Gcn2 rescues reprogramming in the absence of Hog1/p38 signaling in C. neoformans during thermal stress by David Goich, Amanda L. M. Bloom, Sean R. Duffy, Maritza N. Ventura, John C. Panepinto

“…Thus, there is a critical need to identify additional targets that play a role in the adaptation to the human host and virulence. This study explores the role of the stress response kinases Hog1 and Gcn2 in thermoadaptation, which is a pre-requisite for virulence. …”
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Hyperspectral inversion of heavy metal content in farmland soil under conservation tillage of black soils by Yanan Chen, Wanying Shi, Guzailinuer Aihemaitijiang, Feng Zhang, Jiquan Zhang, Yichen Zhang, Dianqi Pan, Jinying Li

“…Focusing on the black area region of Jilin Province, this study explored the correlation between three HMs, namely copper, zinc, and cadmium, and organic substances, clay minerals, and ferromanganese oxides through an in-depth analysis of soil samples using soil reflectance spectrometry. …”
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Evaluating the Effectiveness of a Multimodal Psychotherapy Training Program for Medical Students in China: Protocol for a Randomized Controlled Trial by Tao Pei, Yinan Ding, Jinsong Tang, Yanhui Liao

“…Pearson correlations and regression analysis explored factors associated with the knowledge score at baseline. …”
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Association between the cumulative estimated glucose disposal rate and incident cardiovascular disease in individuals over the age of 50 years and without diabetes: data from two l... by Jin Zhang, Ziyi Sun, Yufei Li, Yuhan Yang, Wenjie Liu, Mengwen Huang, Kuiwu Yao

“…Objective The aim of this study was to explore whether long-term cumulative eGDR was independently associated with incident CVD in individuals over the age of 50 years and without diabetes. …”
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An exploratory study of serum creatine kinase as a prognostic marker for patients with resectable pancreatic cancer: looking into the relationship with body composition by Cong Chen, Xin Luo, Xianchao Lin, Ronggui Lin, Yuanyuan Yang, Congfei Wang, Haizong Fang, Tianhong Teng, Heguang Huang, Fengchun Lu

“…Body composition was analyzed based on preoperative abdominal CT images to explore the sex-specific associations between skeletal muscle area (SMA) and serum CK levels. …”
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Impact of Lower-Volume Training on Physical Fitness Adaptations in Team Sports Players: A Systematic Review and Meta-analysis by Filipe Manuel Clemente, Rodrigo Ramirez-Campillo, Jason Moran, Piotr Zmijewski, Rui Miguel Silva, Morten Bredsgaard Randers

“…Abstract Background A small number of reviews have explored lower- versus higher-volume training in non-athletes, but the growing challenge of congested schedules in team sports highlights the need to synthesize evidence specific to team sport athletes. …”
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Rapid assessment of pre-service midwifery education in conflict settings: findings from a cross-sectional study in Nigeria and Somalia by Emilia Iwu, Shatha Elnakib, Hawa Abdullahi, Rejoice Helma Abimiku, Charity Maina, Asia Mohamed, Kazeem Olalekan Ayodeji, George Odonye, Rifkatu Sunday, Maryan Abdulkadir Ahmed, Mohamed Ahmed Omar, Abdirisak A. Dalmar, Emilie Grant, Hannah Tappis

“…This study sought to assess the extent to which midwifery pre-service education programs meet national and global standards, and to explore how conflict affects pre-service midwifery education in Yobe State Nigeria and the Benadir and Galgaduud regions of Somalia. …”
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Hippocampal Functional Radiomic Features for Identification of the Cognitively Impaired Patients from Low-Back-Related Pain: A Prospective Machine Learning Study by Yang Z, Liang X, Ji Y, Zeng W, Wang Y, Zhang Y, Zhou F

“…Finally, we further analyzed the relationship between the hippocampal functional radiomic features and clinical measures, to explore the clinical significance of these features.Results: The combined radiomic features model logistic regression algorithm superior performance in distinguishing cognitively impaired patients from LBLP (AUC = 0.970, accuracy = 92.3%, sensitivity = 92.3%, specificity = 92.3%) compared to the other models. …”
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Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…Conclusion We have uncovered HDAC6 as a promising molecular vulnerability that should be explored to treat RR-HNC.…”
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Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma by Huai-Yu Wu, Shu-Ya Cao, Zheng-Gang Xu, Tian- Wang, Gu-Wei Ji, Ke Wang

“…HCC single-cell data obtained from Gene Expression Omnibus (GEO) were used to map gene signatures and explore inter-cellular signaling communications. Finally, a radiogenomic signature was used to predict the objective response rate (ORR) and overall survival (OS). …”
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The association between dietary omega-3 intake and osteoporosis: a NHANES cross-sectional study by Zhiwen Liu, Shaoming Cai, Yuzhen Chen, Zijing Peng, Huanling Jian, Zhihai Zhang, Hongxing Huang

“…Multivariate logistic regression and subgroup analysis were used to explore the correlation between dietary omega-3 intake and osteoporosis. …”
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Forecasting the Incidence of Mumps Based on the Baidu Index and Environmental Data in Yunnan, China: Deep Learning Model Study by Xin Xiong, Linghui Xiang, Litao Chang, Irene XY Wu, Shuzhen Deng

“…Feature selection was conducted using Pearson correlation analysis, and lag correlations were explored through a distributed nonlinear lag model (DNLM). …”
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Trisomy 21 screening with αlpha software and the Fetal Medicine Foundation algorithm by L Pistorius, C A Cluver, I Bhorat, L Geerts

“…More research is needed in the SA setting to explore why screening and confirmatory testing after high-risk results are not performed in many pregnancies. …”
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Separation of Short-Chain Fatty Acids from Primary Sludge into a Particle-Free Permeate by Coupling Chamber Filter-Press and Cross-Flow Microfiltration: Optimization, Semi-Continuo... by Nikhil Shylaja Prakash, Peter Maurer, Harald Horn, Florencia Saravia, Andrea Hille-Reichel

“…This pilot-scale study addresses this limitation and explores the recovery of SCFAs from primary sludge into a particle-free permeate through a combination of chamber filter-press (material: polyester; mesh size: 100 µm) and cross-flow microfiltration (material: α-Al₂O₃; pore size: 0.2 µm; cross-flow velocity: 3 m∙s⁻¹; pressure = 2.2 bars). …”
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Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post‐operative dysfunction? by Márton Tokodi, Endre Németh, Bálint K. Lakatos, Erika Kispál, Zoltán Tősér, Levente Staub, Kristóf Rácz, Ádám Soltész, Szabolcs Szigeti, Tamás Varga, János Gál, Béla Merkely, Attila Kovács

“…Abstract Aims The PREPARE‐MVR study (PRediction of Early PostoperAtive Right vEntricular failure in Mitral Valve Replacement/Repair patients) sought to investigate the alterations of right ventricular (RV) contraction pattern in patients undergoing mitral valve replacement/repair (MVR) and to explore the associations between pre‐operative RV mechanics and early post‐operative RV dysfunction (RVD). …”
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The Malayan Landscape Paintings by Sarena Abdullah, Yuen Beng Lee

“…Landscape can be considered the most significant and intrinsic pictorial form in modern Malaysian art, as it was one of the earliest mediums of visual impressions and expressions. This article explores the evolution of the representation of Malaysia in landscape paintings from the early 19th century to mid-20th century by examining selected works and discussing how these artistic renditions reflect the changes that were happening in Malaya, from the types of landscapes produced by British artist-officers to how the British government mooted the Malayan cultural strategy to gain public trust and confidence in their ability to combat insurgency. …”
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A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores by Vasanop Vachiramon, Sonphet Chirasuthat, Suphagan Boonpethkaew, Nawara Sakpuwadol, Tanat Yongpisarn, Natthachat Jurairattanaporn

“…Various treatment modalities have been explored to address this issue. This study focuses on the efficacy and safety of combining Onabotulinumtoxin A (OnaBoNT-A) and hyaluronic acid filler (HA filler) to target enlarged facial pores in Asians. …”
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Optimal vocal therapy for respiratory muscle activation in patients with COPD: effects of loudness, pitch, and vowels by Zhengtong Qiao, Ziwei Kou, Jiazhen Zhang, Daozheng Lv, Dongpan Li, Xuefen Cui, Kai Liu

“…However, variations in singing treatment protocols have led to inconsistent clinical outcomes.ObjectiveThis study aims to explore the content of vocalization training for patients with COPD by observing differences in respiratory muscle activation across different vocalization tasks.MethodsAll participants underwent measurement of surface electromyography (sEMG) activity from the sternocleidomastoid (SCM), parasternal intercostal muscle (PARA), seventh intercostal muscle (7thIC), and rectus abdominis (RA) during the production of the vowels/a/,/i/, and/u/at varying pitches (comfortable, +6 semitones) and loudness (−10 dB, +10 dB) levels. …”
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Patterns of interpopulation variation and physiological trade-offs of the acute thermal tolerance of juvenile Chinook salmon (Oncorhynchus tshawytscha) by Kenneth W. Zillig, Kenneth W. Zillig, Heather N. Bell, Alyssa M. FitzGerald, Alyssa M. FitzGerald, Nann A. Fangue

“…IntroductionThe capacity of species and populations to respond to rapid environmental change will be pivotal for their resilience in the coming decades. To explore thermal plasticity, physiological trade-offs, and associations with environmental characteristics, we assessed the heat hardening response and acclimation capacity of juvenile Chinook salmon (Oncorhynchus tshawytscha) from seven hatchery populations spanning diverse ecoregions along the West Coast of the United States.MethodsProgeny from each population were acclimated to one of three temperatures (11, 16, or 20°C) and subjected to two acute thermal maximum (CTMAX) trials 24 h apart. …”
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Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients by Hong Zhao, Xiangrui Li, Xiaoyue Liu, Chenan Liu, Xin Zheng, Yue Chen, Jinyu Shi, Qiteng Liu, Zhaoting Bu, Hanping Shi

“…Correlation analysis, Kaplan–Meier method, and restricted cubic spline analysis were conducted to explore ACR's relationship with overall survival (OS). …”
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