Machine Learning-Based Radiomics Analysis for Identifying KRAS Mutations in Non-Small-Cell Lung Cancer from CT Images: Challenges, Insights and Implications by Mirjam Schöneck, Nicolas Rehbach, Lars Lotter-Becker, Thorsten Persigehl, Simon Lennartz, Liliana Lourenco Caldeira

“…Model transferability is therefore difficult to achieve, which became evident during external testing (F1 score = 0.41). …”
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Cryoablation for advanced non-small cell lung cancer: a protocol for a systematic review by Dan Wang, Yu Chen, Hua Duan, Shu-Yue Zheng, Chufan Luo, Xueni Fang, Haoyue Pang, Man Wang, Tian Zhou, Quanwang Li, Kaiwen Hu

“…Two reviewers will independently extract data on participants, interventions, comparisons, outcomes and assess the methodological quality by the Cochrane risk of bias tool. The strength of evidences will be evaluated according to the Grading of Recommendations Assessment, Development and Evaluation approach. …”
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Preparation and in vitro biological evaluation of strontium doped β-tricalcium phosphate scaffolds for alveolar bone tissue regeneration by Congrui Liu, Guiyong Xiao, Zichen Wang, Mengchen Xu, Yinchuan Wang, Nan Wang, Zhenlong Sun, Xiaoyan Li, Yixin Yin

“…The alkaline phosphatase assay and mineralization staining confirmed the osteogenic differentiation potential of Srx-TCP in vitro, particularly evident in the Sr8-TCP scaffold. Overall, the experimental results indicate the remarkable biocompatibility and outstanding osteogenic differentiation ability of Srx-TCP scaffolds. …”
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Bone Mineral Status in Children and Adolescents with Klinefelter Syndrome by Stefano Stagi, Mariarosaria Di Tommaso, Cristina Manoni, Perla Scalini, Francesco Chiarelli, Alberto Verrotti, Elisabetta Lapi, Sabrina Giglio, Laura Dosa, Maurizio de Martino

“…Interestingly, this impairment was already evident in prepubertal KS patients. Follow-ups should be scheduled with KS patients to investigate and ameliorate bone mineral status and metabolism until the prepubertal ages.…”
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Complexed hyaluronic acid-based nanoparticles in cancer therapy and diagnosis: Research trends by natural language processing by Abd Kakhar Umar, Patanachai K. Limpikirati, Bachtiar Rivai, Ilham Ardiansah, Sriwidodo Sriwidodo, Jittima Amie Luckanagul

“…A shift in research focuses from optimizing chemical toxicity to particular targeting tactics and precise release mechanisms is evident. These findings reflect the dynamic landscape of HA-based nanoparticle research in cancer therapy, emphasizing advancements in targeted drug delivery, therapeutic efficacy, and multimodal diagnostic approaches to improve overall patient outcomes.…”
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Ecological-based insights into bat populations in the Yucatán Peninsula under a One Health approach: coexistence or biophobia by Ma. Fernanda Sánchez-Soto, Osiris Gaona, Ricardo Mercado-Juárez, Ricardo Mercado-Juárez, Alfredo Yanez-Montalvo, Arit de León-Lorenzana, Gabriela Borja-Martínez, Gabriela Borja-Martínez, Daniela Zaldívar, Stephany Rodríguez-González, Erika N. Hernández-Villegas, Andres Moreira-Soto, Jan Felix Drexler, Gerardo Suzán, Ella Vázquez-Domínguez, Luisa I. Falcón

“…During the SARS-CoV-2 pandemic, biophobic (aversive) responses towards bats were recorded in urban and rural areas of the YP, making evident the need to monitor bat diversity, investigate species’ biology (e.g., microbiome) and, perhaps most importantly, conduct educational activities that foster an affinity for bats. …”
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Impact of Mixed Sources on the Atmospheric Aerosols of Urbanized Areas in the Philippines by Preciosa Corazon B. Pabroa, Joseph Michael D. Racho, John Robin Yee, Lawrence Adrian Tacliad, Haron Deo Vargaz, Iara Chantrelle V. Coronel, Raymond J. Sugcang, Christian Mark G. Salvador

“…For Boracay, construction activities evidently enhanced PM based on the mass burden of calcium. …”
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In vivo kinematic analysis of failure cases after nonanatomical anterior cruciate ligament reconstruction: a preliminary study by Tomofumi Kage, Shuji Taketomi, Tetsuya Tomita, Takaharu Yamazaki, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Ryo Murakami, Takahiro Arakawa, Takashi Kobayashi, Hiroshi Inui, Sakae Tanaka

“…Abstract Background Nonanatomical anterior cruciate ligament (ACL) reconstruction occasionally induces ACL failure without an evident injury episode, necessitating revision surgery. …”
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The personal safety burden for women taking public transport in Australia and implications for provision of equitable public transport by Julie A. King, Dominique A. Greer, Rae S.M. Danvers, Byron W. Keating

“…The responses showed that women tended to take the public transport system as a given, and to believe they needed to take responsibility for their own safety, so that they did not nominate particular solutions for public transport providers to implement. However, it was evident that the features of public transport travel that participants felt were safer, such as the presence of trained staff, are diminishing with the move to greater use of technology and automation. …”
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Clinical and Technical Characteristics of Coronary Angiography and Percutaneous Coronary Interventions Performed before and after Transcatheter Aortic Valve Replacement with a Ball... by Alfredo Nunes Ferreira-Neto, Rishi Puri, Lluis Asmarats, Victoria Vilalta, Leonardo Guimaraes, Robert Delarochellière, Jean-Michel Paradis, Siamak Mohammadi, Eric Dumont, Josep Rodés-Cabau

“…Transcatheter aortic valve replacement (TAVR) is emerging as a treatment for younger and lower surgical risk patients who might not present with clinically evident CAD before TAVR. The demand for performing post-TAVR coronary angiograms (CAs) and percutaneous coronary interventions (PCIs) will thus increase, posing new technical challenges. …”
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Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection by Simone Giuliano, Jacopo Angelini, Floriana Campanile, Paola Conti, Sarah Flammini, Alberto Pagotto, Francesco Sbrana, Luca Martini, Denise D’Elia, Mohd H. Abdul-Aziz, Menino O. Cotta, Jason A. Roberts, Robert A. Bonomo, Carlo Tascini

“…In cases where a bactericidal effect of ceftobiprole alone was not evident, synergism with ampicillin and bactericidal activity were demonstrated instead. …”
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Epidemiological and Clinical Profile of Dermatoses Observed in Chronic Hemodialysis Patients at the National Teaching Hospital (NTH-HKM) of Cotonou, Benin by Hugues Adégbidi, Fabrice Akpadjan, Odile Houngbo, Jacques Vigan, Bérénice Dégboé, Nadège Agbessi, Christiane Koudoukpo, Félix Atadokpèdé

“…However, the presence of cutaneous signs is evident in these patients, and the need for dermatological care is not negligible. …”
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Naked-Eye Molecular Testing for the Detection of <i>Xylella fastidiosa</i> in Mallorca (Balearic Island) Almond Orchards by Colorimetric LAMP by Amoia Serafina Serena, Ana Falcón-Piñeiro, Milica Pastar, José Manuel Garcìa-Madero, Nicoletta Contaldo, Mikael Muegge, Stéphane Compant, Pasquale Saldarelli, Angelantonio Minafra

“…An overall positive agreement of about 47% was observed between the results of the two techniques, while a decrease in cLAMP sensitivity was evident as the bacterial titer declined in infected plants over Cq > 26–27. …”
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Divergent response of grassland aboveground net primary productivity and precipitation utilization efficiency to altered precipitation patterns by process-based model by Chen Cheng, Lu Wu, Lu Wu, Hongyan Liu, Boyi Liang, Xinrong Zhu, Feiyun Yang

“…The simulated ANPP shows distinctive responses to the changed rainfall characteristics, where the influence of precipitation decreasing is more evident than precipitation increasing by the same precipitation change. …”
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The Timing and Spectral Properties of the 2022 Outburst of SGR J1935+2154 Observed with NICER by Fu Yu-Cong, Lin Lin, Ge Ming-Yu, Enoto Teruaki, Hu Chin-Ping, Younes George, Göǧüş Ersin, Malacaria Christian

“…In general, the X-ray flux of the persistent emission decays exponentially. While a flare is evident on the light curve, a fast radio burst (FRB) was detected immediately following the peak of this flare. …”
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Transcriptional and Posttranscriptional Regulations of the HLA-G Gene by Erick C. Castelli, Luciana C. Veiga-Castelli, Layale Yaghi, Philippe Moreau, Eduardo A. Donadi

“…The HLA-G promoter region is different from the classical class I promoters, mainly because (i) it lacks regulatory responsive elements for IFN-γ and NF-κB, (ii) the proximal promoter region (within 200 bases from the first translated ATG) does not mediate transactivation by the principal HLA class I transactivation mechanisms, and (iii) the presence of identified alternative regulatory elements (heat shock, progesterone and hypoxia-responsive elements) and unidentified responsive elements for IL-10, glucocorticoids, and other transcription factors is evident. At least three variable sites in the 3′ untranslated region have been studied that may influence HLA-G expression by modifying mRNA stability or microRNA binding sites, including the 14-base pair insertion/deletion, +3142C/G and +3187A/G polymorphisms. …”
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Interplay between Intravitreal RvD1 and Local Endogenous Sirtuin-1 in the Protection from Endotoxin-Induced Uveitis in Rats by S. Rossi, C. Di Filippo, C. Gesualdo, F. Testa, M. C. Trotta, R. Maisto, B. Ferraro, F. Ferraraccio, M. Accardo, F. Simonelli, M. D’Amico

“…An increase of manganese superoxide dismutase and decrease of caspase 3 were evident after RvD1 treatment. In another set of experiments, the protective effects of RvD1 (1000 ng/kg) were partly abolished by the pretreatment of the rats with EX527 (10 mg/kg/day, i.p.), a specific inhibitor of SIRT1 activity, for 7 days prior to the induction of EIU in rats. …”
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Development of VTOL-configured unmanned aquatic vehicle for underwater welding applications: An innovative design and multi-perspective computational investigations by Janani Priyadharshini Veeraperumal Senthil Nathan, Manikandan Arumugam, Mahendran Rajendran, Laxana Sourirajan, Gopinath Vinayagam, Akhila Ajith Pisharam, Sundhar Baskar, Beena Stanislaus Arputharaj, Subhav Singh, Khristina Maksudovna Vafaeva, Vijayanandh Raja

“…Following the study, it is evident that the suggested model is capable of effectively addressing the stated problem of performing underwater welding operations in underwater environments, autonomously and effectively.…”
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Perception and impact of customized physical activity programs on objective physical activity parameters in prediabetes by Radhika Aditya Jadhav, G. Arun Maiya, Vidyut Rajhans, Shashikiran Umakanth, Shivashankara K N

“…Results: PA was significantly improved, which is evident in an increase in the average step count (MD = 1408), light activity duration (MD = 34.7 Min.), and moderate to vigorous PA duration (MD = 9.1 Min.). …”
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Evaluating the Effect of Particle Gradation on Concrete's Permeability, Absorption, and Ultrasonic Properties by Laid Bedadi, Abderrahmane Khechekhouche, Mehdi Jahangiri, Antonio Marcos de Oliveira Siqueira, Julio César Costa Campos, Zakaria Rahal, Ayoub Barkat, Mohamed Naoui

“…The influence of increasing dune sand content on absorption rates was evident, with increments of around 5.38%, 11.21%, 18.38%, and 25.11% relative to CSD0 concrete, after 48 hours of testing for CSD5, CSD10, CSD15, and CSD20, respectively. …”
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