A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis by Ruidong Mo, Zhenglan Zhang, Yanmei Zhou, Yue Wang, Pengbo Yin, Chenxi Zhang, Haoshuang Fu, Cong Qian, Xiaogang Xiang, Rongkun Yin, Qing Xie

“…The dynamics of serum apoAI levels were also explored in 37 HBV-ACLF patients. Results In the cohort, the negatively correlation was found between the Model for End-Stage Liver Disease (MELD) score and serum apoAI levels (r = -0.7946, P < 0.001). …”
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LncRNA PTS-1 Protects Against Osteoarthritis Through the miR-8085/E2F2 Axis by Ma C, Chen Q, Wei YF, Chen SW, Liu H, Xin F, Ren YX

“…This study focuses on lncRNA PTS-1, a novel lncRNA, to explore its function and regulatory mechanisms in OA progression.Methods: The expression profile of lncRNAs was assessed using RNA sequencing and qRT-PCR. …”
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Effects of Bedaquiline on Antimicrobial Activity and Cytokine Secretion of Macrophages Infected with Multidrug-Resistant Mycobacterium tuberculosis Strains by Xia-Li Lyu, Ting-Ting Lin, Jing-Tao Gao, Hong-Yan Jia, Chuan-Zhi Zhu, Zi-Hui Li, Jing Dong, Qi Sun, Wei Shu, Sai-Sai Wang, Li-Ping Pan, Hai-Rong Huang, Zong-De Zhang, Qi Li

“…Here, Bdq bactericidal activities against MDR-MTBs and related cellular immune mechanisms were explored. Methods. Macrophages infected with MDR-MTBs or H37Rv received Bdq treatments (4 h/8 h/24 h/48 h) at 1 × the minimum inhibitory concentration (1 × MIC), 10 × MIC and 20 × MIC. …”
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Finite element investigation for improving chest wall reconstruction process using ceramic and polymeric implants by Yomna H. Shash

“…This research aims to explore alternatives to metallic implants in order to overcome their drawbacks and enhance the performance of chest wall reconstruction using the finite element method. …”
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Adaptación y dimensionalidad de la escala DOCS en el contexto organizacional costarricense: aplicación de la entrevista cognitiva y el análisis factorial confirmatorio/ Adaptation... by Tómas Vargas-Halabí, Ronald Mora-Esquivel

“…Eight types of confirmatory factor analyses were performed using EQS 6.3 software in order to explore the dimensionality of the adapted scale and to debug the final version. …”
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Similar Survival Between Non-Western Immigrant Patients and Danish-Born Patients with Lymphoma: A Danish Population-Based Study by Simonsen MR, Maksten EF, Jakobsen LH, Severinsen MT, Dann EJ, Frederiksen H, Niemann CU, Jørgensen JM, Clausen MR, Starklint J, Johnsen SP, El-Galaly TC, Baech J

“…Furthermore, differences in clinical and socioeconomic variables were compared, and mediators of OS differences were explored to explain possible outcome differences.Patients and Methods: The study included a total of 540 non-Western patients and 16,294 Danish-born patients diagnosed with lymphoma in the period 2000– 2020. …”
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Mechanism of warmed malate ringer’s solution in fluid resuscitation in improving the lethal triad of severe trauma by WU Yinyu, SHE Han, SHE Han, DU Yunxia, DU Yunxia

“… ‍Objective‍　‍To explore the role and mechanism of warm malate ringer’s solution (MR) in resuscitation of the lethal triad caused by severe trauma. …”
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Time-frequency characterization of acoustic emission signals from bending damage of corroded reinforced concrete beams in high- temperature saline environment by Dazhong Zhang, Shiyi Zhang, SM Chayan, Yingfang Fan, Surendra P. Shah, Junjie Zheng

“…To analyze the crack development characteristics of corroded reinforced concrete (RC) beams in high-temperature saline environment flexural failure, and to explore the degradation laws of beams' flexural performance after high-temperature corrosion, as well as the time-frequency characteristics of the acoustic emission signals during flexural failure; employing electrochemical acceleration corrosion and four-point bending tests, combined with acoustic emission technology, establishes a connection between the flexural failure process of concrete beams under three conditions: unrusted (RC-1), rusted at room temperature (CRC-1), and rusted at high temperature (GRC-1). …”
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Influence of mental workload on professional identity of nursing students who were born between 1995 and 1999 (“95后”护生工作心理负荷对职业认同的影响) by LU Sheng (陆晟), WANG Zhenmeng (王振猛), SHENG Yuehong (盛月红)

“…Objective To explore the influence of mental workload on professional identity of nursing students who were born between 1995 and 1999, in order to provide a basis for enhancing their sense of professional identity and provide advice to healthcare managers for decision-making. …”
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USP22 inhibits microglial M1 polarization by regulating the PU.1/NLRP3 inflammasome pathway by Ming-chen Yu, Xiao-lin Li, Ming-liang Ning, Zhen-zhong Yan, Wan-tao Yu

“…Objective: This study aimed to investigate the effect of Ubiquitin-Specific Peptidase 22 (USP22) on the inflammatory response mediated by BV-2 mouse microglia and explore the role of the PU box binding protein 1 (PU.1)/NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome in the USP22-induced polarization of BV-2 cells. …”
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Testing a Web-Based Interactive Comic Tool to Decrease Obesity Risk Among Racial and Ethnic Minority Preadolescents: Randomized Controlled Trial by May May Leung, Katrina F Mateo, Marlo Dublin, Laura Harrison, Sandra Verdaguer, Katarzyna Wyka

“…Its preliminary effectiveness on diet-related psychosocial variables and behaviors was also explored. MethodsA total of 89 Black or African American and Hispanic preadolescents with a mean age of 10.4 (SD 1.0) years from New York City participated in a pilot 2-group randomized study, comprising a 6-week intervention and a 3-month follow-up (T4) period. …”
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Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia by Zirong Li, Yi Shu, Deguo Liu, Sheng Xie, Liangbo Xian, Jiaqi Luo, Xiuwen Huang, Haixing Jiang

“…The abnormal mitochondrial autophagy signaling caused by the putative kinase 1/Parkin E3 ubiquitin protein ligase (Pink1/Parkin) signaling pathway directly affects the normal secretion of melatonin by the pineal gland, which may explain the pathogenesis of depression combined with insomnia. This study aims to explore the depression-like behavior, sleep changes, central oxidative stress response, pineal mitochondrial autophagy damage, melatonin secretion, histopathological changes of the pineal gland, and the expression of Pink1/Parkin signaling-related factors in CUMS+SD rats. …”
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Rapid weight loss and combat athletes: a study on psychological resilience and mechanical hyperalgesia by Esin Çağla Çağlar, Levent Ceylan, Sermin Ağralı Ermiş, Furkan Çamiçi, Murat Eliöz, Recep Nur Uzun, Güner Çiçek, Muhammet Kusan, Mustafa Tolga Bayraktar, Fatma Neşe Şahin, Hamza Küçük

“…Future research should explore interventions to optimize resilience and manage pain during RWL periods, focusing on individualized support strategies for athletes. …”
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Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide by Xie Y, Zhu M, Bao H, Chen K, Wang S, Dai J, Chen H, Li H, Song Q, Wang X, Yu L, Pei J

“…Finally, the acute toxicity of Rg3-Lip-OXA/CaO2 was investigated in ICR mice to explore its safety.Results: The XRD and XPS analyses confirmed the successful synthesis of CaO2 nanoparticles. …”
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Association between Corneal Stiffness Parameter at the First Applanation and Keratoconus Severity by Kaili Yang, Liyan Xu, Qi Fan, Shengwei Ren

“…The study aimed to evaluate the character of corneal stiffness parameter at the first applanation (SP-A1) in normal and keratoconus eyes and explore the association between SP-A1 and keratoconus severity indicators. …”
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Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study by Yulin Hswen, Qiuyuan Qin, Pressley Smith, Alison Swierczynski, Stuart Bauer, Erika Ladson, Amanda Leigh Garrett, Catherine A Brownstein

“…This research confirms that individuals with actively engage with health forums like Inspire to seek information, share their experiences, and explore different treatment options. As remains a complex syndrome, this study highlights the value of patient-led discussions in informing treatment decisions. …”
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Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers by Liming Liang, Xinyu Wang, Yue Zhu, Xu Xia, Runfeng Shi, Huilin Cao, Meixin He, Yuyu Wang, Caizhen You

“…In view of these facts, the current situation, status, problems and development trends of vaccine research and application were explored through bibliometric analysis of highly cited papers in the vaccine field within the time frame of 2014–2024, and the countries, institutions, authors, funding agencies and other relevant information that contributed most to vaccine research and application were summarised.Design Bibliometric analysis through data analysis and visual mapping.Data sources Scientific articles.Data extraction and synthesis ‘Vaccine’ and ‘vaccines’ were used in the WoS database to retrieve the publications and to adequately collect the data; Microsoft Excel was used for data analysis; and VOSviewer was used for visual description of data. …”
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L’apport de la géomatique à la connaissance de la partie terminale de l’aqueduc du Gier à Lyon by Éric Leroy

“…In total, 23 sites were explored in the course of this study. The available documentation was compiled and processed within the municipal archaeology department’s Geographic Information System (GIS), known as Alyas (Lyon Archaeology and Spatial Analysis).The aqueduct generally follows a straight line in the part of the route that interests us, but the topography also demands more sinuous underground sections. …”
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Correlation between social support, self-efficacy and quality of life in primary trigeminal neuralgia patients (原发性三叉神经痛患者社会支持、自我效能感与生活质量的相关性研究)... by SUN Xiuxiu (孙秀秀), JIA Jianhua (贾建华), LI Yeyuan (李业园)

“…Objective To explore the correlation between social support, self-efficacy and quality of life of patients with primary trigeminal neuralgia, and to provide reference basis for optimizing the quality of life. …”
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Transcriptomic Analysis of Menstrual Blood-Derived Stem Cells Transplantation Combined with Exercise Training in Promoting Spinal Cord Injury Recovery in Rats by QI Longju, CHEN Shiyuan, LIAO Zehua, SHI Yuanhu, SUN Yuyu, WANG Qinghua

“…ObjectiveTo explore the potential therapeutic targets and molecular mechanisms of menstrual blood-derived stem cells (MenSCs) transplantation combined with exercise training in promoting recovery in rats with spinal cord injury (SCI) through transcriptome sequencing analysis.MethodsFemale SD rats aged two months were selected and a SCI model was established by a hemisection at the tenth thoracic vertebra (T10). …”
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