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281
Exosome in Crosstalk between Inflammation and Angiogenesis: A Potential Therapeutic Strategy for Stroke
Published 2022-01-01“…Exosomes are the heterogeneous population of extracellular vesicles which play critical roles in intercellular communication through transmitting various proteins and nucleic acids to nearby and distant recipient cells by body fluids and circulation. …”
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282
Exosomes, their sources, and possible uses in cancer therapy in the era of personalized medicine
Published 2024-12-01“…Exosomes, a primary type of extracellular vesicles, can transport diverse intracellular molecules to nearby or distant cells and organs, facilitating numerous biological functions. …”
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283
The Crosstalk between Ovarian Cancer Stem Cell Niche and the Tumor Microenvironment
Published 2017-01-01“…This interaction can be mediated by cytokines, growth factors, lipids, and/or extracellular vesicles released in the CSC niche. In this review, we will discuss how the interaction between ovarian CSCs and the tumor microenvironment can contribute to the maintenance of the CSC niche and consequently to tumor progression in ovarian cancer.…”
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284
Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo
Published 2025-01-01“…Notably, diffusible forms of NRP1 in the extracellular space have been reported, but their functional role is poorly understood. Methods Extracellular vesicles (EV) were isolated from conditioned media of diverse cancer cells. …”
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285
Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis
Published 2024-12-01“…Analyzing the nucleic acid content of liquid biopsy samples, which include Circulating Tumor Cells (CTCs), Circulating Tumor DNA (ctDNA), Circulating Cell-Free RNA (cfRNA), and tumor extracellular vesicles, provides a noninvasive method for cancer detection and monitoring. …”
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286
Single-cell sequencing in diabetic retinopathy: progress and prospects
Published 2025-01-01“…Additionally, single-cell sequencing is widely employed to analyze retinal organoids and single extracellular vesicles. Single-cell multi-omics sequencing integrates omics information, whereas stereo-sequencing analyzes gene expression and spatiotemporal data simultaneously. …”
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287
Nanomédicaments pour le traitement de maladies graves et recherches duales
Published 2024-11-01“…The potential of extracellular vesicles and exosomes as drug carriers is also explored. …”
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288
Exosome-Like Vesicles as New Mediators and Therapeutic Targets for Treating Insulin Resistance and β-Cell Mass Failure in Type 2 Diabetes Mellitus
Published 2019-01-01“…Exosome-like vesicles (ELVs), the smallest class of extracellular vesicles released from cells, function in cellular crosstalk and therefore profoundly affect physiologic responses and pathologic progression. …”
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289
Exosomes: new targets for understanding axon guidance in the developing central nervous system
Published 2025-01-01“…Axon guidance is a key event in neural circuit development that drives the correct targeting of axons to their targets through long distances and unique patterns. Exosomes, extracellular vesicles that are smaller than 100 nm, are secreted by most cell types in the brain. …”
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290
Diagnostic and Prognostic Significance of Exosomes and Their Components in Patients With Cancers
Published 2025-01-01“…ABSTRACT Background Cancer is the second leading cause of human mortality worldwide. Extracellular vesicles (EVs) from liquid biopsy samples are used in early cancer detection, characterization, and surveillance. …”
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291
Parkinson’s disease and exosomes: from pathogenesis to diagnosis and treatment
Published 2021-06-01“…Of great interest are exosomes, extracellular vesicles isolated from the cellular endosomal system. …”
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292
Noble Metal Nanoparticle‐Based Aptasensors: A Powerful Tool for Exosomal Detection
Published 2025-01-01“…In this review, the progress will summarized in exosomes as a biomarker for diseases and the recent advances in the use of noble metal nanoparticle/aptamer‐based sensors for analysis of exosomes and other extracellular vesicles.…”
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293
CAF-EVs carry lncRNA MAPKAPK5-AS1 into hepatocellular carcinoma cells and promote malignant cell proliferation
Published 2024-12-01“…This study explores the role of MAPKAPK5-AS1 carried by carcinoma-associated fibroblasts-derived extracellular vesicles (CAF-EVs) in HCC cell proliferation. …”
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294
Brain injury biomarkers and applications in neurological diseases
Published 2025-01-01“…In this review, we described biomarkers for neuronal cell body injury (neuron-specific enolase, ubiquitin C-terminal hydrolase-L1, αII-spectrin), axonal injury (neurofilament proteins, tau), astrocyte injury (S100β, glial fibrillary acidic protein), demyelination (myelin basic protein), autoantibodies, and other emerging biomarkers (extracellular vesicles, microRNAs). We aimed to summarize the applications of these biomarkers and their related interests and limits in the diagnosis and prognosis for neurological diseases, including traumatic brain injury, status epilepticus, stroke, Alzheimer’s disease, and infection. …”
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295
Mesenchymal stem cells derived exosomes: a new era in cardiac regeneration
Published 2025-01-01“…In recent years, stem cells have emerged as a promising tool for tissue regeneration, but challenges such as graft rejection and tumor formation have limited their clinical application. Exosomes, extracellular vesicles containing a diverse array of biomolecules, have garnered significant attention for their potential in regenerative medicine. …”
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296
Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche
Published 2016-01-01“…Stem cells, as well as most cells, release extracellular vesicles such as exosomes, which are nanovesicles able to target specific cell types and thus to modify their function by delivering proteins, lipids, and nucleic acids. …”
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297
Non-Invasive Biomarkers and Breath Tests for Diagnosis and Monitoring of Chronic Liver Diseases
Published 2024-12-01“…Emerging biomarkers such as extracellular vesicles and circulating microRNAs show promise in early detection and personalized monitoring. …”
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298
Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection
Published 2022-01-01“…Exosomes are nanoscale small extracellular vesicles abundant with protein cargo and can mediate immune response during infectious disease. …”
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299
<i>Akkermansia muciniphila</i>: A Potential Target for the Prevention of Diabetes
Published 2024-12-01“…Thus, <i>A. muciniphil</i> and its components, including the outer membrane protein Amuc_1100, <i>A. muciniphila</i>-derived extracellular vesicles (AmEVs), and the secreted proteins P9 and Amuc_1409, are systematically summarized with respect to mechanisms of action in diabetes mellitus. …”
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300
Selected Aspects in the Pathogenesis of Autoimmune Diseases
Published 2015-01-01“…Finally we describe the function and role of extracellular vesicles in particular autoimmune diseases. …”
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