Detecting respiratory impairment in newly diagnosed rheumatoid arthritis by MRC dyspnoea scale and microfibrillar-associated protein 4 by Bjørk K. Sofiudottir, Sören Möller, Robin Christensen, Stefan Harders, Grith L. Sørensen, Jesper Blegvad, Mette Herly, Dzenan Masic, Grazina Urbonaviciene, Frank Andersen, Christin Isaksen, Brian Bridal Løgstrup, Charlotte Hyldgaard, Torkell Ellingsen

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Network Pharmacology, Molecular Docking, and Molecular Dynamics Analysis of Honokiol against Triple-negative Breast Cancer by Hassan H. Alhassan

“…Aims: This study aimed to explore the molecular mechanisms underlying honokiol’s anticancer effects against TNBC through a multidisciplinary approach integrating network pharmacology, molecular docking, and molecular dynamics analysis. …”
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Designing a Conceptual model for Evaluating the Performance of Software Developers in Fintech Organizations by Hassan Javadi, Fereshteh Amin

“…Although various studies have explored certain aspects of performance criteria, no comprehensive and integrated study has been undertaken in this regard. …”
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Nomogram based on the neutrophil-to-lymphocyte ratio and MR diffusion quantitative parameters for predicting Ki67 expression in hepatocellular carcinoma from a prospective study by Yu-chen Wei, Liang yun, Yan-ling Liang, Robert Grimm, Chongze Yang, Yuan-fang Tao, Sheng-chen Jiang, Jin-yuan Liao

“…Abstract This study aimed to establish and validate a multiparameter prediction model for Ki67 expression in hepatocellular carcinoma (HCC) patients while also exploring its potential to predict the one-year recurrence risk. …”
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Betulinic Acid Inhibits the Metastasis of Colon Cancer Cells through Regulating TGF-β/Smad Signaling Pathway by Xiaoying LIN, Aling SHEN, Meizhu WU, Ying CHENG, Xiaoping CHEN, Huixin LIU, Liya LIU, Zhiqing SHEN, Xiangyan WU, Nanhui XU, Jianfeng CHU, Youqin CHEN, Jun PENG

“…Objective:To explore the effect of betulinic acid (BA) on the growth and metastasis of colon cancer cell line HCT116 and the underlying possible mechanism.Methods:HCT116 cells were cultured with McCoy's 5A medium containing 10%fetal bovine serum and 1%penicillin/streptomycin mixed solution in a 37℃,5%CO₂incubator. …”
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Use of Go-Beyond as a Self-Directed Internet-Based Program Supporting Veterans’ Transition to Civilian Life: Preliminary Usability Study by Karolina Katarzyna Alichniewicz, Sarah Hampton, Madeline Romaniuk, Darcy Bennett, Camila Guindalini

“…Future research should explore predictors of engagement, the addition of peer or facilitator support, and the use of outcome measures for effectiveness assessment.…”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Additionally, we analyzed single-cell RNA-seq (scRNA-seq) data from AD patients’ brain tissue and peripheral blood, combined with scRNA-seq data from experimental autoimmune encephalomyelitis (EAE) mouse brain tissue. This enabled us to explore AD-related molecular mechanisms from a cell-type-specific perspective. …”
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Clinicopathological analysis of adrenal intravascular large B-cell lymphoma by LIN Jiaxin, WEI Ran, SHUI Ruohong, LU Hongfen, LI Xiaoqiu, YU Baohua

“…It is of great importance to accumulate more cases and further understand the clinicopathological and molecular genetic characteristics of this rare disease, which might not only help with early diagnosis, timely treatment and improvement of prognosis, but also provide a theoretical basis for further understanding the pathogenesis and development of the disease and exploring therapeutic targets.…”
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Athletic Shoulder Test Differences Exist Bilaterally in Healthy Pitchers by Aaron Trunt, Brandon T. Fisher, Lisa N. MacFadden

“…However, the test has not been explored widely in throwing athletes who are known to have significant musculoskeletal adaptations to the throwing shoulder…”
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Association of social frailty, sarcopenia, and oral frailty with depressive symptoms in Chinese older adults: a cross-sectional study by Yuanhao Sun, Huan Liu, Xiangdong Li, Lin Zhang, Wenwen Xu, Hairong liu, Ting Yuan

“…Future research should further explore the two-way relationship between these factors and depressive symptoms and assess the effectiveness of different interventions. …”
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Construction and characterization of chimeric FcγR T cells for universal T cell therapy by Juanjuan Zhao, Manling Chen, Xudong Li, Zhaoqi Chen, Wei Li, Rongqun Guo, Min Wang, Zhongxing Jiang, Yongping Song, Jianxiang Wang, Delong Liu

“…Abstract Background Several approaches are being explored for engineering off-the-shelf chimeric antigen receptor (CAR) T cells. …”
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Automatic detection and multi-component segmentation of brain metastases in longitudinal MRI by Vincent Andrearczyk, Luis Schiappacasse, Daniel Abler, Marek Wodzinski, Andreas Hottinger, Matthieu Raccaud, Jean Bourhis, John O. Prior, Vincent Dunet, Adrien Depeurnge

“…Automatic detection and segmentation can assist radiologists in these tasks. This work explores the automated detection and segmentation of brain metastases (BMs) in longitudinal MRIs. …”
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Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Mult... by Tan Y, Jiang H, Tian X, Ma F, Wang J, Zhang P, Xu B, Fan Y, Zhao W

“…Yujing Tan,1,* Hanfang Jiang,2,* Xinzhu Tian,1,* Fei Ma,1 Jiayu Wang,1 Pin Zhang,1 Binghe Xu,1 Ying Fan,1 Weihong Zhao3 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, People’s Republic of China; 3Department of Medical Oncology, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Fan; Weihong Zhao, Email fanying@cicams.ac.cn; zhaowh0818@163.comPurpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC).Methods: NOLUS has previously been established as an algorithm: NOLUS (0– 100) = − 0.45 × ER(%) − 0.28 × PR(%) + 0.27 × Ki67(%) + 73. …”
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Effects of virtual reality technology on early mobility in critically ill adult patients: a systematic review and meta-analysis by Yansha He, Yansha He, Qin Yang, Xiaoxia Dai, Tian Chen, Huan Wu, Kunjie Li, Shiqiong Zhu, Yanlin Liu, Hua Lei

“…ObjectiveThe study aimed to explore the effects of virtual reality (VR) technology on motor function rehabilitation in critically ill patients.MethodsAdhering to the PRISMA systematic evaluation method for developing the literature ranking criteria and search strategy, the following databases were systematically searched: PubMed, Embase, Web of Science, the Cochrane Library, CNKI, Wanfang Data, Chinese Medical Journal Full-Text Database, and SINOMED. …”
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Harmony with Nature: A Literature Review of Islamic and Perennial Values in Cikondang Indigenous Traditions by Didi Supandi, Che Zarrina binti Sa'ari, Abdillah Abdillah, Naan Naan

“…Therefore, this research aims to explore and analyze existing literature to understand how Islamic and perennial values are reflected in the traditions of the Cikondang community and how these values can contribute to efforts to maintain harmony between humans and nature. …”
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Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study by Andong Guo, Pengcheng Chen, Jishuang Cao, Chenrui Wu, Sentai Ding

“…Purpose: This study aimed to explore the association and causal links between sex steroid hormones and the anti-aging protein α-Klotho, extending to investigate the mediation effects of potential mediators. …”
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Quality of life among residents of informal urban settlements during the COVID-19 pandemic in Salvador, Brazil by Albert I Ko, Federico Costa, Hammed Mogaji, Nivison Nery, Hernan D Argibay, Jaqueline S Cruz, Ianei O Carneiro, Ricardo Lustosa, Mike Begon, Hussein Khalil

“…We describe the HRQOL of residents, explored participants’ perception about the pandemic, and the relationship between sociodemographic, economic and employment data on physical and mental health scores using both χ2 statistics and separate mixed-effects regression models.Results Most participants were female (58.9%), aged 18–45 years (45%), with nearly half (49.7%) employed before pandemic, of whom 38.8% lost jobs during the pandemic. …”
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Trends, challenges and solutions of digital information security in Central and Eastern Europe by Serhii Lubenets, Igor Harchenko, Tetiana Shediakova

“…Task: to process and analyze current reporting related to the current state of international digital information security in the CEE region; to explore the key trends, challenges, problems and industry specificities of digital information security in CEE; analyze approaches to assessing the current state of information security of international organizations in the CEE region and directions for its improvement. …”
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Assessment of Visual Quality in Eyes with Forme Fruste Keratoconus and Mild and Moderate Keratoconus Based on Optical Quality Analysis System II Parameters by Zhonghao Ren, Liyan Xu, Qi Fan, Kaili Yang, Shengwei Ren, Dongqing Zhao

“…The study aimed to evaluate the visual quality of forme fruste keratoconus (FFK) and mild and moderate keratoconus by using an optical quality analysis system II (OQAS-II) and to explore the correlation between optical quality parameters and the disease progression. …”
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Resistance exercise training improves disuse-induced skeletal muscle atrophy in humans: a meta-analysis of randomized controlled trials by Xian Guo, Yanbing Zhou, Xinxin Li, Jinhao Mu

“…Further research is needed to explore the effects of RET in more diverse populations and under various disuse conditions. …”
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