Alpha synuclein and inflammaging by Geneviève L. Putnam, Robert W. Maitta

“…Regarding abnormal α-syn, a number of autosomal dominant mutations have been identified as causes of familial PD, however, symptomatology may not become apparent until later in life due to compensatory mechanisms in the dopaminergic response. …”
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Molecular Phylogenetic Relationships Based on Mitogenomes of Spider: Insights Into Evolution and Adaptation to Extreme Environments by Rongxiang Zhang, Niyan Xiang, Xiaoman Gao, Guiyu Zhang, Tian Lu, Tao Yuan

“…Codon usage frequencies were similar between families and codon usage in the mitogenome of spiders was mainly influenced by natural selection pressures rather than G/C mutation bias. …”
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Evaluation on Antidiabetic Properties of Medicinal Plants from Myanmar by Dongdong Zhang, Karuppusamy Arunachalam, Yuehu Wang, Yu Zhang, Jun Yang, Pyae Phyo Hein, Aye Mya Mon, Jianwen Li, Angkhana Inta, Xuefei Yang

“…Hydroalcoholic extracts of 130 medicinal plants belonging to 66 families were evaluated using porcine pancreatic lipase (PPL) inhibition and glucose uptake methods together with a literature review. …”
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The Relationship between Health-Promoting Behaviors and Resilience in Patients with Chronic Kidney Disease by Li-Ching Ma, Hong-Jer Chang, Yueh-Min Liu, Hsiang-Li Hsieh, Lan Lo, Mei-Yu Lin, Kuo-Cheng Lu

“…Therefore, nursing education should focus on health promotion advocacy throughout the life of not only patients but also their families.…”
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Ecological and Functional Changes in the Hindgut Microbiome of Holstein Cows at High Altitudes by Gong Chen, Haibo Lu, Shangzhen Huang, Congcong Zhang, Xiaojuan Ma, Bin Li, Lingling Hou, Qing Xu, Yachun Wang

“…Furthermore, we identified four key microbial taxa, the <i>Bacteroidaceae</i> and <i>Rikenellaceae</i> families, as well as the <i>Prevotella</i> and <i>Treponema</i> genera, which were associated with the regulation of carbohydrate digestion and energy metabolism and might help the Holstein cows adapt to the plateau environment. …”
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Does Quantitative Research in Child Maltreatment Tell the Whole Story? The Need for Mixed-Methods Approaches to Explore the Effects of Maltreatment in Infancy by Samuel Glass, Ruchika Gajwani, Fiona Turner-Halliday

“…This mixed-methods study of maltreated children (N=92) entering care (age 6–60 months) combines a quantitative focus on the associations between care journey characteristics and mental health outcomes with a qualitative exploration of maltreatment in four different families. Methods. Care journey data was obtained from social care records; mental health and attachment assessments were carried out following entry to care; qualitative data comprised semistructured interviews with professionals, foster carers, and parents. …”
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Transient Neonatal Zinc Deficiency Caused by a Heterozygous G87R Mutation in the Zinc Transporter ZnT-2 (SLC30A2) Gene in the Mother Highlighting the Importance of Zn2+ for Normal... by Maria Consolata Miletta, Andreas Bieri, Kristin Kernland, Martin H. Schöni, Vibor Petkovic, Christa E. Flück, Andrée Eblé, Primus E. Mullis

“…More than 20 zinc transporters characterized up to date, classified into two families (Slc30a/ZnT and Slc39a/Zip), reflect the complexity and importance of maintaining cellular Zn2+ homeostasis and dynamics. …”
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Th1 and Th2 cytokine profile in patients with early onset periodontitis and their healthy siblings by Jiřina Bártová, Zuzana Krátká-Opatrná, Jarmila Procházková, Otakar Krejsa, Jana Dušková, Lubor Mrklas, Helena Tlaskalová, Božena Cukrowská

“…Early onset periodontitis (EOP) is a chronic inflammatory periodontal disease with a strong genetic link affecting individuals aged 17 to 25. In the familial studies we tested the hypothesis about the role of Th1 and Th2 cytokines in the pathogenesis of EOP disease. …”
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The Prevalence of Using Traditional, Complementary, and Integrative Medicine by Patients with Epidermolysis Bullosa by Mohammad Mahdi Parvizi, Nasrin Saki, Ehsan Amiri-Ardekani, Parisa Ahmadfard, Mehdi Pasalar

“…In this regard, 79.4% of the patients used TCIM by themselves or their families to manage EB. Approximately, half of the patients were not aware of the effects of the herbal medicines they used. …”
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Ethical Issues in Uncontrolled Donation After Circulatory Determination of Death: A Scoping Review to Reveal Areas of Broad Consensus, and Those for Future Research by Anastasia Georgiou, Weiyi Tan, Mihnea I. Ionescu, Isla L. Kuhn, Zoe Fritz

“…Broad consensus was identified on several issues including: decisions about termination of resuscitation and entry into a uDCD protocol should be made by different teams; at least 20–30 min of cardio-pulmonary resuscitation is required; a hands-off period of 5–7 min is required alongside continuous monitoring; organ preserving techniques should be as minimally invasive as possible; families should be approached early to discuss organ donation by trained staff; public knowledge and engagement about uDCD is poor and must be improved; transparency and informed consent are essential for potential uDCD organ recipients. …”
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Frequency and Significance of Abnormal Pancreatic Imaging in Patients with BRCA1 and BRCA2 Genetic Mutations by Elie Chahla, Antonio Cheesman, Suzanne M. Mahon, Robert W. Garrett, Ben P. Bradenham, Theresa L. Schwartz, Louay Omran, Jason R. Taylor, Samer Alkaade

“…Although the majority of cases are believed to occur sporadically, about 10% show familial clustering and studies have identified an increased frequency of BRCA germline mutations. …”
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Prevalence and associated factors of probable depression amongst pregnant and parenting young females: a comparison of adolescents and young adults in rural South Africa by K. P. Seakamela, R. G. Mashaba, C. B. Ntimana, M. O. Mbombi, J. Tlouyamma, J. Tlouyamma, P. Mphekgwana, R. Nemuramba, K. Mothapo, L. Muthelo, L. N. Mabila, I. Dhau, E. Maimela, E. Maimela

“…The prevalence of unplanned pregnancy in the present study was 81.8%.ConclusionFurthermore, the present study indicated that participants from low socio-economic status families and those who were HIV positive were at a greater risk of depression in both groups. …”
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Deciphering TCOF1 mutations in Chinese Treacher Collins syndrome patients: insights into pathogenesis and transcriptional disruption by Zhuoyuan Jiang, Ke Mao, Bingqing Wang, Hao Zhu, Jiqiang Liu, Ruirui Lang, Baichuan Xiao, Hailin Shan, Qi Chen, Ying Li, Shouqin Zhao, Qingguo Zhang, Huisheng Liu, Yong-Biao Zhang

“…Results To address this, we performed mutation screening on a familial TCS case (trio) and 11 sporadic cases from a Chinese population. …”
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Positron Emission Tomography—Computer Tomography Scan Used as a Monitoring Tool Following Cellular Therapy in Cerebral Palsy and Mental Retardation—A Case Report by Alok Sharma, Hemangi Sane, Amruta Paranjape, Nandini Gokulchandran, Pooja Kulkarni, Anjana Nagrajan, Prerna Badhe

“…Even after lifelong medical and therapeutic management there are residual deficits which affect the quality of life of the patients and their families. We examined a maximally rehabilitated, 20 year old male suffering from CP and Mental Retardation (MR). …”
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MicroRNA Deregulation in Anaplastic Thyroid Cancer Biology by Cesar Seigi Fuziwara, Edna Teruko Kimura

“…However, specific miRNAs are downregulated in ATC, such as those of the miR-200 and miR-30 families, which are important negative regulators of cell migration, invasion, and epithelial-to-mesenchymal transition (EMT), processes that are overactivated in ATC. …”
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Burden of Respiratory Syncytial Virus Hospitalizations in Canada by Ian Mitchell, Isabelle Defoy, ElizaBeth Grubb

“…Results. 13.4% of all infants (n = 67) had intensive care unit (ICU) admission, and average ICU stay for these infants was 6.5 days. Families had average out-of-pocket expenses of 736.69 Canadian dollars (CAD $), and the average time both parents spent in hospital was nearly 7 days (164.0 hours). …”
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Effect of Using Building Maintenance Information Management System in Maintenance Process in Ministry of Education by Twana Abdullah Hussein, Ahmet Oztas

“…Educational buildings and Schools are one of the important facilities in community directly related to all families and any problems in the buildings affect the learning process, in Kurdistan according to the latest status about 60% of schools need maintenance and renovations and these data’s needs to manage properly. …”
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Hikikomori, a risk factor for life-threatening malnutrition: a case report of an emergency within the vulnerability by Nicola Artusi, Emanuele Russo, Gianmaria Valeri, Marzia Tecchiolli, Franco Cominotto

“…Although  initially  observed  and  described  in  Japan,  this  psychiatric  condition  has  become  a  global  phenomenon  in  recent  years,  with  an  important  burden  on patients  and  their  families.  Hikikomori  syndrome  can  be  especially  dangerous  when  compounded  by  psychiatric  comorbidities  or  socioeconomic  vulnerabilities,  [2],  as  evidenced  by  an  alarming  increase  during  the  COVID-19  pandemic. …”
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Unveiling the diversity of macrobenthic crustaceans on sandy beaches of the eastern Mexican coast: new records and an updated checklist by María R. Muciño-Reyes, María R. Muciño-Reyes, Edlin Guerra-Castro, Edlin Guerra-Castro, Raúl E. Castillo-Cupul, Carlos E. Paz-Ríos, Nuno Simões, Nuno Simões, Nuno Simões

“…A total of 3,352 organisms were collected, representing 22 species from 17 genera, spanning 14 families, 7 suborders, 5 orders, and 2 superorders. …”
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Genome wide association studies on seven yield‐related traits of 183 rice varieties in Bangladesh by Nilanjan Roy, Acramul Haque Kabir, Nourin Zahan, Shahba Tasmiya Mouna, Sakshar Chakravarty, Atif Hasan Rahman, Md. Shamsuzzoha Bayzid

“…Our study also underscores the involvement of transposon gene families across these three traits. For leaf related traits, chromosome 10 was found to harbor regions that are significantly associated with leaf length and leaf width. …”
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