Coordinated conformational changes in P450 decarboxylases enable hydrocarbons production from renewable feedstocks by Wesley Cardoso Generoso, Alana Helen Santana Alvarenga, Isabelle Taira Simões, Renan Yuji Miyamoto, Ricardo Rodrigues de Melo, Ederson Paulo Xavier Guilherme, Fernanda Mandelli, Clelton Aparecido Santos, Rafaela Prata, Camila Ramos dos Santos, Felippe Mariano Colombari, Mariana Abrahão Bueno Morais, Rodrigo Pimentel Fernandes, Gabriela Felix Persinoti, Mario Tyago Murakami, Leticia Maria Zanphorlin

“…Abstract Fatty acid peroxygenases have emerged as promising biocatalysts for hydrocarbon biosynthesis due to their ability to perform C-C scission, producing olefins - key building blocks for sustainable materials and fuels. …”
Get full text

Benefits of Virgin Coconut Oil in Diet to Colossoma macropomum (Cuvier, 1818) by Márcia Valéria Silva do Couto, Natalino da Costa Sousa, Higo Andrade Abe, Joel Artur Rodrigues Dias, Carlos Alberto Martins Cordeiro, Peterson Emmanuel Guimarães Paixão, Thays Brito Reis Santos, Fernanda dos Santos Cunha, Juliana Oliveira Meneses, Ricardo Marques Nogueira Filho, Carol Nunes Costa Bomfim, Cláucia Aparecida Honorato, Bruno Trindade Cardoso, Rodrigo Yudi Fujimoto

“…A positive control diet also prepared containing 15% lauric acid (main fatty acid in virgin coconut oil). Triplicate groups of 20 fish were fed twice daily throughout 90 days. …”
Get full text

Exploring the functional diversity and metabolic activities of the human gut microbiome in Thai adults in response to a prebiotic diet by Amornthep Kingkaw, Preecha Patumcharoenpol, Narissara Suratannon, Massalin Nakphaichit, Sittiruk Roytrakul, Wanwipa Vongsangnak

“…Consistently, across 76,206 proteins assigned to the metabolism of the 255,964 annotated proteins, short-chain fatty acid (SCFA) biosynthesis, lipopolysaccharide (LPS) biosynthesis, and bile acid (BA) metabolism were positively associated with CMH. …”
Get full text

Impact of commercial gut health interventions on caecal metagenome and broiler performance by Gladys Maria Pangga, Banaz Star-Shirko, Androniki Psifidi, Dong Xia, Nicolae Corcionivoschi, Carmel Kelly, Callie Hughes, Ursula Lavery, Anne Richmond, Umer Zeeshan Ijaz, Ozan Gundogdu

“…GHI supplementation generally affected the abundance of microbial enzymes relating to carbohydrate and protein digestion and metabolic pathways relating to energy, nucleotide synthesis, short-chain fatty acid synthesis, and drug-transport systems. These shifts are hypothesised to differentiate performance among groups and cycles, highlighting the beneficial role of several bacteria, including Rikenella microfusus and UBA7160 species. …”
Get full text

Dietary and plasma atherogenic and thrombogenic indices and cardiometabolic risk factors among overweight and individuals with obesity by Reyhaneh Mokhtari, Mahdieh Abbasalizad Farhangi

“…The study included assessments of body composition and anthropometric measurements. Dietary fatty acid consumption was evaluated using a validated Food Frequency Questionnaire (FFQ) containing 168 items. …”
Get full text

Microbial Profiles of Rhizosphere and Bulk Soil Microbial Communities of Biofuel Crops Switchgrass (Panicum virgatum L.) and Jatropha (Jatropha curcas L.) by Doongar R. Chaudhary, Jyotisna Saxena, Nicola Lorenz, Linda K. Dick, Richard P. Dick

“…The objective of this investigation was to determine the profiles of microbial communities associated with rhizosphere and bulk soils of switchgrass or jatropha using phospholipid fatty acid (PLFA) analysis and length heterogeneity PCR (LH-PCR). …”
Get full text

Comprehensive analysis of histophysiology, transcriptomics and metabolomics in goslings exposed to gossypol acetate: unraveling hepatotoxic mechanisms by Jun Yu, Jun Yu, Haiming Yang, Jian Wang, Zixin Huang, Shi Chen, Hongchang Zhao, Jun Wang, Zhiyue Wang

“…Key affected pathways included carbon metabolism, glycolysis/gluconeogenesis, pyruvate metabolism, propanoate metabolism, TCA cycle, fatty acid degradation, primary bile acid biosynthesis, tryptophan metabolism, cysteine and methionine metabolism, focal adhesion, and the PPAR signaling pathway. …”
Get full text

Soluble Receptor for Advanced Glycation End Products: A Protective Molecule against Intramyocardial Lipid Accumulation in Obese Zucker Rats? by Elena Dozio, Elena Vianello, Francesco Bandera, Erika Longhi, Stefano Brizzola, Manuela Nebuloni, Massimiliano M. Corsi Romanelli

“…Serum levels of sRAGE (total and endogenous secretory form (esRAGE)) were quantified by ELISA. Genes promoting fatty acid transport, activation, and oxidation in mitochondria/peroxisomes were upregulated in OB hearts. …”
Get full text

Hydrophobic deep eutectic solvents as novel, sustainable aids for intracellular protein release from Saccharomyces cerevisiae by Tjalling Gijsbert Tjalsma, Yannick Patrice Didion, Ziran Su, Magdalena Malankowska, Pablo Torres-Montero, José Luis Martínez, Manuel Pinelo

“…Despite the similar structures of the hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD), DESs with L-menthol and lidocaine as HBA and a fatty acid as HBD exhibited superior performance compared to DESs consisting solely of L-menthol and lidocaine or those derived from fatty acids only. …”
Get full text

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Ol... by Francis M. Finucane, Stephen J. Sharp, Mensud Hatunic, Alison Sleigh, Ema De Lucia Rolfe, Avan Aihie Sayer, Cyrus Cooper, Simon J. Griffin, David B. Savage, Nicholas J. Wareham

“…We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral glucose loading. …”
Get full text

Effects of Different Carbohydrate Levels in Diets on Growth Performance and Muscle Nutritive Value of Ying Carp and Scattered-Scaled Mirror Carp (Cyprinus carpio) by Pengfei Xiao, Yunya Wu, Hang Sha, Xiangzhong Luo, Guiwei Zou, Hongwei Liang

“…In muscle tissue, high carbohydrate diets reduced expression levels of genes involved in polyunsaturated fatty acid (PUFA) synthesis (elovl5, elovl6, and rxrgb). …”
Get full text

DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway by Hui Wang, Shen Luo, Yue Yin, Yang Liu, Xiaomei Sun, Ling Qiu, Xin Wu

“…DLAT upregulated SREBP1 expression via the JAK2/STAT5 signaling pathway, enhancing expression of fatty acid synthesis enzymes and altering lipid metabolism. …”
Get full text

Longitudinal non-targeted metabolomic profiling of urine samples for monitoring of kidney transplantation patients by Ihsan Yozgat, Ulkem Cakır, Muhittin Abdulkadir Serdar, Sevgi Sahin, Osman Ugur Sezerman, Emirhan Nemutlu, Ahmet Tarik Baykal, Mustafa Serteser

“…These distinctive metabolites mainly belonged to lipid, fatty acid, and amino acid categories. Ten models were constructed using a backward conditional approach, with the best performance seen in model 5 for Group 2 at the 1st-week mark (AUC 0.900) and model 3 at the 3rd-month mark (AUC 0.924). …”
Get full text

The quality and technological parameters of milk obtained from dairy cows with subclinical mastitis by Magdalena Zalewska, Paulina Brzozowska, Magdalena Rzewuska, Ewelina Kawecka-Grochocka, Daria M. Urbańska, Tomasz Sakowski, Emilia Bagnicka

“…Bacterial contamination did not appear to significantly affect the yield of milk or its main components, namely protein, casein, lactose, fat, TS, solid nonfat, free fatty acid, or citric acid. Although pH, freezing point depression (FPD), and acidity also remained unaffected by bacterial contamination, they were significantly influenced by herd-year-season of calving and herd-year-time of sampling interaction effects. …”
Get full text

Comparative analysis of the whole transcriptome landscapes of muscle and adipose tissue in Qinchuan beef cattle by Ju Qiu, Zheng Ma, Zhipeng Hong, Xu Yin, Yun Chen, Hafiz Qadeer Ahmed, Linsen Zan, Anning Li

“…The results of functional enrichment analysis showed that DEMs, DELs, DECs and DEmiRs were enriched in biological processes related to development and function of muscle and fat deposition, including skeletal muscle contraction, muscle organ development, PPAR signaling pathway, fatty acid metabolism and MAPK signaling pathway. Based on the competing endogenous RNA (ceRNA) regulatory mechanism, we constructed a lncRNA/circRNA-miRNA-mRNA network consisting of 6 circRNAs, 5 lncRNAs, 6 miRNAs and 27 mRNAs. …”
Get full text

Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae by Chang Liu, Yi Wei, Yuejia Dang, Wajjiha Batool, Xiaoning Fan, Yan Hu, Zhengquan He, Shihong Zhang

“…Simultaneously, as feedback to the tricarboxylic acid (TCA) cycle, the decrease of formic acid in ΔMooxdc leads to the reduction of acetyl-CoA content, and two genes involved in the β-oxidation of fatty acids were also upregulated, which enhanced the fatty acid metabolism of the ΔMooxdc. …”
Get full text

Effects of <i>Cordyceps cicadae</i> Polysaccharide on Gut Microbiota, the Intestinal Mucosal Barrier, and Inflammation in Diabetic Mice by Lijia Sun, Huaibo Yuan, Huiqing Ma, Yani Wang

“…CCPH regulates the expression of short-chain fatty acid levels, increases microbial diversity, and ameliorates mouse colon lesions by inhibiting the TLR4/NF-κB signaling pathway. …”
Get full text

Utilizing Invasive <i>Pterygoplichthys pardalis</i> as a Sustainable Fish Meal Substitute and <i>Euphorbia hirta</i> Extract Supplement: Effects on Growth Performance, Organosomati... by Sontaya Sookying, Phanit Srisuttha, Vipada Rodprasert, Chanthima Chaodon, Wikit Phinrub, Nantaporn Sutthi, Paiboon Panase

“…The analysis revealed that PPM exhibited superior amino acid profiles compared to CFM, both in quality and quantity, while CFM demonstrated higher fatty acid content. The growth metrics showed a significant decline only in the group receiving 100% PPM replacement with EHE supplementation. …”
Get full text

Comparative effects of different dietary pectin types on growth performance and intestinal health in pearl gentian grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂) by Lulu Zhu, Xiaoxue Meng, Xuehan Wang, Jiongting Fan, Beiping Tan, Junming Deng

“…Dietary 8 % CLP and ALP inclusion notably increased the relative abundance of Turicibacter and Cetobacterium in the intestine, with Turicibacter contributing to short-chain fatty acid production and Cetobacterium producing vitamin B12, both of which have positive implications for fish health. …”
Get full text

Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet by N. М. Bazhan, T. V. Jakovleva, A. Yu. Kazantseva, N. E. Kostina, P. E. Orlov, N. Yu. Balybina, K. О. Baranov, E. N. Makarova

“…Only in males, FGF21 exerted beneficial antidiabetic action: it reduced fatty acid and leptin plasma levels, improved glucose-tolerance, and upregulated hepatic expression of Ppargc1, Fasn, Accα, involved in lipid turnover, gene Insr and protein glucokinase, involved in insulin action. …”
Get full text