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17601
Immunogenicity of RSV F DNA Vaccine in BALB/c Mice
Published 2016-01-01“…Also, sera from RSV F immunized and RSV infected mice reduced the RSV infection by 50% and 80%, respectively. Our data evidently showed that the RSV F DNA vaccine activated the Th1 biased immune response and led to the production of neutralizing antibodies, which is the desired immune response required for protection from RSV infections.…”
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17602
Dietary Fiber with Functional Properties Counteracts the Thwarting Effects of Copper Nanoparticles on the Microbial Enzymatic Activity and Short-Chain Fatty Acid Production in the...
Published 2024-11-01“…That effect was most rapidly evident with pectin, while the effect of inulin or psyllium addition exceeded that of pectin only in some cases, i.e. , α-glucosidase activity as well as content of propionic and butyric acids. …”
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17603
Mechanistic insights toward progress in alogliptin beyond glycemic control: translational perspective
Published 2025-02-01“…Recent developments have indicated potential of alogliptin in discrete pathological conditions. Emerging evidences suggest prominent cardioprotective, hepatoprotective, reno-protective, anti-inflammatory and lipid-lowering capacity of alogliptin. …”
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17604
Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
Published 2014-01-01“…In many malignant cells, the nucleolar sequestration of p53 is evident. These observations support the view that the nucleolus is involved directly in the mediation of p53 function or indirectly by the control of the localization of p53 interplayers. p53 expressed in the nuclear fraction of breast cancer cells revealed a wide spectrum of isoforms. p53 isoforms ΔNp53 (47 kDa) and Δ133p53β (35 kDa), known as dominant-negative repressors of p53 function, were detected as the most predominant variants in nuclei of invasive breast carcinoma cells. …”
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17605
Remodeling of the brain angioarchitecture in experimental chronic neurodegeneration
Published 2025-01-01“…The 3D analysis of the degenerating SNpr revealed substantial changes of the vasculature with higher density, increased diameter, and number of tortuous vessels already after 28 days, evidently continuing at 91 days. Interestingly, the vascular remodeling changes occurred without changes in the expression of endothelial tight junction proteins, vascular basement membrane proteins, or markers of angiogenesis. …”
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17606
AI-Enabled Sensing and Decision-Making for IoT Systems
Published 2021-01-01“…To facilitate research community, the proposed study presents a systematic literature review of the existing literature, organizes the evidences in a systematic way, and then analyzes it for future research. …”
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17607
Shivering Management in Spinal Anesthesia: Evaluating the Role of Ketamine: A Narrative Review
Published 2024-10-01“…Conclusions: The effectiveness of ketamine in preventing shivering after spinal anesthesia is evident from the mixed results of studies. Ketamine, regardless of dosage, can be effective in reducing shivering after spinal anesthesia based on the mentioned criteria. …”
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17608
An NR2B-Dependent Decrease in the Expression of trkB Receptors Precedes the Disappearance of Dopaminergic Cells in Substantia Nigra in a Rat Model of Presymptomatic Parkinson's Dis...
Published 2012-01-01“…At this time point, no change in the number of tyrosine hydroxylase (TH) immunoreactive (TH-IR) cells is detected, although a decrease is evident 14 days after neurotoxin injection. The decrease in TH-positive cells and trkB expression in SNc was significantly prevented by systemic administration of Ifenprodil, a specific antagonist of NR2B-containing NMDA receptors. …”
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17609
Who gets to define flourishing? Disentangling social science from theology in flourishing measurement and policy prescriptions
Published 2025-06-01“…This concern becomes even more evident in VanderWeele and colleagues’ published response and more recent work. …”
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17610
Detection and Validation of A2 Milk Suitable for Consumers Having Milk Intolerance by ELISA Method
Published 2023-12-01“…With the onset of this trend, the need for a new analysis on food safety became evident. It will be required by food control laboratories to test the absence of A1 protein in milk to be labeled as A2 milk. …”
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17611
A multi-criteria optimization for a radial heat sink with semicircular fins based on the design of experiments approach
Published 2025-02-01“…For thermal resistance, the corresponding values were 97.91 % for predicted R2, 96.70 % for adjusted R2, 94.21 % for CV, and 3.33 % for parameter separation. Therefore, it is evident that the proposed model is highly accurate in predicting semicircular radial heat sink performance, offering a robust tool for future heat sink designs and sustainable thermal management systems.…”
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17612
Clinical case of co-infection: Dengue fever and respiratory mycoplasmosis in a child
Published 2025-01-01“…Despite the fact that during the examination at the hospital in the Maldives, DENV arbovirus antigen was isolated in the blood by immunochromatographic rapid test, the course of the disease had a number of symptoms that did not conform to the classical course of the disease: catarrhal symptoms, cough, elevated C-reactive protein, and radiographic evidences of right-sided maxillary sinusitis. No improvement in the condition was observed despite the therapy administered. …”
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17613
Ocular diseases of the anterior segment and adnexa in the elderly
Published 2024-02-01“…High blood pressure (37.4%) and age-related macular degeneration (27.6%) were evident. Decreased visual acuity occurred in 69.1% and cataract was the predominant disease (43.9%). …”
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17614
Association of pre-exiting heart failure with long-term mortality and the recurrence of sepsis
Published 2025-01-01“…Mortality rates were tracked over different time periods, revealing that the mortality disparity became evident after the first year (p = 0.029). Besides, the cumulative incidence of sepsis recurrence was substantially higher in patients with a history of heart failure (p < 0.001) when deaths without recurrence were treated as competing events. …”
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17615
Modeling the effects of introducing a new antibiotic in a hospital setting: A case study
Published 2012-06-01“…Precautions have been implemented to try to prevent the growth and spread of antimicrobial resistance such as a reduction in the distribution of antibiotics and increased hand washing and barrier preventions; however, the rise of this resistance is still evident. As a result, there is a new movement to try to re-examine the need for the development of new antibiotics. …”
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17616
The Concept Of Matan Critism And Its Application In The Book Al-Tamyīz By Muslim Bin Ḥajjāj
Published 2024-11-01“…The recognition from many other hadith scholars evidences this. Furthermore, tangible proof can be observed in his work, al-Tamyīz, within this branch of knowledge. …”
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17617
Influence of Surface Roughness on a Highly Loaded Axial Compressor Stage Performance at Low Reynolds Number
Published 2021-01-01“…In addition, for all the four roughness locations, the roughness covering from the leading edge to 50% of the axial chord length on the suction surface had a relatively evident advantage in improving the compressor peak efficiency because of the better control of the LSB and wall shear stress.…”
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17618
Long-Term High Salt Intake Involves Reduced SK Currents and Increased Excitability of PVN Neurons with Projections to the Rostral Ventrolateral Medulla in Rats
Published 2017-01-01“…Evidence indicates that high salt (HS) intake activates presympathetic paraventricular nucleus (PVN) neurons, which contributes to sympathoexcitation of salt-sensitive hypertension. …”
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17619
Can Effects of a Generalized Uncertainty Principle Appear in Compact Stars?
Published 2024-12-01“…On basis of a deformed Poisson canonical algebra with a parametrized minimum length scale that induces deviations from conventional Quantum Mechanics, fundamental questions involving the consistence, evidences and proofs of this approach as a possible cure for unbounded energy divergence are outlined. …”
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17620
Mechanical Properties of Deep Variable Dip Joint Rock Mass in Reservoir Area under Wet and Dry Conditions
Published 2023-01-01“…The change rate of the morphologic parameters and the distribution of the failure cracks indicate that the stress concentration is evident in the middle of the joint plane.…”
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