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1361
Gut Microbiome Modulation in Hepatocellular Carcinoma: Preventive Role in NAFLD/NASH Progression and Potential Applications in Immunotherapy-Based Strategies
Published 2025-01-01“…In this review, we summarize the main changes in the GM and derived metabolites (e.g., short-chain fatty acids and bile acids) occurring in HCC patients and influencing NAFLD progression, emphasizing their potential as early diagnostic biomarkers and prognostic tools. …”
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1362
Lysosphingolipids in ceramide-deficient skin lipid models
Published 2025-01-01“…In atopic dermatitis, pathological hydrolysis of ceramide precursors - glucosylceramides and sphingomyelin - into lysosphingolipids, specifically glucosylsphingosine (GS) and sphingosine-phosphorylcholine (SPC), and free fatty acids (FFAs) has been proposed to contribute to impaired skin barrier function. …”
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1363
The metabolomic approach to the assessment of cultivar specificity of Brassica napus L. seeds
Published 2015-07-01“…These compounds included amino acids, organic and fatty acids, tocopherols, and phytosterols. In order to keep the data assay within the context of multivariate statistics, we used principal component analysis (PCA), partial least square discriminant analysis (PLS-DA), and partial least square regression (PLS-R). …”
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1364
Comprehensive GC-MS Characterization and Histochemical Assessment of Various Parts of Three <i>Colchicum</i> Species from Bulgarian Flora
Published 2025-01-01“…Using gas chromatography-mass spectrometry (GC-MS), 66 metabolites were identified, encompassing free amino, organic, phenolic, and fatty acids, sugars, and alkaloids, which were distributed among various plant parts. …”
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1365
The Application of FT-IR Spectroscopy for Quality Control of Flours Obtained from Polish Producers
Published 2017-01-01“…An attempt was made to statistically correlate FT-IR spectral data with reference data with regard to content of various components, for example, proteins, fats, ash, and fatty acids as well as properties such as moisture, falling number, and energetic value. …”
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1366
The Gut Microbiome Regulates the Psychomotor Effects and Context-Dependent Rewarding Responses to Cocaine in Germ-Free and Antibiotic-Treated Animal Models
Published 2025-01-01“…ABX-treated mice also showed significant declines in microbial diversity, shifts in bacterial structure, and dysregulation in metabolic, immune, and neurotransmitter pathways (<i>p</i> ≤ 0.0001), including alterations in short-chain fatty acids and gamma-aminobutyric acid metabolism. …”
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1367
Recovery of Bioactive Constituents from Olive Leaf Pruning Waste of Five Different Cultivars: A Comparison of Green Extraction Techniques to Maximize Health Benefits
Published 2025-01-01“…SFE extracts with a higher concentration of fatty acids and triterpenes showed moderate antioxidant activities but very high AChE inhibition. …”
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1368
Exploring the Potential Effectiveness of <i>Croton tiglium</i> Oil and Its Nano-Emulsion on <i>Earias insulana</i> (Lepidoptera: Nolidae)
Published 2025-01-01“…Gas–liquid chromatography (GLC) identified several bioactive compounds in <i>C. tiglium</i> oil crushed dry seeds, including fatty acids, hydrocarbons, and sterols. CTNE showed excellent quality with a zeta potential of −17.7 mV, an average particle size of 54.28 nm, and spherical droplets of 42.42 nm in diameter. …”
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1369
Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis
Published 2024-12-01“…Postbiotics are bioactive metabolites such as organic acids, peptides/proteins, cell wall components, functional enzymes, short-chain fatty acids, vitamins, and phenols. These molecules mediate many positive effects such as immunomodulatory, antimicrobial, and antioxidant effects. …”
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1370
A scoping review on the use of different blood sources and components in the artificial membrane feeding system and its effects on blood-feeding and fecundity rate of Aedes aegypti...
Published 2024-01-01“…Several studies had reported that human blood was superior in blood-feeding Ae. aegypti as compared to sheep blood which resulted in lower fecundity due to accumulation of free fatty acids (FFA) in the cuticles. In contrast, cattle whole blood and pig whole blood showed no significant differences in the blood-feeding and fecundity rate as compared to human blood. …”
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1371
Options of dyslipidemia treatment at non-alcoholic fatty liver disease
Published 2018-08-01“…In the present overview treatment options of several therapeutic agents for dyslipidemia treatment at NAFLD are discussed: phenofibrate, omega-3 polyunsaturated fatty acids (omega-3-PUFAs) and S-adenosylmethionine (SAM). …”
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1372
Plasma amino acids spectrum as an important part of metabolomic pattern in patients with coronary artery disease and atrial fibrillation
Published 2023-12-01“…A strong reliable connection between plasma AA spectrum and gut microbiota metabolites (trimethylamine, trimethylamine-N-oxide, total amount of fecal short chain fatty acids) was detected.…”
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1373
Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia
Published 2023-08-01“…The major cellular fatty acids (>10.0 %) were anteiso-C15:0 (24.7 %), anteiso-C17:0 (16.4 %), iso-C16:0 (15.7 %), iso-C15:0 (11.5 %), and C16:0 (11.1 %). …”
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1374
Lipotoxicity and metabolic disorders at obesity
Published 2010-02-01“…It is possible to explain lipotoxicity phenomenon as follows: in conditions of insulin resistance glucose stops to be an energy source and is substituted by lipolysis, therefore a plenty of free fatty acids is formed, having potential of toxicity and realizing metabolic disorders in target organs: the liver, the pancreas, muscles. …”
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1375
Sex differences in the expression of lipid oxidation and glucose uptake genes in muscles of fasted mice
Published 2019-02-01“…We estimated the effect of 24-hour fasting on the expression of genes involved in lipid (Ucp3, Cpt1) and carbohydrate (Slc2a4) metabolism in muscles and evaluated changes in body weight and blood plasma levels of glucose, insulin, free fatty acids (FFA), adiponectin, and FGF21 in male and female C57BL/6J mice. …”
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1376
Effects of White Quinoa Polysaccharide on Regulation of Glucolipid Metabolism in Type 2 Diabetic Mice
Published 2025-02-01“…After four weeks of continuous feeding, the mice were dissected, and the serum indexes, liver indexes, and short-chain fatty acids (SCFAs) of the mice were determined. The intestinal contents of the mice were analyzed by 16S rRNA sequencing technology. …”
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1377
THE BENEFICIAL EFFECTS OF OLIVE TREE (OLEA EUROPAEA L.) IN THE NUTRITIONAL, PHARMACEUTICAL AND INDUSTRIAL APPLICATION: A REVIEW
Published 2024-12-01“…O. europaea also provide an excellent material of polyphenol, abundant unsaturated fatty acids and flavonoids. O. europaea seedling also possesses different types of resistance and tolerance to biotic and abiotic stress. …”
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1378
Supplementation of dairy cows with bovine somatotropin or omega-3 rich fish oil affects the endometrial expression of peroxisome proliferator-activated receptors
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1379
Metabolite Profiling of Sorghum Seeds of Different Colors from Different Sweet Sorghum Cultivars Using a Widely Targeted Metabolomics Approach
Published 2020-01-01“…We identified 651 metabolites that were divided into 24 categories, including fatty acids, glycerolipids, flavonoids, benzoic acid derivatives, anthocyanins, and nucleotides and its derivatives. …”
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1380
BREEDING FOR ANTIOXIDANT CONTENT IN GRAIN AS A PROMISING TREND IN OBTAINING HEALTHY FOOD PRODUCTS
Published 2018-05-01“…It is widely known that oat and barley grains have high nutritional value, contain unsaturated fatty acids, basic minerals, proteins and β-glucans (the highest levels among cereal crops), and are characterized by the presence of diverse chemicals with antioxidant properties. …”
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