Improving Mental Health and Well-Being Through the Paradym App: Quantitative Study of Real-World Data by Athina Marina Metaxa, Shaun Liverpool, Mia Eisenstadt, John Pollard, Courtney Carlsson

“…There is also a dearth of research on well-being apps structured around users’ lived experiences and emotional patterns and a lack of integration of real-world evidence of app usage. …”
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Aspergillus fumigatus Influences Gasdermin-D-Dependent Pyroptosis of the Lung via Regulating Toll-Like Receptor 2-Mediated Regulatory T Cell Differentiation by Wei Yan, Yi-si Zhao, Ke Xie, Yu Xing, Fang Xu

“…Compared with that of wild-type mice, the fungal burden in the lung of TLR2-deficient mice was reduced and the knockout of TLR2 changed the expression of GSDMD, IL-1α, and IL-1β in A. fumigatus. In in vitro experiments, we found that the inhibition of TLR2 can reduce Treg differentiation. …”
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iRGD-Targeted Biosynthetic Nanobubbles for Ultrasound Molecular Imaging of Osteosarcoma by Liu T, Liang X, Liu W, Yang S, Cui T, Yan F, Li Z

“…Our in vitro and in vivo experiments showed the specifically binding ability of iRGD-sGVs to both vascular endothelial cells and tumor cells, producing the stronger and longer acoustic signals in tumors in comparison with the control probe. …”
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Utilisation of the Innovative [18F]-Labelled Radiotracer [18F]-BIBD-071 Within HR+ Breast Cancer Xenograft Mouse Models by Di Fan, Xin Wang, Xueyuan Ling, Hongbin Li, Lu Zhang, Wei Zheng, Zehui Wu, Lin Ai

“…MicroPET/CT imaging was conducted after injection of the tracer at 1 and 2 h, and a blocking study was also conducted using the aromatase inhibitor letrozole. A block experiment was used to prove the specificity of the probe. …”
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Characterization and Spatial Distribution of Sand Group Architecture and Channel Types in Tight Gas Reservoirs: A Case Study From the Jurassic Shaximiao Formation of the Jinqiu Gas... by Guian Guo, Deyu Zhu, Xiaojuan Wang, Mingqiu Li, Xu Guan, Xiaoju Zhang, Changjiang Wu, Shaomin Zhang, Li Hu, Juan Zhao, Nan Li, Huiqiang Wang, Bohan Duan

“…In this study, data from drilling cores, logs, seismic, and experiment testing were used to investigate the spatial distribution of sand group architecture and the channel types. …”
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Effects of Consuming Pulsed UV Light-Treated <i>Pleurotus citrinopileatus</i> on Vitamin D Nutritional Status in Healthy Adults by Chih-Ching Hsu, Chiao-Ming Chen, Yu-Ming Ju, Yu-Ching Wu, Huei-Mei Hsieh, Shu-Hui Yang, Chien-Tien Su, Te-Chao Fang, Widiastuti Setyaningsih, Sing-Chung Li

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Integrating single-cell RNA-Seq and bulk RNA-Seq data to explore the key role of fatty acid metabolism in hepatocellular carcinoma by Hua Dai, Xin Tao, Yuansen Shu, Fanrong Liu, Xiaoping Cheng, Xiushen Li, Bairui Shu, Hongcheng Luo, XuXiang Chen, Zhaorui Cheng

“…Molecular docking analysis indicated that etoposide, methotrexate, and doxorubicin could effectively bind to PTGES3. In vitro experiments confirmed that PTGES3 knockdown significantly impaired the proliferation, invasion, and migration of HCC cells. …”
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Projected distribution patterns of Alpinia officinarum in China under future climate scenarios: insights from optimized Maxent and Biomod2 models by Yong Kang, Yong Kang, Fei Lin, Junmei Yin, Junmei Yin, Yongjie Han, Min Zhu, Yuhua Guo, Fenling Tang, Yamei Li

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Determining the Factors and Evolutionary Trends of Customer Engagement in Businesses: A Bibliometric Analysis by Reza Abbasi Mobarakabadi, Amir khanlari, Nader Seyyedamiri

“…Based on this, engagement is defined as the interaction and creative experiences of the customer with the brand. This pathway is rapidly evolving from a micro to macro perspective and new research is likely to focus on all actors in a service eco-system.…”
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Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection by Yin H, Li X, Lu D, Zhao X, Yang Z, Wang Z, Xu F, Chen Y, Li C

“…This study aimed to investigate the role of MR-1 and ROCK1 in the regulation of inflammation in AD and their potentialities as therapeutic targets.Methods: Researchers performed protein immunoblotting on aortic wall tissue from 10 patients who underwent aortic arch replacement and 10 patients who underwent coronary artery bypass grafting to examine the expression levels of MR-1, ROCK1, and inflammatory pathways in the aortas. In vitro experiments, human aortic smooth muscle cells were extracted, and an in vitro dissection model was constructed with angiotensin II. siRNA silencing studies were performed to investigate the effects of MR-1 and ROCK1 on the development of AD and their interconnections.Results: Analysis of aortic tissues revealed significantly elevated levels of MR-1 and ROCK1 in AD patients, and meanwhile the inflammatory indexes showed the same trend. …”
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The Mechanisms of Guaranteeing the Right to Clean Air in Iran and International Documents by Fatemeh Hamidi, Maryam Afshari, Ali Mashhadi

“…Therefore, taking measures to reform the existing structures based on scientific principles and applying the laws and experiences of other countries in the world to deal with air pollution are among the main priorities. …”
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Penerapan Logika Fuzzy Dan Metode Profile Matching Pada Sistem Pakar Medis Untuk Diagnosis Covid-19 Dan Penyakit Lain by Rusliyawati Rusliyawati, Agus Wantoro, Erliyan Redy Susanto

“…The patient feels pain in the nose and throat and experiences coughing and sneezing. Diagnosis using CT-Scan produces radiation that can increase the risk of cancer because the patient receives doses of substances containing iodine which can cause allergic reactions such as metallic taste in the mouth, itching, and shortness of breath. …”
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Gambaran Pengetahuan dan Sikap Mahasiswa Fakultas Kedokteran Universitas Andalas tentang Rokok by Yosantaraputra ., Yanwirasti ., Abdiana .

“…The results of the study show that respondent’s knowledge towards Cigarette is the good category 0,4%, the average category 64,5%, and the less category 35,1%. The experiment’s result on respondent’s attitude to wards Cigarette is the good category 90,1%, the average category 9,5% and the less category 0,4%. …”
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Unraveling Online Mental Health Through the Lens of Early Maladaptive Schemas: AI-Enabled Content Analysis of Online Mental Health Communities by Beng Heng Ang, Sujatha Das Gollapalli, Mingzhe Du, See-Kiong Ng

“…Personality disorders reflected themes of subjugation (OR 2.51, 95% CI 1.86-3.39; P<.001), while posttraumatic stress disorder problems involved distressing experiences and mistrust (OR 5.04, 95% CI 4.49-5.66; P<.001). …”
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DepITCM: an audio-visual method for detecting depression by Lishan Zhang, Lishan Zhang, Zhenhua Liu, Yumei Wan, Yunli Fan, Diancai Chen, Qingxiang Wang, Kaihong Zhang, Yunshao Zheng

“…Furthermore, inspired by multi-task learning strategies, this paper enhances the primary task of depression classification by incorporating a secondary task (regression task) to improve overall performance.ResultsWe conducted experiments on the AVEC2017 and AVEC2019 datasets. The results show that, in the classification task, our method achieved an F1 score of 0.823 and a classification accuracy of 0.823 on the AVEC2017 dataset, and an F1 score of 0.816 and a classification accuracy of 0.810 on the AVEC2019 dataset. …”
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Temu Kembali Citra Tenun Nusa Tenggara Timur menggunakan Esktraksi Fitur yang Robust terhadap Perubahan Skala, Rotasi, dan Pencahayaan by Budiman Baso, Nanik Suciati

“…Whereas to overcome the lighting variations in the image, image quality improvement is done by using Contrast Limited Adaptive Histogram Equalization (CLAHE). The experiment was conducted by comparing the performance of the BoVW representation which was built using the SURF feature with Maximally Stable Extremal Regions (MSER) at the tenun image retrieval. …”
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Impact of school salad bars on fruit and vegetable selection, intake, and waste in Mid-Atlantic elementary schools by Melanie K. Bean, Suzanne E. Mazzeo, Lilian de Jonge, Laura Thornton, Hollie Raynor, Ashley Mendoza, Sarah Farthing, Bonnie Moore

“…Abstract Background Few studies have empirically examined the impact of school salad bars on elementary students’ fruit and vegetable (FV) consumption within the National School Lunch Program (NSLP). This natural experiment evaluated the impact of salad bars on FV selection, intake, and waste within elementary schools. …”
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Effects of Honey Supplementation in Female Brood Feed on Male and Female Percentages, Growth, and Survival Rate of Crayfish Red Claw (Cherax quadricarinatus) Seed by Akhmad Taufiq Mukti

“…The method that used in this study was laboratory scale experiment. The treatments that was applied were addition of honey dosages in female brood feed of crayfish red claw, i.e. 0 (control), 50, 100, 150, 200, 250 and 300 ml/kg feed. …”
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Performance evaluation model of the narrators of Rahian Noor camps. by Abbas Alwardi, Mohammad Mahdi Mohtadi, Mohammadjavad Pahlevanzadeh, Amirhossein Saffarinia, Mohammad Reza Fathi

“…Purpose: During the past years and after the holy defense, one of the biggest cultural events of the country that caused the transfer of experiences and retelling of the historical events and sacrifices of the warriors of Islam during the eight years of the holy defense was Rahian Noor. …”
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Intervening Non-Small-Cell Lung Cancer Progression by Cell Membrane Coated Platycodin D via Regulating Hsa-miR-1246/FUT9/GSK3&beta; Pathway by Zheng S, Xie Z, Zhou Z, Wang S, Xin Y, Lin J, Cheng K, Lu T, Qi R, Guo Y

“…Furthermore, a homologous cell membrane-based PD delivery system was established to improve the biosafety and efficacy of PD in vivo.Results: Hsa-miR-1246 was upregulated by PD treatment, and functional experiments demonstrated that the miR-1246-mimic enhanced PD’s suppressive effects on NSCLC cell proliferation, colony formation, migration, and invasion, while the miR-1246-inhibitor abrogated these effects. …”
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