CHA2DS2-VASc Score Is Associated With Prognosis in Patients With Acute Ischemic Stroke Without Atrial Fibrillation by Mingjuan Song, MM, Xu Chen, MD

“…Background: Although the prognostic value of the CHA2DS2-VASc (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke or transient ischemic attack, vascular disease, age 65-74 years, and female sex) scoring system in patients with stroke has been explored in several studies, a research gap exists in its application, especially in patients without atrial fibrillation (AF). …”
Get full text

Analysis of the demand and influencing factors of the family members of children with cardiovascular diseases in a certain hospital in Jinan (济南市某三甲医院心血管病患儿家属对居家医养护需求及影响因素分析)... by MOU Xiao (牟啸)

“…Objective To explore the demand of family members of children with cardiovascular diseases for home care and analyze the influencing factors. …”
Get full text

Psychometric characteristics and feasibility of microinteraction-based Ecological Momentary Assessment in audiology research by Yu-Hsiang Wu, Elizabeth Stangl, Samuel Smith, Jacob Oleson, Christi Miller, Octav Chipara

“…Additional research is needed to explore the potential applications of micro-EMA in audiology research.…”
Get full text

Ultrasound stimulated perfluorobutane microbubbles cavitation enhanced the therapeutic effect of colchicine in rats with acute gouty arthritis by Ji-cheng Zhang, Bo Gou, Tian-rui Wang, Wan-tai Dang, Yan-hui Li, Wen Wen, Jian Liu

“…Objective: This study aimed to explore whether cavitation generated by ultrasound-stimulated microbubbles (USMB) can enhance the therapeutic efficacy of colchicine and diminish its gastrointestinal side effects in rats with acute gouty arthritis (AGA). …”
Get full text

Machine learning prediction of anxiety symptoms in social anxiety disorder: utilizing multimodal data from virtual reality sessions by Jin-Hyun Park, Yu-Bin Shin, Dooyoung Jung, Ji-Won Hur, Seung Pil Pack, Heon-Jeong Lee, Hwamin Lee, Chul-Hyun Cho, Chul-Hyun Cho

“…The best parameters were explored through grid search or random search, and the models were validated using stratified cross-validation and leave-one-out cross-validation.ResultsThe CatBoost, using multimodal features, exhibited high performance, particularly for the Social Phobia Scale with an area under the receiver operating characteristics curve (AUROC) of 0.852. …”
Get full text

Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study by Changjiang Li, Shun Zhao, Yingkai Li, Songyuan He, Wen Jian, Yanci Liu, Zichao Cheng, Hongyu Peng

“…Cox proportional hazards regression models were adopted to explore the relationship between the TyG index and MACEs. …”
Get full text

Identification of Differentially Expressed Genes in Metastatic and Non-Metastatic Nasopharyngeal Carcinoma Cells by Suppression Subtractive Hybridization by Xu-Yu Yang, Cai-Ping Ren, Lei Wang, Hui Li, Chun-Jie Jiang, Hong-Bo Zhang, Ming Zhao, Kai-Tai Yao

“…The aim of this study was to explore possible NPC gene candidates that may play key roles in NPC metastasis. …”
Get full text

Owners’ perceptions of dog treat management in Western Romania by Sorana Daina, Anamaria Blaga-Petrean, Silvana Popescu, Ioana Delia Pop, Daniel Mierlita, Adrian Macri

“…The wide range and availability of these products often pair with the fondness of owners for their companions, leading to overfeeding them with rewards.MethodsThis study explored owner treat provision behaviors among 890 voluntarily participating dog owners in Western Romania through an online survey conducted between June and November 2023.ResultsThe majority of respondents were women (72%) and younger adults aged 18–24 (39%). …”
Get full text

The effects of PM2.5 components on the cardiovascular disease admissions in Shanghai City, China: a multi- region study by Wanying Su, Heping Liu, Tiantian Han, Yunyun Wang, Yi An, Yan Lin

“…Although many studies have investigated the association of particulate pollution with CVD, the effect of finer particulate pollution components on CVD remains unclear. This study aimed to explore the effect of five PM2.5 components ( $$\:{\text{SO}}_{\text{4}}^{\text{2-}}$$ , sulfate; $$\:{\text{NO}}_{\text{3}}^{\text{-}}$$ , nitrate; $$\:{\text{NH}}_{\text{4}}^{\text{+}}$$ , ammonium; OM, organic matter; BC, carbon black) on CVD admission in Shanghai City, identify the susceptible population, and provide clues for the prevention and control of particulate pollution. …”
Get full text

HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model by Yi-fu He, Xi-min Hu, Md. Asaduzzaman Khan, Bo-yao Yu, Yi-cun Sheng, Xian-zhong Xiao, Xin-xing Wan, Si-pin Tan, Kun Xiong

“…In this research, we try to explore the relationship between HSF1 and NLRP3 in a sepsis model and try to reveal the mechanism of HSF1 inhibiting the process of brain injury. …”
Get full text

Health recommender systems to facilitate collaborative decision-making in chronic disease management: A scoping review by Antonia Barbaric, Kenneth Christofferson, Susanne M Benseler, Chitra Lalloo, Alex Mariakakis, Quynh Pham, Joost F Swart, Rae S M Yeung, Joseph A Cafazzo

“…Recognizing the importance of collaborative decision making (CDM) and patient engagement in chronic disease treatment, this review explored how HRSs support patients in managing their illness. …”
Get full text

Influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and establishment of nomogram model by Ganlin Wu, Ganlin Wu, Yanli Ye, Meirong Xu, Yanxia Zhang, Zuopeng Lu, Lv Huang

“…PurposeTo explore the influencing factors of acute kidney injury in elderly patients with diabetic nephropathy and to construct a nomogram model.MethodsThe research subjects were 680 patients with type 2 diabetic nephropathy admitted to our hospital. …”
Get full text

Surgical interventions for degenerative cervical disease: Impact on patient quality of life, mental health, pain relief, and spiritual health by Ching-Ya Huang, Cheng-Shyuan Rau, Jo-Chien Lin, Shiun-Yuan Hsu, Ching-Hua Hsieh

“…While surgical intervention is a common treatment, its impact on holistic well-being, including spiritual health, has not been thoroughly explored. This study aimed to evaluate the effects of surgery on QOL, pain-related disability, mental health, and spiritual well-being in patients with degenerative cervical diseases. …”
Get full text

The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells by Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin

“…In this study, we established an in vitro model of Cu²⁺-exposed (0, 15, 30, 60 and 120 μM) SH-SY5Y cells to explore the role of autophagy in copper-induced developmental neurotoxicity. …”
Get full text

Protective effects of berbamine against arginase-1 deficiency-induced injury in human brain microvascular endothelial cells by Xiaolan Wei, Weiwei Li, Zixuan Chen, Jintu Chen, Yun Chen, Jiangping Cai, Huasong Lin

“…We examined the effects of ARG1 expression levels on HCMEC/D3 cell viability, migration, apoptosis, adhesion, and angiogenesis through cellular experiments. Additionally, we explored how ARG1 expression levels influenced arginine (Arg), nitric oxide (NO), and ROS levels in HCMEC/D3 cells. …”
Get full text

Evaluating Reaction Videos of Young People Watching Edutainment Media (MTV Shuga): Qualitative Observational Study by Venetia Baker, Sarah Mulwa, David Khanyile, Georgia Arnold, Simon Cousens, Cherie Cawood, Isolde Birdthistle

“…Reaction videos, a popular format in web-based culture in which users film themselves reacting to television shows, can be adapted as a research method for immediate and unfiltered insights into young people’s engagement with edutainment media. ObjectiveWe explored how physical and social context influences young people’s engagement with MTV Shuga, a dramatic television series based on sexual health and relationships among individuals aged 15 to 25 years. …”
Get full text

Therapeutic potential of Chromolaena odorata, Vernonia amygdalina, and Cymbopogon citratus against pathogenic Bacteria by Udensi Justina Ugochi, Anyanwu Charles Obinna, Emedoh Andrew Emeka, Anyanwu Emilia Oluchi, Danladi Makeri, Pius Theophilus, Ezera Agwu

“…The increasing ineffectiveness of traditional antibiotics has intensified the need to explore medicinal plants as viable therapeutic options. …”
Get full text

Bibliometric analysis and review of food waste management via sustainable approaches by U. Danya, M. Kamaraj, P. Suresh Babu, J. Aravind

“…Various valorization pathways that convert food waste into biofuels, biochemicals, and bio-based materials are explored, thereby integrating principles of the circular economy to minimize waste and maximize resource utilization. …”
Get full text

FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis by Yu Cheng, Yang Jiao, Wan Wei, Mengjia Kou, Yaodong Cai, Yang Li, Hao Li, Tonghua Liu

“…The roles of Erastin and the SIRT3 inhibitor 3-TYP were also explored to elucidate FBR2’s mechanisms of action.ResultsFBR2 treatment significantly mitigated BLM-induced lung injury in mice, as evidenced by improved body weight and survival rates, and reduced levels of inflammatory cytokines, including IL-6 and TNF-α. …”
Get full text

The prebiotic potential of dietary onion extracts: shaping gut microbial structures and promoting beneficial metabolites by Yebeen Yoo, Seongok Kim, WonJune Lee, Jinwoo Kim, Bokyung Son, Kwang Jun Lee, Hakdong Shin

“…ABSTRACT Onions are well-known vegetables that offer various health benefits. This study explores the impact of onion extracts on gut microbiome using an in vitro fecal incubation model and metabolome analysis. …”
Get full text