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17221
Empowering pastoralist women through social innovations in Somali and Afar regions of Ethiopia
Published 2025-01-01“…This is because the existing gender-based disparities and resultant inequalities are evident in Africa, limiting women's participation and empowerment on the continent. …”
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17222
Evaluation of high-resolution snowpack simulations from global datasets and comparison with Sentinel-1 snow depth retrievals in the Sierra Nevada, USA
Published 2025-02-01“…Larger biases at the model grid scale are especially evident at high elevation but do not alter the catchment-scale snow mass accuracy. …”
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17223
α-amanitin induces hepatotoxicity via PPAR-γ inhibition and NLRP3 inflammasome activation
Published 2025-01-01“…In vivo, α-amanitin induced dose-dependent liver injury in mice, evident by elevated serum ALT and AST, and histological liver damage. …”
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17224
The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy
Published 2025-01-01“…Based on the studies regarding the antioxidant potential of oyster mushroom extract, it is evident that it has anticancer properties. The current article reviews the health benefits of edible oyster-mushroom-derived bioactive compounds, and how they specifically activate or regulate the immune system by affecting the maturation, differentiation, and proliferation of immune cells, thereby inhibiting cancer cell metastasis and growth. …”
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17225
PPAR-γ Agonists and Their Effects on IGF-I Receptor Signaling: Implications for Cancer
Published 2009-01-01“…As hyperinsulinemia is an emerging cancer risk factor, the insulin lowering action of PPAR-γ agonists may be expected to be also beneficial to reduce cancer development and/or progression. In light of these evidences, TZDs or other PPAR-γ agonists may be exploited in those tumors “addicted” to the IGF signaling and/or in tumors occurring in hyperinsulinemic patients.…”
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17226
Model-Based Control with Active Disturbance Rejection Algorithm for a Diesel Engine
Published 2023-01-01“…However, the ADRC can further improve the speed control performance evidently on the basis of the improved PID controller.…”
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17227
Young people involved in criminal justice are associated with housing instability
Published 2025-01-01“…The association between the involvement of young individuals in the criminal justice system and their absence of secure housing is evident, emphasizing the need for a comprehensive approach to address this problem effectively. …”
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17228
Multidimensional Attention-Based CNN Model for Identifying Apple Leaf Disease
Published 2023-01-01“…The accuracy of the DBNet network increases by 0.02843, 0.02412, 0.0144, and 0.0125, respectively, when compared to previous leaf disease detection models. This makes it evident that the suggested DBNet model has certain benefits over others in terms of identifying apple leaf disease.…”
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17229
Exploring the Active Constituents of <i>Andrographis paniculata</i> in Protecting the Skin Barrier and the Synergistic Effects with Collagen XVII
Published 2025-01-01“…This combination demonstrated significant synergy in maintaining skin homeostasis, which provides evidences for the development of skin-protective products.…”
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17230
Mix Design of Recycled Coarse Aggregate Self-Compacting Concrete Based on Orthogonal Test and Analysis of Mercury Intrusion Porosimetry
Published 2021-01-01“…The pore structure of nine groups of RCASCC materials has evident fractal characteristics of irregular shape. …”
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17231
Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives
Published 2022-01-01“…In relation to the control of dental plaque and oral dysbiosis responsible for periodontal disease, both nonsurgical and surgical therapy associated with proper home hygiene procedures have emerged as essential for good glycemic control. Moreover, several evidences suggest the essential role played by the control of periodontal disease in preventing the onset of the most common complications of diabetes: cardiovascular diseases, retinopathies, and other systemic diseases. …”
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17232
Downregulation of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia
Published 2018-01-01“…Similarly, decreased expression of DJ-1 and NDUFS3 and reduced mitochondria complex I activity were evident in a rat model of AS. Moreover, we showed that the interaction between DJ-1 and NDUFS3 in rat testes was weakened by ORN treatment. …”
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17233
The Flatworm Macrostomum lignano Is a Powerful Model Organism for Ion Channel and Stem Cell Research
Published 2012-01-01“…While the importance of membrane potential in stem cell maintenance, proliferation, and differentiation is evident, the mechanisms of this bioelectric control of stem cell activity are still not well understood, and the role of specific ion channels in these processes remains unclear. …”
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17234
Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality
Published 2025-01-01“…Some immune changes, such as reduced non-switched B cells and heightened neutrophil migration, were evident in earlier TNBC stages. This study comprehensively maps systemic immunity in TNBC, guiding future research on patient stratification and immunomodulation strategies.…”
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17235
Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss
Published 2015-01-01“…The field of osteoimmunology has emerged in response to the range of evidences demonstrating the close interrelationship between the immune system and bone metabolism. …”
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17236
Decentralized State Estimation Algorithm of Centralized Equivalent Precision for Formation Flying Spacecrafts Based on Junction Tree
Published 2015-01-01“…Inference on JT is a decentralized form of centralized Bayesian estimation (BE), which is a modularized three-step procedure of receiving messages, collecting evidences, and generating messages. As KF is a special case of BE, the new solution based on JT is equivalent in precision to centralized KF in theory. …”
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17237
A Modified Method for Studying Behavioral Paradox of Antioxidants and Their Disproportionate Competitive Kinetic Effect to Scavenge the Peroxyl Radical Formation
Published 2014-01-01“…The induction time of the reaction was also proposed as a parameter enabling determination of antioxidant content by optimizing and introducing other kinetic parameters in 96-well plate assays. The test evidently improves the original PRTC (peroxyl radical trapping capacity) assay in terms of the amount of chemical used, simultaneous tracking, that is, the generation of the radical taking place continually and the kinetic reduction technique (area under curve, peak value, slope, and Vmax).…”
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17238
The effect of gut microbiome-targeted therapies in nonalcoholic fatty liver disease: a systematic review and network meta-analysis
Published 2025-01-01“…BackgroundThe incidence of NAFLD is increasing. Preclinical evidences indicate that modulation of the gut microbiome could be a promising target in nonalcoholic fatty liver disease.MethodA systematic review and network meta-analysis was conducted to compare the effect of probiotics, synbiotics, prebiotics, fecal microbiota transplant, and antibiotics on the liver-enzyme, metabolic effects and liver-specific in patients with NAFLD. …”
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17239
„O pecunia totius mali regina, fraudis et doli amica...“ Peníze v kultuře středověku
Published 2010-07-01“…The Church’s mission to spread harmony in the Middle Ages evidently created the idea that money could become a means to allow the Christian to help the poor and power- less. …”
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17240
Regulation of the G1/S Transition in Hepatocytes: Involvement of the Cyclin-Dependent Kinase Cdk1 in the DNA Replication
Published 2012-01-01“…Finally, we provided strong evidences that Cdk1 expression and activation is correlated to extracellular matrix degradation upon stimulation by the pro-inflammatory cytokine TNFα leading to the identification of a new signaling pathway regulating Cdk1 expression at the G1/S transition. …”
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