Showing 1 - 14 results of 14 for search '"experimental evolution"', query time: 0.04s Refine Results
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    The impact of antioxidant-ciprofloxacin combinations on the evolution of antibiotic resistance in Pseudomonas aeruginosa biofilms by Doaa Higazy, Marwa N. Ahmed, Oana Ciofu

    Published 2024-12-01
    “…This study investigates whether antioxidants (AOs) such as N-acetyl-cysteine (NAC) and Edaravone (ED) can reduce AMR in Pseudomonas aeruginosa biofilms exposed to sub-inhibitory concentrations of ciprofloxacin (CIP). In vitro experimental evolution studies were conducted using flow cells and glass beads biofilm models. …”
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  9. 9

    Chemical signals and social structures strengthen sexual isolation in Drosophila pseudoobscura by Jacob A. Jezovit, Joel D. Levine

    Published 2025-01-01
    “…Here we show through an experimental evolution study that six generations of selection in experimental sympatry led to the divergence of social structures measured in Drosophila pseudoobscura and Drosophila persimilis flies. …”
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    Hypermutability bypasses genetic constraints in SCV phenotypic switching in Pseudomonas aeruginosa biofilms by Romina A. Tobares, Román A. Martino, Claudia A. Colque, Gaston L. Castillo Moro, Alejandro J. Moyano, Andrea G. Albarracín Orio, Andrea M. Smania

    Published 2025-01-01
    “…This study explores the adaptive mechanisms behind the phenotypic switching between Small Colony Variants (SCVs) and revertant states in P. aeruginosa biofilms, emphasizing hypermutability due to Mismatch Repair System (MRS) deficiencies. Through experimental evolution and whole-genome sequencing, we show that both wild-type and mutator strains undergo parallel evolution by accumulating compensatory mutations in factors regulating intracellular c-di-GMP levels, particularly in the Wsp and Yfi systems. …”
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    Neutral drift upon threshold-like selection promotes variation in antibiotic resistance phenotype by Ayşe Nisan Erdoğan, Pouria Dasmeh, Raymond D. Socha, John Z. Chen, Benjamin E. Life, Rachel Jun, Linda Kiritchkov, Dan Kehila, Adrian W. R. Serohijos, Nobuhiko Tokuriki

    Published 2024-12-01
    “…We perform long-term experimental evolution on VIM-2 β-lactamase, an antibiotic-resistance enzyme, to explore the conditions that promote the emergence and maintenance of phenotypic variation. …”
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    Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis by Guicharnaud, Chloé, Groussier, Géraldine, Beranger, Erwan, Lamy, Laurent, Vercken, Elodie, Dahirel, Maxime

    Published 2023-06-01
    “…To understand how life-history traits and effective dispersal covary, we measured these traits in controlled conditions for 28 lines from five species of Trichogramma, which are small endoparasitoid wasps frequently used as a biological model in experimental evolution but also in biocontrol against Lepidoptera pests. …”
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    Sterol‐Targeted Laboratory Evolution Allows the Isolation of Thermotolerant and Respiratory‐Competent Clones of the Industrial Yeast Saccharomyces cerevisiae by Isabel‐Elena Sánchez‐Adriá, Jose A. Prieto, Gemma Sanmartín, Miguel Morard, Estéfani García‐Ríos, Francisco Estruch, Francisca Randez‐Gil

    Published 2025-01-01
    “…In conclusion, our experimental evolution generated thermotolerant and fully competent strains and identified factors that could influence fluconazole and heat growth.…”
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    A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti by Bacot, Tiphaine, Haberkorn, Chloe, Guilliet, Joseph, Cattel, Julien, Kefi, Mary, Nadalin, Louis, Filee, Jonathan, Boyer, Frederic, Gaude, Thierry, Laporte, Frederic, Tutagata, Jordan, Vontas, John, Dusfour, Isabelle, Bonneville, Jean-Marc, David, Jean-Philippe

    Published 2024-11-01
    “…The involvement of this P450 duplication in deltamethrin survival was supported by a significant phenotypic response to the P450 inhibitor piperonyl butoxide together with genotype-phenotype association and RNA interference. Experimental evolution suggested that this P450 duplication is associated with a significant fitness cost, potentially affecting its adaptive value in presence of other resistance alleles. …”
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