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16281
A Meta-analysis of acupoint application in the treatment of dysphagia after stroke (穴位贴敷治疗脑卒中后吞咽障碍的Meta分析)
Published 2023-07-01“…However, the quality and quantity of the literature included in the analysis are limited, and high-quality, large-sample double-blind randomized controlled trials are still needed to provide higher level of evidence. (目的 系统评价穴位敷贴治疗卒中后吞咽障碍的疗效。方法 计算机检Cochrane Library、Web of Science、PubMed、Embase、中国知网(CNKI)、维普数据库(VIP)、万方数据库(Wanfang Data)、中国生物医学文献数据库(CMB)中关于穴位敷贴治疗卒中后吞咽障碍的研究, 检索时限均为数据库建立至2023年1月31日。…”
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16282
Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomizatio...
Published 2025-01-01“…Moreover, bidirectional Mendelian randomization analyses provide supporting evidence for a potential causal relationship between TET2-related CHIP and the development of T2DM. …”
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16283
Bug off or bug out: mapping flight secrets of Triatoma garciabesi (Hemiptera: Reduviidae) through climate, geography, and greenery
Published 2025-01-01“…This study provides evidence for this by showing clear variation in flight-related traits across the species and lineage distribution range, as well as indications of isolation by distance and variation in flight-related traits according to climate, geography, and vegetation cover.…”
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16284
A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions
Published 2025-01-01“…The task force met biweekly over 14 months, to evaluate published evidence, examine the possible contribution of each “omics” technique to the study of PASC and develop study design recommendations. …”
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16285
Genetic determinants of COVID-19 severity and mortality: ACE1 Alu 287 bp polymorphism and ACE1, ACE2, TMPRSS2 expression in hospitalized patients
Published 2025-01-01“…Background The angiotensin-converting enzyme 2 (ACE2) and the transmembrane serine protease 2 (TMPRSS2) are central human molecules in the SARS-CoV-2 virus-host interaction. Evidence indicates that ACE1 may influence ACE2 expression. …”
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16286
Phase IV adaptive randomised clinical trials evaluating efficacy and cost-efficacy of pre-emptive pharmacogenetic genotyping strategies in the Spanish National Health System: iPHAR...
Published 2024-11-01“…However, the adoption of pre-emptive pharmacogenetic testing for commonly prescribed drugs, such as statins, outside of tertiary hospitals is limited due to a lack of pharmacoeconomic evidence to support widespread implementation by healthcare policy-makers. …”
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16287
Les effets des normes de sexe chez les enseignant-e-s de l’école primaire
Published 2011-01-01“…Les effets des normes de sexe chez les enseignant-e-s de l’école primaire Dans cet article, je propose de rendre compte des rôles de sexe joués par les enseignant-e-s intervenant à l’école primaire dans la construction sociale et culturelle sur leur identité professionnelle, et par conséquent, de mettre en évidence comment les normes de sexe peuvent régir ces identités professionnelles de sexe.Le corps des enseignant-e-s de l’école primaire est composé de 79% de femmes en 2005 et ceci malgré les discriminations favorisant le recrutement des hommes jusqu’en 1987 (Charles F. et alii, 1997). …”
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16288
Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning.
Published 2021-07-01“…Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. …”
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16289
Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial
Published 2019-05-01“…No related serious adverse events were reported.Conclusion There was no evidence of a difference in efficacy between topical medical grade kanuka honey and 5% aciclovir in the pharmacy-based treatment of herpes simplex labialis.Trial registration number ACTRN12615000648527;Post-results…”
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16290
Safety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta...
Published 2025-01-01“…The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system was used to assess the certainty of evidence for each pooled analysis. PROSPERO registration: CRD42024547905. …”
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16291
Analyzing the Influence of Company's Business Strategy and Its Components as a Factor of Information Risk on Excess Stock Returns
Published 2024-12-01“…These findings contribute to the existing financial literature by providing empirical evidence on the role of business strategy as an information risk factor and its impact on excess stock returns. …”
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16292
CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context
Published 2025-01-01“…For each new or modified checklist item, we provide a detailed description and its rationale with supporting evidence, and present examples from EPDF trial reports published in peer-reviewed scientific journals. …”
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16293
Sex and outcomes of patients with microsatellite instability-high and BRAF V600E mutated metastatic colorectal cancer receiving immune checkpoint inhibitors
Published 2025-02-01“…A significant proportion of patients show resistance, making the identification of determinants of response crucial. Growing evidence supports the role of sex in determining susceptibility to anticancer therapies, but data is lacking for patients with MSI-H CRC.Methods In this real-world cohort comprising 624 patients with MSI-H mCRC receiving ICIs, we investigated the impact of sex on patients’ outcomes, overall and according to RAS-BRAF mutational status or type of treatment (anti-PD-(L)1 with or without anti-CTLA-4 agents). …”
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16294
AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection
Published 2025-02-01“…However, their prognostic value in hepatocellular carcinoma (HCC) remains controversial, with different evidence. Given the heterogeneous outcomes in patients with HCC undergoing liver resection, this study aims to develop an AI-based system to quantify CD8+ TILs and assess their prognostic value for patients with HCC. …”
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16295
Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ...
Published 2022-07-01“…Dexamethasone therapy was weakly associated with a reduction in mortality in both those with proven bacterial meningitis (aOR 0.57, 95% CI 0.28 to 1.17) and with pneumococcal meningitis (aOR 0.47, 95% CI 0.20 to 1.10).Conclusion This study demonstrates that clinical care for patients with meningitis in the UK is not in line with current evidence-based national guidelines. Diagnostics and therapeutics should be targeted for quality improvement strategies. …”
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16296
Effectiveness of the BNT162b2 XBB.1.5-adapted vaccine against COVID-19 hospitalization related to the JN.1 variant in Europe: a test-negative case-control study using the id.DRIVE...
Published 2025-01-01“…Interpretation: BNT162b2 XBB.1.5-adapted vaccine provided protection against JN.1-related hospitalization, regardless of prior vaccination history, with no evidence of waning through five months. These data support yearly vaccination against COVID-19 to prevent severe illness during the respiratory virus season. …”
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16297
Pierre et carrières dans la Saintonge antique : identification, usages et diffusion
Published 2022-12-01“…The major role played by the quarries of Thénac, Saint-Vaize and Pons in monumental construction is evident in the early days of Roman colonisation. The settlements of Saintes and Barzan (Charente-Maritime) present recurrent evidence of this. …”
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16298
Guideline: Neurorehabilitation in patients with disorder of consciousness. Recommendations from the Spanish Society of Neurorehabilitation
Published 2025-01-01“…Conclusions: This document presents 40 recommendations categorised according to the level of evidence provided by the reviewed studies. These recommendations represent a consensus among experts and pertain to various aspects related to: 1) clinical assessment, 2) complementary diagnostic tests, 3) prognosis, and 4) treatment in this specific population. …”
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16299
Petrogenesis of Intrusive body in Northeast of Joveinan, North of Isfahan, Urumieh- Dokhtar magmatic zone
Published 2024-10-01“…Field and petrographic evidence such as a lack of thermal metamorphism and graphic texture suggests that the rocks crystallized at a shallow depth. …”
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16300
Atg5 deficiency in basophils improves metabolism in lupus mice by regulating gut microbiota dysbiosis
Published 2025-01-01“…Elucidating the crosstalk among the immune system, commensal microbiota, and metabolites is crucial to understanding the pathogenesis of autoimmune diseases. Emerging evidence shows that basophil activation plays a critical role in the pathogenesis of SLE; however, the underlying mechanisms remain largely unknown. …”
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