Endovascular treatment for blood blister ⁃ like aneurysms of internal carotid artery and systematic literature review by ZHOU Lei, WANG Zhong, YANG Guo‐jun, DONG Shi‐biao, LI Nan, ZHU Wei‐wei

“…Objective To explore endovascular treatment for patients with blood blister ⁃ like aneurysms (BBA) of the internal carotid artery (ICA). …”
Get full text

Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome by WANG Xueling, WANG Xueling, ZHONG Peiling, ZHONG Peiling, ZHAO Zhipeng

“…Objective‍　‍To investigate the therapeutic efficacy of artesunate (AS) on polycystic ovary syndrome (PCOS) in mice and explore the potential mechanism primarily. Methods‍　‍Twenty-five female C57BL/6J mice were randomly divided into Control group, model group (PCOS group), low- and high-dose AS groups (AS15 and AS30 groups) and metformin group (Met group). …”
Get full text

Targeted inhibition of Aurora kinase A promotes immune checkpoint inhibition efficacy in human papillomavirus-driven cancers by Pragya Sinha, Faye M Johnson, Soma Ghosh, Jagannadha K Sastry, Madison P O'Hara, Tuhina Mazumdar, Lacin Yapindi

“…In a previous study, we demonstrated that Aurora kinase A (AURKA, Aurora A) inhibitors lead to apoptosis of human HPV-positive cancer cells in vitro and in vivo. Here, we explored the potential of Aurora A inhibition to enhance response to ICIs in immune-competent preclinical models of HPV-driven cancers.Methods We assessed the induction of apoptosis, DNA damage, and immunogenic cell death (ICD) in response to treatment with the Aurora A inhibitor alisertib in vitro and antitumor efficacy of alisertib as a monotherapy and in combination with ICIs that inhibit programmed cell death protein-1 (PD-1) or cytotoxic T-lymphocyte associated protein 4 (CTLA-4) in murine HPV-positive immune-competent tumor models. …”
Get full text

MSCs with upregulated lipid metabolism block hematopoietic stem cell differentiation via exosomal CTP-1A in MDS by Chunlai Yin, Xue Yan, Jinyi Ren, Cheng Zhang, Jiaqing Liu, Zilong Wang, Jing Liu, Weiping Li, Xia Li

“…Elucidating the mechanism underlying the dysfunction of MDS-HSCs is crucial for exploring the pathogenesis of the syndrome. While previous studies have implicated mesenchymal stem cells (MSCs), a principal component of the bone marrow (BM) microenvironment, in the inhibition of normal hematopoiesis, the precise molecular mechanisms have not been fully elucidated. …”
Get full text

The association of serum total bile acids and deep venous thrombosis by Bolin Li, Xinxin Feng, Xinping Kang, Yi Zhao, Miaomiao Cao, Bao Xu, Hui Liu, Shuyi Deng, Yue Wu, Tao Zheng

“…However, there is a paucity of research exploring the relationship between serum total bile acids (TBA) levels and the risk of deep venous thrombosis (DVT) in Chinese individuals. …”
Get full text

A Local Adversarial Attack with a Maximum Aggregated Region Sparseness Strategy for 3D Objects by Ling Zhao, Xun Lv, Lili Zhu, Binyan Luo, Hang Cao, Jiahao Cui, Haifeng Li, Jian Peng

“…The experimental results demonstrate that our attack method achieves both stealth and aggressiveness from different viewpoints. Furthermore, we explore the transferability of the decision regions. …”
Get full text

Functional Characteristics and Lipid Lowering Activity of Auricularia heimuer Soluble Dietary Fiber by Xueyu SHANG, Heriban MEI, Ling SU, Qi WANG

“…The body weight, biochemical indexes, and pathological changes of liver tissue and adipose tissue of HSDF treated obese mice were evaluated, and its lipid-lowering efficacy in obese mouse model was explored. Results showed that the relative molecular weight of HSDF was 4.14×105 Da, which was a mixture of mannose, glucuronic acid, glucose, galactose, xylose and fucose. …”
Get full text

Therapeutic Effect of Neuromuscular Joint Facilitation on Hemiplegia Patients with Cerebral Infarction by LIN Shaoying, YE Li, CHEN Zhenghong

“…ObjectiveTo explore the therapeutic effect of neuromuscular joint faciclitation (NJF) on the upper extremity muscle tone, upper limb and hand motor function and turn over and transfer ability in hemiplegic patients with cerebral infarction.MethodsA total of 136 patients with cerebral infarction treated in the Department of Neurology of the First Affiliated Hospital of Sun Yat-sen University from August 2017 to January 2019 were divided into control group and experimental group according to whether the treatment includes the NJF technique, with 70 and 66 cases in each group, respectively. …”
Get full text

Knowledge, Attitude, and Associated Factors towards Physical Assessment among Nurses Working in Intensive Care Units: A Multicenter Cross-Sectional Study by Bikis Liyew, Ambaye Dejen Tilahun, Tilahun Kassew

“…The result was computed by descriptive statistics and to explore predictors of knowledge, and attitude linear regression analysis models were fitted, and the adjusted unstandardized beta (β) coefficient at 95% CI was used. …”
Get full text

PROSPECTS FOR THE DEVELOPMENT OF BIODIESEL PRODUCTION IN UKRAINE WITH CONSIDERATION OF SOCIO-ECONOMIC AND ENVIRONMENTAL EFFICIENCY by Ihor Kupchuk, Tatiana Yemchyk, Yaroslav Gontaruk

“…The article's objective is twofold: firstly, to explore the prospects for biodiesel production, and secondly, to develop a universal methodology for evaluating its efficiency. …”
Get full text

Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study by Matias Seppälä, Heidi Lukander, Johan Wadén, Marika I. Eriksson, Valma Harjutsalo, Per-Henrik Groop, Lena M. Thorn, FinnDiane Study Group

“…Our aim was to identify clinical factors associated with excessive occupational sitting in type 1 diabetes and, in a prospective setting, to explore its association with cardiovascular events and all-cause mortality, independent of leisure-time physical activity. …”
Get full text

Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease by Jia Mao, Yufei Zhou, Licheng Lu, Ping Zhang, Runhua Ren, Yaqiong Wang, Jing Wang

“…The present study aimed to explore exosomal-associated ceRNA networks in CHD. …”
Get full text

Integrate mathematical modeling for heat dynamics in two-phase casson fluid flow through renal tubes with variable wall properties by P. Deepalakshmi, Adil Darvesh, Hakim AL Garalleh, Manuel Sánchez-Chero, G. Shankar, E.P. Siva

“…The originality of this study lies in the concurrent examination of a generalised two-phase model, partial wall slip, non-Newtonian fluid properties, cross diffusion, magnetic body force, elastic wall behaviour in the presence of debris, and curvature effects in peristaltic urological transport, a comprehensive approach not previously explored. This text highlights several novel aspects of the dynamics of the ureter in two-phase conditions, which are relevant to the usage of magnetic therapy and thermal radiation techniques. …”
Get full text

Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study by Ruei-Hong Li, Tai-Rui Chen, Nicholas D. Gilson, Marius Brazaitis, Yi-Ting Cheng, Hui-Fang Wu, Ji-Hang Lee, Yu-Kai Chang

“…However, the effect of acute CE on inhibitory control, a sub-component of EFs, and P3 amplitude remains inconclusive. Moreover, exploring the mechanisms underlying the effects of acute exercise on EFs contributes to scientific comprehension, with lactate recognized as a crucial candidate positively correlated with EFs. …”
Get full text

Brain development using a multicomponent intravenous lipid emulsion in preterm infants by Katherine M. Ottolini, Julius Ngwa, Sudeepta K. Basu, Kushal Kapse, Melissa Liggett, Jonathan Murnick, Catherine Limperopoulos, Nickie Andescavage

“…Many neonatal intensive care units have transitioned from traditional soybean oil-only to fish oil-containing multicomponent lipid emulsions, but the neurodevelopmental implications have not been well-explored. The primary aim of this study was to assess extrauterine third trimester brain growth in very preterm infants supported with soybean oil-only compared to fish-oil containing multicomponent lipid emulsions; white matter development and neurobehavioral regulation at term were also investigated. …”
Get full text

Healthy aging in frail older adults: Active aging project of a national survey by Jisu Seo, Kyungok Joo, Yuelin Li, Nayoung Kim, Eunna Oh, Lkhagvajav Gansukh, Rhayun Song

“…Health promotion strategies could focus on resilience and social support to empower individuals and strengthen social connectedness, thereby supporting independence in daily life and healthy aging. Further, we need to explore diverse social and cultural activities associated with healthy aging in this population to expand the definition of active aging.…”
Get full text

Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings by Shouming Li, Jingyi Huang, Yunyun Xie, Di Wang, Xin Tan, Yufan Wang

“…These results suggest that modulating the gut microbiota may be a viable therapeutic strategy for managing peanut allergy and highlight the need for further research to explore the clinical implications of these microbial changes.…”
Get full text

New bitongling regulates gut microbiota to predict angiogenesis in rheumatoid arthritis via the gut-joint axis: a deep neural network approach by Yin Guan, Xiaoqian Zhao, Yun Lu, Yue Zhang, Yan Lu, Yue Wang

“…Recent research indicates that gut microbiota might be pivotal in RA development through the “gut-joint axis,” presenting novel therapeutic possibilities.PurposeThis study seeks to explore the therapeutic potential of the traditional Chinese medicine (TCM) compound new bitongling (NBTL) for RA, with an emphasis on its capacity to regulate gut microbiota and suppress angiogenesis via the vascular endothelial growth factor (VEGF) signaling pathway.MethodsWe utilized a collagen-induced arthritis (CIA) rat model to assess the impact of NBTL. …”
Get full text

Challenges of Corporate Misconduct: The Organisational, Social, Economic and Financial Dynamics of Workplace Sexual Harassment in the Restaurant Industry in the USA by Darrell Norman Burrell, Stacey L. Morin, Theresia Wansi, Virginia Bianco Mathis, Carlo Ninassi, Susanne Ninassi

“…Unlike previous studies focusing only on theoretical approaches to sexual harassment, this research adopts real-world and practical approaches, such as analyzing workplace policies and exploring current research, to understand the unique vulnerabilities of the restaurant industry and the broader implications for employee well-being and organizational stability. …”
Get full text

Short- and long-term changes in neurological, behavioural, and blood biomarkers following repeated mild traumatic brain injury in rats—potential biological sex-dependent effects by Rodrigo Moraga-Amaro, Oscar Moreno, Jordi Llop, Marion Bankstahl, Marion Bankstahl, Jens P. Bankstahl

“…As biological sex is suggested to be a major confounding factor, we explored how sex influences behavioural and candidate blood biomarkers during CTE-like progression following experimental rmTBI.MethodsTo induce CTE-like development, we subjected male and female rats to three mTBIs at a 5-day interval. …”
Get full text