Trends in Survival for Adult Organ Transplantation by Grant Patrick, BS, Brian Hickner, MD, Karthik Goli, BS, Liam D. Ferreira, MBA, John Goss, MD, Abbas Rana, MD

“…Many studies have shown progress in waitlist and post-transplant survival for adult kidney, liver, heart, and lung transplants, but there is a need to provide a more comprehensive perspective of transplant outcomes for patients and their families. Methods:. Univariable and multivariable Cox regression analyses were used to analyze factors contributing to intent-to-treat survival in 813,862 adults listed for kidney, liver, heart, and lung transplants. …”
Get full text

ARBUSCULAR MYCORIRRHIZAL RESPONSE OF FIVE OLIVE (OLEA EUROPAEA L.) INTRODUCED TO AN ARID ZONE IN ALGERIA by Bouabdelli Zahra Robã, Doghbage Abdelghafour, Hafidh Zemour, Walid Soufan, Fathi Abdellatif Belhouadjeb

“…In the rhizospheric soil, 11 species belonging to seven genera, three families, two orders and one class AMF were morphologically identified: Septoglomus constrictum, Septoglomus deserticola, Funneliformis mosseae, Funneliformis fasciculatum, Funneliformis coronatum, Funneliformis geosporum. …”
Get full text

Representing and Quantifying Conformational Changes of Kinases and Phosphatases Using the TSR-Based Algorithm by Tarikul I. Milon, Krishna Rauniyar, Sara Furman, Khairum H. Orthi, Yingchun Wang, Vijay Raghavan, Wu Xu

“…This study results in several major findings as follows: (i) The clustering method yields functionally coherent clusters of kinase and phosphatase families and their superfamilies. (ii) Specific TSR keys are identified as structural signatures for different types of kinases and phosphatases. …”
Get full text

Study of subterranean biodiversity of the upper Neretva River catchment in Bosnia and Herzegovina by Maja Zagmajster, Ester Premate, Špela Borko, Behare Rexhepi, Vojo Milanović, Anton Brancelj, Michaela Brojer, Christophe Douady, Josef Grego, Milica Jovanović, Florian Malard, Nataša Mori, Vladimir Pešić

“…Of the latter, four species were distinguished based on morphology: two species of snails from the families Hydrobiidae and Moitessieriidae, one representative of Ostracoda and one Copepoda. …”
Get full text

Programmes to support transitions in community care for children with complex care needs: a scoping review by Shelley Doucet, Jennifer Splane, Patricia Charlton, Alison Luke, Janet A Curran, Christine Cassidy, Sydney Breneol, Shelley McKibbon, Holly McCulloch, Jessie-Lee McIsaac, Angela Riveroll

“…Objective This scoping review aimed to map the range of programmes in the literature to support children and youth with complex care needs and their families during transitions in care in the community.Design A scoping review of the literature.Context This review included programmes that supported the transition in care to home and between settings in the community.Data sources We implemented our strategy to search five databases: (1) PubMed; (2) CINAHL; (3) ERIC; (4) PyscINFO and (5) Social Work Abstracts. …”
Get full text

Effects of orally administered clioquinol on the fecal microbiome of horses by Mikaila Z. Smith, Mary York, Kile S. Townsend, Lynn M. Martin, Tamara Gull, Lyndon M. Coghill, Aaron C. Ericsson, Philip J. Johnson

“…Conclusions Clioquinol has broad‐spectrum antibacterial effects on the fecal microbiome of horses, but spares certain bacterial families including several pathogens and pathobionts. …”
Get full text

Clinical characteristics, complications and satisfaction of megameatus intact prepuce (MIP) hypospadias variant: a 15 year retrospective study by Meng He, Songqiao Fan, Ning Sun, Jun Tian, Minglei Li, Hongcheng Song, Weiping Zhang

“…All enrolled patients underwent telephone follow-up and a survey was conducted on the satisfaction of patients and their families. Outcome analysis was focused on clinical data includes age, position of the meatus, penile curvature, type of repair, complications and satisfaction survey results. …”
Get full text

Mindfulness-based retreat for mothers of paediatric heart transplant recipients: protocol for a pilot intervention study by Sara Ahola Kohut, Joanna Mitchell, Samantha J Anthony, Taylor Robertson, Heather Telfer, Mirna Seifert-Hansen

“…Given that a mother’s ability to successfully cope with the demands of her caregiving role may be predictive of positive familial psychosocial outcomes, it is critical that maternal coping is assessed and supported in paediatric healthcare. …”
Get full text

Developing a new clinical governance framework for chronic diseases in primary care: an umbrella review by Walter Ricciardi, Gianfranco Damiani, Alessandra Buja, Vincenzo Baldo, Mark H Ebell, Roberto Toffanin, Mirko Claus

“…Interventions for patients and their families should focus on their values; on clinical, professional and institutional integration and finally on accountability to patients, peers and society at large. …”
Get full text

Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…The cause of ALS is largely unknown, with 90% of cases being sporadic and 10% familial. Current research targets molecular mechanisms of inflammation, excitotoxicity, aggregation-prone proteins, and proteinopathy. …”
Get full text

Transition from pediatric to adult health services: A survey of challenges, needs, and preferences of youths and parents by Eric Racine, François Ouimet, Rocio Gissel Gutierrez Rojas, Marie-José Clermont, Anne Fournier

“…Recommendations have pointed to greater preparation of youths and families and better coordination. Considerations such as patient values and preferences may – if not taken into consideration – impede uptake of clinical recommendations. …”
Get full text

Biodiversity of Non-<i>Apis</i> Bees (Hymenoptera: Apoidea) in the Potohar Region of Pakistan by Sumera Aslam, Muhammad Naeem, Sabir Hussain, Maryam Riasat, Muhammad Ather Rafi, Ahmed Zia, Muhammad Khalid Rafique, Nawaz Haider Bashir, Huanhuan Chen

“…A total of 2005 specimens, representing 27 species from 13 genera and five families (Apidae, Halictidae, Colletidae, Megachilidae, and Andrenidae), were collected over 24 surveys conducted between 2012 and 2015. …”
Get full text

First Look at the Venoms of Two <i>Sinomicrurus</i> Snakes: Differences in Yield, Proteomic Profiles, and Immunorecognition by Commercial Antivenoms by Xiang-Yu Li, Ya-Qi Zhang, Xin-Ru Qian, Hong-Yan Zhao, Hong-Liang Lu, Jian-Fang Gao

“…The venoms of these two species varied in their electrophoretic profiles, as well as in the presence or absence and relative abundance of protein families. They exhibited a 3-FTx-predominant phenotype, where the <i>S. maccelellandi</i> venom was dominated by 3-FTx (32.43%), SVMP (23.63%), PLA₂ (19.88%), and SVSP (12.61%), while the <i>S. kelloggi</i> venom was dominated by 3-FTx (65.81%), LAAO (11.35%), and AMP (10.09%). …”
Get full text

The development of initial material of spring common wheat for breeding for resistance to stem rust (Puccinia graminis Pers. f. sp. tritici), uncluding race Ug99, in Russia by I. F. Lapochkina, O. A. Baranova, V. P. Shamanin, G. V. Volkova, N. R. Gainullin, A. V. Anisimova, D. N. Galinger, E. N. Lazareva, E. V. Gladkova, O. F. Vaganova

“…While developing hybrids with the spring mode of life, donor of resistance 113/00i-4 (Sr2, Sr36, Sr39, Sr40, Sr44, Sr47) and accession 145/05i, which is resistant to leaf rust under the conditions of the RF Central Region but susceptible to Ug99, were used for backcrossing, 137 individual plants with the homozygotic state of alleles of 2–5 genes of resistance to stem rust were selected from the obtained hybrid families F4–F5 and backcross progeny BC1F3-BC2F2-BC3F2 by means of molecular markers. …”
Get full text

Protocol for the implementation evaluation of an integrated paediatric and primary care model: Strengthening Care for Children (SC4C) by Yvonne Zurynski, Susan Woolfenden, Peter D Hibbert, Harriet Hiscock, Raghu Lingam, Karen Wheeler, Michael Hodgins, Jade Burley, Rachel Pelly, Jane Le, Sonia Khano, Tammy Meyers Morris, Stephanie Germano

“…Data collection will be via questionnaires and semistructured interviews with general practitioners, paediatricians, general practice administrative staff and children and families. Each of the 21 general practices recruited into the study will be described in terms of staffing, patient throughput and location, in addition to the nuanced inner and outer contexts, use of the intervention and its acceptability. …”
Get full text

Observational study protocol: the faecal microbiome in the acute stage of new-onset paediatric type 1 diabetes in an Irish cohort by Eugene Dempsey, Catherine Stanton, Paul Ross, Colin Patrick Hawkes, Aonghus Lavelle, Carol-Anne O’Shea, Elaine Catherine Kennedy, Fiona Catherine Ross

“…Study results will be available to patients with T1D and their families, carers, support networks and microbiome societies and other researchers.Trial registration number The clinicaltrials.gov registration number for this trial is NCT06157736.…”
Get full text

Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study by Rahamat Unissa Syed, Sivakumar S. Moni, Weiam Hussein, Taghreed Mohammad Saad Alhaidan, Sondos Mohammed Y. Abumilha, Lama Khalid Alnahdi, Ling Shing Wong, Vetriselvan Subramaniyan, Vinoth Kumarasamy

“…Abstract Cubebin, a dibenzyl butyrolactone lignan belonging to several distinct families, including Aristolochiaceae, Myristicaceae, Piperaceae, and Rutaceae, and possesses several pharmacological activities, including analgesic, anti-inflammatory, antioxidant, and vasodilatory. …”
Get full text

Molecular Insights Into the Sensory Adaption of the Cave‐Dwelling Leech Sinospelaeobdella wulingensis to the Karst Cave Environment by Xi Wen, Haiyang Xiang, Mengqing Zhang, Aoran Yan, Dongqing Xiang, Jie Zou, Yue Zhang, Xinglong Huang, Zhixiao Liu

“…These channels/receptors are transmembrane proteins sharing conserved structural features in the respective protein families. SwPiezo1 shares high identity with Piezos in non‐caving leeches. …”
Get full text

Outcomes of Patients Who Have Do Not Resuscitate Status prior to Being Admitted to an Intensive Care Unit by Debjit Saha, Carlos Moreno, Marc Csete, Elizabeth Kury Perez, Luigi Cubeddu, David Farcy, Steven Henry, Zachary Glazer, Lisa A. Moreno-Walton, Robert C. Goldszer

“…Our study supports the need for less expensive and less intensive but more appropriate resources for patients and families who have chosen DNR status.…”
Get full text

Haploidentical hematopoietic stem cell transplantation using post-transplant cyclophosphamide in patients with inborn errors of immunity: Experience in a reference center in Colomb... by Diego Medina, Jhonier Orlando Castro, David Esteban Castro, Estefanía Beltrán, Eliana Manzi, Alexis Antonio Franco, Manuela Olaya

“…Sixteen patients with haploidentical familial donor transplantation were included. The most frequent diagnosis was severe combined immunodeficiency (n=5). …”
Get full text