Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study by Fiona Reid, Sophie Papa, John Maher, Jean-Pierre Jeannon, James Spicer, Victoria Gibson, Selvam Thavaraj, Michael Metoudi, Christopher Fisher, Nicholas Beckley-Hoelscher, Andrew Hope, Maria Elstad, Antonella Adami, Richard Beatson, Molly Sarah George, Daniela Achkova, Evangelia Williams, Sefina Arif, Abdel Douri, Marc Delord, Mike Lyne, Dharshene Shivapatham, Sakina Gooljar, Arindam Mitra, Linda Gomm, Cienne Morton, Rhonda Henley-Smith, Alice Santambrogio, Cynthia Andoniadou, Sarah Allen, Gary J R Cook, Ana C Parente-Pereira, David M Davies, Farzin Farzaneh, Anna Schurich, Teresa Guerrero-Urbano

“…Frequent treatment-related adverse events were tumor swelling, pain, pyrexias, chills, and fatigue. There was no evidence of leakage of T4+ T-cells into the circulation following intratumoral delivery, and injection of radiolabeled cells demonstrated intratumoral persistence. …”
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Hameaux et villages paysans de la période romaine en plaine d’Alsace by Antonin Nüsslein, Pascal Flotté, Mathias Higelin, Muriel Roth-Zehner

“…There is currently little evidence to enable us to evaluate the social status of the inhabitants. …”
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ALDH1L2 drives HCC progression through TAM polarization by Jiajun Li, Chi Zhang, Qingqing Zhou, Qinqin Long, Jiayi Chen, Lili Meng, Wei Tian, Yue Yang, Chao Ge, Yuting Su, Xi-Dai Long, Jun Wu, Hua Tian

“…Conclusions: These findings provide the first evidence indicating that ALDH1L2 is directly involved in tumor progression by interacting with tumor-associated macrophages through the Jak2/STAT3 signaling pathway and that ALDH1L2 may be a target molecule for HCC therapy. …”
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Hospitality Venues’ Anti-tobacco Legislation Violation in 11 Different Cities in Türkiye by Dilek Aslan, Yağmur Ünal, Sevinç Sütlü, Raika Durusoy, Mahmut Talha Uçar, Evrim Arslan, Elçin Balcı, Elif Sızan, Beyza Püren Selcan Gündoğdu, Emir Atasoy, Şeyma Duman, Selma Karabey, Özge Yaman Coşkun, Günay Saka, Hatice Nilden Arslan, İlayda Kulaç Aksu, Ceren Varer Akpınar, İsmail Erdem Erkoyun, Burak Kahraman, Elif Işık, İpek Gündoğdu, Türkan Günay, Muhammed Nur Özkan Tanrıverdi, Meryem Nisa Özdel, Rabia Cansel Çetin, Mehmet Ali Kurçer, Ümit Kamacı, Mehmet Fatih Yılmaz, Emine Baran Deniz

“…CONCLUSION: The findings provided scientific evidence that violations of Turkish anti-tobacco legislation exist in hospitality venues. …”
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Guía: Neurorrehabilitación en pacientes en estados alterados de la consciencia. Recomendaciones de la Sociedad Española de Neurorrehabilitación by E. Noé, M.D. Navarro, B. Moliner, M. O’Valle, J. Olaya, A. Maza, R. Llorens, J. Ferri, R. Rodríguez, T. Pérez, M. Bernabéu, C. Colomer, A. Gómez, C. González, A. Juárez-Belaúnde, C. López, S. Laxe, R. Pelayo, M. Ríos, I. Quemada, E. Noé Sebastián, M. Dolores Navarro Perez, B. Moliner Muñoz, M. O’Valle Rodriguez, J. Olaya Sanchez, R. Llorens Rodriguez, A. Maza Pino, J. Ferri Campos, R. Rodríguez Duarte, T. Pérez Nieves, M. Bernabeu, C. Colomer Font, A. Gomez Blanco, C. González Alted, A. Juárez Belaúnde, C. López Pascua, S. Laxe García, R. Pelayo Vergara, M. Ríos Lago, I. Quemada

“…Conclusions: This document presents 40 recommendations categorized according to the level of evidence provided by the reviewed studies. These recommendations represent a consensus among experts and pertain to various aspects related to: (1) clinical assessment; (2) complementary diagnostic tests; (3) prognosis, and (4) treatment in this specific population.…”
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Carbon footprint reduction practices in the Olympic Games: a policy mobility approach by Wesselia Isa Ngoenha

“…The mega-events database: Systematising the evidence on mega-event outcomes. Leisure Studies, 41(3), 437–445. https://doi.org/10.1080/02614367.2021.1998835 Temenos, C., & Ward, K. (2018). …”
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Presenting the model of portfolio management in investment funds based on behavioral financial variables by Seyed Mohammad Hadi Shahamat, Mahdi Mohammad Bagheri, Ali Raispour Rajabali, Mohsen Zayandeh Roudi

“…Keshavarz et al, (2021) in a research on investment strategies based on technical indicators: evidence of behavioral reactions of investors in the Tehran Stock Exchange. …”
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Towards a common approach for managing food allergy and serious allergic reactions (anaphylaxis) at school. GA2LEN and EFA consensus statement by Antoine Deschildre, Montserrat Alvaro‐Lozano, Antonella Muraro, Marcia Podesta, Debra deSilva, Mattia Giovannini, Simona Barni, Timothy E. Dribin, Mónica Sandoval‐Ruballos, Aikaterini Anagnostou, Alessandro Fiocchi, Alice Toniolo, Andrew Bird, Angel Sánchez Sanz, Anna Asarnoj, Anna Nowak‐Wegrzyn, Berber Vlieg‐Boerstra, Brian P. Vickery, Carina Venter, Caroline Nilsson, Cecilia Parente, Céline Demoulin, David M. Fleischer, Diola Bijlhout, Edward F. Knol, Eleanor Garrow, Emma E. Cook, Fallon Schultz, Francesca Lazzarotto, Francesca Mori, Gary Wong, Gideon Lack, Graham Roberts, Gustavo Andres Marino, H. N. G. Oude Elberink, Helen A. Brough, Hugh A. Sampson, Jay Lieberman, Jennifer Gerdts, Jing Zhao, Josefine Gradman, Julia E. M. Upton, Julie Wang, Kati Palosuo, Kirsi M. Järvinen, Kirsten Beyer, Kunling Shen, Laura Polloni, Lianne Mandelbaum, Luciana Kase Tanno, Lucy A. Bilaver, Marcus S. Shaker, Margitta Worm, Maria Said, Mary Kelly, Mary Jane Marchisotto, Michael Makris, Mikaela Odemyr, Montserrat Fernandez‐Rivas, Motohiro Ebisawa, Nandinee Patel, Pablo Rodríguez del Río, Pakit Vichyanond, Paul Turner, Pete Smith, Pilar Morón Gaspar, R. Sharon Chinthrajah, Rima Rachid, Roberta Bonaguro, Ruchi Gupta, Sabine Schnadt, Sakura Sato, Stefania Arasi, Stephanie Leonard, Sung Poblete, Susanne Halken, Thuy‐My Le, Guillaume Pouessel, Tracey Dunn, Victoria Cardona, Torsten Zuberbier

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Long-term ambient air pollution and the risk of major mental disorder: A prospective cohort study by Chuyu Pan, Bolun Cheng, Shiqiang Cheng, Li Liu, Xuena Yang, Peilin Meng, Xin Qi, Na Zhang, Xiaoyue Qin, Dan He, Wenming Wei, Jingni Hui, Yan Wen, Yumeng Jia, Huan Liu, Feng Zhang

“… Abstract Background Despite growing awareness of the mental health damage caused by air pollution, the epidemiologic evidence on impact of air pollutants on major mental disorders (MDs) remains limited. …”
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Le fromage en Gaule à l’âge du Fer et à l’époque romaine : état des lieux pour sa production et analyse de sa place dans le monde antique by Alain Ferdière, Jean-Marc Séguier

“…In fact, the only material evidence of this production, in sufficient numbers, are the pottery strainers known as early as protohistoric times. …”
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IGJR issue 1/2018 by IF and FRFG

“…Tepe, Markus / Vanhuysse, Pieter (2009): Are Aging OECD Welfare States on the Path to the Politics of Gerontocracy? Evidence from 18 Democracies, 1980-2002. In: Journal of Public Policy, vol. 29 (1/2009), 1-28. …”
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Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.) by Federico Giletti

“…With respect to the supply to the archaic city in the early and middle Samnite era, the evidence shows the use and spread across the main urban area of deep artesian wells, designed to intercept and capture the water present in the subsoil of Pompeii’s high ground. …”
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Targeting p62 by sulforaphane promotes autolysosomal degradation of SLC7A11, inducing ferroptosis for osteosarcoma treatment by Qiuming Zou, Xiaofeng Zhou, Jianqin Lai, Haixia Zhou, Jinxuan Su, Zhijing Zhang, Xiaosong Zhuang, Lili Liu, Ruijie Yuan, Sijia Li, Siyu Yang, Xinyi Qu, Jiezhu Feng, Yongqi Liu, Zisheng Li, Shiting Huang, Zhi Shi, Yu Yan, Zhiming Zheng, Wencai Ye, Qi Qi

“…Hence, our findings demonstrate that SFN exerts its anti-cancer effects through inducing SLC7A11-dependent ferroptosis in OS, providing compelling evidence for the application of SFN in OS treatment.…”
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First-line chemotherapy with selective internal radiation therapy for intrahepatic cholangiocarcinoma: The French ACABi GERCOR PRONOBIL cohort by Nicolas Adamus, Julien Edeline, Julie Henriques, Nadim Fares, Thierry Lecomte, Anthony Turpin, Dewi Vernerey, Mathilde Vincens, Brice Chanez, David Tougeron, Christophe Tournigand, Eric Assenat, Matthieu Delaye, Sylvain Manfredi, Olivier Bouché, Nicolas Williet, Angelique Vienot, Lorraine Blaise, Léo Mas, Cindy Neuzillet, Alice Boilève, Gaël S. Roth

“…Even though prospective randomized data would be needed to confirm these findings, we believe that this study constitutes new evidence of the potential benefit of combining SIRT with chemotherapy. …”
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Replication Study of “Visual Fixation on the Thorax Predicts Bystander Breathing Detection in Simulated Out-of-Hospital Cardiac Arrest” by Marco Pedrotti

“…In 2022, we published a simulation study (Study 1; n = 96)which found that instructing lay responders to look at chest movement enables them to detect breathing. To expand the evidence and available data on this topic, we attempted a replication (Study 2; n= 73).Methods: Participants equipped with an eye tracker entered a room where a manikin, randomly set as breathing or unbreathing, lying on the floor. …”
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Natural Resource Rent and Financial Development: Testing Financial Resource Curse Hypothesis in Iran by Majid Aghaei, Mahdieh Rezagholizadeh, mohammad abdi, rawa mosavi

“…In the case of the stock market, the NARDL results also do not provide conclusive evidence regarding the hypothesis of a resource curse in Iran's stock market due to the insignificance of the coefficients related to resource rents in the estimation of the stock market development index. …”
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No Galaxy-scale [C ii] Fast Outflow in the z = 6.72 Red Quasar HSC J1205–0000 by Mahoshi Sawamura, Takuma Izumi, Kouichiro Nakanishi, Takeshi Okuda, Michael A. Strauss, Masatoshi Imanishi, Yoshiki Matsuoka, Yoshiki Toba, Hideki Umehata, Takuya Hashimoto, Shunsuke Baba, Tomotsugu Goto, Toshihiro Kawaguchi, Kotaro Kohno, Dragan Salak, Taiki Kawamuro, Kazushi Iwasawa, Masafusa Onoue, Chien-Hsiu Lee, Kianhong Lee

“…., our improved analysis shows no hint of a broad component in the [C  ii ] line spectrum. Thus there is no evidence for a host galaxy-scale fast [C  ii ] outflow, despite the fact that J1205–0000 has fast nuclear ionized outflows seen in the rest-frame UV. …”
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Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort (MaastrICCht) by Steven J R Meex, Walther N K A van Mook, Iwan C C van der Horst, Jeanette Tas, Coen D A Stehouwer, Rob J J van Gassel, Serge J H Heines, Mark M G Mulder, Nanon F L Heijnen, Melanie J Acampo-de Jong, Julia L M Bels, Frank C Bennis, Marcel Koelmann, Rald V M Groven, Moniek A Donkers, Frank van Rosmalen, Ben J M Hermans, Otto Bekers, Astrid M L Oude Lashof, Fabian H Tijssen, Jan-Willem E M Sels, Chahinda Ghossein-Doha, Rob G H Driessen, Pieter L Kubben, Marcus L F Janssen, Gerry A F Nicolaes, Ulrich Strauch, Zafer Geyik, Thijs S R Delnoij, Kim H M Walraven, Jeanine A M C F Verbunt, Susanne van Santen, Ronny M Schnabel, Marcel J H Aries, Marcel C G van de Poll, Bas C T van Bussel, Joachim E Wildberger, Sander M J van Kuijk, Dennis C J J Bergmans, Paul H M Savelkoul, Alma M A Mingels, Wolfgang F F A Buhre

“…Additionally, we create a flexible design, so that additional measures can be added during the ongoing study based on new knowledge obtained from the rapidly growing body of evidence. The spread of the COVID-19 pandemic requires the swift implementation of observational research to unravel heterogeneity of the natural course of the disease of SARS-CoV-2 infection in mechanically ventilated patients. …”
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Association between plasma perfluoroalkyl substances and high-grade serous ovarian cancer overall survival: A nested case-control study by Wei-Yi Xing, Fang-Hua Liu, Dong-Dong Wang, Jia-Ming Liu, Wen-Rui Zheng, Jia-Xin Liu, Lang Wu, Yue-Yang Zhao, He-Li Xu, Yi-Zi Li, Yi-Fan Wei, Dong-Hui Huang, Xiao-Ying Li, Song Gao, Qi-Peng Ma, Ting-Ting Gong, Qi-Jun Wu

“…Background: Although evidence suggests that perfluoroalkyl and polyfluoroalkyl substances (PFASs) are positively correlated to several disease risks, no studies have proven if plasma PFASs are related to ovarian cancer survival. …”
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Cardiovascular risk assessment: Missing albuminuria contributing to gender inequality by Patricia de Sequera, Javier Arias, Borja Quiroga, María Benavent, Fabio Procaccini, Iago Romero, Guillermo López, Javier Diez, Alberto Ortiz

“…The European Society Cardiology (ESC) guidelines, he European Renal Association (ERA) Council and the Spanish Society of Nephrology (S.E.N.) in collaboration with 15 Scientific Societies recommend assessing albuminuria in all these populations.We have evaluated current clinical practice regarding the assessment of CVD risk factors (blood pressure, albuminuria, serum cholesterol, glycemia and creatinine) in different adult health user populations, analyzing the results separately for men and women, given recent evidence on gender differences in the recognition, monitoring, and management of CKD. …”
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