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741
Transcriptional Activity of PGC-1α and NT-PGC-1α Is Differentially Regulated by Twist-1 in Brown Fat Metabolism
Published 2012-01-01“…Overexpression of Twist-1 in brown adipocytes suppresses transcription of a subset of PGC-1α-target genes involved in mitochondrial fatty acid oxidation and uncoupling (CPT1β, UCP1, and ERRα). …”
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742
Enhanced stability and oxidation resistance of Acer truncatum Bunge seed oil Pickering emulsion using rice bran protein modified by phytic acid
Published 2025-01-01“…The potential applications of Acer truncatum Bunge seed oil in the food and medical industries are constrained by its susceptible fatty acid composition, which is prone to oxidation. …”
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743
Proteomic analysis of whole blood to investigate the therapeutic effects of nervonic acid on cerebral ischemia-reperfusion injury in rats
Published 2025-01-01“…Nervonic acid (NA), a vital long-chain monounsaturated fatty acid found in mammalian nervous tissue, shows promising therapeutic potential in neurological disorders. …”
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744
Preparation of a Low-Calorie, Gluten-Free All-in-One Cake Mix, Containing Bacillus Coagulans Using Quinoa and Inulin Functionality
Published 2022-01-01“…Its amino acid profile, fatty acid profile, and peroxide index were determined. …”
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745
Wheat Germ as Partial or Total Substitutive of Lean Meat in Low-Fat Cooked Sausages
Published 2025-01-01“…Proximal composition, color, texture, emulsion characterization, fatty acid profile, fat oxidation, and consumer acceptance were then analyzed. …”
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746
Relative validity and reproducibility of a short semi-quantitative food frequency questionnaire for Chinese athletes.
Published 2025-01-01“…Omega-3 polyunsaturated fatty acid (EPA, DHA, and EPA+DHA) intake estimated from the FFQ significantly correlated with corresponding serum biomarkers, with CCs ranging from 0.389 to 0.520. …”
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747
Target miRNA identification for the LPL gene in large yellow croaker (Larimichthys crocea)
Published 2025-02-01“…Quantitative PCR assays suggested that miR-84a and miR-1231-5p might influence LPL expression during the starvation phase, intimating the regulatory role of miRNA in fatty acid metabolism within hepatic and muscular tissue under starvation. …”
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748
Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress
Published 2025-01-01“…Non-targeted metabolomics analysis identified that the combinatory exposure group exhibited greater fluctuations in metabolite content, particularly in triacylglycerol, fatty-acid, peptide and amino acid. Moreover, H. pylori infection and arsenic exposure had increased levels of metabolites associated with the intestinal microbiota in their livers (4-Ethylphenyl sulfate and Phenylacetylglycine). …”
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749
Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress
Published 2025-01-01“…The results indicated that BPS could inhibit the mRNA expression of PPARα and carnitine palmitoyl transferase 1B (CPT1B), reduce lipid metabolism, promote mRNA or protein expression of SREBP1C and fatty acid synthase (FASN), and increase lipid synthesis. …”
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750
AI-enhanced 3D-QSAR screening of fragment-based novel designed molecules targeting Phalaris minor ACCase
Published 2025-06-01“…Acetyl-CoA carboxylase (ACCase: EC 6.4.1.2) is a crucial enzyme for fatty acid synthesis in plants, particularly in the Graminae family, making it an ideal target for herbicides aimed at selective weed control in agriculture. …”
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751
Comparative Study on the Effects of Four Plant Protein Sources on the Liver and Intestinal Health of Largemouth Bass, Micropterus salmoides
Published 2024-01-01“…The contents of total bile acid, lipid, and collagen in the liver were increased, and the mRNA expression levels of genes encoding inflammatory factors and enzymes involved in de novo fatty acid synthesis and bile acid synthesis were upregulated. …”
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752
In vivo Metabolic Investigation of Oxygen, Light, and Temperature Effects on Dormancy Alleviation of Sesame (Sesamum indicum L.) Seeds
Published 2025-01-01“…When exposed to continuous light at 15 °C, under anaerobic or aerobic conditions, changes in metabolic resonances were observed through spectroscopy, indicating moisture and fatty acid transfer between seed structures. Despite these changes, magnetic resonance imaging showed that the embryo did not develop. …”
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753
Data Mining Evidences Variabilities in Glucose and Lipid Metabolism among Fish Strains: A Case Study on Three Genotypes of Gibel Carp Fed by Different Carbohydrate Sources
Published 2023-01-01“…Interestingly, Dongting showed upregulation of genes involved in glycolysis and fatty acid oxidation in muscle. Furthermore, there were numerous interactions between carbohydrate sources and strains for growth, metabolites, and transcriptional control, confirming the existence of genetic polymorphisms in carbohydrate use in gibel carp. …”
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754
Differentially expressed whey proteins of donkey and bovine colostrum revealed with a label-free proteomics approach
Published 2023-07-01“…Metabolic pathway analysis suggested that the majority of the DEWPs were associated with soluble NSF factor attachment protein receptor interactions in vesicular transport, fatty acid biosynthesis, and estrogen signaling pathways. …”
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755
The Alteration of Carnitine Metabolism in Second Trimester in GDM and a Nomogram for Predicting Macrosomia
Published 2020-01-01“…The present study is aimed at evaluating carnitine alteration in fatty acid metabolism in the second trimester of pregnancy and the correlation between carnitine and GDM. …”
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756
The PI4K2A gene positively regulates lipid synthesis in bovine mammary epithelial cells and attenuates the inhibitory effect of t10,c12-CLA on lipid synthesis
Published 2025-01-01“…The results revealed that PI4K2A plays a crucial regulatory role within the cytoplasm of BMECs, positively impacting fatty acid (FA) transport, triacylglycerol (TAG) synthesis, and lipid droplet secretion (p < 0.05 for all effects). …”
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757
The Optimization of the Debittering Process and the Exploration of Bitter Metabolites of <i>Paeonia ostii</i> ‘Fengdan’ Seeds
Published 2025-01-01“…We first optimized the debittering process by orthogonal experiments which reduced the polyphenol content by 90.25%, and we measured the main nutritional value of fatty acid composition, indicating that the high content of ALA is not affected by debittering. …”
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758
Enhancing the bioaccessibility and stability of curcumin through the formation of curcumin-piperine complexes in delivery systems based on nanoemulsions stabilized with phospholipi...
Published 2025-06-01“…The curcumin and astaxanthin bioaccessibility, antioxidant capacity, and fatty acid release were also evaluated in both the gastric and intestinal phases using an in vitro model. …”
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759
Radix Astragali Improves Dysregulated Triglyceride Metabolism and Attenuates Macrophage Infiltration in Adipose Tissue in High-Fat Diet-Induced Obese Male Rats through Activating m...
Published 2014-01-01“…Increased levels of free fatty acids (FFAs) and hypertriglyceridemia are important risk factors for cardiovascular disease. …”
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760
Minimization of the Bacillus subtilis divisome suggests FtsZ and SepF can form an active Z-ring, and reveals the amino acid transporter BraB as a new cell division influencing fact...
Published 2025-01-01“…After extensive phenotypic testing of these mutations, we found an unexpected cell division regulation function for the branched chain amino acid transporter BraB, which may be related to a change in fatty acid composition. The implications of these findings for the role of SepF, and the construction of a minimal cell division machinery are discussed.…”
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