Weight trajectories in aging humanized APOE mice with translational validity to human Alzheimer's risk population: A retrospective analysis. by Francesca Vitali, Jean-Paul Wiegand, Lillian Parker-Halstead, Allan Tucker, Roberta Diaz Brinton

“…Because change in weight is a well-documented precursor of AD, we investigated whether diversity of human AD risk weight phenotypes was evident in a longitudinally characterized cohort of 1,196 female and male humanized APOE (hAPOE) mice, monitored up to 28 months of age which is equivalent to 81 human years. …”
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circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis by Qing Lv, Qinghua Xia, Anshu Li, Zhiyong Wang

“…Results. circRNA_101277 was increased in CRC tissues compared with control samples. circRNA_101277 overexpression was evident in CRC cells, and knockdown of this circRNA suppressed cellular proliferation and cisplatin resistance in these cancer cells. …”
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Effect of electroacupuncture on symptoms of female pelvic organ prolapse (stage II–III) (EAPOP study): protocol of a randomised controlled trial by Yan Yan, Zhishun Liu, Huan Chen, Xiaoxu Liu, Hangyu Shi

“…Although studies indicated that electroacupuncture (EA) may be effective in improving the POP symptoms, evidences were not robust. Therefore, this study aims to conduct a randomised controlled trial (RCT) to evaluate the efficacy and safety of electroacupuncture on relieving symptoms of a POP stage II and III among women.Methods and analysis A two-arm, multicentre, patient-blind RCT will be conducted to compare EA with sham electroacupuncture (SEA) for treating symptoms of POP stage II and III among women in six tertiary hospitals in China. …”
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Evaluation of the effect of SmearOFF on Smear Layer Removal and Erosion of Root Canal Dentin by Sohela Fakher Mahdi, Diyar Khalid Bakr

“…For erosion variable, erosion was most evident in G4 (6% NaOCL/ 17% EDTA). There were no significant differences between G2 and G3 and also between G3 and G4 in both smear layers and erosion. …”
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The Anti-proliferative Effect of a Novel Glutaminase Inhibitor IN-3 on Prostate Cancer Cells by Ummuhan DEMIR, Ayse Busranur CELIK

“…The dose dependent effect of IN-3 was evident even in low concentration with 1 μM in LNCaP and 2 μM in PC-3 and these anti-proliferative effects of IN-3 were highly significant with p-values lower than 0.0001. …”
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Health data sharing in Germany: individual preconditions, trust and motives by Elias Kühnel, Felix Wilke

“…Regarding the factors influencing the willingness to share data with research institutions, three overarching factors can be named: (1) individual characteristics, in particular the level of education and technical competence, (2) individual motives, such as altruism as well as worries and concerns regarding health data sharing, and (3) trust in institutions, especially trust in science and technology companies.Discussion and conclusionAlthough the study shows a general openness towards sharing health data and underlines the importance of altruistic motives, social inequalities and concerns about health data sharing are also evident. Trust plays a particularly important role here, as it acts as a mediator between individual preconditions and individual motives. …”
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Effects of Periodontal Endoscopy-Assisted Nonsurgical Treatment of Periodontitis: Four-Month Results of a Randomized Controlled Split-Mouth Pilot Study by Christian Graetz, Johanna Sentker, Miriam Cyris, Susanne Schorr, Claudia Springer, Karim M. Fawzy El-Sayed

“…There are significantly longer TrT p<0.001 and more surfaces with subgingival HDs evident in PE at T0 p=0.001. Conclusion. Whereas subgingival HDs can be visually detected with PE during NSPT, no additional clinical benefits regarding BOP, PD, or CAL were notable compared to conventional systematic periodontal instrumentation. …”
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The Influence of Marketing Mix and Cafe Atmosphere on Customer Loyalty Through Customer Satisfaction As a Mediation Variable by M. Risal, Achmad Efendi, Adi Firmanzah

“…Background: The development of cafes and restaurants represents one of the fastest-growing sectors in Indonesia's culinary industry. This growth is evident not only in major cities but also in remote areas. …”
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Sky High or Grounded: Nest Site Selection of Herons and Egrets in a Mixed‐Species Colony by Farrah Samraoui, Riad Nedjah, Abdennour Boucheker, Hamed A. El‐Serehy, Boudjéma Samraoui

“…Vertical stratification was evident among the heron species; however, contrary to long‐standing assumptions, it was not directly related to body size. …”
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Prevalence of gentle herpes simplex type 2 in Babylon province for last 3 years: A retrospective descriptive data analysis by Ammar Abbas Shalan, Nada Khazal K. Hindi, Mohammed Malih Radhi, Zainab Adil Ghani Chabuck

“…Older individuals displayed higher prevalence (p = 0.002), while a profound gender influence was evident, with females displaying a significantly greater prevalence (p = 0.000). …”
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A Mixed Reality–Based Telesupervised Ultrasound Education Platform on 5G Network Compared to Direct Supervision: Prospective Randomized Pilot Trial by Minha Kim, Meong Hi Son, Suhyeon Moon, Won Chul Cha, Ik Joon Jo, Hee Yoon

“…ResultsImage quality scores and procedure times showed no significant differences between the groups (TG: 66.8 [SD 10.3] vs DG: 66.8 [SD 10.4], PPPPPPPPP ConclusionsAlthough no significant differences in image quality scores were observed between groups, considerable differences in positive educational interactions, workload, and usability were evident. These findings emphasize the platform’s potential to enhance the ultrasound training experience, suggesting more interactive and efficient learning.…”
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Knockdown of PTEN promotes colon cancer progression and induces M2 macrophage polarization in the colon cancer cell environment by Xu Han, Ting Yan, Lina Wang, Bin He, Huaxu Yu

“…Materials and Methods and Results: The expression of PTEN in colon cancer tissues and colon cancer cells was significantly lower than in precancerous tissues or CCD-18Co cells, and the decrease was most evident in SW620 cells. The expressions of phosphate (p)-p38, c-Jun N-terminal kinase (JNK), activator protein 1 (AP-1), B-cell lymphoma-2 (Bcl-2) protein in colon cancer tissues and cells were significantly higher than in precancerous tissues or CCD-18Co cells (P-values < 0.05). …”
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Extracellular Vesicle-Loaded Oncogenic lncRNA NEAT1 from Adipose-Derived Mesenchymal Stem Cells Confers Gemcitabine Resistance in Pancreatic Cancer via miR-491-5p/Snail/SOCS3 Axis by Rongxiang Wu, Zhan Su, Le Zhao, Ruifeng Pei, Yiren Ding, Deqiang Li, Shuo Zhu, Lu Xu, Wei Zhao, Wuyuan Zhou

“…It is becoming increasingly evident that key mechanisms of mesenchymal stem cell (MSC) efficacy appear to associate with paracrine activities, and the delivery of cargos through extracellular vesicles (EVs) controls the mechanistic actions of MSCs. …”
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Effects of <i>Serendipita indica</i> on the Morphological and Physiological Characteristics of <i>Agrostis stolonifera</i> L. Under Drought Stress by Chuhong Lin, Wenxu Hu, Xin Qin, Yongjun Fei, Die Hu

“…These improvements were evident in both aboveground and underground parts, leaf relative water content, total root length, and root surface area after 25 days of drought treatments. …”
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Experimental Study of Volumetric Fracturing Properties for Shale under Different Stress States by Hongjian Wang, Jin Li, Fei Zhao, Jinyu Dong, Yanzong Cui, Wanlin Gong

“…Additionally, when the lateral in situ stress difference coefficient is smaller, the rock specimen has an evident trend to form more complex cracks. When the shale rock was subjected to lateral disturbance loads, the critical failure strength was approximately 10 MPa less than that in the state of constant loading, indicating that the specimen with disturbance loads is more likely to be fractured. …”
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Prevalence of Strabismus among Patients Attending Basrah Teaching Hospital, Basrah, Iraq by Mohammed Al Ashoor, Hamid Al Taha

“…Each participant underwent comprehensive ophthalmological examinations to assess strabismus, evident through their various characteristics. The patients were divided into two main groups: Concomitant and incomitant groups. …”
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Correlation of sarcopenia with progression of liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease: a study from two cohorts in China and the Un... by Fan Zhang, Longgen Liu, Wenjian Li

“…Additionally, a non-linear feature was evident in some liver fibrosis indicators. Subgroup analysis further corroborated the finding that the harmful effect of sarcopenia on liver fibrosis was consistent across all identified subgroups. …”
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Leveraging on large language model to classify sentences: a case study applying STAGES scoring methodology for sentence completion test on ego development by Xavier Bronlet

“…The robustness of aggregated data is particularly evident when calculating ego development scores for individuals, groups, corporate units, and entire corporations. …”
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The Content-Validated Geometry Lessons in Islam Observed Brain-based Learning by Sherma O. Sappari, Florante P. Ibarra, Amirul Mukminin, Kasinyo Harto, Lenny Marzulina, Herri Mulyono, Asmendri Asmendri

“…Results indicated that substantive theory on the process of learning geometry in content-validated lessons with Islamic value-infusions as perceived  to have brain-based learning was evidently observed which revolved on five sub-elements: (a) connection; (b) attention;(c) imagination and action; (d) emotions and recollection; and (e) associations. …”
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Influence of Cavity Width on Attenuation Characteristic of Gas Explosion Wave by Dengke Xu, Chaomin Mu, Zhongqing Li, Wenqing Zhang

“…Cavities with various width sizes, namely, 500 ∗300 ∗200, 500 ∗500 ∗200, and 500 ∗800 ∗200 (length ∗width ∗height, unit: mm), were experimented to further investigate the attenuation characteristics through a self-established large-size pipe gas explosion experimental system with 200 mm diameter and 36 m length. Results showed an evident attenuation effect on flame duration light intensity (FDLI) and peak overpressure with increasing cavity width. …”
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