Hypolipidemic Effect of Hemp Seed Oil from the Northern Morocco Endemic Beldiya Ecotype in a Mice Model: Comparison with Fenofibrate Hypolipidemic Drugs by Imane Mokhtari, Yassine Taaifi, Mohamed Harnafi, Kamal Belhaj, Farid Mansouri, Reda Melhaoui, Mohamed Addi, Christophe Hano, Souliman Amrani, Hicham Harnafi, Ahmed El Amrani

“…The extraction of HSO was carried out by cold press method. Then, the fatty acid and tocopherol composition was analyzed, respectively, by GC-FID and HPLC. …”
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Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD by Ye Xu, Yuan Zhang, Wen Sun, Qiang Tang, Wanyu Feng, Hongjian Xiao, Jingjie Wang, Xinmeng Yuan, Mengqi Xiang, Yaran Gao, Hanyu Zhang, Jiao Lu

“…It was found that insulin resistance increased both the number and size of lipid droplets in the liver by enhancing the accumulation of free fatty acids, which is accompanied by an increase in contacts with mitochondria. …”
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基于现行标准实施后市售一级大豆油品质分析 "Quality analysis of commercially available grade 1 soybean oils after the national standard revision" by 陈焱1，王翔宇1，尤梦圆1，刘芯羽1，李晓龙1，孙承国2，王风艳2 " CHEN Yan1, WANG Xiangyu1, YOU Mengyuan1, LIU Xinyu1, LI Xiaolong1, SUN Chengguo2,WANG Fengyan1"

“…The mean values of the vitamin E, sterol, polyphenol and squalene contents were 113.06 mg/100 g, 3 028 mg/kg, 4.82 mg/kg and 53.71 mg/kg, respectively. The trans fatty acid content ranged from 0.25% to 0.92%. Among the 12 commercially available soybean oils, only 1 sample met the requirement of zero trans fatty acid (less than 0.3%). the content of 3-chloropropanol esters ranged from 0.23 mg/kg to 0.57 mg/kg, with an average value of 0.38 mg/kg,and the content of glycidyl esters ranged from non-detected to 3.42 mg/kg, with an average value of 1.0 mg/kg, of which the glycidyl esters content of 3 samples was higher than the EU limit. …”
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A soy glycinin derived octapeptide protects against MCD diet induced non-alcoholic fatty liver disease in mice by Peng Ma, Rongrong Huang, Yu Ou

“…To determine the effect of SGP8 on non-alcoholic fatty liver disease (NAFLD), steatosis HepG2 cells were induced by 1 mmol/L free fatty acid (FFA) and C57BL/6J mice were fed with methionine-choline deficient (MCD) diet for 3 weeks to establish NAFLD model. …”
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Gut microbial alteration in chronic spontaneous urticaria unresponsive to second generation antihistamines and its correlation with disease characteristics‐ a cross‐sectional case‐... by Indrashis Podder, David Pesqué, Nerea Carrón, Pedro Iñaki González Torres, Ramon M. Pujol, Ana M. Giménez‐Arnau

“…CSU patients showed reduced load of short‐chain fatty acid (SCFA) producing microbiota and increased load of opportunistic pathogens. …”
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Growing Chlorella vulgaris in Photobioreactor by Continuous Process Using Concentrated Desalination: Effect of Dilution Rate on Biochemical Composition by Ângelo Paggi Matos, Regina Coeli de Oliveira Torres, Luiz Rodrigo Ito Morioka, Elisa Helena Siegel Moecke, Kepler Borges França, Ernani Sebastião Sant’Anna

“…These fatty acids present 14 to 18 carbons in the carbon chain, being mainly saturated and polyunsaturated, respectively. …”
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Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition by Yongkang Liu, Fan Yang, Sijing Wan, Xianzhong Wang, Liwen Guan, Yan Li, Caidi Xu, Binghua Xie, Shigui Wang, Xiao-Ling Tan, Bin Tang

“…The overlapping DEGs were implicated in various biological processes, including protein metabolism, fatty acid metabolism, AMPK signaling, mTOR signaling, insulin/insulin-like growth factor signaling (IIS), the tricarboxylic acid (TCA) cycle, oxidative phosphorylation, and the cellular process of meiosis in oocytes. …”
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Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice by Sorim Choung, Kyong Hye Joung, Bo Ram You, Sang Ki Park, Hyun Jin Kim, Bon Jeong Ku

“…In addition, the HL group significantly decreased the hepatic expression of genes associated with lipid synthesis, cholesterol biosynthesis, and lipid droplet development and increased the hepatic expression of genes associated with fatty acid β-oxidation, thus suggesting that lobeglitazone decreased hepatic steatosis and reversed hepatic lipid dysregulation. …”
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Sunflower lines originated from varieties with high oil content in their seed by V. A. Gavrilova, I. N. Anisimova, T. G. Stupnikova

“…Mutants with modified fatty acid composition were obtained, and high oleic cultivar 'Pervenets' was created. …”
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Effects of Ghrelin on Triglyceride Accumulation and Glucose Uptake in Primary Cultured Rat Myoblasts under Palmitic Acid-Induced High Fat Conditions by Lingling Han, Jia Li, Ying Chen, Wei Wang, Dan Zhang, Guoliang Liu

“…These effects may involve fatty acid oxidation.…”
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Intermediate MCAD Deficiency Associated with a Novel Mutation of the ACADM Gene: c.1052C>T by Holli M. Drendel, Jason E. Pike, Katherine Schumacher, Karen Ouyang, Jing Wang, Mary Stuy, Stephen Dlouhy, Shaochun Bai

“…Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive disorder that leads to a defect in fatty acid oxidation. ACADM is the only candidate gene causing MCAD deficiency. …”
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Harmonious regulation flavor and lipid oxidation in dry-cured tenderloin through electrical stimulation: A study on lipase activity and sensory correlations by Lisha Lan, Li Chen, Xiaolin Zhong, Weiguo Cao, Ying Zhou, Jing Wan, Yuanyuan Liu, Qinjin Zhu

“…Compared to the control group, the electrically stimulated samples exhibited higher total amino acid and fatty acid contents. Furthermore, the electrically stimulated group demonstrated superior taste (as assessed by an electronic tongue) and aroma profiles (as assessed by an electronic nose). …”
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Alpha-linolenic acid-mediated epigenetic reprogramming of cervical cancer cell lines by Amrita Ulhe, Prerna Raina, Amol Chaudhary, Ruchika Kaul-Ghanekar

“…In this work, we have evaluated the potential of ALA (α linolenic acid), an ω-3 fatty acid, to regulate cervical cancer through epigenetic mechanisms. …”
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Protein and metabolite acclimations to temperature variability in a calcareous green macroalga Halimeda macroloba by Hao Zhang, Yuyu Wang, Lingshuai Zhang, Zhiqin Wang, Zejun Zhu, Lijuan Long, Lijuan Long

“…At the sub-optimal temperature of 25°C, the alga modulated its fatty acid composition to maintain membrane fluidity and accumulated selenium-containing metabolites to mitigate oxidative stress. …”
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Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD by Charles I. V. Drummer, Fatma Saaoud, Yu Sun, Diana Atar, Keman Xu, Yifan Lu, Ying Shao, Candice Johnson, Lu Liu, Huimin Shen, Nirag C. Jhala, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

“…We performed a panoramic analysis on both human nonalcoholic steatohepatitis (NASH) microarray data and microarray/RNA-seq data from various mouse models of nonalcoholic fatty liver disease NASH/NAFLD with total 4249 genes examined and made the following findings: (i) human NASH and NAFLD mouse models upregulate both cytokines and chemokines; (ii) pathway analysis indicated that human NASH can be classified into metabolic and immune NASH; methionine- and choline-deficient (MCD)+high-fat diet (HFD), glycine N-methyltransferase deficient (GNMT-KO), methionine adenosyltransferase 1A deficient (MAT1A-KO), and HFCD (high-fat-cholesterol diet) can be classified into inflammatory, SAM accumulation, cholesterol/mevalonate, and LXR/RXR-fatty acid β-oxidation NAFLD, respectively; (iii) canonical and noncanonical inflammasomes play differential roles in the pathogenesis of NASH/NAFLD; (iv) trained immunity (TI) enzymes are significantly upregulated in NASH/NAFLD; HFCD upregulates TI enzymes more than cytokines, chemokines, and inflammasome regulators; (v) the MCD+HFD is a model with the upregulation of proinflammatory cytokines and canonical and noncanonical inflammasomes; however, the HFCD is a model with upregulation of TI enzymes and lipid peroxidation enzymes; and (vi) caspase-11 and caspase-1 act as upstream master regulators, which partially upregulate the expressions of cytokines, chemokines, canonical and noncanonical inflammasome pathway regulators, TI enzymes, and lipid peroxidation enzymes. …”
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The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model by Denisa Miklankova, Irena Markova, Martina Hüttl, Barbora Stankova, Hana Malinska

“…Introduction. Monounsaturated fatty acids (MUFA) are understood to have therapeutic and preventive effects on chronic complications associated with type 2 diabetes mellitus (T2DM); however, there are differences between individual MUFAs. …”
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Exploitation of the Nutraceutical Potential of the Infesting Seaweed <i>Chaetomorpha linum</i> as a Yellow Mealworms’ Feed: Focus on Nutrients and Antioxidant Activity by Annalaura Brai, Edoardo Brogi, Franca Tarchi, Federica Poggialini, Chiara Vagaggini, Sauro Simoni, Valeria Francardi, Elena Dreassi

“…Analysis of the secondary metabolites revealed a better fatty acid composition, rich in PUFA, with lipid nutritional indexes comparable to seaweeds and crabs. …”
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The Protective Effect of Docosahexaenoic Acid on Mitochondria in SH-SY5Y Model of Rotenone-Induced Toxicity by Britta Eggers, Jennifer Stepien, Anne-Katrin Reker, Svenja Esser, Kathy Pfeiffer, Magdalena Pawlas, Katalin Barkovits, Katrin Marcus

“…<b>Background:</b> Polyunsaturated fatty acids in particular omega-3 fatty acids, such as docosahexaenoic acid (DHA), are essential nutrients and components of the plasma membrane. …”
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Polyphenols of <i>Perilla frutescens</i> of the family Lamiaceae identified by tandem mass spectrometry by M. P. Razgonova, N. G. Kon’kova, A. M. Zakharenko, K. S. Golokhvast

“…There were hydroxycoumarin Umbelliferone; triterpene Squalene; omega-3 fatty acid Stearidonic [Moroctic] acid; higher-molecular-weight carboxylic acid: Tetracosenoic acid and Salvianic acid C; lignan Syringaresinol and cyclobutane lignan Sagerinic acid, etc. …”
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Effect of double-induced on whey protein isolate nanoparticle formation and stabilized food-grade Pickering emulsions: Stability and gastrointestinal digestion by Shenghua He, Yonghui Wang, Guanghui Li, Xueli Gao, Zhiyan Chen, Weiyun Guo, Jihong Huang

“…PEs stabilized by double-induced WPINs showed a slower release rate of free fatty acid during gastrointestinal digestion. These findings highlight the promising application potential of WPINs in food-grade Pickering emulsion.…”
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