M. van Esch

“…Fermentation of FOS by intestinal bacteria leads to production of short-chain fatty acids (SCFA) including butyrate. Aim. To investigate the contribution of butyrate in the enhanced efficacy of OIT + FOS. …”
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Thiamine-Reduced Fatigue in Quiescent Inflammatory Bowel Disease Is Linked to Faecalibacterium prausnitzii Abundance by Sandra Bermúdez-Sánchez, Palle Bager, Jens Frederik Dahlerup, Simon Mark Dahl Baunwall, Tine Rask Licht, Martin Steen Mortensen, Christian Lodberg Hvas

“…Methods: We analyzed the microbiota and short-chain fatty acids concentrations in fecal samples from patients with qIBD, with (n = 40) or without (n = 20) chronic fatigue. …”
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Morphological and Chemical Changes in the Hemolymph of the Wax Moth <i>Galleria mellonella</i> Infected by the Entomopathogenic Fungus <i>Conidiobolus coronatus</i> by Mieczysława Irena Boguś, Agata Kaczmarek, Anna Katarzyna Wrońska, Mikołaj Drozdowski, Lena Siecińska, Ewelina Mokijewska, Marek Gołębiowski

“…<i>C. coronatus</i> infection caused the appearance of 5 fatty acids absent in healthy larvae (heptanoic, decanoic, adipic, suberic, tridecanoic), the disappearance of 4 compounds (monopalmitoylglycerol, monooleoylglycerol, monostearin, and cholesterol), and changes in the concentrations of 8 compounds. …”
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Lipid mediators in post-mortem brain samples from patients with Alzheimer's disease: A systematic review by Aidan D. Tyrrell, Giulia Cisbani, Mackenzie E. Smith, Chuck T. Chen, Yue-Tong Chen, Raphael Chouinard-Watkins, Kathryn E. Hopperton, Ameer Y. Taha, Richard P. Bazinet

“…Dysregulation of lipid mediators derived from polyunsaturated fatty acids may contribute to this inflammatory response in the brain of patients with AD, yet the literature has not yet been systematically reviewed. …”
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CRISPR-Cas9-based one-step multiplexed genome editing through optimizing guide RNA processing strategies in Pichia pastoris by Kaidi Chen, Gulikezi Maimaitirexiati, Qiannan Zhang, Yi Li, Xiangjian Liu, Hongting Tang, Xiang Gao, Bo Wang, Tao Yu, Shuyuan Guo

“…Finally, we applied the system for one-step production of fatty acids and 5-hydroxytryptophan. The yield of FFAs reached 23 mg/L/μg protein/OD, while the yield of 5-hydroxytryptophan was 13.3 mg/L. …”
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Effect of Parental Migration Background on Childhood Nutrition, Physical Activity, and Body Mass Index by Mohsen Besharat Pour, Anna Bergström, Matteo Bottai, Inger Kull, Magnus Wickman, Niclas Håkansson, Alicja Wolk, Tahereh Moradi

“…They had higher intake of dietary fibre, vitamins C, B6, and E, folic acid, and polyunsaturated fatty acids (omega-3 and omega-6) reflecting higher consumption of foods of plant origin, but lower intake of vitamins A and D, calcium, and iron reflecting lower consumption of dairy products. …”
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The role of Ashwagandha in modulating gut parameters in dogs—a randomized double-blind placebo-controlled trial by Kala Kumar Bharani, Ashok Kumar Devarasetti, Rajendar Bobbili, Amit Khurana, Donga Durga Veera Hanuman, Roupesh Gudepu, Swapna Guda

“…Compared to the baseline, ARE significantly decreased two microbial metabolites, propionic acid, and total short chain fatty acids (SCFAs) levels after 60 days of intervention, whereas butyrate and acetic acid levels remained unchanged in the faecal samples.ConclusionIn summary, these findings suggest that ARE has gut health promoting benefits in healthy geriatric dogs by improving haematological and biochemical profiles; the levels of L-citrulline; propionic acid; and SCFA; thus, reducing age-related changes by modulating the microbiome and the associated metabolites.…”
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Effects of dietary xylanase-treated rice husk on performance characteristics of West African Dwarf goats Capra hircus by Isiaka Oyeniyi Kolade, Mahmud Baba Yousuf, Abiola Yemi Salako, Kamoldeen Abiodun Ajijolakewu, Tajjudeen Zakari Abdulkareem, Lawal Wasiu Sesan

“…The inclusion of xylanase-treated rice husk up to 30% in goat’s diet may have increased nutrients and dry matter digestion, total volatile fatty acids (TVFA's) and microbial protein production. …”
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Combined analysis of 16S rRNA sequencing and metabolomics reveals the growth-promoting mechanism of compound probiotics in zig-zag eel (Mastacembelus armatus) by Yuwei Feng, Zhiting Zuo, Guangting Xie, Yiman Chen, Xiaoli Yin, Baoyue Lu, Zhide Yu, Chong Han, Hu Shu

“…The compound probiotics can increase metabolites such as piperazine, phenols, glycerophospholipids, and unsaturated fatty acids. The compound probiotics can increase the number of beneficial intestinal bacteria and beneficial metabolites, promoting intestinal digestion and absorption, maintaining intestinal microbial environment homeostasis, and improving the growth of M. armatus. …”
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Structural Characterization and Antioxidant Activity in Vivo of Polysaccharides from the Leaves of Hippophae rhamnoides L. by Niannian SONG, Yuxin YI, Xiaoping ZHANG, Bo YANG, Mangsier SAINAWAER, Abuduwaili AYITUXUN

“…The medium dose group of HRLP could increase the number of gut microbiota species in mice and promote the synthesis of short-chain fatty acids in the body. In a word, HRLP may exhibit antioxidant activity by improving oxidative stress and gut microbiota in D-galactose-induced mice. …”
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Use of Dietary Supplements among Spanish Pediatricians in Daily Practice: A Cross-Sectional Survey Study by Ignacio Güemes Heras, Alicia Santamaría-Orleans, José F. Colinas Herrero, Pilar Gómez Sorrigueta, Luis Ortiz González, Raquel de la Iglesia-Arnaez, Alejandro Canals Baeza

“…They also provided data on 10 of their patients (n = 4304) in which synbiotics, immune stimulants, and omega-3 polyunsaturated fatty acids (PUFAs) had been prescribed. Synbiotics were used by 92% of pediatricians, immune stimulants by 80.4%, and omega-3 PUFAs by 75.1%. …”
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A 16-week randomized controlled trial of a fish oil and whey protein-derived supplement to improve physical performance in older adults losing autonomy-A pilot study. by Anne-Julie Tessier, Julia Lévy-Ndejuru, Audrey Moyen, Marissa Lawson, Marie Lamarche, Joseé A Morais, Amritpal Bhullar, Francis Andriamampionona, Vera C Mazurak, Stéphanie Chevalier

“…Handgrip and knee extension strength (using dynamometry), physical performance tests and plasma phospholipid n-3 fatty acids (using GCMS) were evaluated at weeks 0, 8 and 16; and lean soft tissue mass (using DXA), at weeks 0 and 16.…”
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Effect and Mechanism of Soluble Dietary Fiber from Corn Bran on Loperamide-induced Constipation in Mice by Xiangrui ZENG, Caixia JIANG, Xiaolan LIU, Xiqun ZHENG, Xuyao WEI

“…CSDF supplementation also increased the abundance of beneficial gut bacteria (Bifidobacterium, Lactobacillus, and Lachnospiraceae) and elevated levels of short chain fatty acids (SCFAs), with typical SCFAs (acetic, propionic, and butyric acids) reaching 1.89-, 1.60-, and 4.35-fold higher levels, respectively, in the L-CSDF group than that in the model group. …”
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Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome by Na Li, Chenghao Yang, Huiyu Xie, Yinghong Liu, Yuanpeng Liao

“…Compared with the NC group, the levels of testosterone (T), estradiol (E2), follicle-stimulating hormone (FSH), LP, anti-Müllerian hormone (AMH), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and free fatty acids (FFA) were all significantly augmented in the PC group (all p<0.05). …”
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Human phospholipases A2: a functional and evolutionary analysis by I. I. Turnaev, M. E. Bocharnikova, D. A. Afonnikov

“…Phospholipases A2 (PLA2) are capable of hydrolyzing the sn-2 position of glycerophospholipids to release fatty acids and lysophospholipids. The PLA2 superfamily enzymes are widespread and present in most mammalian cells and tissues, regulating metabolism, remodeling the membrane and maintaining its homeostasis, producing lipid mediators and activating inflammatory reactions, so disruption of PLA2-regulated lipid metabolism often leads to various diseases. …”
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