Impact of Online Interactive Decision Tools on Women’s Decision-Making Regarding Breast Cancer Screening: Systematic Review and Meta-Analysis by Patricia Villain, Laura Downham, Alice Le Bonniec, Charlotte Bauquier, Olena Mandrik, Tom Nadarzynski, Lorie Donelle, Raúl Murillo, Eleni L Tolma, Sonali Johnson, Patricia Soler-Michel, Robert Smith

“…We conducted meta-analyses on the identified randomized controlled trials, which were assessed using the revised Cochrane Risk of Bias 2 (RoB 2) tool. We further explored intermediate and high heterogeneity between studies to enhance the validity of our results. …”
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Effect of bright light therapy combined with five-element music therapy on negative emotions and sleep quality of pregnant women (强光联合五音疗法对孕妇负面情绪及睡眠质量的影响)... by ZHANG Caixia (张彩霞), ZHANG Ping (张萍), CAI Donglin (蔡东林), AN Rongrong (安溶溶)

“…Objective To explore the effect of bright light therapy combined with five-element music therapy on negative emotions and sleep quality of pregnant women with depression. …”
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Effect of Ginkgolide B on Non-Alcoholic Fatty Liver Disease based on Notch Signaling Pathway by Hong YU, Junzi WU, Bo SONG, Jun LI

“…Objective:To explore the interventional effect of Ginkgolide B on non-alcoholic fatty liver disease (NAFLD) based on the Notch signal pathway, and provide basis for Ginkgolide B in treating NAFLD.Methods:A total of 72 SD rats were divided into the normal group and the experiment group according to the random number method, with 12 cases in the normal group and 60 cases in the experiment group. …”
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A topographically controlled tipping point for complete Greenland ice sheet melt by M. Petrini, M. Petrini, M. D. W. Scherrenberg, L. Muntjewerf, L. Muntjewerf, M. Vizcaino, R. Sellevold, G. R. Leguy, W. H. Lipscomb, H. Goelzer

“…Previous work on the magnitude and nature of a threshold for GrIS complete melt remains controversial. Here, we explore a potential SMB threshold for complete melt of the GrIS; the impact and interplay of surface melt and glacial isostatic adjustment (GIA) in determining this threshold; and whether the GrIS exhibits characteristics commonly associated with tipping points, such as sensitivity to external forcing. …”
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Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis by Michele Maremmani, Ramin Ebrahimi, Marco Centola, Felice Achilli, Valentina Capone, Eduardo Bossone, Christian Templin, Davide Di Vece

“…This meta-analysis aimed to assess the association of SGLT2 inhibitors with all-cause mortality in post-MI patients and to explore key moderators influencing this benefit. Methods PubMed, Embase, and Scopus were searched for randomized controlled trials (RTCs) and propensity score-matched (PSM) observational studies assessing SGLT2 inhibitors' impact on post-MI mortality. …”
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Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies by Francesco Di Pierro, Francesco Di Pierro, Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova

“…Quercetin, a naturally occurring flavonoid, has shown potential as a hypouricemic agent through XO inhibition.ObjectiveThis study aims to evaluate the potential hypouricemic effect of Quercetin Phytosome™ (QP) supplementation across three cohort studies involving healthy adults with various metabolic health profiles, exploring its potential as a safe, effective intervention for hyperuricemia.MethodsClinical data collected in various clinics in Italy between September 2021 and April 2024 under real-life clinical settings from three distinct cohort studies, were analyzed. …”
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Effects of Electroacupuncture Preconditioning at Baihui and Zusanli Acupoints on the Expression of Inflammatory Factors in Brain and Intestines of Rats with Cerebral Ischemia/Reper... by ZHANG Jiyao, TANG Qiang, ZHU Luwen

“…ObjectiveTo observe the effects of electroacupuncture preconditioning on the expression of interleukin-17A（IL-17A）and IL-10 in the brain and intestine of rats with cerebral ischemia/reperfusion and to explore the brain-gut protective effect of electroacupuncture preconditioning.MethodsA total of 36 male Sprague-Dawley rats were randomly divided into the sham group (S-con group), the model group (M-con group), and the electroacupuncture preconditioning group (EP group) ,with 12 cases in each group. …”
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A socio-ecological model of the management of leprosy reactions in Indonesia and India using the experiences of affected individuals, family members and healthcare providers by Annisa Ika Putri, Ruth M. H. Peters, Kevin De Sabbata, Brittney S. Mengistu, Regitta I. Agusni, Medhi Denisa Alinda, Joydeepa Darlong, M. Yulianto Listiawan, Cita R. S. Prakoeswa, Stephen L. Walker, Marjolein B. M. Zweekhorst

“…Barriers to accessing care and services are a major cause of suboptimal care for people with leprosy. This study aims to explore the barriers to and facilitators of high-quality care and management of LR in two leprosy-endemic countries with different health care models – Indonesia and India – and identify areas for improvement. …”
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Real-world experience with nucleos(t)ide analogue therapy and patient survival rates in chronic viral hepatitis B treatment centers in Eritrea by Michael Berhe Solomon, Ghirmay Ghebrekidan Ghebremeskel, Oliver Okoth Achila, Aron Rezene Mebrahtu, Mohammed Elfatih Hamida, Araia Berhane Mesfin

“…Relevant parametric and nonparametric statistics were employed to explore treatment outcomes and to evaluate differences between groups. …”
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Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…Objective: The aim of the present study was to explore the perceived acceptability and implementation challenges of BPG treatment for RHD, from the perspective of healthcare providers (HCPs). …”
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Biological embodiment of educational attainment and future risk of breast cancer: findings from a French prospective cohort by Cyrille Delpierre, Raphaële Castagné, Eloïse Berger, Gianluca Severi, Marie-Christine Boutron-Ruault, Laura Baglietto, Laure Dossus, Amandine Gelot, Richard Dudouet

“…We focused on biomarkers from several physiological systems examined individually, and jointly through a biological health score (BHS).Design Prospective cohort study.Setting This study, based on a subsample of the French E3N cohort, included women with biological data from four nested case–control studies.Participants The study included 3048 postmenopausal women (17% BC).Main outcome measures We first evaluated the association between educational attainment and each biomarker, separately (N=11) and by combining them into a BHS, indicative of an augmented biological health hazard when elevated. Finally, we explored the relationships between the socially patterned biomarkers and BHS, and risk of incident BC.Results Women with higher educational attainment exhibited a lower BHS in comparison to those with lower educational attainment (βhigh education=−0.21 (95% CI −0.42; 0.01), model 2). …”
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Prevalence and molecular characterization of human bocavirus-1 in children and adults with influenza-like illness from Kunming, Southwest China by Yanhong Sun, Lili Jiang, Yaoyao Chen, Zhaosheng Liu, Meiling Zhang, Xiaonan Zhao, Xiaoyu Han, Lifen Zhang, Xiaoqing Fu, Jienan Zhou

“…Further studies are necessary to explore the clinical implications of HBoV-1 infection and its role in respiratory illnesses.IMPORTANCEViral respiratory infections are a leading cause of morbidity- and mortality-associated influenza-like illness (ILI) cases. …”
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Impact of protein intake from a caloric-restricted diet on liver lipid metabolism in overweight and obese rats of different sexes by Ying Tian, Jiawei Gong, Zhiyan He, Suwen Peng, Yuping Huan, Hongpeng Cao

“…The purpose of this study is to explore the effects and mechanisms of different protein intakes within a calorie-restricted diet on liver lipid metabolism, and to investigate whether these effects exhibit gender differences. …”
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Machine learning for predicting neoadjuvant chemotherapy effectiveness using ultrasound radiomics features and routine clinical data of patients with breast cancer by Pu Zhou, Pu Zhou, Hongyan Qian, Pengfei Zhu, Jiangyuan Ben, Jiangyuan Ben, Guifang Chen, Qiuyi Chen, Lingli Chen, Jia Chen, Ying He, Ying He

“…BackgroundThis study explores the clinical value of a machine learning (ML) model based on ultrasound radiomics features of primary foci, combined with clinicopathologic factors to predict the pathological complete response (pCR) of neoadjuvant chemotherapy (NAC) for patients with breast cancer (BC).MethodWe retrospectively analyzed ultrasound images and clinical information from 231 participants with BC who received NAC. …”
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Derivation and validation of a prediction model for inadequate bowel preparation in Chinese outpatients by Huifang Yin, Yan Wang, Hangfang Wang, Tian Li, Xiangxiang Xu, Fengyu Li, Lihua Huang

“…The main objective of this study was to explore the specific factors that affect the quality of bowel preparation, with the goal of deriving and validating a predictive model for inadequate bowel preparation in Chinese outpatients. …”
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Effect of Scalp-acupuncture Treatment on Language Reorganization in Poststroke Aphasia：A Functional Near-Infrared Spectroscopy by LIN Bingbing, NI Jinglei, XIONG Xiao, HUANG Yunshi, HUANG Jia

“…Objective Based on functional near infrared spectroscopy （fNIRS），to explore the scalp targeting language function and its neurological mechanism of action in patients with post-stroke aphasia （PSA）. …”
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L-glutaminase synthesis by Klebsiella pneumoniae (AS KP 23) isolated from clinical strain, and its efficacy against human hepatocellular and breast cancer cell lines by Lina J. Abdel-Hafez, Eman Y. T. Elariny, Asmaa E. Ibrahim, Mahmoud E. F. Abdel-Haliem

“…Recently, the role of glutamine metabolism in cancer has been explored in many studies. Therefore, it provides a scientific relationship for targeting glutamine metabolism for cancer treatment. …”
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GPR87 promotes invasion and migration through the RHO/ROCK pathway in non-small cell lung cancer by LIU Chenxi, HAN Lin, YANG Yi, ZHOU Han, LIU Yayun, SHENG Deqiao

“…Objective·To explore the role and molecular mechanism of GPR87 in regulating the invasion and migration of non-small cell lung cancer (NSCLC).Methods·Bioinformatics methods, including GEO, UALCAN, KM Plotter and other public database analysis platforms, were used to screen candidate genes related to NSCLC invasion and predict their clinical relevance to NSCLC. …”
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Characteristics and prognostic factors of chronic kidney disease patients with Pneumocystis jirovecii pneumonia by Liu Xiao-hua, Wu Jing-jing, Zeng Ming, Ge Yi-fei, Zhang Bo, Wu Bu-yun, Mao Hui-juan

“…ObjectiveTo explore the clinical and prognostic characteristics of chronic kidney disease （CKD） patients with Pneumocystis jirovecii pneumonia （PJP）， thus facilitating the diagnosis and treatment of Pneumocystis jirovecii infections.MethodsWe retrospectively analyzed the clinical date of 22 CKD patients with PJP who were hospitalized in the First Affiliated Hospital with Nanjing Medical University and diagnosed by metagenomic next-generation sequencing （mNGS） from October 1， 2019 to October 31， 2023. …”
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La nécropole de Vannes/Darioritum : données inédites sur les pratiques funéraires armoricaines dans un secteur occupé du ier au ive s. apr. J.-C. by Annaïg Le Martret, Marie Grall, Vanessa Brunet

“…The necropolis of Vannes/Darioritum (Morbihan, France) has been known since the 19th century, but it was only really explored in 2015, during a preventive excavation. As is usually the case, it is located beside a road and close to an entrance to the town. …”
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