Prebiotic Properties of Dates and Their Impact on Health by Ahmad Alhomsi, Mukaddes Kılıç Bayraktar

“…Research highlights that dates promote the growth of helpful bacteria, including Bifidobacterium and Lactobacillus, which enhance intestinal health, improve barrier function, and increase the production of short-chain fatty acids. Beyond gut health, dates offer additional benefits, including anti-inflammatory, antioxidant, cardiovascular, neuroprotective, and blood sugar-regulating effects. …”
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PPARs: Protectors or Opponents of Myocardial Function? by Christine J. Pol, Melissa Lieu, Konstantinos Drosatos

“…They can be activated by endogenous ligands, such as fatty acids, as well as by pharmacologic agents. Activators of PPARs are used for treating several metabolic complications, such as diabetes and hyperlipidemia that are directly or indirectly associated with HF. …”
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The Role of the Microbiome and Intestinal Mucosal Barrier in the Development and Progression of Non-Alcoholic Fatty Liver Disease by T. S. Krolevets, M. A. Livzan, S. I. Mozgovoy

“…The role of the human microbiome in the development and progression of NAFLD is associated with its effects on the risk factors (obesity, insulin resistance, type 2 diabetes), permeability of the intestinal barrier and absorption of such substances as short-chain fatty acids, bile acids, choline and endogenous ethanol. …”
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Influence of the extraction method on the yield and quality of bacaba palm oil from southwestern Amazonia by V.S. Álvares, J.M.L. Souza, E.J.L. Ferreira, V.T. Maciel, A.L.S. Madruga

“…The oil was stored at 26 °C and 81% RH for 365 days and analyzed for free fatty acids, peroxide value and refractive index. Artisanal extraction resulted in low oil yield and quality. …”
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Effects of highland barley β-glucan on gut microbiota composition and metabolism in vitro fermentation by Yinchen Ge, Jiaci Liu, Huacheng Tang, Yanqing Zang, Yang Cao

“…In addition, HBG increased the content of short-chain fatty acids and decreased fermentation broth pH. Metabolomics analyses showed that HBG also increased the content of beneficial metabolites such as taurine and affected amino acid metabolism, among other pathways. …”
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Treatment of Severe Hypertriglyceridemia with Continuous Insulin Infusion by Yesica Rodríguez Santana, Andrea Nimo Román, Iker García Sáez, José Manuel López Alvarez, Eduardo Consuegra Llapur, Rafael González Jorge

“…The standard treatment of hypertriglyceridemia (HTG) with omega 3 fatty acids and fibrates, along with dietary changes, has no effect on an emergency situation. …”
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Anti- and Protumorigenic Effects of PPARγ in Lung Cancer Progression: A Double-Edged Sword by Howard Li, Mary C. M. Weiser-Evans, Raphael Nemenoff

“…Ligands for PPARγ include naturally occurring fatty acids and the thiazolidinedione class of antidiabetic drugs. …”
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Gut Microbiota-Derived Metabolites in the Development of Diseases by Guangyu Shen, Jing Wu, Bang-Ce Ye, Nan Qi

“…Since high-fat and high-protein diets substantially affect the gut microbial ecology and human health, the current review summarizes the gut microbiota-derived metabolites such as short-chain fatty acids (SCFAs), amino acids, and their derivatives and highlights the mechanisms underlying the host responses to these bioactive substances.…”
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Overview of Olestra: A New Fat Substitute by Richard Hunt, Nora L Zorich, Alan BR Thomson

“…Olestra is a mixture of hexa-, hepta- and octa-esters formed from the reaction of sucrase and long chain fatty acids isolated from edible oils. Olestra has properties similar to those of traditional triglycerides but is not hydrolyzed by pancreatic lipases and, therefore, serves as a noncaloric replacement for fats in the diet. …”
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Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota by Xiaoxia He, Xiaofeng Yuan, Qilin Shu, Yayang Gao, Youli Chen, Yao Liu, Yao Liu, Yao Liu, Jian Xu, Jian Xu, Jian Xu, Yongping Zhang, Yongping Zhang, Yongping Zhang, Guoqiong Cao, Guoqiong Cao, Guoqiong Cao

“…The treatment altered levels of 39 and 38 metabolites produced during gut microbial and brain tissue metabolism respectively, mainly of amino acids, nucleosides, short-chain fatty acids, and essential fatty acids. Levels of factors related to inflammation and intestinal barrier permeability correlated positively with relative abundance of Escherichia-Shigella and Clostridium_innocuum_group, and negatively with 4-(glutamylamino) butanoate, 2-hydroxy-3-methylbutyric acid, dihomo-α-linolenic acid, dihomolinoleic acid, and 10-nitrolinoleic acid. …”
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Effect of rhGH treatment on lipidome and brown fat activity in prepuberal small for gestational age children: a pilot study by Lorena González, Carolina Gonzalez-Riano, Pablo Fernández-García, Rubén Cereijo, Aina Valls, Andrea Soria-Gondek, Nativitat Real, Belén Requena, Joan Bel-Comos, Patricia Corrales, David Jiménez-Pavón, Coral Barbas, Francesc Villarroya, David Sánchez-Infantes, Marta Murillo

“…Serum lipidomic analysis revealed that free fatty acids (FFAs) increased to levels close to those of the AGA group after three months of rhGH administration, including polyunsaturated fatty acids, correlating with reduced leptin levels. …”
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Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling by Adolf Koudelka, Gregory J. Buchan, Veronika Cechova, James P. O’Brien, Emily R. Stevenson, Crystal E. Uvalle, Heng Liu, Steven R. Woodcock, Steven J. Mullett, Cheng Zhang, Bruce A. Freeman, Stacy L. Gelhaus

“…Rather, if present in sufficient concentrations, LXA4 and other mono- and poly-hydroxylated unsaturated fatty acids synthesized by macrophages would be readily oxidized to electrophilic α,β-unsaturated ketone products that modulate the redox-sensitive cysteine proteome via G-protein coupled receptor-independent mechanisms.…”
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Selenium and Mercury Toxicity: The Tale of Fish by Razieh Farzad, Jeanette Andrade

“… Not only is fish a good source of protein, but it also provides essential fatty acids such as omega-3, vitamins such as vitamin D, and minerals such as selenium. …”
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A Comparison of Strategies to Improve Population Diets: Government Policy versus Education and Advice by Norman J. Temple

“…The removal of trans-fatty acids from food is a model for a successful action policy. …”
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Decompensation of β-Cells in Diabetes: When Pancreatic β-Cells Are on ICE(R) by Roberto Salvi, Amar Abderrahmani

“…Inappropriate induction of ICER accounts for pancreatic β-cells dysfunction and ultimately death elicited by chronic hyperglycemia, fatty acids, and oxidized LDL. This review underlines the importance of balancing the negative regulation achieved by ICER for preserving β-cell function and survival in diabetes.…”
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Expression of GPR43 in Brown Adipogenesis Is Enhanced by Rosiglitazone and Controlled by PPARγ/RXR Heterodimerization by Jiamiao Hu, Arong Zhou, Peter C. K. Cheung, Baodong Zheng, Shaoxiao Zeng, Shaoling Lin

“…GPR43, a G-protein coupled receptor recognizing short-chain fatty acids, has been reported to participate in many biological functions of white adipocytes, such as adipogenesis and lipolysis. …”
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A Spotlight on Chemical Constituents and Pharmacological Activities of Nigella glandulifera Freyn et Sint Seeds by Besma Boubertakh, Xin-Guang Liu, Xiao-Lan Cheng, Ping Li

“…In this review, we summarize the recently isolated chemical constituents from the seeds of this plant including alkaloids, flavonol glycosides, isobenzofuranone derivatives, saponins, terpenes, terpenoids, and fatty acids. We put also a spotlight on the recently studied therapeutic potentials of such amazing herb seeds as antidiabetes, melanogenesis inhibition, anticancer, anti-inflammatory, antithrombosis, and antiplatelet aggregation effects. …”
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Role of dietary and nutritional interventions in ceramide-associated diseases by Shengnan Wang, Zihui Jin, Biyu Wu, Andrew J. Morris, Pan Deng

“…Dietary interventions including the Mediterranean diet, lacto-ovo-vegetarian diet, calorie-restricted diet, restriction of dairy product consumption, and dietary supplementation with polyunsaturated fatty acids, dietary fibers, and polyphenols, all have beneficial effects on modulating ceramide levels. …”
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Quality of Cosmetic Argan Oil Extracted by Supercritical Fluid Extraction from Argania spinosa L. by Chouaa Taribak, Lourdes Casas, Casimiro Mantell, Zoubaida Elfadli, Rédouane E. Metni, Enrique J. Martínez de la Ossa

“…The argan oil extracts were characterized in terms of acid, peroxide and iodine values, total tocopherol, carotene, and fatty acids content. Significant compositional differences were not observed between the oil samples obtained using different pressures and temperatures. …”
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Study of Traditional Uses, Extraction Procedures, Phytochemical Constituents, and Pharmacological Properties of Tiliacora triandra by Gitishree Das, Sushanto Gouda, Rout George Kerry, Hernán Cortes, María L. Del Prado-Audelo, Gerardo Leyva-Gómez, Patrick Valere Tsouh Fokou, Erick P. Gutiérrez-Grijalva, J. Basilio Heredia, Han-Seung Shin, Jayanta Kumar Patra

“…Bioactive compounds contained in T. triandra include phenolic compounds, alkaloids, flavonoids, terpenoids, fatty acids, essential amino acids, peptides, carbohydrates, vitamins, and nucleic acid precursors. …”
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