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1442
SARS-CoV-2 Evolution: Implications for Diagnosis, Treatment, Vaccine Effectiveness and Development
Published 2024-12-01“…SARS-CoV-2 is characterized by rapidly evolving mutations, especially in (but not limited to) the spike protein, complicating predictions about its evolutionary trajectory. These mutations have significantly affected transmissibility, immune evasion, and vaccine efficacy, leading to multiple pandemic waves with over half a billion cases and seven million deaths globally. …”
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1443
Relationship between weapon size and six key behavioural and physiological traits in males of the European earwig
Published 2024-06-01“…Overall, these results challenge our current understanding of the function and quality signal of forceps length in this species and raise questions about the evolutionary drivers that could explain the maintenance of weapon size diversity within and between populations.…”
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1444
Evaluation of fluorinated phospholipid analogs: A study on ADMET profiles, molecular docking and dynamics simulation in anticancer therapy
Published 2025-01-01“…Functional annotation and phylogenetic investigation affirmed the evolutionary conservation and pivotal biological function of heat shock protein (HSP70KDa1A). …”
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1445
Dose-dependent role of AMH and AMHR2 signaling in male differentiation and regulation of sex determination in Spotted knifejaw (Oplegnathus punctatus) with X1X1X2X2/X1X2Y chromosom...
Published 2025-02-01“…Abstract Sex determination mechanisms vary significantly across different chromosomal systems and evolutionary contexts. Nonetheless, the regulatory framework governing the multi-sex chromosome system (X1X1X2X2/X1X2Y) remains enigmatic. …”
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1446
Nucleosome patterns in four plant pathogenic fungi with contrasted genome structures
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1447
Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato
Published 2025-01-01“…The collinearity between SlbHLHs and interrelated orthologs from 10 plants further revealed evolutionary insights into <i>SlbHLHs</i>. Cis-element investigations of <i>SlbHLHs</i> promotors further suggested the potential roles of <i>SlbHLHs</i> in tomato development and stress responses. …”
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1448
Intraspecific Morphometric Variation in a New Species of <i>Ceratomyxa</i> Thélohan 1892 (Cnidaria) from the South Atlantic Ocean: An Ecomorphological Study Using Geometric Morphom...
Published 2025-01-01“…The work highlights the utility of GM in advancing the understanding of myxozoan morphology and its evolutionary implications and emphasizes the need for further research on myxospore shape evolution and its ecological and adaptive significance in natural populations.…”
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1449
New View on the Genesis of the Bashuihe Pluton, Laoshan Granites, China: Indications from Fluid Inclusions and H–O Isotopes
Published 2021-01-01“…This study conducted microthermometry and stable isotope analysis of quartz inclusions from oval caves and host rocks from the Bashuihe pluton to reconstruct the diagenetic evolutionary history of the Laoshan area. The temperature measurement results indicated a homogenisation temperature range from 162.5 to 261.6°C (mean 203.9°C), a salinity range of 2.1–8.3 wt% (mean 5.07 wt%), and a density range of 0.8–0.98 g/cm3 (mean 0.90 g/cm3), indicating a low-temperature, low-salinity, and low-density fluid. …”
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1450
Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
Published 2025-01-01“…This paper explores these relationships, starting with the evolutionary aspects of brain development in the context of physical activity. …”
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Dynamics of the evolution of the strategic management concept: From the planning school to the neostrategic approach
Published 2021-01-01“…They indicate different factors that allow for success in strategic management such as: setting long-term goals, selection of programs and their execution plans (planning school); connection of the enterprise with the environment (evolutionary school); focusing attention on competitive advantage and achieved performance (position-based school); focus on one’s own resources and competences (resource school); use of opportunities and creating innovation (simple rules school); selection of the best option and orientation in business management (real options school); or eclectic perspectives, integrating the listed approaches. …”
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1453
A comparative analysis of sequence composition in different lots of a phage display peptide library during amplification
Published 2025-02-01“…Our findings can be instrumental for phage display researchers by bringing fundamental insights into the vast extent of non-uniformity between phage display libraries and by providing a clear picture of how these discrepancies can lead to different evolutionary fates for the peptide composition of phage pools, which can have profound impacts on the outcome of phage display selections through biopanning.…”
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1454
GlucoGenes<sup>®</sup>, a database of genes and proteins associated with glucose metabolism disorders, its description and applications in bioinformatics research
Published 2025-01-01“…With GlucoGenes®, an evolutionary analysis of genes associated with glucose metabolism disorders was performed. …”
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Genetic differentiation and historical dynamics of the endemic species Rheum pumilum on the Qinghai-Tibetan Plateau inferred from phylogeography implications
Published 2025-02-01“…This study employs chloroplast DNA fragments (trnL-F, trnS-G, and matK) to delve into how Rh. pumilum adapted to the extreme environmental changes on the QTP, during its evolutionary process through phylogenetic geographical analysis, revealing its population differentiation and historical dynamics. …”
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1456
Genome-resolved year-round dynamics reveal a broad range of giant virus microdiversity
Published 2025-01-01“…ABSTRACT Giant viruses are crucial for marine ecosystem dynamics because they regulate microeukaryotic community structure, accelerate carbon and nutrient cycles, and drive the evolution of their hosts through co-evolutionary processes. Previously reported long-term observations revealed that these viruses display seasonal fluctuations in abundance. …”
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1457
Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins
Published 2006-01-01“…The natural antimicrobial peptides are ancient host defense effector molecules, present in organisms across the evolutionary spectrum. Several properties of α-melanocyte stimulating hormone (α-MSH) suggested that it could be a natural antimicrobial peptide. α-MSH is a primordial peptide that appeared during the Paleozoic era, long before adaptive immunity developed and, like natural antimicrobial molecules, is produced by barrier epithelia, immunocytes, and within the central nervous system. α-MSH was discovered to have antimicrobial activity against two representative pathogens, Staphylococcus aureus and Candida albicans. …”
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1458
Complete Genome Sequence and Comparative Genome Analysis of Variovorax sp. Strains PAMC28711, PAMC26660, and PAMC28562 and Trehalose Metabolic Pathways in Antarctica Isolates
Published 2022-01-01“…Likewise, MEGA X was used for evolutionary and conserved genes. The complete genomes of Variovorax strains PAMC28711, PAMC26660, and PAMC28562 are circular chromosomes of length (4,320,000, 7,390,000, and 4,690,000) bp, respectively, with GC content of (66.00, 66.00, and 63.70)%, respectively. …”
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1459
Host-symbiont-gene phylogenetic reconciliation
Published 2023-05-01“…Given three phylogenetic trees, we devise a Monte Carlo algorithm which samples evolutionary scenarios of symbionts and genes according to an approximation of their likelihood in the model. …”
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Spatial mismatch and congruence in the taxonomic, functional, and phylogenetic diversities of fish assemblages in China's water diversion lakes
Published 2025-03-01“…The interplay of evolutionary, ecological, and anthropogenic processes is critical in shaping species distributions and biodiversity patterns. …”
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