Genetic diversity and population structure studies of West African sweetpotato [Ipomoea batatas (L.) Lam] collection using DArTseq. by Issa Zakari Mahaman Mourtala, Arnaud Comlan Gouda, Dan-Jimo Baina, Nwankwo Innocent Ifeanyi Maxwell, Charlotte O A Adje, Moussa Baragé, Oselebe Ogba Happiness

“…Niger, Nigeria, and Benin have a huge diversity of sweetpotato accessions whose potential has not fully been explored to date. Diversity Arrays Technology (DArTseq), a Genotyping by Sequencing (GBS) method, has been developed and enables genotyping with high-density single nucleotide polymorphisms (SNPs) in different crop species. …”
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An Update of the Appropriate Treatment Strategies in Anaplastic Thyroid Cancer: A Population-Based Study of 735 Patients by Nai-si Huang, Xiao Shi, Bo-wen Lei, Wen-jun Wei, Zhong-wu Lu, Peng-cheng Yu, Yu Wang, Qing-hai Ji, Yu-long Wang

“…The aim of the current study is to explore whether aggressive treatment is beneficial, especially the appropriate extent of surgery in ATC. …”
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Descemet Endothelial Thickness Comparison Trial 1 (DETECT 1): outcome masked, placebo-controlled trial comparing two types of corneal transplant surgeries and effect of rho kinase... by Thomas M Lietman, Jennifer Rose-Nussbaumer, Bennie H Jeng, Benjamin F Arnold, Winston Chamberlain, Charles C Lin, Jennifer Y Li, William Gensheimer, Jameson Clover, Nicole Varnado, Sarah Abdelrahman

“…The results of this trial will contribute to optimising corneal transplantation techniques and improving long-term graft survival, while also exploring the cost-effectiveness of these interventions. …”
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Correlations of Cancer-Related Fatigue with Clinicopathological Features and Quality of Life in Gastric Cancer by Dong Liu, A-Dong Xia, Yue-Long Xing, Kai Zhang, Dan Chen

“…Objective. To explore the correlations of cancer-related fatigue (CRF) with clinicopathological features and quality of life in gastric cancer. …”
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A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study by Tanja Louise Ibsen, Ekaterina Zotcheva, Sverre Bergh, Debby Gerritsen, Gill Livingston, Hilde Lurås, Svenn-Erik Mamelund, Anne Marie Mork Rokstad, Bjørn Heine Strand, Richard C. Oude Voshaar, Geir Selbæk

“…Aim The primary aim was to examine changes in the prescription of analgesics (opioids and other analgesics) and psychotropics (anxiolytics/sedatives, antidepressants, and antipsychotics) in Norwegian home-dwelling older adults before, during, and up to 2 years after the COVID-19 lockdown, with a particular focus on dementia status. Secondarily, we explored individual characteristics associated with changes in medication prescriptions. …”
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Aspergillus fumigatus Influences Gasdermin-D-Dependent Pyroptosis of the Lung via Regulating Toll-Like Receptor 2-Mediated Regulatory T Cell Differentiation by Wei Yan, Yi-si Zhao, Ke Xie, Yu Xing, Fang Xu

“…The aim of this study was to explore whether A. fumigatus influences Gasdermin-D-dependent pyroptosis of the lung by regulating Toll-like receptor 2-mediated regulatory T cell differentiation. …”
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Editorial by Teddy Surya Gunawan

“…This issue reflects a commitment to addressing critical challenges, exploring innovative solutions, and advancing sustainable practices across various disciplines. …”
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Impact of Self-Management Clustered Care on Psychological and Birth Outcomes in Gestational Diabetes by Tang S, Wang S, Wu J, Hu S, Lu T, Zhu M, Li J, Xue F

“…SMB-CPCM shows a good prospect in the management of gestational diabetes and is worth promoting. Future research can explore the impact of SMB-CPCM on long-term health outcomes of pregnant women with diabetes, so as to comprehensively evaluate its clinical value.Keywords: clustered pregnancy care model, gestational diabetes, self-management ability, delivery outcomes, psychological state…”
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Association between the composite dietary antioxidant index and non-alcoholic fatty liver disease: evidence from National Health and Nutrition Examination Survey 2005–2016 by Yidian Fu, Yidian Fu, Chao Jiang, Zonglin Li, Xiangyun Shi, Peiyuan Lv, Peiyuan Lv, Jingbo Zhang

“…This association highlights the potential for dietary interventions to reduce NAFLD incidence and underscores the need for future research, including clinical trials and mechanistic studies, to further explore the role of dietary antioxidants in NAFLD prevention and management.…”
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Effect of High Frequency Repetitive Transcranial Magnetic Stimulation on Postoperative Cognitive Dysfunction in Elderly Mice Based on BDNF/TrkB Signaling Pathway by LI Min, YANG Xiao, REN Lulu, WU Tingmei, ZHANG Hong

“…On the third day after operation，the locomotor activity of mice was evaluated by open field test （percentage of stay time in the central area，total distance and average speed of movement）; On the fourth day after operation，the cognitive function of mice was evaluated by Y-maze test （the percentage of times to enter the new arm，the percentage of time to stay in the new arm，and the total distance to move the new arm）; After the Y-maze test，the protein expression levels of brain-derived neurotrophic factor （BDNF），tropomyosin related kinase B （TrkB） and nerve growth factor （NGF） in mice hippocampus were detected by immunoblotting.Results（1） Exercise capacity：there was no significant difference in the percentage of time spent in the central area of the open field，total distance and average speed among the three groups （<italic>P</italic>&gt;0. 05）. （2） Cognitive function：there was no significant difference among the three groups in the percentage of times of exploring new forearm （<italic>P</italic>&gt;0. 05）; Compared with the control group，the percentage of stay time in the new arm and the total distance of new arm movement in the operation group were significantly reduced，and the differences were statistically significant （<italic>P</italic>&lt;0. 05）. …”
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Organotin(IV) trifluoromethanesulfonate chemistry: isolation and characterization of novel 1,10-phenanthroline-based derivatives by Cattey, Hélène, Plasseraud, Laurent

“…The reactivity of 1 toward 2,9-dimethyl-1,10-phenanthroline was also explored (dmphen), leading to the detection of characteristic fingerprints of distannoxanes 2 and 4 by 119Sn{119H} NMR, and to the crystallization of phenanthrolinium triflate salts, which were characterized by X-ray diffraction analysis as dmphenHOTf and dmphenHOTf·dmphen.…”
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Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and meta-analysis by Robina Tasleem, Saleh Ali Alqahtani, Naif Abogazalah, Hussain Almubarak, Ammara Riaz, Sarosh Sher Ali, Zeeshan Allana

“…However, cost effectiveness, feasibility, durability, and long-term effects of microinvasive techniques need to be explored further.…”
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Effects of Functional Electrical Stimulation Based on Walking Pattern with Different Treatment Time on Lower Limb Function in Stroke Patients：A Randomized Controlled Study by XUE Jingjing, KONG Huimin, LIAO Meixin, XUE Yunlian, XIAO Lingjun

“…ObjectiveFocusing on the intelligent and multi-channel functional electrical stimulation (FES) based on normal walking patterns, we explored the correlation between therapeutic effect and stimulating time for improving lower extremity motor function of stroke patients, to provide evidence for further clinical applications of FES based on walking patterns.MethodsThe Minimize software was used to divided 18 stroke patients randomly into a group treated with 60 min FES in walking pattern (9 patients, 60 min-stimulation group), and the rest were treated with 30 min FES in walking pattern (9 patients, 30 min-stimulation group). …”
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Barriers and facilitators to maternal healthcare in East Africa: a systematic review and qualitative synthesis of perspectives from women, their families, healthcare providers, and... by Manaye Yihune Teshale, Agegnehu Bante, Abebe Gedefaw Belete, Rik Crutzen, Mark Spigt, Sarah E. Stutterheim

“…We systematically reviewed qualitative literature on maternal healthcare in East Africa, synthesizing insights from multiple perspectives and exploring barriers and facilitators across socioecological levels. …”
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Impact of the Mediterranean Diet on Patients With Psoriasis: Protocol for a Randomized Controlled Trial by Javier Perez-Bootello, Emilio Berna-Rico, Carlota Abbad-Jaime de Aragon, Ruth Cova-Martin, Leticia Goni, Asuncion Ballester-Martinez, Pedro Jaen-Olasolo, Nehal Mehta, Joel M Gelfand, Miguel Angel Martinez-Gonzalez, Alvaro Gonzalez-Cantero

“…This anti-inflammatory potential has prompted interest in exploring the MedDiet’s role in immune-mediated diseases, including psoriasis. …”
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Oxidative balance score and its association with chronic inflammatory airway diseases and mortality: a population-based study by Zhuanbo Luo, Shiyu Chen, Peixu Chen, Feng Qiu, Weina Huang, Chao Cao

“…ObjectiveThe aim of this research was to explore the possible connection between combined Oxidative Balance Score (OBS) and the prevalence of chronic inflammatory airway diseases (CIAD), including asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis, along with the mortality rate among individuals with CIAD.MethodsData were gathered from the National Health and Nutrition Examination Survey (NHANES) 2013–2018 cycles. …”
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Influence of land cover change on atmospheric organic gases, aerosols, and radiative effects by R. Vella, R. Vella, M. Forrest, A. Pozzer, A. Pozzer, A. P. Tsimpidi, T. Hickler, T. Hickler, J. Lelieveld, J. Lelieveld, H. Tost

“…In this work, a global atmospheric chemistry–climate model, coupled with a dynamic global vegetation model, was employed to study the impacts of perturbing the biosphere through human-induced land use change, thereby exploring changes in BVOC emissions and the atmospheric aerosol burden. …”
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Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systematic network me... by Yuhua Jiang, Yingying Wang, Sijia Ma, Linlin Qian, Yeteng Jing, Xi Chen, Jinsheng Yang

“…BackgroundThe objective of this study is to assess the relative efficacy of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, such as alirocumab, evolocumab, and inclisiran, in conjunction with potent statins like atorvastatin and rosuvastatin, in patients presenting with hyperlipidemia or heightened cardiovascular risk attributable to elevated low-density lipoprotein cholesterol (LDL-C).MethodsA systematic search was conducted across databases including PubMed, Embase, and the Cochrane Library to explore lipid-lowering therapies in hyperlipidemia from their inception to 7 November 2023. …”
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Assessing the Impact of Aldose Reductase (ALR2) Regulatory Gene Polymorphism in Diabetic Retinopathy Patients by Hadiza Rabe Musa, Amina Rabe Musa, Yahuza Gimba Muhammed, Usman Salisu Batagarawa, Aminu Ibrahim

“…There is a crucial need to understand how the polymorphism in the ALR2 gene contributes to diabetic retinopathy.  This study aimed to explore and evaluate the impact of ALR2 gene polymorphism on diabetic retinopathy, alongside assessing inflammatory markers and antioxidant status among diabetic patients residing in Kano State, Nigeria. …”
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Comparative Evaluation of Intra-articular Ozone and Steroid Treatments in Patients with Coxarthrosis under Ultrasound Guidance: A Retrospective Study by Yilmaz Karaduman, Arzu Muz, Azize Serçe, Servi Yildirim, Ismail Eren Durmus, Suna Akin Takmaz

“…Thus, treatment planning should consider the disease stage, and alternative strategies should be explored for advanced cases. Clinicians should prioritise early intervention and seek alternative options for better patient outcomes.…”
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